{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:48:35Z","timestamp":1790700515357,"version":"4.1.0"},"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2016,3,30]],"date-time":"2016-03-30T00:00:00Z","timestamp":1459296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0152640","type":"journal-article","created":{"date-parts":[[2016,3,30]],"date-time":"2016-03-30T22:01:37Z","timestamp":1459375297000},"page":"e0152640","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":41,"title":["Streptococcus pyogenes Pneumonia in Adults: Clinical Presentation and Molecular Characterization of Isolates 2006-2015"],"prefix":"10.1371","volume":"11","author":[{"given":"Esther","family":"Tamayo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milagrosa","family":"Montes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Vicente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio","family":"P\u00e9rez-Trallero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,3,30]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/00000441-196108000-00003","article-title":"Beta hemolytic streptococcal pneumonia: report of an outbreak in a military population","volume":"242","author":"CC Welch","year":"1961","journal-title":"Am J Med Sci"},{"key":"ref2","first-page":"580","article-title":"Streptococcal pneumonia. Recent outbreaks in military recruit populations","volume":"44","author":"JL Basiliere","year":"1968","journal-title":"Am J Med"},{"issue":"37","key":"ref3","first-page":"1","article-title":"Pneumonia in the native mine labourers of northern Rhodesia copperfields with an account of an experiment in pneumonia prophylaxis by means of a vaccine at the Roan Antelope Mine","volume":"7","author":"D Ordman","year":"1935","journal-title":"Publ S Afr Inst Med Res"},{"issue":"17","key":"ref4","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1056\/NEJMra1312885","article-title":"Community-acquired pneumonia","volume":"371","author":"DM Musher","year":"2014","journal-title":"N Engl J Med"},{"key":"ref5","first-page":"101","article-title":"Community-Acquired pneumonia","author":"C Molina","year":"2001"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1093\/cid\/cis422","article-title":"Evolving epidemiologic characteristics of invasive group a streptococcal disease in Utah, 2002\u20132010","volume":"55","author":"C Stockmann","year":"2012","journal-title":"Clin Infect Dis"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1001\/archinte.163.4.467","article-title":"Clinical and epidemiologic features of group A streptococcal pneumonia in Ontario, Canada","volume":"163","author":"MP Muller","year":"2003","journal-title":"Arch Intern Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1007\/s100960050333","article-title":"Review of 17 cases of pneumonia caused by Streptococcus pyogenes","volume":"18","author":"M Barnham","year":"1999","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3201\/eid2001.130233","article-title":"Rapidly fatal hemorrhagic pneumonia and group a streptococcus serotype m1","volume":"20","author":"M Santagati","year":"2013","journal-title":"Emerg Infect Dis"},{"issue":"6","key":"ref10","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1378\/chest.129.6.1724","article-title":"A 48-year-old woman with pneumonia, shock, and a rash","volume":"129","author":"MD Siegel","year":"2006","journal-title":"Chest"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1440-1754.2004.00296.x","article-title":"Fatal necrotizing pneumonia caused by group A streptococcus","volume":"40","author":"AB Cengiz","year":"2004","journal-title":"J Paediatr Child Health"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1056\/NEJM199701233360402","article-title":"A prediction rule to identify low-risk patients with community-acquired pneumonia","volume":"336","author":"MJ Fine","year":"1997","journal-title":"N Engl J Med"},{"key":"ref13","unstructured":"Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Fifth Informational Supplement. CLSI document M100-S25. CLSI, Wayne, PA, USA, 2015."},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1128\/AAC.01054-06","article-title":"Phenotypic and genotypic characterisation of <italic>Streptococcus pyogenes<\/italic> isolates displaying the MLSB phenotype of macrolide resistance in Spain, 1999 to 2005","volume":"51","author":"E P\u00e9rez-Trallero","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.1128\/AAC.44.11.3196-3198.2000","article-title":"Resistance to multiple fluoroquinolones in a clinical isolate of <italic>Streptococcus pyogenes<\/italic>: identification of gyrA and parC and specification of point mutations associated with resistance","volume":"44","author":"SS Yan","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1007\/s10096-011-1226-x","article-title":"Epidemiological and molecular analysis of <italic>Streptococcus pyogenes<\/italic> isolates causing invasive disease in Spain (1998\u20132009): comparison with non-invasive isolates","volume":"30","author":"M Montes","year":"2011","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"5","DOI":"10.2807\/1560-7917.ES2014.19.17.20784","article-title":"Invasive infections due to Streptococcus pyogenes: seasonal variation of severity and clinical characteristics, Iceland,1975 to 2012","volume":"19","author":"LB Olafsdottir","year":"2014","journal-title":"Euro Surveill"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1086\/427502","article-title":"Pneumonia outbreak associated with group A Streptococcus species at a military training facility","volume":"40","author":"NF Crum","year":"2005","journal-title":"Clin Infect Dis"},{"key":"ref19","first-page":"337","article-title":"Respiratory Infections","author":"F Blasi","year":"2006"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1056\/NEJMoa1500245","article-title":"Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults","volume":"373","author":"S Jain","year":"2015","journal-title":"N Engl J Med"},{"issue":"9","key":"ref21","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1056\/NEJMoa1405870","article-title":"Community-acquired pneumonia requiring hospitalization among U.S. children","volume":"372","author":"S Jain","year":"2015","journal-title":"N Engl J Med"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"e1001444","DOI":"10.1371\/journal.pmed.1001444","article-title":"Carriage of Mycoplasma pneumoniae in the upper respiratory tract of symptomatic and asymptomatic children: an observational study","volume":"10","author":"EB Spuesens","year":"2013","journal-title":"PLoS Med"},{"issue":"9","key":"ref23","first-page":"683","article-title":"Community-acquired staphylococcal pneumonia","volume":"34","author":"JW Santos","year":"2008","journal-title":"J Bras Pneumol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.jcrc.2010.09.002","article-title":"Bacteremia in <italic>Staphylococcus aureus<\/italic> pneumonia: outcomes and epidemiology","volume":"26","author":"MP Schreiber","year":"2011","journal-title":"J Crit Care"},{"issue":"3","key":"ref25","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1001\/jama.2012.194139","article-title":"Bacterial coinfection in influenza: a grand rounds review","volume":"309","author":"DS Chertow","year":"2013","journal-title":"JAMA"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1086\/652291","article-title":"Invasive group A streptococcal infection concurrent with 2009 H1N1 influenza","volume":"50","author":"C Jean","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"5","key":"ref27","doi-asserted-by":"crossref","DOI":"10.2807\/ese.16.05.19780-en","article-title":"Group A streptococcal infections during the seasonal influenza outbreak 2010\/11 in South East England","volume":"16","author":"J Scaber","year":"2011","journal-title":"Euro Surveill"},{"issue":"11","key":"ref28","article-title":"Letter to the editor","volume":"16","author":"P Parola","year":"2011","journal-title":"Euro Surveill"},{"issue":"1","key":"ref29","doi-asserted-by":"crossref","first-page":"e61","DOI":"10.1542\/peds.112.1.e61","article-title":"A family cluster of five cases of group A streptococcal pneumonia","volume":"112","author":"S Roy","year":"2003","journal-title":"Pediatrics"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1056\/NEJM199608223350803","article-title":"Invasive group A streptococcal infections in Ontario, Canada. Ontario Group A Streptococcal Study Group","volume":"335","author":"HD Davies","year":"1996","journal-title":"N Engl J Med"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1073\/pnas.1403138111","article-title":"Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences","volume":"111","author":"W Nasser","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1128\/AAC.00780-09","article-title":"Prevalence and clonal characterisation of <italic>Streptococcus pyogenes<\/italic> clinical isolates with reduced fluoroquinolone susceptibility in Spain","volume":"54","author":"M Montes","year":"2010","journal-title":"Antimicrob Agents Chemother"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0152640","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T18:01:01Z","timestamp":1655402461000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0152640"}},"subtitle":[],"editor":[{"given":"Michael S.","family":"Chaussee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,3,30]]},"references-count":32,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,3,30]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0152640","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,30]]}}}