{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T13:18:12Z","timestamp":1784899092009,"version":"3.55.0"},"reference-count":79,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T00:00:00Z","timestamp":1455062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0147739","type":"journal-article","created":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T19:14:49Z","timestamp":1455131689000},"page":"e0147739","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Serum Autoantibodies in Chronic Prostate Inflammation in Prostate Cancer Patients"],"prefix":"10.1371","volume":"11","author":[{"given":"Bettina","family":"Schlick","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Massoner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelika","family":"Lueking","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pornpimol","family":"Charoentong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjam","family":"Blattner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Schaefer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Marquart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Theek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Amersdorfer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Zielinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Kirchner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zlatko","family":"Trajanoski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Rubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"M\u00fcllner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Schulz-Knappe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Klocker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,2,10]]},"reference":[{"issue":"9360","key":"ref1","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0140-6736(03)12713-4","article-title":"Prostate cancer epidemiology","volume":"361","author":"H Gronberg","year":"2003","journal-title":"Lancet"},{"issue":"Suppl 9","key":"ref2","first-page":"S3","article-title":"Pathophysiology, epidemiology, and natural history of benign prostatic hyperplasia","volume":"6","author":"H Lepor","year":"2004","journal-title":"Reviews in urology"},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"214","DOI":"10.4103\/0970-1591.126909","article-title":"BPH and prostate cancer risk","volume":"30","author":"S Miah","year":"2014","journal-title":"Indian journal of urology: IJU: journal of the Urological Society of India"},{"issue":"3","key":"ref4","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1038\/pcan.2013.11","article-title":"The incidence of acute urinary retention secondary to BPH is increasing among California men","volume":"16","author":"HK Groves","year":"2013","journal-title":"Prostate cancer and prostatic diseases"},{"issue":"6","key":"ref5","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/j.ejca.2012.12.027","article-title":"Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012","volume":"49","author":"J Ferlay","year":"2013","journal-title":"Eur J Cancer"},{"issue":"6","key":"ref6","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1111\/j.1464-410X.2011.10365.x","article-title":"The economic burden of prostate cancer","volume":"108","author":"CG Roehrborn","year":"2011","journal-title":"BJU international"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/pros.10084","article-title":"Increased expression of lymphocyte-derived cytokines in benign hyperplastic prostate tissue, identification of the producing cell types, and effect of differentially expressed cytokines on stromal cell proliferation","volume":"52","author":"G Kramer","year":"2002","journal-title":"The Prostate"},{"issue":"16","key":"ref8","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1002\/pros.21027","article-title":"Inflammation in benign prostatic hyperplasia: a 282 patients&apos; immunohistochemical analysis","volume":"69","author":"G Robert","year":"2009","journal-title":"The Prostate"},{"issue":"3","key":"ref9","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1038\/bjc.1990.87","article-title":"An immunohistochemical characterisation of the inflammatory cell infiltrate in benign and malignant prostatic disease","volume":"61","author":"S McClinton","year":"1990","journal-title":"British journal of cancer"},{"issue":"9","key":"ref10","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1046\/j.1464-410x.1999.00352.x","article-title":"Asymptomatic inflammation and\/or infection in benign prostatic hyperplasia","volume":"84","author":"JC Nickel","year":"1999","journal-title":"BJU international"},{"issue":"Suppl 1","key":"ref11","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3109\/0284186X.2010.522197","article-title":"Screening for prostate cancer\u2014-the controversy continues, but can it be resolved?","volume":"50","author":"M Bul","year":"2011","journal-title":"Acta Oncol"},{"issue":"6","key":"ref12","article-title":"Screening for prostate cancer with PSA testing: current status and future directions","volume":"25","author":"JM Croswell","year":"2011","journal-title":"Oncology (Williston Park)"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-0-12-801401-1.00001-3","article-title":"PSA in screening for prostate cancer: more good than harm or more harm than good?","volume":"66","author":"MJ Duffy","year":"2014","journal-title":"Advances in clinical chemistry"},{"issue":"5","key":"ref14","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1016\/j.juro.2010.12.058","article-title":"Prostatic inflammation detected in initial biopsy specimens and urinary pyuria are predictors of negative repeat prostate biopsy","volume":"185","author":"K Fujita","year":"2011","journal-title":"The Journal of urology"},{"issue":"11","key":"ref15","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1001\/jama.2014.2085","article-title":"Screening for prostate cancer with the prostate-specific antigen test: a review of current evidence","volume":"311","author":"JH Hayes","year":"2014","journal-title":"JAMA: the journal of the American Medical Association"},{"issue":"4","key":"ref16","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/nrc2090","article-title":"Inflammation in prostate carcinogenesis","volume":"7","author":"AM De Marzo","year":"2007","journal-title":"Nature reviews Cancer"},{"issue":"1","key":"ref17","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.eururo.2011.03.055","article-title":"The controversial relationship between benign prostatic hyperplasia and prostate cancer: the role of inflammation","volume":"60","author":"C De Nunzio","year":"2011","journal-title":"European urology"},{"issue":"1","key":"ref18","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1365-2559.2011.04033.x","article-title":"Prostate cancer and inflammation: the evidence","volume":"60","author":"KS Sfanos","year":"2012","journal-title":"Histopathology"},{"issue":"5","key":"ref19","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.urolonc.2007.05.007","article-title":"Inflammation, atrophy, and prostate carcinogenesis","volume":"25","author":"AM De Marzo","year":"2007","journal-title":"Urologic oncology"},{"issue":"6","key":"ref20","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.cell.2010.01.025","article-title":"Immunity, inflammation, and cancer","volume":"140","author":"SI Grivennikov","year":"2010","journal-title":"Cell"},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1097\/CJI.0b013e3182518e83","article-title":"Cancer and innate immune system interactions: translational potentials for cancer immunotherapy","volume":"35","author":"Y Liu","year":"2012","journal-title":"J Immunother"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"574981","DOI":"10.1155\/2014\/574981","article-title":"Use of autoantibodies to detect the onset of breast cancer","volume":"2014","author":"J Lacombe","year":"2014","journal-title":"Journal of immunology research"},{"issue":"8","key":"ref23","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1586\/14737140.6.8.1215","article-title":"Use of autoantibodies in breast cancer screening and diagnosis","volume":"6","author":"SJ Storr","year":"2006","journal-title":"Expert review of anticancer therapy"},{"issue":"42","key":"ref24","doi-asserted-by":"crossref","first-page":"5026","DOI":"10.1038\/onc.2012.532","article-title":"A novel approach to biomarker discovery in head and neck cancer using an autoantibody signature","volume":"32","author":"N Russo","year":"2013","journal-title":"Oncogene"},{"issue":"11","key":"ref25","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1158\/1055-9965.EPI-07-0318","article-title":"Autoantibody approach for serum-based detection of head and neck cancer","volume":"16","author":"HS Lin","year":"2007","journal-title":"Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology"},{"issue":"14","key":"ref26","doi-asserted-by":"crossref","first-page":"3862","DOI":"10.1158\/1078-0432.CCR-14-0652","article-title":"Neural autoantibody clusters aid diagnosis of cancer","volume":"20","author":"ES Horta","year":"2014","journal-title":"Clinical cancer research: an official journal of the American Association for Cancer Research"},{"issue":"14","key":"ref27","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1158\/1078-0432.CCR-10-0193","article-title":"Development of autoantibody signatures as novel diagnostic biomarkers of non-small cell lung cancer","volume":"16","author":"L Wu","year":"2010","journal-title":"Clinical cancer research: an official journal of the American Association for Cancer Research"},{"issue":"1","key":"ref28","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/ajg.2013.384","article-title":"Autoantibodies as potential biomarkers for the early detection of esophageal squamous cell carcinoma","volume":"109","author":"YW Xu","year":"2014","journal-title":"The American journal of gastroenterology"},{"issue":"9","key":"ref29","doi-asserted-by":"crossref","first-page":"2696","DOI":"10.1158\/1078-0432.CCR-07-2021","article-title":"Profiling tumor-associated autoantibodies for the detection of colon cancer","volume":"14","author":"Y Ran","year":"2008","journal-title":"Clinical cancer research: an official journal of the American Association for Cancer Research"},{"issue":"5\u20136","key":"ref30","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.cca.2011.11.027","article-title":"Autoantibody signatures as biomarkers to distinguish prostate cancer from benign prostatic hyperplasia in patients with increased serum prostate specific antigen","volume":"413","author":"DJ O'Rourke","year":"2012","journal-title":"Clinica chimica acta; international journal of clinical chemistry"},{"issue":"4","key":"ref31","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/pros.21444","article-title":"Serum-autoantibodies for discovery of prostate cancer specific biomarkers","volume":"72","author":"P Massoner","year":"2012","journal-title":"The Prostate"},{"issue":"7","key":"ref32","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/j.1464-410X.2008.07502.x","article-title":"Tyrol Prostate Cancer Demonstration Project: early detection, treatment, outcome, incidence and mortality","volume":"101","author":"G Bartsch","year":"2008","journal-title":"BJU international"},{"issue":"1\u20132","key":"ref33","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jneuroim.2011.08.013","article-title":"Investigation of autoantibody profiles for cerebrospinal fluid biomarker discovery in patients with relapsing-remitting multiple sclerosis","volume":"242","author":"NH Beyer","year":"2012","journal-title":"Journal of neuroimmunology"},{"issue":"2","key":"ref34","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1002\/pmic.200401293","article-title":"Profiling humoral autoimmune repertoire of dilated cardiomyopathy (DCM) patients and development of a disease-associated protein chip","volume":"6","author":"S Horn","year":"2006","journal-title":"Proteomics"},{"issue":"9","key":"ref35","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1074\/mcp.T500004-MCP200","article-title":"Profiling of alopecia areata autoantigens based on protein microarray technology","volume":"4","author":"A Lueking","year":"2005","journal-title":"Molecular & cellular proteomics: MCP"},{"issue":"1","key":"ref36","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.canlet.2008.11.009","article-title":"A common repertoire of autoantibodies is shared by cancer and autoimmune disease patients: Inflammation in their induction and impact on tumor growth","volume":"281","author":"R Bei","year":"2009","journal-title":"Cancer letters"},{"issue":"10","key":"ref37","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1074\/mcp.R600010-MCP200","article-title":"Tumor-associated antigen arrays for the serological diagnosis of cancer","volume":"5","author":"CA Casiano","year":"2006","journal-title":"Molecular & cellular proteomics: MCP"},{"issue":"5","key":"ref38","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1002\/(SICI)1097-0215(19980529)76:5<652::AID-IJC7>3.0.CO;2-P","article-title":"Characterization of human colon cancer antigens recognized by autologous antibodies","volume":"76","author":"MJ Scanlan","year":"1998","journal-title":"International journal of cancer Journal international du cancer"},{"issue":"2","key":"ref39","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.semarthrit.2004.07.002","article-title":"Autoantibody explosion in systemic lupus erythematosus: more than 100 different antibodies found in SLE patients","volume":"34","author":"Y Sherer","year":"2004","journal-title":"Seminars in arthritis and rheumatism"},{"issue":"7","key":"ref40","first-page":"1777","article-title":"p53 Antibodies in the sera of patients with various types of cancer: a review","volume":"60","author":"T Soussi","year":"2000","journal-title":"Cancer research"},{"issue":"3","key":"ref41","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1074\/mcp.M700263-MCP200","article-title":"Humoral response profiling reveals pathways to prostate cancer progression","volume":"7","author":"BS Taylor","year":"2008","journal-title":"Molecular & cellular proteomics: MCP"},{"issue":"12","key":"ref42","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1056\/NEJMoa051931","article-title":"Autoantibody signatures in prostate cancer","volume":"353","author":"X Wang","year":"2005","journal-title":"The New England journal of medicine"},{"issue":"2","key":"ref43","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/bioinformatics\/19.2.185","article-title":"A comparison of normalization methods for high density oligonucleotide array data based on variance and bias","volume":"19","author":"BM Bolstad","year":"2003","journal-title":"Bioinformatics"},{"issue":"2","key":"ref44","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.mbs.2012.12.007","article-title":"Statistical properties of the quantile normalization method for density curve alignment","volume":"242","author":"S Gallon","year":"2013","journal-title":"Mathematical biosciences"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.patrec.2005.10.010","article-title":"An introduction to ROC analysis","volume":"27","author":"T Fawcett","year":"2006","journal-title":"Pattern Recognition Letters"},{"issue":"1","key":"ref46","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"W Huang da","year":"2009","journal-title":"Nature protocols"},{"issue":"1","key":"ref47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/nar\/gkn923","article-title":"Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists","volume":"37","author":"W Huang da","year":"2009","journal-title":"Nucleic acids research"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/978-1-59745-545-9_4","article-title":"Tissue microarrays","volume":"576","author":"AM Dancau","year":"2010","journal-title":"Methods Mol Biol"},{"issue":"9","key":"ref49","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1136\/jcp.48.9.876","article-title":"A &quot;quickscore&quot; method for immunohistochemical semiquantitation: validation for oestrogen receptor in breast carcinomas","volume":"48","author":"S Detre","year":"1995","journal-title":"Journal of clinical pathology"},{"issue":"9","key":"ref50","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"MW Pfaffl","year":"2001","journal-title":"Nucleic acids research"},{"issue":"6","key":"ref51","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/ng.2279","article-title":"Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer","volume":"44","author":"CE Barbieri","year":"2012","journal-title":"Nature genetics"},{"issue":"1","key":"ref52","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1593\/neo.131704","article-title":"SPOP mutations in prostate cancer across demographically diverse patient cohorts","volume":"16","author":"M Blattner","year":"2014","journal-title":"Neoplasia"},{"issue":"9","key":"ref53","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1046\/j.1464-410x.2001.02193.x","article-title":"Consensus development of a histopathological classification system for chronic prostatic inflammation","volume":"87","author":"JC Nickel","year":"2001","journal-title":"BJU international"},{"issue":"9","key":"ref54","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1097\/NEN.0b013e31822c256d","article-title":"Microtubule-severing ATPase spastin in glioblastoma: increased expression in human glioblastoma cell lines and inverse roles in cell motility and proliferation","volume":"70","author":"E Draberova","year":"2011","journal-title":"J Neuropathol Exp Neurol"},{"issue":"12","key":"ref55","doi-asserted-by":"crossref","first-page":"2778","DOI":"10.1002\/jnr.21238","article-title":"Spastin and microtubules: Functions in health and disease","volume":"85","author":"S Salinas","year":"2007","journal-title":"Journal of neuroscience research"},{"key":"ref56","article-title":"Spastin mutation screening in Chinese patients with pure hereditary spastic paraplegia","author":"QQ Wei","year":"2014","journal-title":"Parkinsonism Relat Disord"},{"key":"ref57","article-title":"Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex","author":"D Jia","year":"2014","journal-title":"Hepatology"},{"issue":"4","key":"ref58","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.ccr.2014.02.007","article-title":"SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer","volume":"25","author":"G Li","year":"2014","journal-title":"Cancer cell"},{"key":"ref59","article-title":"The emerging role of speckle-type POZ protein (SPOP) in cancer development","author":"RS Mani","year":"2014","journal-title":"Drug discovery today"},{"issue":"1","key":"ref60","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.canlet.2008.07.014","article-title":"Effective stimulation of growth in MCF-7 human breast cancer cells by inhibition of syntaxin18 by external guide sequence and ribonuclease P","volume":"272","author":"T Bassett","year":"2008","journal-title":"Cancer letters"},{"issue":"2","key":"ref61","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/S0022-5347(05)63959-6","article-title":"The prevalence of men with National Institutes of Health category IV prostatitis and association with serum prostate specific antigen","volume":"169","author":"BS Carver","year":"2003","journal-title":"The Journal of urology"},{"issue":"3","key":"ref62","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1007\/s11255-006-9125-2","article-title":"The correlation between serum prostate specific antigen levels and asymptomatic inflammatory prostatitis","volume":"39","author":"C Ozden","year":"2007","journal-title":"International urology and nephrology"},{"issue":"15","key":"ref63","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1002\/pros.21387","article-title":"Biomarkers for the diagnosis of prostatic inflammation in benign prostatic hyperplasia","volume":"71","author":"G Robert","year":"2011","journal-title":"The Prostate"},{"issue":"3","key":"ref64","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.urolonc.2005.11.033","article-title":"Cancer immunomics: using autoantibody signatures in the early detection of prostate cancer","volume":"24","author":"TJ Bradford","year":"2006","journal-title":"Urologic oncology"},{"issue":"5","key":"ref65","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1023\/B:JOCI.0000040920.96065.5a","article-title":"Identification of antigen-specific IgG in sera from patients with chronic prostatitis","volume":"24","author":"EJ Dunphy","year":"2004","journal-title":"Journal of clinical immunology"},{"issue":"1","key":"ref66","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s11255-005-1662-6","article-title":"Effects of chronic bacterial prostatitis on prostate specific antigen levels total and free in patients with benign prostatic hyperplasia and prostate cancer","volume":"38","author":"MN Battikhi","year":"2006","journal-title":"International urology and nephrology"},{"issue":"1","key":"ref67","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/MOU.0b013e32835abd4a","article-title":"Correlation between benign prostatic hyperplasia and inflammation","volume":"23","author":"Y Bostanci","year":"2013","journal-title":"Current opinion in urology"},{"issue":"2","key":"ref68","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/pros.2990250206","article-title":"Relationship between serum prostate specific antigen and histological prostatitis in patients with benign prostatic hyperplasia","volume":"25","author":"Y Hasui","year":"1994","journal-title":"The Prostate"},{"issue":"10","key":"ref69","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.7150\/ijms.6126","article-title":"Can mean platelet volume serve as a marker for prostatitis?","volume":"10","author":"H Karaman","year":"2013","journal-title":"International journal of medical sciences"},{"issue":"2","key":"ref70","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/pros.21229","article-title":"Antibody responses to prostate-associated antigens in patients with prostatitis and prostate cancer","volume":"71","author":"BB Maricque","year":"2011","journal-title":"The Prostate"},{"issue":"4","key":"ref71","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/pros.21071","article-title":"Leukocytic promotion of prostate cellular proliferation","volume":"70","author":"KL McDowell","year":"2010","journal-title":"The Prostate"},{"issue":"2","key":"ref72","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/pros.20862","article-title":"Inflammatory processes of prostate tissue microenvironment drive rat prostate carcinogenesis: preventive effects of celecoxib","volume":"69","author":"NK Narayanan","year":"2009","journal-title":"The Prostate"},{"issue":"7","key":"ref73","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1093\/carcin\/bgh317","article-title":"Prostate carcinogenesis and inflammation: emerging insights","volume":"26","author":"GS Palapattu","year":"2005","journal-title":"Carcinogenesis"},{"issue":"14","key":"ref74","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1002\/pros.20496","article-title":"A comprehensive association study for genes in inflammation pathway provides support for their roles in prostate cancer risk in the CAPS study","volume":"66","author":"SL Zheng","year":"2006","journal-title":"The Prostate"},{"issue":"12","key":"ref75","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1007\/s00262-009-0658-y","article-title":"Polymorphisms of pro-inflammatory genes and prostate cancer risk: a pharmacogenomic approach","volume":"58","author":"C Caruso","year":"2009","journal-title":"Cancer immunology, immunotherapy: CII"},{"key":"ref76","article-title":"Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer","author":"G Schaefer","year":"2013","journal-title":"Prostate cancer and prostatic diseases"},{"issue":"17","key":"ref77","doi-asserted-by":"crossref","first-page":"6997","DOI":"10.1073\/pnas.1304502110","article-title":"Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover","volume":"110","author":"C Geng","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"ref78","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.3390\/molecules17032474","article-title":"Fluorescence-based multiplex protein detection using optically encoded microbeads","volume":"17","author":"BH Jun","year":"2012","journal-title":"Molecules"},{"issue":"46","key":"ref79","doi-asserted-by":"crossref","first-page":"42938","DOI":"10.1074\/jbc.M101968200","article-title":"CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation","volume":"276","author":"J Jiang","year":"2001","journal-title":"The Journal of biological chemistry"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0147739","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,3]],"date-time":"2022-06-03T21:45:15Z","timestamp":1654292715000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0147739"}},"subtitle":[],"editor":[{"given":"Aamir","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,2,10]]},"references-count":79,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016,2,10]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0147739","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,10]]}}}