{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:52:15Z","timestamp":1790232735239,"version":"4.1.0"},"reference-count":50,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2016,5,25]],"date-time":"2016-05-25T00:00:00Z","timestamp":1464134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Shenzhen science and technology innovation project","award":["JCYJ20140416095154398"],"award-info":[{"award-number":["JCYJ20140416095154398"]}]},{"name":"Shenzhen science and technology innovation project","award":["JCYJ20140410164811662"],"award-info":[{"award-number":["JCYJ20140410164811662"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0156017","type":"journal-article","created":{"date-parts":[[2016,5,25]],"date-time":"2016-05-25T17:41:50Z","timestamp":1464198110000},"page":"e0156017","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":22,"title":["Preliminary Proteomic Analysis of A549 Cells Infected with Avian Influenza Virus H7N9 and Influenza A Virus H1N1"],"prefix":"10.1371","volume":"11","author":[{"given":"Xiaoman","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahai","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoxi","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyuan","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihua","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijie","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanwu","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinquan","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhua","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shisong","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,5,25]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"109","DOI":"10.7150\/ijbs.8198","article-title":"Preliminary success in the characterization and management of a sudden breakout of a novel H7N9 influenza A virus","volume":"10","author":"Y Wu","year":"2014","journal-title":"Int J Biol Sci"},{"issue":"9881","key":"ref2","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1016\/S0140-6736(13)60959-9","article-title":"Genesis of avian-origin H7N9 influenza A viruses","volume":"381","author":"M Van Ranst","year":"2013","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1038\/ncomms3854","article-title":"Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility","volume":"4","author":"R Hai","year":"2013","journal-title":"Nat Comms"},{"issue":"9887","key":"ref4","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0140-6736(13)61207-6","article-title":"Human infection with avian influenza A H7N9 virus: an assessment of clinical severity","volume":"382","author":"H Yu","year":"2013","journal-title":"Lancet"},{"issue":"9","key":"ref5","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S1473-3099(13)70167-1","article-title":"The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities","volume":"13","author":"KK To","year":"2013","journal-title":"Lancet Infect Dis"},{"issue":"8","key":"ref6","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1128\/JVI.03095-14","article-title":"A(H7N9) virus results in early induction of proinflammatory cytokine responses in both human lung epithelial and endothelial cells and shows increased human adaptation compared with avian H5N1 virus","volume":"89","author":"H Zeng","year":"2015","journal-title":"J Virol"},{"issue":"6","key":"ref7","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1056\/NEJMoa1304617","article-title":"Epidemiology of human infections with avian influenza A(H7N9) virus in China","volume":"370","author":"Q Li","year":"2014","journal-title":"N Engl J Med"},{"issue":"10","key":"ref8","doi-asserted-by":"crossref","first-page":"5608","DOI":"10.1128\/JVI.03677-13","article-title":"The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses","volume":"88","author":"K Sakai","year":"2014","journal-title":"J Virol"},{"issue":"18","key":"ref9","doi-asserted-by":"crossref","first-page":"10556","DOI":"10.1128\/JVI.00570-14","article-title":"H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in mice","volume":"88","author":"J Morrison","year":"2014","journal-title":"J Virol"},{"issue":"6 Pt B","key":"ref10","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.ygeno.2014.10.012","article-title":"Adaptive evolution of a novel avian-origin influenza A\/H7N9 virus","volume":"104","author":"R Arunachalam","year":"2014","journal-title":"Genomics"},{"issue":"7459","key":"ref11","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/nature12379","article-title":"Biological features of novel avian influenza A (H7N9) virus","volume":"499","author":"J Zhou","year":"2013","journal-title":"Nature"},{"issue":"23","key":"ref12","doi-asserted-by":"crossref","first-page":"9691","DOI":"10.1007\/s00253-014-5852-y","article-title":"Primary study on the lesions and specific proteins in BEAS-2B cells induced with the 2009 A (H1N1) influenza virus","volume":"98","author":"S Fang","year":"2014","journal-title":"Appl Microbiol Biot"},{"issue":"12","key":"ref13","doi-asserted-by":"crossref","first-page":"3316","DOI":"10.1002\/pmic.200800893","article-title":"Quantitative analysis of cellular proteome alterations in human influenza A virus-infected mammalian cell lines","volume":"9","author":"D Vester","year":"2009","journal-title":"Proteomics"},{"issue":"5","key":"ref14","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1093\/infdis\/jis423","article-title":"H5N1 virus causes significant perturbations in host proteome very early in influenza virus-infected primary human monocyte-derived macrophages","volume":"206","author":"CY Cheung","year":"2012","journal-title":"J Infect Dis"},{"issue":"11","key":"ref15","doi-asserted-by":"crossref","first-page":"4511","DOI":"10.1021\/acs.jproteome.5b00196","article-title":"Highly pathogenic H5N1 and novel H7N9 influenza A viruses induce more profound proteomic host responses than seasonal and pandemic H1N1 strains","volume":"14","author":"PF Simon","year":"2015","journal-title":"J Proteome Res"},{"issue":"2","key":"ref16","doi-asserted-by":"crossref","first-page":"e113963","DOI":"10.1371\/journal.pone.0113963","article-title":"Immunogenicity and protective efficacy of a vero cell culture-derived whole-virus H7N9 vaccine in mice and guinea pigs","volume":"10","author":"W Wodal","year":"2015","journal-title":"PLoS One"},{"issue":"7468","key":"ref17","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/nature12392","article-title":"Characterization of H7N9 influenza A viruses isolated from humans","volume":"501","author":"T Watanabe","year":"2013","journal-title":"Nature"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"8039","DOI":"10.1038\/srep08039","article-title":"Amino acids substitutions in the PB2 protein of H7N9 influenza A viruses are important for virulence in mammalian hosts","volume":"5","author":"S Yamayoshi","year":"2015","journal-title":"Sci Rep"},{"issue":"6522","key":"ref19","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/374549a0","article-title":"Anti-inflammatory properties of a platelet-activating factor acetylhydrolase","volume":"374","author":"LW Tjoelker","year":"1995","journal-title":"Nature"},{"issue":"1","key":"ref20","first-page":"69","article-title":"Preparation of proper immunogen by cloning and stable expression of cDNA coding for human hematopoietic stem cell marker CD34 in NIH-3T3 mouse fibroblast cell line","volume":"5","author":"F Shafaghat","year":"2015","journal-title":"Adv Pharm Bull"},{"issue":"6","key":"ref21","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1083\/jcb.133.6.1293","article-title":"Actin organization, bristle morphology, and viability are affected by actin capping protein mutations in Drosophila","volume":"133","author":"R Hopmann","year":"1996","journal-title":"J Cell Biol"},{"issue":"18","key":"ref22","doi-asserted-by":"crossref","first-page":"4389","DOI":"10.1002\/pmic.200900165","article-title":"Differential expression of cell surface proteins in human bone marrow mesenchymal stem cells cultured with or without basic fibroblast growth factor containing medium","volume":"9","author":"SK Lee","year":"2009","journal-title":"Proteomics"},{"issue":"6","key":"ref23","doi-asserted-by":"crossref","first-page":"R175","DOI":"10.1186\/ar2085","article-title":"Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach","volume":"8","author":"K Matsuo","year":"2006","journal-title":"Arthritis Res Ther"},{"issue":"4","key":"ref24","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/0092-8674(95)90080-2","article-title":"Capping protein levels influence actin assembly and cell motility in dictyostelium","volume":"81","author":"C Hug","year":"1995","journal-title":"Cell"},{"issue":"4","key":"ref25","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1534\/genetics.105.049213","article-title":"Mutations in the Drosophila orthologs of the F-actin capping protein alpha-and beta-subunits cause actin accumulation and subsequent retinal degeneration","volume":"171","author":"I Delalle","year":"2005","journal-title":"Genetics"},{"issue":"1","key":"ref26","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/humu.22233","article-title":"Functional analysis of missense mutations of OAT, causing gyrate atrophy of choroid and retina","volume":"34","author":"M Doimo","year":"2013","journal-title":"Hum Mutat"},{"issue":"2","key":"ref27","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ab.2013.05.025","article-title":"Two continuous coupled assays for ornithine-\u03b4-aminotransferase","volume":"440","author":"JI Juncosa","year":"2013","journal-title":"Anal Biochem"},{"issue":"9","key":"ref28","doi-asserted-by":"crossref","first-page":"e136914","DOI":"10.1371\/journal.pone.0136914","article-title":"Mycobacterium tuberculosis is a natural ornithine aminotransferase (rocD) mutant and depends on Rv2323c for growth on arginine","volume":"10","author":"A Hampel","year":"2015","journal-title":"PLoS One"},{"issue":"1","key":"ref29","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jplph.2011.08.001","article-title":"Exogenous ornithine is an effective precursor and the \u03b4-ornithine amino transferase pathway contributes to proline accumulation under high N recycling in salt-stressed cashew leaves","volume":"169","author":"IMA Da Rocha","year":"2012","journal-title":"J Plant Physiol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1471-2229-8-40","article-title":"Ornithine-\u03b4-aminotransferase is essential for arginine catabolism but not for proline biosynthesis","volume":"8","author":"D Funck","year":"2008","journal-title":"BMC Plant Biol"},{"issue":"Pt 8","key":"ref31","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.mycres.2007.05.012","article-title":"The role of ornithine aminotransferase in fruiting body formation of the mushroom Agaricus bisporus","volume":"111","author":"MJ Wagemaker","year":"2007","journal-title":"Mycol Res"},{"issue":"7","key":"ref32","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1073\/pnas.0610832104","article-title":"Diazonamide toxins reveal an unexpected function for ornithine delta-amino transferase in mitotic cell division","volume":"104","author":"G Wang","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"9","key":"ref33","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/gcc.22268","article-title":"The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma","volume":"54","author":"R Wagener","year":"2015","journal-title":"Genes Chromosomes Cancer"},{"issue":"3","key":"ref34","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1007\/s12264-012-1242-6","article-title":"Possible novel roles of poly(rC)-binding protein 1 in SH-SY5Y neurocytes: an analysis using a dynamic Bayesian network","volume":"28","author":"LR Huo","year":"2012","journal-title":"Neurosci Bull"},{"issue":"10","key":"ref35","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1016\/j.bbapap.2010.07.002","article-title":"Identification of differentially expressed transcripts and translatants targeted by knock-down of endogenous PCBP1","volume":"1804","author":"LR Huo","year":"2010","journal-title":"Biochim Biophys Acta"},{"issue":"7","key":"ref36","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1097\/IGC.0b013e3182606ac3","article-title":"Down-regulation of Poly(rC)-binding protein 1 correlates with the malignant transformation of hydatidiform moles","volume":"22","author":"Z Shi","year":"2012","journal-title":"Int J Gynecol Cancer"},{"issue":"11","key":"ref37","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1016\/j.bbapap.2008.06.017","article-title":"Identification of transcripts and translatants targeted by overexpressed PCBP1","volume":"1784","author":"LR Huo","year":"2008","journal-title":"Biochim Biophys Acta"},{"issue":"4","key":"ref38","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.bbrc.2009.04.049","article-title":"The effect of hypusine modification on the intracellular localization of eIF5A","volume":"383","author":"SB Lee","year":"2009","journal-title":"Biochem Biophys Res Commun"},{"issue":"3","key":"ref39","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1159\/000358658","article-title":"Comparative proteomic analysis of anti-cancer mechanism by periplocin treatment in lung cancer cells","volume":"33","author":"Z Lu","year":"2014","journal-title":"Cell Physiol Biochem"},{"issue":"5257","key":"ref40","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1126\/science.271.5257.1858","article-title":"Inhibition of HIV-1 replication in lymphocytes by mutants of the Rev cofactor eIF-5A","volume":"271","author":"D Bevec","year":"1996","journal-title":"Science"},{"issue":"1","key":"ref41","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.ygyno.2004.03.018","article-title":"Eukaryotic initiation factor 5A-1 (eIF5A-1) as a diagnostic marker for aberrant proliferation in intraepithelial neoplasia of the vulva","volume":"94","author":"BM Cracchiolo","year":"2004","journal-title":"Gynecol Oncol"},{"issue":"6","key":"ref42","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1172\/JCI38924","article-title":"The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice","volume":"120","author":"B Maier","year":"2010","journal-title":"J Clin Invest"},{"issue":"2","key":"ref43","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00726-007-0533-0","article-title":"Is there a role for eIF5A in translation?","volume":"33","author":"CF Zanelli","year":"2007","journal-title":"Amino Acids"},{"issue":"3","key":"ref44","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s10059-011-0026-6","article-title":"Identification of the target proteins of rosiglitazone in 3T3-L1 adipocytes through proteomic analysis of cytosolic and secreted proteins","volume":"31","author":"H Hwang","year":"2011","journal-title":"Mol Cells"},{"issue":"1\u20132","key":"ref45","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/S1388-1981(00)00114-1","article-title":"Platelet-activating factor acetylhydrolases in health and disease","volume":"1488","author":"LW Tjoelker","year":"2000","journal-title":"Biochim Biophys Acta"},{"issue":"29","key":"ref46","doi-asserted-by":"crossref","first-page":"18567","DOI":"10.1074\/jbc.273.29.18567","article-title":"Switching of platelet-activating factor acetylhydrolase catalytic subunits in developing rat brain","volume":"273","author":"H Manya","year":"1998","journal-title":"J Biol Chem"},{"issue":"16","key":"ref47","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1016\/j.febslet.2007.05.065","article-title":"Isolation and characterization of nudC from mouse macrophages, a gene implicated in the inflammatory response through the regulation of PAF-AH(I) activity","volume":"581","author":"J Riera","year":"2007","journal-title":"FEBS Lett"},{"issue":"45","key":"ref48","doi-asserted-by":"crossref","first-page":"31827","DOI":"10.1074\/jbc.274.45.31827","article-title":"Biochemical characterization of various catalytic complexes of the brain platelet-activating factor acetylhydrolase","volume":"274","author":"H Manya","year":"1999","journal-title":"J Biol Chem"},{"key":"ref49","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2010.00019","article-title":"PAF-AH catalytic subunits modulate the Wnt pathway in developing GABAergic neurons","volume":"4","author":"I Livnat","year":"2010","journal-title":"Front Cell Neurosci"},{"issue":"3","key":"ref50","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0005-2760(94)00192-2","article-title":"Platelet-activating factor and its analogs: metabolic pathways and related intracellular processes","volume":"1254","author":"F Snyder","year":"1995","journal-title":"Biochim Biophys Acta"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0156017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T21:29:17Z","timestamp":1567978157000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0156017"}},"subtitle":[],"editor":[{"given":"Suryaprakash","family":"Sambhara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,5,25]]},"references-count":50,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2016,5,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0156017","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,25]]}}}