{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:36:03Z","timestamp":1789727763719,"version":"4.0.1"},"reference-count":40,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T00:00:00Z","timestamp":1456358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0149915","type":"journal-article","created":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T18:33:40Z","timestamp":1456425220000},"page":"e0149915","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":5,"title":["Bioelectric and Morphological Response of Liquid-Covered Human Airway Epithelial Calu-3 Cell Monolayer to Periodic Deposition of Colloidal 3-Mercaptopropionic-Acid Coated CdSe-CdS\/ZnS Core-Multishell Quantum Dots"],"prefix":"10.1371","volume":"11","author":[{"given":"Aizat","family":"Turdalieva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Solandt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nestan","family":"Shambetova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Blom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hjalmar","family":"Brismar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Zelenina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,2,25]]},"reference":[{"issue":"4","key":"ref1","doi-asserted-by":"crossref","first-page":"MR17","DOI":"10.1116\/1.2815690","article-title":"Nanomaterials and nanoparticles: Sources and toxicity","volume":"2","author":"C Buzea","year":"2007","journal-title":"Biointerphases"},{"issue":"2","key":"ref2","first-page":"105","article-title":"Effects of quantum dot labeling on endothelial progenitor cell function and viability","volume":"1","author":"M Moln\u00e1r","year":"2010","journal-title":"Cell Medicine, Part B of Cell Transplantation"},{"issue":"5","key":"ref3","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.nantod.2011.08.001","article-title":"Cellular toxicity of inorganic nanoparticles: Common aspects and guidelines for improved nanotoxicity evaluation","volume":"6","author":"SJ Soenen","year":"2011","journal-title":"Nano Today"},{"issue":"12","key":"ref4","doi-asserted-by":"crossref","first-page":"2850","DOI":"10.3390\/ma5122850","article-title":"The toxic effects and mechanisms of CuO and ZnO nanoparticles","volume":"5","author":"YN Chang","year":"2012","journal-title":"Materials"},{"issue":"6","key":"ref5","doi-asserted-by":"crossref","first-page":"4748","DOI":"10.1021\/nn204886b","article-title":"Comprehensive analysis of the effects of CdSe quantum dot size, surface charge, and functionalization on primary human lung cells","volume":"6","author":"A Nagy","year":"2012","journal-title":"ACS Nano"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1743-8977-6-14","article-title":"Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines","volume":"6","author":"S Lanone","year":"2009","journal-title":"Part Fibre Toxicol"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1477-3155-2-12","article-title":"Nanoparticles\u2014known and unknown health risks","volume":"2","author":"PH Hoet","year":"2004","journal-title":"J Nanobiotechnology"},{"issue":"10","key":"ref8","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.3109\/03639041003695113","article-title":"Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model","volume":"36","author":"M Haghi","year":"2010","journal-title":"Drug Dev Ind Pharm"},{"key":"ref9","first-page":"8","article-title":"Cultured human airway epithelial cells (Calu-3): A model of human respiratory function, structure, and inflammatory responses","author":"Y Zhu","year":"2010","journal-title":"Critical Care Research and Practice"},{"key":"ref10","first-page":"e50157","article-title":"Establishing a liquid-covered culture of polarized human airway epithelial Calu-3 cells to study host cell response to respiratory pathogens in vitro","volume":"72","author":"JL Harcourt","year":"2013","journal-title":"J Vis Exp"},{"issue":"1\u20132","key":"ref11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-5173(00)00452-X","article-title":"Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery","volume":"208","author":"KA Foster","year":"2000","journal-title":"Int J Pharm"},{"issue":"1","key":"ref12","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1080\/10611860290007504","article-title":"Permeability characteristics of calu-3 human bronchial epithelial cells: In vitro-in vivo correlation to predict lung absorption in rats","volume":"10","author":"NR Mathia","year":"2002","journal-title":"J Drug Target"},{"issue":"1\u20133","key":"ref13","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0168-3659(02)00356-5","article-title":"Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3","volume":"87","author":"BI Florea","year":"2003","journal-title":"J Controll Release"},{"issue":"2","key":"ref14","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1097\/01.PCC.0000154944.67042.4F","article-title":"Hyperoxia-induced changes in human airway epithelial cells: The protective effect of perflubron","volume":"6","author":"PB Babu","year":"2005","journal-title":"Pediatr Crit Care Med"},{"issue":"6","key":"ref15","doi-asserted-by":"crossref","first-page":"e66600","DOI":"10.1371\/journal.pone.0066600","article-title":"Response to rhinovirus infection by human airway epithelial cells and peripheral blood mononuclear cells in an in vitro two-chamber tissue culture system","volume":"8","author":"D Rajan","year":"2013","journal-title":"PLoS ONE"},{"issue":"pt 5","key":"ref16","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1242\/jcs.111.5.541","article-title":"Tight junctions","volume":"111","author":"MS Balda","year":"1998","journal-title":"J Cell Science"},{"issue":"4","key":"ref17","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.bbamem.2009.01.011","article-title":"Multifaceted role of Rho, Rac, Cdc42 and Ras in intercellular junctions, lessons from toxins","volume":"1788","author":"MR Popoff","year":"2009","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"ref18","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.toxlet.2005.07.005","article-title":"In vitro study of the pulmonary translocation of nanoparticles. A preliminary study","volume":"160","author":"J Geys","year":"2006","journal-title":"Toxicol Lett"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1007\/s11051-012-1069-0","article-title":"Comparative effects of metal oxide nanoparticles on human airway epithelial cells and macrophages","volume":"14","author":"BM Rotoli","year":"2012","journal-title":"J Nanopart Res"},{"issue":"1\u20132","key":"ref20","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1159\/000337601","article-title":"Functional effects of nanoparticle exposure on Calu-3 airway epithelial cells","volume":"29","author":"A Banga","year":"2012","journal-title":"Cell Physiol Biochem"},{"key":"ref21","unstructured":"<ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.lgcstandards-atcc.org\/Products\/All\/HTB-55.aspx\" xlink:type=\"simple\">www.lgcstandards-atcc.org\/Products\/All\/HTB-55.aspx<\/ext-link>"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"15","DOI":"10.14227\/DT180311P15","article-title":"Simulated biological fluids with possible application in dissolution testing","volume":"18","author":"MRC Marques","year":"2011","journal-title":"Dissolution Technologies"},{"issue":"9","key":"ref23","doi-asserted-by":"crossref","first-page":"4844","DOI":"10.1021\/jp311975h","article-title":"Blinking, flickering, and correlation in fluorescence of single colloidal CdSe quantum dots with different shells under different excitations","volume":"117","author":"L Li","year":"2013","journal-title":"J Phys Chem C"},{"issue":"11","key":"ref24","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1016\/j.yexcr.2010.02.008","article-title":"Hypoglycosylated E-cadherin promotes the assembly of tight junctions through the recruitment of PP2A to adherens junctions","volume":"316","author":"M Nita-Lazar","year":"2010","journal-title":"Exp Cell Res"},{"issue":"6097","key":"ref25","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1126\/science.1223012","article-title":"A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia","volume":"337","author":"B Button","year":"2012","journal-title":"Science"},{"issue":"8","key":"ref26","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1021\/cm302108j","article-title":"Chemical, structural, and quantitative analysis of the ligand shells of colloidal quantum dots","volume":"25","author":"AJ Morris-Cohen","year":"2013","journal-title":"Chem Mater"},{"issue":"3","key":"ref27","doi-asserted-by":"crossref","first-page":"37003","DOI":"10.1209\/0295-5075\/86\/37003","article-title":"Radiative and nonradiative recombination of photoexcited excitons in multi-shell-coated CdSe\/CdS\/ZnS quantum dots","volume":"86","author":"Y Fu","year":"2009","journal-title":"EuroPhysics Lett"},{"issue":"6","key":"ref28","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1139\/bcb-2014-0062","article-title":"Expression of polycystins and fibrocystin on primary cilia of lung cells","volume":"92","author":"Q Hu","year":"2014","journal-title":"Biochem Cell Biol"},{"issue":"1","key":"ref29","doi-asserted-by":"crossref","first-page":"015005","DOI":"10.1117\/1.3316378","article-title":"Use of optical tweezers to probe epithelial mechanosensation","volume":"15","author":"A Resnick","year":"2010","journal-title":"J Biomed Opt"},{"issue":"5","key":"ref30","doi-asserted-by":"crossref","first-page":"F1096","DOI":"10.1152\/ajprenal.00657.2009","article-title":"Mechanical properties of primary cilia regulate the response to fluid flow","volume":"298","author":"S Rydholm","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"issue":"6 Pt 1","key":"ref31","first-page":"L1208","article-title":"Calcium-stimulated Cl<sup>\u2212<\/sup> secretion in Calu-3 human airway cells requires CFTR","volume":"273","author":"S Moon","year":"1997","journal-title":"Am J Physiol"},{"issue":"6","key":"ref32","doi-asserted-by":"crossref","first-page":"C1443","DOI":"10.1152\/ajpcell.00556.2007","article-title":"Apical adenosine regulates basolateral Ca<sup>2+<\/sup>-activated potassium channels in human airway Calu-3 epithelial cells","volume":"294","author":"D Wang","year":"2008","journal-title":"Am J Physiol Cell Physiol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.2147\/IJN.S21145","article-title":"Polystyrene nanoparticles activate ion transport in human airway epithelial cells","volume":"6","author":"J McCarthy","year":"2011","journal-title":"Int J Nanomedicine"},{"issue":"Suppl 1","key":"ref34","doi-asserted-by":"crossref","first-page":"216","DOI":"10.3109\/17435390.2013.879612","article-title":"Tracking translocation of industrially relevant engineered nanomaterials (ENMs) across alveolar epithelial monolayers in vitro","volume":"8","author":"JM Cohen","year":"2014","journal-title":"Nanotoxicology"},{"issue":"3","key":"ref35","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1164\/ajrccm\/137.3.726","article-title":"The propulsion of mucus by cilia","volume":"137","author":"MA Sleigh","year":"1988","journal-title":"Am. Rev. Respir. Dis"},{"issue":"2","key":"ref36","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1002\/cmmi.411","article-title":"Influence of cell-internalization on relaxometric, optical and compositional properties of targeted paramagnetic quantum dot micelles","volume":"6","author":"LWE Starmans","year":"2011","journal-title":"Contrast Media Mol Imaging"},{"issue":"9","key":"ref37","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1021\/acschembio.5b00434","article-title":"Rapid endolysosomal escape and controlled intracellular trafficking of cell surface mimetic quantum-dots-anchored peptides and glycopeptides","volume":"10","author":"RS Tan","year":"2015","journal-title":"ACS Chem Biol"},{"issue":"30","key":"ref38","doi-asserted-by":"crossref","first-page":"7616","DOI":"10.1016\/j.biomaterials.2011.06.046","article-title":"Visualizing the endocytic and exocytic processes of wheat germ agglutinin by quantum dot-based single-particle tracking","volume":"32","author":"SL Liu","year":"2011","journal-title":"Biomaterials"},{"issue":"7","key":"ref39","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1016\/j.bpj.2012.08.054","article-title":"3D single molecule tracking with multifocal plane microscopy reveals rapid intercellular transferrin transport at epithelial cell barriers","volume":"103","author":"S Ram","year":"2012","journal-title":"Biophys J"},{"issue":"11","key":"ref40","doi-asserted-by":"crossref","first-page":"6787","DOI":"10.1021\/nn101277w","article-title":"Endo- and exocytosis of zwitterionic quantum dot nanoparticles by live HeLa cells","volume":"4","author":"X Jiang","year":"2010","journal-title":"ACS Nano"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0149915","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,5]],"date-time":"2022-06-05T05:57:23Z","timestamp":1654408643000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0149915"}},"subtitle":[],"editor":[{"given":"Wei-Chun","family":"Chin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,2,25]]},"references-count":40,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016,2,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0149915","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,25]]}}}