{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:34:03Z","timestamp":1791304443821,"version":"4.3.1"},"reference-count":78,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T00:00:00Z","timestamp":1464048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0156084","type":"journal-article","created":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T17:30:03Z","timestamp":1464111003000},"page":"e0156084","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":35,"title":["Cytokine and Chemokine Expression in Kidneys during Chronic Leptospirosis in Reservoir and Susceptible Animal Models"],"prefix":"10.1371","volume":"11","author":[{"given":"Mariko","family":"Matsui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Roche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Geroult","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Estelle","family":"Soup\u00e9-Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Monchy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Huerre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyrille","family":"Goarant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,5,24]]},"reference":[{"issue":"9","key":"ref1","doi-asserted-by":"crossref","first-page":"e0003898","DOI":"10.1371\/journal.pntd.0003898","article-title":"Global Morbidity and Mortality of Leptospirosis: A Systematic Review","volume":"9","author":"F Costa","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"issue":"10","key":"ref2","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1038\/nrmicro2208","article-title":"Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen","volume":"7","author":"AI Ko","year":"2009","journal-title":"Nature reviews Microbiology"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/nrneph.2010.1","article-title":"ARF, AKI, or ATN?","volume":"6","author":"RW Schrier","year":"2010","journal-title":"Nature reviews Nephrology"},{"issue":"2","key":"ref4","doi-asserted-by":"crossref","first-page":"441.e5","DOI":"10.1016\/j.ajem.2012.04.007","article-title":"Acute kidney injury and thrombocytopenic fever\u2014consider the infrequent causes","volume":"31","author":"CS Haas","year":"2013","journal-title":"Am J Emerg Med"},{"key":"ref5","volume":"2011","year":"2011"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S1413-8670(10)70002-7","article-title":"Clinical presentation of leptospirosis: a retrospective study of 201 patients in a metropolitan city of Brazil","volume":"14","author":"EF Daher","year":"2010","journal-title":"Braz J Infect Dis"},{"issue":"6","key":"ref7","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1038\/ki.1980.95","article-title":"Pathogenesis of renal disease in leptospirosis: Clinical and experimental studies","volume":"17","author":"V Sitprija","year":"1980","journal-title":"Kidney Int"},{"issue":"1","key":"ref8","first-page":"7","article-title":"The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran; A follow-up study","volume":"7","author":"R Ghasemian","year":"2016","journal-title":"Caspian journal of internal medicine"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1186\/1756-0500-7-398","article-title":"Long term outcome of acute kidney injury due to leptospirosis? A longitudinal study in Sri Lanka","volume":"7","author":"NJ Herath","year":"2014","journal-title":"BMC research notes"},{"issue":"10","key":"ref10","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1093\/ndt\/gfi014","article-title":"A case of leptospirosis presenting with end-stage renal failure","volume":"20","author":"EM Atasoyu","year":"2005","journal-title":"Nephrol Dial Transplant"},{"issue":"5\u20136","key":"ref11","doi-asserted-by":"crossref","first-page":"249","DOI":"10.4269\/ajtmh.2000.63.249","article-title":"Asymptomatic infection and risk factors for leptospirosis in Nicaragua","volume":"63","author":"DA Ashford","year":"2000","journal-title":"The American journal of tropical medicine and hygiene"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1093\/ije\/28.3.583","article-title":"Factors associated with clinical leptospirosis: a population-based case-control study in the Seychelles (Indian Ocean)","volume":"28","author":"P Bovet","year":"1999","journal-title":"Int J Epidemiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"169013","DOI":"10.1155\/2012\/169013","article-title":"Prolonged leptospira urinary shedding in a 10-year-old girl","volume":"2012","author":"E Chow","year":"2012","journal-title":"Case reports in pediatrics"},{"issue":"8","key":"ref14","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1128\/JCM.32.8.1894-1898.1994","article-title":"Detection of leptospires in urine by PCR for early diagnosis of leptospirosis","volume":"32","author":"AE Bal","year":"1994","journal-title":"J Clin Microbiol"},{"issue":"2","key":"ref15","doi-asserted-by":"crossref","first-page":"e612","DOI":"10.1371\/journal.pntd.0000612","article-title":"Asymptomatic Renal Colonization of Humans in the Peruvian Amazon by <italic>Leptospira<\/italic>","volume":"4","author":"CA Ganoza","year":"2010","journal-title":"PLoS neglected tropical diseases"},{"issue":"10","key":"ref16","doi-asserted-by":"crossref","first-page":"e0004105","DOI":"10.1371\/journal.pntd.0004105","article-title":"Overlooked Risk for Chronic Kidney Disease after Leptospiral Infection: A Population-Based Survey and Epidemiological Cohort Evidence","volume":"9","author":"HY Yang","year":"2015","journal-title":"PLoS neglected tropical diseases"},{"issue":"3","key":"ref17","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1053\/j.ajkd.2013.10.062","article-title":"CKD of unknown origin in Central America: the case for a Mesoamerican nephropathy","volume":"63","author":"R Correa-Rotter","year":"2014","journal-title":"American journal of kidney diseases: the official journal of the National Kidney Foundation"},{"issue":"10","key":"ref18","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.micinf.2015.08.005","article-title":"Mesoamerican nephropathy: a neglected tropical disease with an infectious etiology?","volume":"17","author":"KO Murray","year":"2015","journal-title":"Microbes and infection \/ Institut Pasteur"},{"key":"ref19","article-title":"CKD and Infectious Diseases in Asia Pacific: Challenges and Opportunities","author":"V Jha","year":"2016","journal-title":"American journal of kidney diseases: the official journal of the National Kidney Foundation"},{"issue":"1","key":"ref20","doi-asserted-by":"crossref","first-page":"55","DOI":"10.7589\/0090-3558-12.1.55","article-title":"Some observations on chronic leptospiral carrier state in gerbils experimentally infected with Leptospira grippotyphosa","volume":"12","author":"DN Tripathy","year":"1976","journal-title":"Journal of wildlife diseases"},{"issue":"1","key":"ref21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02122002","article-title":"Observations of the carrier state in hamsters infected with Leptospira interrogans serotype Pomona","volume":"158","author":"NG Miller","year":"1972","journal-title":"Med Microbiol Immunol"},{"issue":"2","key":"ref22","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1177\/0300985811409252","article-title":"Development of Chronic and Acute Golden Syrian Hamster Infection Models With Leptospira borgpetersenii Serovar Hardjo","volume":"49","author":"RL Zuerner","year":"2012","journal-title":"Veterinary pathology"},{"issue":"5","key":"ref23","doi-asserted-by":"crossref","first-page":"982","DOI":"10.4269\/ajtmh.14-0462","article-title":"Experimental Hamster Infection with a Strain of Leptospira borgpetersenii Ballum Isolated from a Reservoir Mouse in New Caledonia","volume":"92","author":"M Matsui","year":"2015","journal-title":"The American journal of tropical medicine and hygiene"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S1473-3099(03)00830-2","article-title":"Leptospirosis: a zoonotic disease of global importance","volume":"3","author":"AR Bharti","year":"2003","journal-title":"Lancet Infect Dis"},{"issue":"5","key":"ref25","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1354\/vp.08-VP-0265-N-REV","article-title":"Host-pathogen interactions in the kidney during chronic leptospirosis","volume":"46","author":"A Monahan","year":"2009","journal-title":"Veterinary pathology"},{"issue":"11","key":"ref26","doi-asserted-by":"crossref","first-page":"4952","DOI":"10.1128\/IAI.00511-08","article-title":"A proteomic analysis of Leptospira being shed in urine of chronically infected hosts","volume":"76","author":"AM Monahan","year":"2008","journal-title":"Infect Immun"},{"issue":"5","key":"ref27","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1089\/vbz.2008.0081","article-title":"Leptospirosis in Wild and Domestic Carnivores in Natural Areas in Andalusia, Spain","volume":"9","author":"J Millan","year":"2008","journal-title":"Vector borne and zoonotic diseases"},{"issue":"4","key":"ref28","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.jcpa.2007.08.001","article-title":"Morphological alterations in the kidney of rats with natural and experimental Leptospira infection","volume":"137","author":"M Tucunduva de Faria","year":"2007","journal-title":"Journal of comparative pathology"},{"issue":"11","key":"ref29","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1681\/ASN.V11112017","article-title":"<italic>Leptospira<\/italic> outer membrane protein activates NF-kB and downstream genes expressed in medullary thick ascending limb cells","volume":"11","author":"CW Yang","year":"2000","journal-title":"J Am Soc Nephrol"},{"issue":"8","key":"ref30","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1097\/01.ASN.0000022007.91733.62","article-title":"The Leptospira outer membrane protein LipL32 induces tubulointerstitial nephritis-mediated gene expression in mouse proximal tubule cells","volume":"13","author":"CW Yang","year":"2002","journal-title":"J Am Soc Nephrol"},{"issue":"8","key":"ref31","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.1073\/pnas.90.8.3491","article-title":"Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes","volume":"90","author":"DA Geller","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"ref32","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1046\/j.1523-1755.2001.0590031059.x","article-title":"Nitric oxide in unilateral ureteral obstruction: effect on regional renal blood flow","volume":"59","author":"NJ Hegarty","year":"2001","journal-title":"Kidney international"},{"issue":"5","key":"ref33","doi-asserted-by":"crossref","first-page":"392","DOI":"10.4103\/0971-4065.103927","article-title":"Reversible acute kidney injury due to bilateral papillary necrosis in a patient with leptospirosis and diabetes mellitus","volume":"22","author":"PS Subrahmanian","year":"2012","journal-title":"Indian journal of nephrology"},{"issue":"3","key":"ref34","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.micpath.2011.03.011","article-title":"Role of inducible nitric oxide synthase in the pathogenesis of experimental leptospirosis","volume":"51","author":"G Pretre","year":"2011","journal-title":"Microb Pathog"},{"issue":"1","key":"ref35","doi-asserted-by":"crossref","first-page":"e2664","DOI":"10.1371\/journal.pntd.0002664","article-title":"Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways","volume":"8","author":"M Fanton d'Andon","year":"2014","journal-title":"PLoS neglected tropical diseases"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"70","DOI":"10.2174\/1874312901206010070","article-title":"Mediators of fibrosis","volume":"6","author":"M Trojanowska","year":"2012","journal-title":"The open rheumatology journal"},{"issue":"10","key":"ref37","doi-asserted-by":"crossref","first-page":"e1361","DOI":"10.1371\/journal.pntd.0001361","article-title":"Rodent abundance dynamics and leptospirosis carriage in an area of hyper-endemicity in New Caledonia","volume":"5","author":"J Perez","year":"2011","journal-title":"PLoS neglected tropical diseases"},{"key":"ref38","unstructured":"Faine S, Adler B, Bolin C, Perolat P. Leptospira and Leptospirosis, Second Edition. MedSci, editor. Melbourne, Australia: MedSci, Melbourne, Vic. Australia; 1999. 272 p."},{"issue":"1","key":"ref39","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/kisup.2014.3","article-title":"What is the best way to measure renal fibrosis?: A pathologist&apos;s perspective","volume":"4","author":"AB Farris","year":"2014","journal-title":"Kidney international supplements"},{"issue":"2","key":"ref40","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1128\/IAI.01533-13","article-title":"Oral immunization with E. coli expressing a lipidated form of LigA protects hamsters against challenge with Leptospira interrogans serovar Copenhageni","volume":"82","author":"K Lourdault","year":"2014","journal-title":"Infect Immun"},{"issue":"1","key":"ref41","first-page":"5","article-title":"Method of Warthin-Starry modified with pyrocatechol: interest for revealing spirochetes and infectious agents [M\u00e9thode de Warthin-Starry modifi\u00e9e au pyrocatechol: int\u00e9r\u00eat pour la mise en \u00e9vidence des spiroch\u00e8tes et agents infectieux]","volume":"6","author":"N Wuscher","year":"1993","journal-title":"Revue fran\u00e7aise d'histotechnologie"},{"issue":"11","key":"ref42","doi-asserted-by":"crossref","first-page":"4480","DOI":"10.1128\/IAI.05727-11","article-title":"Gene expression profiles of immune mediators and histopathological findings in animal models of leptospirosis: comparison between susceptible hamsters and resistant mice","volume":"79","author":"M Matsui","year":"2011","journal-title":"Infect Immun"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.femsle.2005.06.011","article-title":"A rapid and quantitative method for the detection of <italic>Leptospira<\/italic> species in human leptospirosis","volume":"249","author":"F Merien","year":"2005","journal-title":"FEMS Microbiol Lett"},{"issue":"3","key":"ref44","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.diagmicrobio.2009.03.014","article-title":"Detection of pathogenic Leptospira spp. through TaqMan polymerase chain reaction targeting the LipL32 gene","volume":"64","author":"RA Stoddard","year":"2009","journal-title":"Diagnostic microbiology and infectious disease"},{"issue":"12","key":"ref45","doi-asserted-by":"crossref","first-page":"4693","DOI":"10.1128\/IAI.01115-15","article-title":"Mouse Model for Sublethal Leptospira interrogans Infection","volume":"83","author":"L Richer","year":"2015","journal-title":"Infection and immunity"},{"issue":"Pt 2","key":"ref46","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1099\/mic.0.072439-0","article-title":"High virulence in hamsters of four dominant Leptospira serovars isolated from rats in the Philippines","volume":"160","author":"SY Villanueva","year":"2014","journal-title":"Microbiology (Reading, England)"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1099\/jmm.0.021089-0","article-title":"Different outcomes of experimental leptospiral infection in mouse strains with distinct genotypes","volume":"59","author":"CS Santos","year":"2010","journal-title":"J Med Microbiol"},{"issue":"7","key":"ref48","doi-asserted-by":"crossref","first-page":"e102860","DOI":"10.1371\/journal.pone.0102860","article-title":"Decay-accelerating factor 1 deficiency exacerbates leptospiral-induced murine chronic nephritis and renal fibrosis","volume":"9","author":"MF Ferrer","year":"2014","journal-title":"PloS one"},{"issue":"1","key":"ref49","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.4102\/jsava.v83i1.69","article-title":"Evaluation of &apos;white-spotted kidneys&apos; associated with leptospirosis by polymerase chain reaction based LipL32 gene in slaughtered cows","volume":"83","author":"S Azizi","year":"2012","journal-title":"Journal of the South African Veterinary Association"},{"issue":"7","key":"ref50","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1046\/j.1439-0442.2001.00355.x","article-title":"Immunoperoxidase and histopathological examinations of leptospiral nephritis in cattle","volume":"48","author":"Z Yener","year":"2001","journal-title":"Journal of veterinary medicine A, Physiology, pathology, clinical medicine"},{"key":"ref51","unstructured":"Pierce PF, Utz JP, Lack EE. Pathology of infectious diseases. Volume 1. In: Connor DH, Chandler FW, Manz HJ, Schwartz DA, Lack EE, editors.: Appleton &amp; Lange; 1997."},{"key":"ref52","first-page":"303","article-title":"Tropical Infectious Diseases: Principles, Pathogens and Practice (Third Edition). Tropical Infectious Diseases: Principles, Pathogens and Practice","author":"W-J Shieh","year":"2011"},{"issue":"Suppl 2","key":"ref53","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1097\/01.PAT.0000454142.79156.d7","article-title":"Infectious Diseases and Tropical Disease Pathology: SY16-2A PATHOLOGY OF LEPTOSPIROSIS: AUTOPSY STUDY","volume":"46","author":"V Boonpucknavig","year":"2014","journal-title":"Pathology"},{"issue":"11","key":"ref54","doi-asserted-by":"crossref","first-page":"4480","DOI":"10.1128\/IAI.05727-11","article-title":"Gene expression profiles of immune mediators and histopathological findings in animal models of leptospirosis: comparison between susceptible hamsters and resistant mice","volume":"79","author":"M Matsui","year":"2011","journal-title":"Infection and immunity"},{"issue":"4","key":"ref55","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1590\/S1517-838246420140873","article-title":"Heterogenic colonization patterns by Leptospira interrogans in Rattus norvegicus from urban slums","volume":"46","author":"AA Santos","year":"2015","journal-title":"Brazilian journal of microbiology: [publication of the Brazilian Society for Microbiology]"},{"issue":"Pt 5","key":"ref56","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1099\/mic.0.2007\/014746-0","article-title":"Biofilm formation by saprophytic and pathogenic leptospires","volume":"154","author":"P Ristow","year":"2008","journal-title":"Microbiology"},{"issue":"1","key":"ref57","first-page":"35","article-title":"Cell aggregation: a mechanism of pathogenic <italic>Leptospira<\/italic> to survive in fresh water","volume":"7","author":"G Trueba","year":"2004","journal-title":"Int Microbiol"},{"issue":"7","key":"ref58","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1093\/infdis\/jit659","article-title":"Identification of collagenase as a critical virulence factor for invasiveness and transmission of pathogenic Leptospira species","volume":"209","author":"K Kassegne","year":"2014","journal-title":"The Journal of infectious diseases"},{"issue":"26","key":"ref59","doi-asserted-by":"crossref","first-page":"14620","DOI":"10.1073\/pnas.94.26.14620","article-title":"Identification of functional domains on human interleukin 10","volume":"94","author":"B Gesser","year":"1997","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1146\/annurev.immunol.19.1.683","article-title":"Interleukin-10 and the interleukin-10 receptor","volume":"19","author":"KW Moore","year":"2001","journal-title":"Annual review of immunology"},{"issue":"2","key":"ref61","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.ajpath.2013.05.001","article-title":"Regulation of pathogenic Th17 cell differentiation by IL-10 in the development of glomerulonephritis","volume":"183","author":"R Zhang","year":"2013","journal-title":"The American journal of pathology"},{"key":"ref62","article-title":"Induction of TNF-alfa and CXCL-2 mRNAs in different organs of mice infected with pathogenic Leptospira","author":"JB da Silva","year":"2012","journal-title":"Microb Pathog"},{"issue":"1","key":"ref63","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.actatropica.2007.09.004","article-title":"Experimental infection in tumor necrosis factor alpha receptor, interferon gamma and interleukin 4 deficient mice by pathogenic Leptospira interrogans","volume":"105","author":"DA Athanazio","year":"2008","journal-title":"Acta tropica"},{"issue":"7","key":"ref64","doi-asserted-by":"crossref","first-page":"e0132694","DOI":"10.1371\/journal.pone.0132694","article-title":"Comparison of Bacterial Burden and Cytokine Gene Expression in Golden Hamsters in Early Phase of Infection with Two Different Strains of Leptospira interrogans","volume":"10","author":"R Fujita","year":"2015","journal-title":"PloS one"},{"issue":"6","key":"ref65","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/S1359-6101(02)00045-X","article-title":"Macrophage inflammatory protein-1","volume":"13","author":"P Menten","year":"2002","journal-title":"Cytokine & growth factor reviews"},{"issue":"4","key":"ref66","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S1567-5769(01)00004-2","article-title":"Chemokines in renal diseases","volume":"1","author":"T Wada","year":"2001","journal-title":"International immunopharmacology"},{"issue":"6","key":"ref67","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1111\/j.1523-1755.2004.66038.x","article-title":"CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome","volume":"66","author":"V Vielhauer","year":"2004","journal-title":"Kidney Int"},{"issue":"3","key":"ref68","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S1359-6101(97)00015-4","article-title":"The immunobiology of interferon-gamma inducible protein 10 kD (IP-10): a novel, pleiotropic member of the C-X-C chemokine superfamily","volume":"8","author":"LF Neville","year":"1997","journal-title":"Cytokine & growth factor reviews"},{"issue":"1","key":"ref69","first-page":"301","article-title":"Interferon-inducible protein-10 is highly expressed in rats with experimental nephrosis","volume":"148","author":"M Gomez-Chiarri","year":"1996","journal-title":"The American journal of pathology"},{"issue":"3","key":"ref70","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1046\/j.1365-2249.1996.d01-864.x","article-title":"Expression of leucocyte chemoattractants by interstitial renal fibroblasts: up-regulation by drugs associated with interstitial fibrosis","volume":"106","author":"S Gonzalez-Cuadrado","year":"1996","journal-title":"Clinical and experimental immunology"},{"issue":"2","key":"ref71","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0002-9440(10)63152-5","article-title":"CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis","volume":"164","author":"S Segerer","year":"2004","journal-title":"The American journal of pathology"},{"issue":"5","key":"ref72","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.cimid.2009.05.001","article-title":"Expression of TNF-alpha, TGF-beta, IP-10 and IL-10 mRNA in kidneys of hamsters infected with pathogenic Leptospira","volume":"33","author":"A Lowanitchapat","year":"2010","journal-title":"Comparative immunology, microbiology and infectious diseases"},{"key":"ref73","article-title":"CXCL10 Induces the Recruitment of Monocyte Derived Macrophages into Kidney, which Aggravate Puromycin Aminonucleoside Nephrosis","author":"D Petrovic-Djergovic","year":"2015","journal-title":"Clinical and experimental immunology"},{"issue":"1","key":"ref74","doi-asserted-by":"crossref","first-page":"e12","DOI":"10.1159\/000106505","article-title":"Blockade of IP-10\/CXCR3 promotes progressive renal fibrosis","volume":"107","author":"I Nakaya","year":"2007","journal-title":"Nephron Experimental nephrology"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3389\/fimmu.2015.00059","article-title":"Macrophages at the fork in the road to health or disease","volume":"6","author":"CD Mills","year":"2015","journal-title":"Frontiers in immunology"},{"issue":"1","key":"ref76","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10157-008-0119-5","article-title":"Chemokine\/chemokine receptor-mediated inflammation regulates pathologic changes from acute kidney injury to chronic kidney disease","volume":"13","author":"K Furuichi","year":"2009","journal-title":"Clinical and experimental nephrology"},{"issue":"9","key":"ref77","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1038\/ki.2011.217","article-title":"Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis","volume":"80","author":"HJ Anders","year":"2011","journal-title":"Kidney Int"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s40169-015-0047-4","article-title":"The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases","volume":"4","author":"PJ Wermuth","year":"2015","journal-title":"Clinical and translational medicine"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0156084","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T16:00:04Z","timestamp":1692374404000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0156084"}},"subtitle":[],"editor":[{"given":"R. Mark","family":"Wooten","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,5,24]]},"references-count":78,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2016,5,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0156084","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,24]]}}}