{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:31:28Z","timestamp":1791268288942,"version":"4.1.0"},"reference-count":20,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2016,2,11]],"date-time":"2016-02-11T00:00:00Z","timestamp":1455148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0148996","type":"journal-article","created":{"date-parts":[[2016,2,11]],"date-time":"2016-02-11T13:33:55Z","timestamp":1455197635000},"page":"e0148996","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":24,"title":["Microtubule and Actin Interplay Drive Intracellular c-Src Trafficking"],"prefix":"10.1371","volume":"11","author":[{"given":"Christopher","family":"Arnette","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keyada","family":"Frye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Kaverina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,2,11]]},"reference":[{"issue":"6","key":"ref1","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nrc1366","article-title":"A renaissance for SRC","volume":"4","author":"TJ Yeatman","year":"2004","journal-title":"Nature reviews Cancer"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0092-8674(00)81683-9","article-title":"The hallmarks of cancer","volume":"100","author":"D Hanahan","year":"2000","journal-title":"Cell"},{"issue":"6","key":"ref3","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.4049\/jimmunol.169.6.2997","article-title":"TCR signals mediated by Src family kinases are essential for the survival of naive T cells","volume":"169","author":"B Seddon","year":"2002","journal-title":"Journal of immunology"},{"issue":"20","key":"ref4","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1038\/onc.2009.77","article-title":"Redox regulation of anoikis resistance of metastatic prostate cancer cells: key role for Src and EGFR-mediated pro-survival signals","volume":"28","author":"E Giannoni","year":"2009","journal-title":"Oncogene"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1038\/ncomms2413","article-title":"Src activation by beta-adrenoreceptors is a key switch for tumour metastasis","volume":"4","author":"GN Armaiz-Pena","year":"2013","journal-title":"Nature communications"},{"issue":"8","key":"ref6","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1002\/cncr.22215","article-title":"The role of Src in solid and hematologic malignancies: development of new-generation Src inhibitors","volume":"107","author":"RH Alvarez","year":"2006","journal-title":"Cancer"},{"issue":"49","key":"ref7","doi-asserted-by":"crossref","first-page":"5620","DOI":"10.1038\/sj.onc.1203923","article-title":"Selected glimpses into the activation and function of Src kinase","volume":"19","author":"JD Bjorge","year":"2000","journal-title":"Oncogene"},{"issue":"2","key":"ref8","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1083\/jcb.118.2.321","article-title":"Association of p60c-src with endosomal membranes in mammalian fibroblasts","volume":"118","author":"KB Kaplan","year":"1992","journal-title":"The Journal of cell biology"},{"issue":"23","key":"ref9","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1016\/S0960-9822(01)00583-8","article-title":"Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity","volume":"11","author":"P Timpson","year":"2001","journal-title":"Current biology: CB"},{"issue":"11","key":"ref10","doi-asserted-by":"crossref","first-page":"4611","DOI":"10.1091\/mbc.E08-06-0603","article-title":"Microtubule-mediated Src tyrosine kinase trafficking in neuronal growth cones","volume":"19","author":"B Wu","year":"2008","journal-title":"Molecular biology of the cell"},{"issue":"13","key":"ref11","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.cub.2004.06.049","article-title":"Microtubule dynamics are necessary for SRC family kinase-dependent growth cone steering","volume":"14","author":"DM Suter","year":"2004","journal-title":"Current biology: CB"},{"issue":"6","key":"ref12","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.devcel.2004.09.019","article-title":"RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane","volume":"7","author":"E Sandilands","year":"2004","journal-title":"Developmental cell"},{"issue":"Pt 15","key":"ref13","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1242\/jcs.003657","article-title":"The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB\/RhoD endosome requirements","volume":"120","author":"E Sandilands","year":"2007","journal-title":"Journal of cell science"},{"issue":"2","key":"ref14","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.molonc.2013.11.001","article-title":"RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner","volume":"8","author":"D Luis-Ravelo","year":"2014","journal-title":"Molecular oncology"},{"issue":"12","key":"ref15","doi-asserted-by":"crossref","first-page":"e116252","DOI":"10.1371\/journal.pone.0116252","article-title":"Activation of the RhoB signaling pathway by thyroid hormone receptor beta in thyroid cancer cells","volume":"9","author":"S Ichijo","year":"2014","journal-title":"PloS one"},{"issue":"4","key":"ref16","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/ncb773","article-title":"Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton","volume":"4","author":"M Krendel","year":"2002","journal-title":"Nat Cell Biol"},{"issue":"5","key":"ref17","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1091\/mbc.E07-12-1269","article-title":"GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA","volume":"19","author":"YC Chang","year":"2008","journal-title":"Molecular biology of the cell"},{"issue":"5","key":"ref18","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.devcel.2007.03.014","article-title":"GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases","volume":"12","author":"J Birkenfeld","year":"2007","journal-title":"Developmental cell"},{"issue":"17","key":"ref19","doi-asserted-by":"crossref","first-page":"4108","DOI":"10.1038\/sj.emboj.7601286","article-title":"TRIF-GEFH1-RhoB pathway is involved in MHCII expression on dendritic cells that is critical for CD4 T-cell activation","volume":"25","author":"H Kamon","year":"2006","journal-title":"The EMBO journal"},{"issue":"5","key":"ref20","doi-asserted-by":"crossref","first-page":"120076","DOI":"10.1098\/rsob.120076","article-title":"RhoB regulates cell migration through altered focal adhesion dynamics","volume":"2","author":"FM Vega","year":"2012","journal-title":"Open biology"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0148996","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T21:56:14Z","timestamp":1540331774000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0148996"}},"subtitle":[],"editor":[{"given":"Neil A.","family":"Hotchin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,2,11]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016,2,11]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0148996","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,11]]}}}