{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T01:59:20Z","timestamp":1762999160791},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T00:00:00Z","timestamp":1461801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funding for this research was provided by Bakken Research Center, Medtronic, Inc. Maastricht, The Netherlands."}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0154024","type":"journal-article","created":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T15:01:29Z","timestamp":1461855689000},"page":"e0154024","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":28,"title":["In Heart Failure Patients with Left Bundle Branch Block Single Lead MultiSpot Left Ventricular Pacing Does Not Improve Acute Hemodynamic Response To Conventional Biventricular Pacing. A Multicenter Prospective, Interventional, Non-Randomized Study"],"prefix":"10.1371","volume":"11","author":[{"given":"Maciej","family":"Sterli\u0144ski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Sokal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rados\u0142aw","family":"Lenarczyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederic","family":"Van Heuverswyn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Aldo","family":"Rinaldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Vanderheyden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Khalameizer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darrel","family":"Francis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joeri","family":"Heynens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berthold","family":"Stegemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Cornelussen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2016,4,28]]},"reference":[{"issue":"3","key":"ref1","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1253\/circj.CJ-10-1268","article-title":"Non-responders to cardiac resynchronization therapy: the magnitude of the problem and the issues","volume":"75","author":"A Auricchio","year":"2011","journal-title":"Circulation journal: official journal of the Japanese Circulation Society"},{"issue":"24","key":"ref2","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1056\/NEJMoa013168","article-title":"Cardiac resynchronization in chronic heart failure","volume":"346","author":"WT Abraham","year":"2002","journal-title":"The New England journal of medicine"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.hrthm.2013.10.018","article-title":"Acute electrical and hemodynamic effects of multisite left ventricular pacing for cardiac resynchronization therapy in the dyssynchronous canine heart","volume":"11","author":"S Ploux","year":"2014","journal-title":"Heart rhythm: the official journal of the Heart Rhythm Society"},{"issue":"5","key":"ref4","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.hrthm.2010.01.035","article-title":"Impact of segmental left ventricle lead position on cardiac resynchronization therapy outcomes","volume":"7","author":"FM Merchant","year":"2010","journal-title":"Heart rhythm: the official journal of the Heart Rhythm Society"},{"issue":"10","key":"ref5","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1046\/j.1540-8167.2004.04089.x","article-title":"Impact of coronary sinus lead position on biventricular pacing: mortality and echocardiographic evaluation during long-term follow-up","volume":"15","author":"A Rossillo","year":"2004","journal-title":"Journal of cardiovascular electrophysiology"},{"issue":"9","key":"ref6","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.cardfail.2010.04.010","article-title":"Addition of a second LV pacing site in CRT nonresponders rationale and design of the multicenter randomized V(3) trial","volume":"16","author":"P Bordachar","year":"2010","journal-title":"Journal of cardiac failure"},{"issue":"15","key":"ref7","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1016\/j.jacc.2007.11.074","article-title":"A randomized comparison of triple-site versus dual-site ventricular stimulation in patients with congestive heart failure","volume":"51","author":"C Leclercq","year":"2008","journal-title":"Journal of the American College of Cardiology"},{"issue":"1","key":"ref8","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1093\/europace\/euu197","article-title":"A review of multisite pacing to achieve cardiac resynchronization therapy","volume":"17","author":"CA Rinaldi","year":"2015","journal-title":"Europace: European pacing, arrhythmias, and cardiac electrophysiology: journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology"},{"issue":"6","key":"ref9","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1093\/europace\/eut420","article-title":"A comparison of left ventricular endocardial, multisite, and multipolar epicardial cardiac resynchronization: an acute haemodynamic and electroanatomical study","volume":"16","author":"AK Shetty","year":"2014","journal-title":"Europace: European pacing, arrhythmias, and cardiac electrophysiology: journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology"},{"issue":"5","key":"ref10","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/pace.12606","article-title":"Acute hemodynamic effects of single- and dual-site left ventricular pacing employing a dual cathodal coronary sinus lead","volume":"38","author":"BM van Gelder","year":"2015","journal-title":"Pacing and clinical electrophysiology: PACE"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/europace\/eur336","article-title":"Multi-site left ventricular pacing as a potential treatment for patients with postero-lateral scar: insights from cardiac magnetic resonance imaging and invasive haemodynamic assessment","volume":"14","author":"MR Ginks","year":"2012","journal-title":"Europace: European pacing, arrhythmias, and cardiac electrophysiology: journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology"},{"issue":"7","key":"ref12","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1093\/europace\/eus435","article-title":"Acute haemodynamic comparison of multisite and biventricular pacing with a quadripolar left ventricular lead","volume":"15","author":"B Thibault","year":"2013","journal-title":"Europace: European pacing, arrhythmias, and cardiac electrophysiology: journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology"},{"issue":"1","key":"ref13","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s10840-014-9891-1","article-title":"Improvement in acute contractility and hemodynamics with multipoint pacing via a left ventricular quadripolar pacing lead","volume":"40","author":"CA Rinaldi","year":"2014","journal-title":"Journal of interventional cardiac electrophysiology: an international journal of arrhythmias and pacing"},{"issue":"3","key":"ref14","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.hrthm.2013.11.023","article-title":"Multipoint left ventricular pacing improves acute hemodynamic response assessed with pressure-volume loops in cardiac resynchronization therapy patients","volume":"11","author":"C Pappone","year":"2014","journal-title":"Heart rhythm: the official journal of the Heart Rhythm Society"},{"issue":"5","key":"ref15","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.hrthm.2015.01.034","article-title":"Multipoint pacing by a left ventricular quadripolar lead improves the acute hemodynamic response to CRT compared with conventional biventricular pacing at any site","volume":"12","author":"F Zanon","year":"2015","journal-title":"Heart rhythm: the official journal of the Heart Rhythm Society"},{"issue":"11","key":"ref16","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1136\/hrt.2005.080721","article-title":"Haemodynamic effects of changes in atrioventricular and interventricular delay in cardiac resynchronisation therapy show a consistent pattern: analysis of shape, magnitude and relative importance of atrioventricular and interventricular delay","volume":"92","author":"ZI Whinnett","year":"2006","journal-title":"Heart"},{"issue":"11","key":"ref17","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.hrthm.2012.07.009","article-title":"Investigation of a novel algorithm for synchronized left-ventricular pacing and ambulatory optimization of cardiac resynchronization therapy: results of the adaptive CRT trial","volume":"9","author":"DO Martin","year":"2012","journal-title":"Heart rhythm: the official journal of the Heart Rhythm Society"},{"issue":"10","key":"ref18","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1093\/eurjhf\/hfr094","article-title":"Baseline left ventricular dP\/dtmax rather than the acute improvement in dP\/dtmax predicts clinical outcome in patients with cardiac resynchronization therapy","volume":"13","author":"MD Bogaard","year":"2011","journal-title":"European journal of heart failure"},{"issue":"2","key":"ref19","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1540-8159.2011.03268.x","article-title":"The acute hemodynamic response to LV pacing within individual branches of the coronary sinus using a quadripolar lead","volume":"35","author":"AK Shetty","year":"2012","journal-title":"Pacing and clinical electrophysiology: PACE"},{"issue":"12","key":"ref20","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1016\/j.hrthm.2015.07.012","article-title":"Mechanistic insights into the benefits of multisite pacing in cardiac resynchronization therapy: The importance of electrical substrate and rate of left ventricular activation","volume":"12","author":"M Sohal","year":"2015","journal-title":"Heart rhythm: the official journal of the Heart Rhythm Society"},{"issue":"12","key":"ref21","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1016\/j.amjcard.2008.08.016","article-title":"Dual-site left ventricular cardiac resynchronization therapy","volume":"102","author":"L Padeletti","year":"2008","journal-title":"The American journal of cardiology"},{"issue":"11","key":"ref22","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.cardfail.2013.10.003","article-title":"Acute effects of multisite left ventricular pacing on mechanical dyssynchrony in patients receiving cardiac resynchronization therapy","volume":"19","author":"CA Rinaldi","year":"2013","journal-title":"Journal of cardiac failure"},{"issue":"2","key":"ref23","doi-asserted-by":"crossref","first-page":"e48","DOI":"10.1111\/j.1540-8159.2011.03267.x","article-title":"Quad-site pacing using a quadripolar left ventricular pacing lead","volume":"36","author":"AK Shetty","year":"2013","journal-title":"Pacing and clinical electrophysiology: PACE"},{"issue":"6","key":"ref24","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1016\/j.hrthm.2015.02.008","article-title":"Improving cardiac resynchronization therapy response with multipoint left ventricular pacing: Twelve-month follow-up study","volume":"12","author":"C Pappone","year":"2015","journal-title":"Heart rhythm: the official journal of the Heart Rhythm Society"},{"issue":"3","key":"ref25","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.hrthm.2013.12.015","article-title":"Multipoint pacing: can we connect the dots to improve resynchronization therapy?","volume":"11","author":"C Gottlieb","year":"2014","journal-title":"Heart rhythm: the official journal of the Heart Rhythm Society"},{"issue":"2","key":"ref26","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1540-8159.2011.03243.x","article-title":"Biophysical modeling to simulate the response to multisite left ventricular stimulation using a quadripolar pacing lead","volume":"35","author":"SA Niederer","year":"2012","journal-title":"Pacing and clinical electrophysiology: PACE"},{"issue":"5","key":"ref27","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1161\/CIRCEP.111.967505","article-title":"Benefits of endocardial and multisite pacing are dependent on the type of left ventricular electric activation pattern and presence of ischemic heart disease: insights from electroanatomic mapping","volume":"5","author":"MR Ginks","year":"2012","journal-title":"Circulation Arrhythmia and electrophysiology"},{"issue":"3","key":"ref28","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1540-8159.2004.00433.x","article-title":"QRS duration and shortening to predict clinical response to cardiac resynchronization therapy in patients with end-stage heart failure","volume":"27","author":"SG Molhoek","year":"2004","journal-title":"Pacing and clinical electrophysiology: PACE"},{"issue":"12","key":"ref29","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1056\/NEJM200103223441202","article-title":"Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay","volume":"344","author":"S Cazeau","year":"2001","journal-title":"The New England journal of medicine"},{"issue":"2","key":"ref30","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1007\/s12265-015-9615-7","article-title":"Vectorcardiography for optimization of stimulation intervals in cardiac resynchronization therapy","volume":"8","author":"CJ van Deursen","year":"2015","journal-title":"Journal of cardiovascular translational research"},{"issue":"7","key":"ref31","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.hrthm.2013.03.009","article-title":"The effect of left ventricular electrical delay on AV optimization for cardiac resynchronization therapy","volume":"10","author":"MR Gold","year":"2013","journal-title":"Heart rhythm: the official journal of the Heart Rhythm Society"},{"issue":"3","key":"ref32","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1016\/j.ijcard.2013.01.216","article-title":"Comparison of different invasive hemodynamic methods for AV delay optimization in patients with cardiac resynchronization therapy: implications for clinical trial design and clinical practice","volume":"168","author":"ZI Whinnett","year":"2013","journal-title":"International journal of cardiology"},{"issue":"3","key":"ref33","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s10741-010-9203-5","article-title":"When is an optimization not an optimization? Evaluation of clinical implications of information content (signal-to-noise ratio) in optimization of cardiac resynchronization therapy, and how to measure and maximize it","volume":"16","author":"PA Pabari","year":"2011","journal-title":"Heart failure reviews"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0154024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T09:14:19Z","timestamp":1540026859000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0154024"}},"subtitle":[],"editor":[{"given":"Yoshihiro","family":"Fukumoto","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,4,28]]},"references-count":33,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2016,4,28]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0154024","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,28]]}}}