{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:12:14Z","timestamp":1792541534216,"version":"4.5.0"},"reference-count":23,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2016,3,21]],"date-time":"2016-03-21T00:00:00Z","timestamp":1458518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0152132","type":"journal-article","created":{"date-parts":[[2016,3,21]],"date-time":"2016-03-21T17:35:13Z","timestamp":1458581713000},"page":"e0152132","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":68,"title":["Evaluation of Trimethoprim\/Sulfamethoxazole (SXT), Minocycline, Tigecycline, Moxifloxacin, and Ceftazidime Alone and in Combinations for SXT-Susceptible and SXT-Resistant Stenotrophomonas maltophilia by In Vitro Time-Kill Experiments"],"prefix":"10.1371","volume":"11","author":[{"given":"Chuanqi","family":"Wei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentao","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuejiu","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junchang","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,3,21]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/S1473-3099(09)70083-0","article-title":"<italic>Stenotrophomonas maltophilia<\/italic>: an emerging opportunist human pathogen","volume":"9","author":"W Looney","year":"2009","journal-title":"Lancet Infect Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.ijantimicag.2014.01.007","article-title":"Antimicrobial susceptibility of Gram-negative organisms isolated from patients hospitalised with pneumonia in US and European hospitals: results from the SENTRY Antimicrobial Surveillance Program, 2009\u20132012","volume":"43","author":"HS Sader","year":"2014","journal-title":"Int J Antimicrob Agents"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1128\/CMR.00019-11","article-title":"<italic>Stenotrophomonas maltophilia<\/italic>: an Emerging Global Opportunistic Pathogen","volume":"25","author":"Brooke Joanna S.","year":"2012","journal-title":"Clin. Microbiol. Rev"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1001\/archinte.1994.00420210028004","article-title":"Management of Adverse Reactions to Trimethoprim-Sulfamethoxazole in Human Immunodeficiency Virus-Infected Patients","volume":"154","author":"C Alan","year":"1994","journal-title":"Arch Intern Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1128\/CMR.11.1.57","article-title":"Microbiological and clinical aspects of infection caused by <italic>Stenotrophomonas maltophilia<\/italic>","volume":"11","author":"M Denton","year":"1998","journal-title":"Clin Microbiol Rev"},{"key":"ref6","first-page":"365","article-title":"Antibiotics in Laboratory Medicine","author":"S. K. Pillai","year":"2005"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ijantimicag.2014.10.002","article-title":"In vitro synergy of polymyxins with other antibiotics for Acinetobacter baumannii: a systematic review and meta-analysis","volume":"45","author":"W Ni","year":"2015","journal-title":"Int J Antimicrob Agents"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"3997","DOI":"10.1128\/AAC.46.12.3997-3999.2002","article-title":"In Vitro Killing Effect of Moxifloxacin on Clinical Isolates of Stenotrophomonas maltophilia Resistant to Trimethoprim-Sulfamethoxazole","volume":"46","author":"J Evangelos","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1128\/AAC.39.10.2220","article-title":"In Vitro Activities of Antimicrobial Combinations against Stenotrophomonas (Xanthomonas) maltophilia","volume":"39","author":"C D Poulos","year":"1995","journal-title":"Antimicrob Agents Chemother"},{"key":"ref10","unstructured":"Performance Standards for Antimicrobial Susceptibility Testing; <italic>Twenty-Fifth Informational Supplement<\/italic>. CLSI document M100-S25. Wayne, PA: Clinical and Laboratory Standards Institute, 2015."},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1128\/AAC.00741-13","article-title":"Evaluation of double- and triple-antibiotic combinations for VIM- and NDM-producing <italic>Klebsiella<\/italic> pneumoniae by in vitro time-kill experiments","volume":"58","author":"T T\u00e4ngd\u00e9n","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"ref12","unstructured":"Jay P. Sanford. <italic>The Sanford guide to antimicrobial therapy<\/italic> 43<sup>rd<\/sup> edition.p.86"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.diagmicrobio.2005.05.006","article-title":"Pharmacokinetic\/pharmacodynamic profile for tigecycline-a new glycylcycline antimicrobial agent","volume":"52","author":"AK Meagher","year":"2005","journal-title":"Diagn Microbiol Infect Dis"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"233S","DOI":"10.1592\/phco.21.16.233S.33992","article-title":"Pharmacokinetics and pharmacodynamics of fluoroquinolones","volume":"21","author":"KA Rodvold","year":"2001","journal-title":"Pharmacotherapy"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1128\/AAC.25.5.638","article-title":"Pharmacokinetics of ceftazidime in normal and uremic subjects","volume":"25","author":"A Leroy","year":"1984","journal-title":"Antimicrob Agents Chemother"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"4347","DOI":"10.1128\/AAC.00714-15","article-title":"The efflux pump SmeDEF contributes to trimethoprim-sulfamethoxazole resistance in <italic>Stenotrophomonas maltophilia<\/italic>","volume":"59","author":"MB S\u00e1nchez","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1093\/jac\/dkn301","article-title":"Therapeutic options for <italic>Stenotrophomonas maltophilia<\/italic> infections beyond co-trimoxazole: a systematic review","volume":"62","author":"ME Falagas","year":"2008","journal-title":"J Antimicrob Chemother"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"846","DOI":"10.3109\/23744235.2015.1064542","article-title":"A Monte-Carlo pharmacokinetic\/pharmacodynamic simulation to evaluate the efficacy of minocycline, tigecycline, moxifloxacin and levofloxacin in the treatment of hospital-acquired pneumonia caused by <italic>Stenotrophomonas maltophilia<\/italic>","volume":"47","author":"Chuanqi Wei","year":"2015","journal-title":"Infect Dis"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"S303","DOI":"10.1086\/431672","article-title":"Tigecycline: a new glycylcycline for treatment of serious infections","volume":"41","author":"GA Noskin","year":"2005","journal-title":"Clin Infect Dis"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.idc.2009.06.008","article-title":"Pharmacokinetics and pharmacodynamics of antibacterial agents","volume":"23","author":"ME Levison","year":"2009","journal-title":"Infect Dis Clin North Am"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1128\/AAC.01324-13","article-title":"Monotherapy with fluoroquinolone or trimethoprim-sulfamethoxazole for treatment of <italic>Stenotrophomonas maltophilia<\/italic> infections","volume":"58","author":"YL Wang","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"ref22","article-title":"Monotherapy with minocycline or trimethoprim\/sulfamethoxazole for treatment of <italic>Stenotrophomonas maltophilia<\/italic> infections","author":"E Hand","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.diagmicrobio.2004.09.002","article-title":"Antibiotic combinations significantly more active than monotherapy in an in vitro infection model of <italic>Stenotrophomonas maltophilia<\/italic>","volume":"51","author":"SA Zelenitsky","year":"2005","journal-title":"Diagn Microbiol Infect Dis"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0152132","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T06:27:27Z","timestamp":1589005647000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0152132"}},"subtitle":[],"editor":[{"given":"Andrew C","family":"Singer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,3,21]]},"references-count":23,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,3,21]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0152132","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,21]]}}}