{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,3]],"date-time":"2025-08-03T04:03:49Z","timestamp":1754193829401},"reference-count":30,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0148402","type":"journal-article","created":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T18:53:33Z","timestamp":1454352813000},"page":"e0148402","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["Effects of Incretin-Based Therapies on Neuro-Cardiovascular Dynamic Changes Induced by High Fat Diet in Rats"],"prefix":"10.1371","volume":"11","author":[{"given":"Silvio Rodrigues","family":"Marques-Neto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel Carvalho","family":"Castiglione","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aiza","family":"Pontes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dahienne Ferreira","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuelle Baptista","family":"Ferraz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Hamilton Matheus","family":"Nascimento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliete","family":"Bouskela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2016,2,1]]},"reference":[{"issue":"7245","key":"ref1","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/459340a","article-title":"Causes and control of excess body fat","volume":"459","author":"JM Friedman","year":"2009","journal-title":"Nature"},{"issue":"3","key":"ref2","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1161\/01.cir.0000441139.02102.80","article-title":"Heart Disease and Stroke Statistics\u20132014 Update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee","volume":"129","author":"AS Go","year":"2014","journal-title":"Circulation"},{"key":"ref3","unstructured":"World Health Organization Outbreak media centre [Internet]. Fact sheet N\u00b0. 317 [March 2013]. Cardiovascular diseases. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.who.int\/mediacentre\/factsheets\/fs317\/en\/\" xlink:type=\"simple\">http:\/\/www.who.int\/mediacentre\/factsheets\/fs317\/en\/<\/ext-link>. Accessed 6 August 2014."},{"key":"ref4","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/j.1467-789X.2011.00860.x","article-title":"Obesity\u2014an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential","volume":"12","author":"SS Torekov","year":"2011","journal-title":"Obs Rev"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1161\/CIRCRESAHA.114.301958","article-title":"Cardiovascular actions of incretin-based therapies","volume":"114","author":"JR Ussher","year":"2014","journal-title":"Circ Res"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1210\/jcem-68-2-374","article-title":"Estimates of in vivo insulin action in man: comparison of insulin tolerance tests with euglycemic and hyperglycemic glucose clamp studies","volume":"68","author":"E Bonora","year":"1989","journal-title":"J Clin Endocrinol Metab"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/apha.12056","article-title":"The blockade of angiotensin AT1 and aldosterone receptors protects rats from synthetic androgen-induced cardiac autonomic dysfunction","volume":"208","author":"SR Marques-Neto","year":"2013","journal-title":"Acta Physiol (Oxf)"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1038\/jcbfm.2011.196","article-title":"Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain","volume":"32","author":"AY Shih","year":"2012","journal-title":"J Cereb Blood Flow Metab"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1038\/nm.1868","article-title":"Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer&apos;s disease","volume":"14","author":"H Du","year":"2012","journal-title":"Nat Med"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1185\/03007990802418851","article-title":"Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study","volume":"24","author":"RA De Fronzo","year":"2008","journal-title":"Curr Med Res Opin"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/S0140-6736(10)60307-8","article-title":"Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial","volume":"375","author":"RE Pratley","year":"2010","journal-title":"Lancet"},{"key":"ref12","first-page":"108","article-title":"GLP-1-based strategies: A physiological analysis of differential mode of action","volume":"29","author":"R Burcelin","year":"2014","journal-title":"Physiology (Bethesda)"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"E808","DOI":"10.1152\/ajpendo.1996.271.5.E808","article-title":"Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-1","volume":"271","author":"H Nakabayashi","year":"1996","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"Suppl 3","key":"ref14","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1016\/S1262-3636(10)70468-7","article-title":"The gut-brain axis: a major glucoregulatory player","volume":"36","author":"R Burcelin","year":"2010","journal-title":"Diabetes Metab"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"R1001","DOI":"10.1152\/ajpregu.00523.2012","article-title":"Early effects of high fat diet on neurovascular function and focal ischemic brain injury","volume":"304","author":"W Li","year":"2013","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"ref16","first-page":"573","article-title":"Postprandial glucagon-like peptide-1 (GLP-1) response is positively associated with changes in neuronal activity of brain areas implicated in satiety and food intake regulation in humans","volume":"86","author":"P Pannacciulli","year":"2007","journal-title":"Neuroimage"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"883","DOI":"10.3171\/jns.1984.60.5.0883","article-title":"Cerebral circulation and metabolism","volume":"60","author":"BK Siesjo","year":"1984","journal-title":"J Neurosurg"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"20","DOI":"10.17925\/USE.2010.06.1.20","article-title":"Mitochondrial dysfunction in obesity and diabetes","volume":"6","author":"WI Sivitz","year":"2010","journal-title":"US Endocrinol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1152\/physrev.00017.2007","article-title":"Cardiac Remodeling in Obesity","volume":"88","author":"ED Abel","year":"2008","journal-title":"Physiol Rev"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"975","DOI":"10.2337\/db08-1193","article-title":"GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice","volume":"58","author":"MH Noyan-Ashraf","year":"2009","journal-title":"Diabetes"},{"key":"ref21","first-page":"268","article-title":"Human Cardiovascular Control","author":"LB Rowell","year":"1993"},{"issue":"1","key":"ref22","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1549-8719.2011.00130.x","article-title":"Microvascular dysfunction: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension","volume":"19","author":"MP De Boer","year":"2012","journal-title":"Microcirculation"},{"issue":"1","key":"ref23","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1161\/HYPERTENSIONAHA.107.089680","article-title":"Microvascular dysfunction: a potential pathophysiological role in the metabolic syndrome","volume":"50","author":"EH Sern\u00e9","year":"2007","journal-title":"Hypertension"},{"issue":"1","key":"ref24","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1743-7075-8-32","article-title":"Brazil nuts intake improves lipid profile, oxidative stress and microvascular function in obese adolescents: a randomized controlled trial","volume":"8","author":"PA Maranh\u00e3o","year":"2011","journal-title":"Nutr Metab (Lond)"},{"issue":"11","key":"ref25","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1007\/s00125-013-3016-8","article-title":"Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: a randomised controlled trial","volume":"56","author":"DH van Raalte","year":"2013","journal-title":"Diabetologia"},{"issue":"10","key":"ref26","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.2337\/diabetes.51.10.2944","article-title":"Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes","volume":"51","author":"DE Kelley","year":"2002","journal-title":"Diabetes"},{"issue":"9433","key":"ref27","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0140-6736(04)16815-3","article-title":"Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammation","volume":"364","author":"M Singer","year":"2004","journal-title":"Lancet"},{"issue":"14","key":"ref28","doi-asserted-by":"crossref","first-page":"R551","DOI":"10.1016\/j.cub.2006.06.054","article-title":"Mitochondria: more than just a powerhouse","volume":"16","author":"HM McBride","year":"2006","journal-title":"Curr Biol"},{"issue":"2","key":"ref29","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.bbrc.2013.09.086","article-title":"High glucose-induced mitochondrial respiration and reactive oxygen species in mouse cerebral pericytes is reversed by pharmacological inhibition of mitochondrial carbonic anhydrases: Implications for cerebral microvascular disease in diabetes","volume":"440","author":"GN Shah","year":"2013","journal-title":"Biochem Biophys Res Commun"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.redox.2015.09.005","article-title":"Reactive oxygen species and mitochondria: A nexus of cellular homeostasis","volume":"6","author":"J Dan Dunn","year":"2015","journal-title":"Redox Biol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0148402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T10:56:29Z","timestamp":1589021789000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0148402"}},"subtitle":[],"editor":[{"given":"Julie A.","family":"Chowen","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,2,1]]},"references-count":30,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016,2,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0148402","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,1]]}}}