{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T23:41:46Z","timestamp":1773272506021,"version":"3.50.1"},"reference-count":82,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0149300","type":"journal-article","created":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T19:02:44Z","timestamp":1456858964000},"page":"e0149300","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":18,"title":["Dietary Iodine Sufficiency and Moderate Insufficiency in the Lactating Mother and Nursing Infant: A Computational Perspective"],"prefix":"10.1371","volume":"11","author":[{"given":"W.","family":"Fisher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nysia I.","family":"George","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffery M.","family":"Gearhart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva D.","family":"McLanahan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2016,3,1]]},"reference":[{"issue":"5","key":"ref1","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1089\/thy.2008.0341","article-title":"Delayed neurobehavioral development in children born to pregnant women with mild hypothyroxinemia during the first month of gestation: the importance of early iodine supplementation","volume":"19","author":"P Berbel","year":"2009","journal-title":"Thyroid"},{"issue":"3","key":"ref2","first-page":"187","article-title":"Iodine Supplementation throughout Pregnancy Does Not Prevent the Drop in FT4 in the Second and Third Trimesters in Women with Normal Initial Thyroid Function","volume":"2","author":"F Brucker-Davis","year":"2013","journal-title":"Eur Thyroid J"},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/cen.12227","article-title":"Maternal hypothyroxinemia and effects on cognitive functioning in childhood: how and why?","volume":"79","author":"J Henrichs","year":"2013","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"1","key":"ref4","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1542\/peds.2005-0227","article-title":"Neonatal effects of maternal hypothyroxinemia during early pregnancy","volume":"117","author":"L Kooistra","year":"2006","journal-title":"Pediatrics"},{"issue":"6","key":"ref5","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1111\/j.1365-2265.2009.03743.x","article-title":"Abnormalities of maternal thyroid function during pregnancy affect neuropsychological development of their children at 25\u201330 months","volume":"72","author":"Y Li","year":"2010","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1002\/ana.23976","article-title":"Association of gestational maternal hypothyroxinemia and increased autism risk","volume":"74","author":"GC Roman","year":"2013","journal-title":"Ann Neurol"},{"key":"ref7","article-title":"Maternal Hypothyroxinemia-Induced Neurodevelopmental Impairments in the Progeny","author":"H Min","year":"2015","journal-title":"Mol Neurobiol"},{"issue":"2","key":"ref8","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1093\/toxsci\/kft078","article-title":"Evaluation of perturbations in serum thyroid hormones during human pregnancy due to dietary iodide and perchlorate exposure using a biologically based dose-response model","volume":"133","author":"A Lumen","year":"2013","journal-title":"Toxicol Sci"},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/AOG.0b013e3181788dd7","article-title":"Maternal thyroid hypofunction and pregnancy outcome","volume":"112","author":"J Cleary-Goldman","year":"2008","journal-title":"Obstet Gynecol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"463029","DOI":"10.4061\/2011\/463029","article-title":"Doubts and Concerns about Isolated Maternal Hypothyroxinemia","volume":"2011","author":"M Moleti","year":"2011","journal-title":"J Thyroid Res"},{"issue":"9","key":"ref11","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1515\/jpem.2010.145","article-title":"Serum thyroid hormone levels in preterm infants born before 33 weeks of gestation and association of transient hypothyroxinemia with postnatal characteristics","volume":"23","author":"D Dilli","year":"2010","journal-title":"J Pediatr Endocrinol Metab"},{"issue":"Pt 1","key":"ref12","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1258\/acb.2010.010174","article-title":"The measurement, definition, aetiology and clinical consequences of neonatal transient hypothyroxinaemia","volume":"48","author":"F Williams","year":"2011","journal-title":"Ann Clin Biochem"},{"issue":"8","key":"ref13","doi-asserted-by":"crossref","first-page":"4599","DOI":"10.1210\/jc.2005-0214","article-title":"Transient hypothyroxinemia in preterm infants: the role of cord sera thyroid hormone levels adjusted for prenatal and intrapartum factors","volume":"90","author":"FL Williams","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"issue":"8","key":"ref14","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1753-4887.2001.tb05512.x","article-title":"Iodine in human milk: perspectives for infant health.","volume":"59","author":"RD Semba","year":"2001","journal-title":"Nutr Rev"},{"issue":"4","key":"ref15","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0946-672X(02)80047-5","article-title":"Iodine nutrition and breast feeding","volume":"16","author":"JG Dorea","year":"2002","journal-title":"J Trace Elem Med Biol"},{"issue":"9","key":"ref16","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1089\/thy.2012.0058","article-title":"Environmental perchlorate and thiocyanate exposures and infant serum thyroid function","volume":"22","author":"AM Leung","year":"2012","journal-title":"Thyroid"},{"key":"ref17","year":"2006"},{"issue":"8","key":"ref18","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1089\/thy.2014.0026","article-title":"No difference in urinary iodine concentrations between Boston-area breastfed and formula-fed infants","volume":"24","author":"JH Gordon","year":"2014","journal-title":"Thyroid"},{"issue":"1","key":"ref19","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/toxsci\/kfs336","article-title":"Evaluation of iodide deficiency in the lactating rat and pup using a biologically based dose-response model","volume":"132","author":"JW Fisher","year":"2013","journal-title":"Toxicol Sci"},{"issue":"5","key":"ref20","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1289\/ehp.0800111","article-title":"Competitive inhibition of thyroidal uptake of dietary iodide by perchlorate does not describe perturbations in rat serum total T4 and TSH","volume":"117","author":"ED McLanahan","year":"2009","journal-title":"Environ Health Perspect"},{"issue":"2","key":"ref21","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1093\/toxsci\/kfm312","article-title":"A biologically based dose-response model for dietary iodide and the hypothalamic-pituitary-thyroid axis in the adult rat: evaluation of iodide deficiency","volume":"102","author":"ED McLanahan","year":"2008","journal-title":"Toxicol Sci"},{"issue":"1","key":"ref22","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1093\/toxsci\/kfs335","article-title":"An animal model of marginal iodine deficiency during development: the thyroid axis and neurodevelopmental outcome","volume":"132","author":"ME Gilbert","year":"2013","journal-title":"Toxicol Sci"},{"issue":"9","key":"ref23","doi-asserted-by":"crossref","first-page":"3170","DOI":"10.1210\/jc.2012-1759","article-title":"Serum thyroid hormone levels in healthy children from birth to adulthood and in short children born small for gestational age","volume":"97","author":"AJ Lem","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"ref24","unstructured":"Centers for Disease Control and Prevention (CDC), National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Data Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Diseaes Control and Prevention; 2007\u20132012. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.cdc.gov\/nchs\/nhanes\/nhanes_questionnaires.htm\" xlink:type=\"simple\">http:\/\/www.cdc.gov\/nchs\/nhanes\/nhanes_questionnaires.htm<\/ext-link>."},{"issue":"1","key":"ref25","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1210\/jcem-47-1-189","article-title":"Serum 3,5,3&apos;-triiodothyronine, thyroxine, and thyrotropin in hypothyroid infants with congenital goiter and the response to iodine","volume":"47","author":"P Heidemann","year":"1978","journal-title":"J Clin Endocrinol Metab"},{"key":"ref26","first-page":"195","article-title":"The Physiological Changes in Thyroid Function during Pregnancy","volume":"27","author":"SA Aboul-Khair","year":"1964","journal-title":"Clin Sci"},{"key":"ref27","unstructured":"Centers for Disease Control and Prevention (CDC), National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Data Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Diseaes Control and Prevention; 2009\u20132012. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.cdc.gov\/nchs\/nhanes\/nhanes_questionnaires.htm\" xlink:type=\"simple\">http:\/\/www.cdc.gov\/nchs\/nhanes\/nhanes_questionnaires.htm<\/ext-link>."},{"issue":"6","key":"ref28","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1469-7580.2005.00417.x","article-title":"Anatomy of the lactating human breast redefined with ultrasound imaging","volume":"206","author":"DT Ramsay","year":"2005","journal-title":"J Anat"},{"issue":"2","key":"ref29","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0940-9602(02)80016-4","article-title":"Quantification of glands and fat in breast tissue: an experimental determination","volume":"184","author":"E Vandeweyer","year":"2002","journal-title":"Ann Anat"},{"issue":"9","key":"ref30","first-page":"677","article-title":"Comparison of the whole breast target volume delineated according to surface marks, palpation and glandular tissue on CT images after breast-conserving surgery","volume":"36","author":"M Xu","year":"2014","journal-title":"Zhonghua Zhong Liu Za Zhi"},{"issue":"1","key":"ref31","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1113\/expphysiol.1992.sp003584","article-title":"The determination of short-term breast volume changes and the rate of synthesis of human milk using computerized breast measurement","volume":"77","author":"SE Daly","year":"1992","journal-title":"Exp Physiol"},{"issue":"6","key":"ref32","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1542\/peds.87.6.829","article-title":"Maternal versus infant factors related to breast milk intake and residual milk volume: the DARLING study","volume":"87","author":"KG Dewey","year":"1991","journal-title":"Pediatrics"},{"issue":"3","key":"ref33","doi-asserted-by":"crossref","first-page":"e387","DOI":"10.1542\/peds.2005-1417","article-title":"Volume and frequency of breastfeedings and fat content of breast milk throughout the day","volume":"117","author":"JC Kent","year":"2006","journal-title":"Pediatrics"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1186\/1471-2407-14-303","article-title":"Sodium iodide symporter (NIS) in extrathyroidal malignancies: focus on breast and urological cancer","volume":"14","author":"S Micali","year":"2014","journal-title":"BMC Cancer"},{"issue":"5","key":"ref35","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1210\/jc.2006-2738","article-title":"Breast milk iodine and perchlorate concentrations in lactating Boston-area women","volume":"92","author":"EN Pearce","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"ref36","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1080\/15287390600755216","article-title":"Perchlorate and radioiodide kinetics across life stages in the human: using PBPK models to predict dosimetry and thyroid inhibition and sensitive subpopulations based on developmental stage","volume":"70","author":"RA Clewell","year":"2007","journal-title":"J Toxicol Environ Health A"},{"issue":"9","key":"ref37","first-page":"933","article-title":"Nutrient intake by breast-fed infants during the first five days after birth","volume":"140","author":"CE Casey","year":"1986","journal-title":"Am J Dis Child"},{"issue":"6","key":"ref38","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1111\/j.1651-2227.1982.tb09555.x","article-title":"The amount of milk consumed by 1\u20133 months old breast- or bottle-fed infants","volume":"71","author":"Y Hofvander","year":"1982","journal-title":"Acta Paediatr Scand"},{"issue":"2","key":"ref39","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/risa.12101","article-title":"The use of PBPK models to inform human health risk assessment: case study on perchlorate and radioiodide human lifestage models","volume":"34","author":"ED McLanahan","year":"2014","journal-title":"Risk Anal"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0022-3476(41)80232-7","article-title":"The blood volume in normal infants and children","volume":"18","author":"JK Brines","year":"1941","journal-title":"J Pediatr"},{"issue":"3","key":"ref41","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1097\/00004032-199703000-00004","article-title":"A statistical analysis of the internal organ weights of normal Japanese people","volume":"72","author":"N Ogiu","year":"1997","journal-title":"Health Phys"},{"issue":"6","key":"ref42","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1016\/S0022-5347(05)65594-2","article-title":"Bladder function in healthy neonates and its development during infancy","volume":"166","author":"U Sillen","year":"2001","journal-title":"J Urol"},{"issue":"10","key":"ref43","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.2165\/00003088-200645100-00005","article-title":"Development and evaluation of a generic physiologically based pharmacokinetic model for children","volume":"45","author":"AN Edginton","year":"2006","journal-title":"Clin Pharmacokinet"},{"issue":"1","key":"ref44","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/toxsci\/kfi017","article-title":"PBPK model for radioactive iodide and perchlorate kinetics and perchlorate-induced inhibition of iodide uptake in humans","volume":"83","author":"EA Merrill","year":"2005","journal-title":"Toxicol Sci"},{"issue":"12","key":"ref45","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1210\/jcem-26-12-1392","article-title":"Iodide kinetic studies in newborns and infants","volume":"26","author":"G Ponchon","year":"1966","journal-title":"J Clin Endocrinol Metab"},{"issue":"12","key":"ref46","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1089\/thy.1998.8.1185","article-title":"Screening for congenital hypothyroidism used as an indicator of the degree of iodine deficiency and of its control","volume":"8","author":"F Delange","year":"1998","journal-title":"Thyroid"},{"key":"ref47","first-page":"595","article-title":"Simultane radioimmunologische bestimmung von thyroxin (T4) and trijodthronin (T3) im urin","volume":"14","author":"J Habermann","year":"1976","journal-title":"J Clin Chem Clin Biochem"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1210\/jcem-24-7-628","article-title":"Whole-Body Counting of I-131-Labeled Thyroxine","volume":"24","author":"TH Oddie","year":"1964","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"ref49","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1046\/j.1365-2265.2002.01526.x","article-title":"The quantity of thyroid hormone in human milk is too low to influence plasma thyroid hormone levels in the very preterm infant","volume":"56","author":"AG van Wassenaer","year":"2002","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1210\/jcem-23-8-811","article-title":"Thyroxine Secretion Rate during Infancy: Effect of Estrogen","volume":"23","author":"DA Fisher","year":"1963","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"ref51","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1093\/clinchem\/42.1.135","article-title":"Physiological variations in thyroid hormones: physiological and pathophysiological considerations","volume":"42","author":"DA Fisher","year":"1996","journal-title":"Clin Chem"},{"key":"ref52","first-page":"471","article-title":"Investigations on the metabolism of the thyroid hormone in children by means of radiothyroxine","volume":"3","author":"F Cottino","year":"1961","journal-title":"Panminerva Medica"},{"issue":"2\u20133","key":"ref53","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0028-2243(90)90159-X","article-title":"Changes in thyroid status in newborn infants utero-exposed to ritodrine","volume":"35","author":"M Gemelli","year":"1990","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"6","key":"ref54","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1172\/JCI108030","article-title":"Circulating 3,3&apos;, 5&apos;-triiodothyronine (reverse T3) in the human newborn","volume":"55","author":"IJ Chopra","year":"1975","journal-title":"J Clin Invest"},{"issue":"8","key":"ref55","first-page":"2868","article-title":"Ontogeny of iodothyronine deiodinases in human liver","volume":"83","author":"K Richard","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"ref56","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1210\/jcem-26-4-425","article-title":"Jr., Fisher DA. An analysis of published data on thyroxine turnover in human subjects","volume":"26","author":"TH Oddie","year":"1966","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"ref57","doi-asserted-by":"crossref","first-page":"323","DOI":"10.3109\/10408444.2012.674100","article-title":"Ontogeny of mammalian metabolizing enzymes in humans and animals used in toxicological studies","volume":"42","author":"SA Saghir","year":"2012","journal-title":"Crit Rev Toxicol"},{"issue":"9","key":"ref58","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1289\/ehp.0901736","article-title":"Goitrogenic anions, thyroid-stimulating hormone, and thyroid hormone in infants","volume":"118","author":"Y Cao","year":"2010","journal-title":"Environ Health Perspect"},{"issue":"10","key":"ref59","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1515\/CCLM.2001.158","article-title":"Reference intervals from birth to adulthood for serum thyroxine (T4), triiodothyronine (T3), free T3, free T4, thyroxine binding globulin (TBG) and thyrotropin (TSH)","volume":"39","author":"MW Elmlinger","year":"2001","journal-title":"Clin Chem Lab Med"},{"issue":"6","key":"ref60","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1055\/s-0031-1275326","article-title":"Reference ranges for analytes of thyroid function in children","volume":"43","author":"FA Verburg","year":"2011","journal-title":"Horm Metab Res"},{"issue":"2","key":"ref61","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1136\/adc.60.2.141","article-title":"Neonatal thyroid function: influence of perinatal factors","volume":"60","author":"RC Franklin","year":"1985","journal-title":"Arch Dis Child"},{"issue":"11","key":"ref62","doi-asserted-by":"crossref","first-page":"5314","DOI":"10.1210\/jc.2004-0869","article-title":"Developmental trends in cord and postpartum serum thyroid hormones in preterm infants","volume":"89","author":"FL Williams","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"ref63","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1089\/thy.2008.0249","article-title":"Iodine status of pregnant women and their progeny in the Minho Region of Portugal","volume":"19","author":"MJ Costeira","year":"2009","journal-title":"Thyroid"},{"issue":"9","key":"ref64","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1089\/thy.2009.0356","article-title":"Parameters of thyroid function throughout and after pregnancy in an iodine-deficient population","volume":"20","author":"MJ Costeira","year":"2010","journal-title":"Thyroid"},{"issue":"5","key":"ref65","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1530\/EJE-12-0759","article-title":"Thyroglobulin in smoking mothers and their newborns at delivery suggests autoregulation of placental iodide transport overcoming thiocyanate inhibition","volume":"168","author":"SL Andersen","year":"2013","journal-title":"Eur J Endocrinol"},{"issue":"5","key":"ref66","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/sj.ejcn.1600992","article-title":"Changes in iodine metabolism during late pregnancy and lactation: a longitudinal study among Sudanese women","volume":"54","author":"A Eltom","year":"2000","journal-title":"Eur J Clin Nutr"},{"issue":"1","key":"ref67","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s12011-008-8221-9","article-title":"Maternal milk concentration of zinc, iron, selenium, and iodine and its relationship to dietary intakes","volume":"127","author":"MA Hannan","year":"2009","journal-title":"Biol Trace Elem Res"},{"issue":"3","key":"ref68","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S2213-8587(13)70155-4","article-title":"Direct iodine supplementation of infants versus supplementation of their breastfeeding mothers: a double-blind, randomised, placebo-controlled trial","volume":"2","author":"RR Bouhouch","year":"2014","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"4","key":"ref69","doi-asserted-by":"crossref","first-page":"849","DOI":"10.3945\/ajcn.2010.29630","article-title":"Breast-milk iodine concentration declines over the first 6 mo postpartum in iodine-deficient women","volume":"92","author":"HM Mulrine","year":"2010","journal-title":"Am J Clin Nutr"},{"issue":"4","key":"ref70","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1539-6924.1994.tb00268.x","article-title":"Sensitivity of physiologically based pharmacokinetic models to variation in model parameters: methylene chloride","volume":"14","author":"HJ Clewell 3rd","year":"1994","journal-title":"Risk Anal"},{"issue":"5","key":"ref71","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1097\/FTD.0b013e31815709ac","article-title":"Gestation-specific thyroxine and thyroid stimulating hormone levels in the United States and worldwide","volume":"29","author":"OP Soldin","year":"2007","journal-title":"Ther Drug Monit"},{"key":"ref72","unstructured":"World Health Organization (WHO), United Nations Children&apos;s Fund (UNICEF), International Council for the Control of Iodine Deficiency Disorders (ICCIDD). Assessment of iodine deficiency disorders and monitoring their elimination. A guide for programme managers. 3 ed. Geneva: World Health Organization; 2007."},{"issue":"4","key":"ref73","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1089\/thy.2010.0077","article-title":"Iodine status of the U.S. population, National Health and Nutrition Examination Survey, 2005\u20132006 and 2007\u20132008","volume":"21","author":"KL Caldwell","year":"2011","journal-title":"Thyroid"},{"issue":"8","key":"ref74","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1089\/thy.2013.0012","article-title":"Iodine status in pregnant women in the National Children&apos;s Study and in U.S. women (15\u201344 years), National Health and Nutrition Examination Survey 2005\u20132010","volume":"23","author":"KL Caldwell","year":"2013","journal-title":"Thyroid"},{"issue":"6","key":"ref75","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1542\/peds.2014-0900","article-title":"Iodine deficiency, pollutant chemicals, and the thyroid: new information on an old problem","volume":"133","author":"WJ Rogan","year":"2014","journal-title":"Pediatrics"},{"issue":"4","key":"ref76","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1017\/S0007114507842292","article-title":"Reliability of studies of iodine intake and recommendations for number of samples in groups and in individuals","volume":"99","author":"S Andersen","year":"2008","journal-title":"Br J Nutr"},{"issue":"6","key":"ref77","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/sj.jes.7500648","article-title":"US Food and Drug Administration&apos;s Total Diet Study: dietary intake of perchlorate and iodine","volume":"18","author":"CW Murray","year":"2008","journal-title":"J Expo Sci Environ Epidemiol"},{"issue":"10","key":"ref78","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1507\/endocrj.EJ15-0382","article-title":"Standardization of FT4 and harmonization of TSH measurements\u2014a request for input from endocrinologists and other physicians","volume":"62","author":"LM Thienpont","year":"2015","journal-title":"Endocr J"},{"issue":"2","key":"ref79","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF03348681","article-title":"Enhanced iodine concentrating capacity by the mammary gland in iodine deficient lactating women of an endemic goiter region in Sicily","volume":"15","author":"F Vermiglio","year":"1992","journal-title":"J Endocrinol Invest"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.mce.2015.05.026","article-title":"Effect of hypothyroidism on the expression of nuclear receptors and their co-regulators in mammary gland during lactation in the rat","volume":"412","author":"F Campo","year":"2015","journal-title":"Mol Cell Endocrinol"},{"issue":"6","key":"ref81","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1203\/00006450-198306000-00008","article-title":"Thyroid hormones in human milk and their influence on thyroid function of breast-fed babies","volume":"17","author":"H Mizuta","year":"1983","journal-title":"Pediatr Res"},{"issue":"3\u20134","key":"ref82","first-page":"219","article-title":"Thyroid hormones in milk: physiological approach\u2014a review","volume":"17","author":"V Strbak","year":"1983","journal-title":"Endocrinol Exp"}],"updated-by":[{"DOI":"10.1371\/journal.pone.0155169","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2016,5,3]],"date-time":"2016-05-03T00:00:00Z","timestamp":1462233600000}}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0149300","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,5]],"date-time":"2022-06-05T23:00:50Z","timestamp":1654470050000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0149300"}},"subtitle":[],"editor":[{"given":"Michelina","family":"Plateroti","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,3,1]]},"references-count":82,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,3,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0149300","relation":{"correction":[{"id-type":"doi","id":"10.1371\/journal.pone.0155169","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,1]]}}}