{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:15:59Z","timestamp":1793330159101,"version":"4.5.0"},"reference-count":95,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2016,6,28]],"date-time":"2016-06-28T00:00:00Z","timestamp":1467072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH-funded MIND Institute Intellectual and Developmental Disabilities Research Center","award":["U54 HD079125"],"award-info":[{"award-number":["U54 HD079125"]}]},{"name":"UC Davis Behavioral Health Center of Excellence","award":["Pilot Award"],"award-info":[{"award-number":["Pilot Award"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0158150","type":"journal-article","created":{"date-parts":[[2016,6,28]],"date-time":"2016-06-28T17:30:15Z","timestamp":1467135015000},"page":"e0158150","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":69,"title":["Behavioral Phenotyping of Juvenile Long-Evans and Sprague-Dawley Rats: Implications for Preclinical Models of Autism Spectrum Disorders"],"prefix":"10.1371","volume":"11","author":[{"given":"Katherine M.","family":"Ku","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth K.","family":"Weir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill L.","family":"Silverman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert F.","family":"Berman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa D.","family":"Bauman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,6,28]]},"reference":[{"key":"ref1","article-title":"Diagnostic and statistical manual of mental disorders: DSM-5","year":"2013"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2217\/npy.13.18","article-title":"Is &apos;bench-to-bedside&apos; realistic for autism? An integrative neuroscience approach","volume":"3","author":"MD Bauman","year":"2013","journal-title":"Neuropsychiatry (London)"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1038\/npp.2013.342","article-title":"Innovative drugs to treat depression: did animal models fail to be predictive or did clinical trials fail to detect effects?","volume":"39","author":"C Belzung","year":"2014","journal-title":"Neuropsychopharmacology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.bcp.2013.08.006","article-title":"Animal models of human disease: challenges in enabling translation","volume":"87","author":"P McGonigle","year":"2014","journal-title":"Biochem Pharmacol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-61779-458-2_1","article-title":"New Frontiers in Animal Research of Psychiatric Illness","volume":"829","author":"A Kaffman","year":"2012","journal-title":"Methods Mol Biol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1001\/jamapsychiatry.2013.2184","article-title":"The neuropsychiatric translational revolution: still very early and still very challenging","volume":"70","author":"L Braff","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1038\/nrn2851","article-title":"Behavioural phenotyping assays for mouse models of autism","volume":"11","author":"JL Silverman","year":"2010","journal-title":"Nat Rev Neurosci"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/aur.216","article-title":"The autism diagnosis in translation: shared affect in children and mouse models of ASD","volume":"4","author":"SL Bishop","year":"2011","journal-title":"Autism Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.bbr.2013.05.047","article-title":"Behavioural methods used in rodent models of autism spectrum disorders: current standards and new developments","volume":"251","author":"M Wohr","year":"2013","journal-title":"Behav Brain Res"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.bbr.2009.09.029","article-title":"Juvenile peer play experience and the development of the orbitofrontal and medial prefrontal cortices","volume":"207","author":"HC Bell","year":"2010","journal-title":"Behav Brain Res"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s00441-013-1607-9","article-title":"Affective communication in rodents: ultrasonic vocalizations as a tool for research on emotion and motivation","volume":"354","author":"M Wohr","year":"2013","journal-title":"Cell Tissue Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1038\/npp.2013.47","article-title":"Early social experience is critical for the development of cognitive control and dopamine modulation of prefrontal cortex function","volume":"38","author":"PJ Baarendse","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0149-7634(96)00020-6","article-title":"The neurobiology of social play behavior in rats","volume":"21","author":"LJ Vanderschuren","year":"1997","journal-title":"Neurosci Biobehav Rev"},{"key":"ref14","article-title":"Rough-and-tumble play as a window on animal communication","author":"E Palagi","year":"2015","journal-title":"Biol Rev Camb Philos Soc"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/sj.npp.1300518","article-title":"Behavioral alterations in rats prenatally exposed to valproic acid: animal model of autism","volume":"30","author":"T Schneider","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"ref16","article-title":"Effects of prenatal exposure to valproic acid on the development of juvenile-typical social play in rats","author":"S Raza","year":"2015","journal-title":"Behav Pharmacol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.neulet.2009.12.054","article-title":"Behavior and serotonergic disorders in rats exposed prenatally to valproate: a model for autism","volume":"470","author":"D Dufour-Rainfray","year":"2010","journal-title":"Neurosci Lett"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1037\/a0035988","article-title":"Fmr1 and Nlgn3 knockout rats: novel tools for investigating autism spectrum disorders","volume":"128","author":"SM Hamilton","year":"2014","journal-title":"Behav Neurosci"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.bbr.2014.04.035","article-title":"Autism-related behavioral phenotypes in an inbred rat substrain","volume":"269","author":"Y Zhang-James","year":"2014","journal-title":"Behav Brain Res"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.bbr.2013.04.022","article-title":"Rats selectively bred for low levels of play-induced 50 kHz vocalizations as a model for autism spectrum disorders: a role for NMDA receptors","volume":"251","author":"J Burgdorf","year":"2013","journal-title":"Behav Brain Res"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.lfs.2015.02.027","article-title":"Prenatal zinc prevents communication impairments and BDNF disturbance in a rat model of autism induced by prenatal lipopolysaccharide exposure","volume":"130","author":"TB Kirsten","year":"2015","journal-title":"Life Sci"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"e0134565","DOI":"10.1371\/journal.pone.0134565","article-title":"Lipopolysaccharide Exposure Induces Maternal Hypozincemia, and Prenatal Zinc Treatment Prevents Autistic-Like Behaviors and Disturbances in the Striatal Dopaminergic and mTOR Systems of Offspring","volume":"10","author":"TB Kirsten","year":"2015","journal-title":"PLoS One"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.lfs.2014.10.019","article-title":"Prenatal zinc reduces stress response in adult rat offspring exposed to lipopolysaccharide during gestation","volume":"120","author":"MC Galvao","year":"2015","journal-title":"Life Sci"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1097\/FBP.0000000000000163","article-title":"Modeling autism-relevant behavioral phenotypes in rats and mice: Do &apos;autistic&apos; rodents exist?","volume":"26","author":"M Servadio","year":"2015","journal-title":"Behav Pharmacol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1007\/s00213-013-3268-5","article-title":"Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: current status and future perspectives","volume":"231","author":"MJ Kas","year":"2014","journal-title":"Psychopharmacology (Berl)"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/ab.2480150405","article-title":"Different levels of complexity in the play fighting by muroid rodents appear to result from different levels of intensity of attack and defense","author":"SM Pellis","year":"1989","journal-title":"Aggress Behav"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/dev.420230303","article-title":"Differential rates of attack, defense, and counterattack during the developmental decrease in play fighting by male and female rats","volume":"23","author":"SM Pellis","year":"1990","journal-title":"Dev Psychobiol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/(SICI)1098-2302(199711)31:3<193::AID-DEV4>3.0.CO;2-N","article-title":"The prejuvenile onset of play fighting in laboratory rats (Rattus norvegicus)","volume":"31","author":"SM Pellis","year":"1997","journal-title":"Dev Psychobiol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0149-7634(97)00071-7","article-title":"Play fighting of rats in comparative perspective: a schema for neurobehavioral analyses","volume":"23","author":"SM Pellis","year":"1998","journal-title":"Neurosci Biobehav Rev"},{"key":"ref30","first-page":"e4288","article-title":"Peering into the dynamics of social interactions: measuring play fighting in rats","author":"BT Himmler","year":"2013","journal-title":"J Vis Exp"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1037\/a0032187","article-title":"How domestication modulates play behavior: a comparative analysis between wild rats and a laboratory strain of Rattus norvegicus","volume":"127","author":"BT Himmler","year":"2013","journal-title":"J Comp Psychol"},{"key":"ref32","doi-asserted-by":"crossref","DOI":"10.46867\/ijcp.2014.27.03.09","article-title":"The Development of Strain Typical Defensive Patterns in the Play Fighting of Laboratory Rats","volume":"27","author":"SM Himmler","year":"2014","journal-title":"International Journal of Comparative Psychology"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1037\/a0036104","article-title":"Domestication and diversification: a comparative analysis of the play fighting of the Brown Norway, Sprague-Dawley, and Wistar laboratory strains of (Rattus norvegicus)","volume":"128","author":"SM Himmler","year":"2014","journal-title":"J Comp Psychol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s002130050327","article-title":"Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies","volume":"132","author":"JN Crawley","year":"1997","journal-title":"Psychopharmacology (Berl)"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3758\/s13420-014-0163-9","article-title":"Comparison of spatial learning in the partially baited radial-arm maze task between commonly used rat strains: Wistar, Spargue-Dawley, Long-Evans, and outcrossed Wistar\/Sprague-Dawley","volume":"43","author":"C Gokcek-Sarac","year":"2015","journal-title":"Learn Behav"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.physbeh.2015.03.001","article-title":"Strain-dependent effects on acquisition and reversal of visual and spatial tasks in a rat touchscreen battery of cognition","volume":"144","author":"G Kumar","year":"2015","journal-title":"Physiol Behav"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1002\/dev.420250804","article-title":"Long-Evans and Sprague-Dawley rats differ in their spatial navigation performance during ontogeny and at maturity","volume":"25","author":"J Tonkiss","year":"1992","journal-title":"Dev Psychobiol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"e93411","DOI":"10.1371\/journal.pone.0093411","article-title":"Comprehensive behavioural analysis of Long Evans and Sprague-Dawley rats reveals differential effects of housing conditions on tests relevant to neuropsychiatric disorders","volume":"9","author":"KM Turner","year":"2014","journal-title":"PLoS One"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0166-4328(03)00143-8","article-title":"Long-Evans and Sprague-Dawley rats have similar skilled reaching success and limb representations in motor cortex but different movements: some cautionary insights into the selection of rat strains for neurobiological motor research","volume":"145","author":"IQ Whishaw","year":"2003","journal-title":"Behav Brain Res"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.physbeh.2003.09.002","article-title":"The relative playfulness of juvenile Lewis and Fischer-344 rats","volume":"80","author":"SM Siviy","year":"2003","journal-title":"Physiol Behav"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/S0031-9384(00)00374-7","article-title":"High social anxiety and low aggression in Fawn-Hooded rats","volume":"71","author":"S Kantor","year":"2000","journal-title":"Physiol Behav"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1007\/s00213-013-3337-9","article-title":"Social play behavior, ultrasonic vocalizations and their modulation by morphine and amphetamine in Wistar and Sprague-Dawley rats","volume":"231","author":"A Manduca","year":"2014","journal-title":"Psychopharmacology (Berl)"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/j.euroneuro.2014.05.009","article-title":"Strain- and context-dependent effects of the anandamide hydrolysis inhibitor URB597 on social behavior in rats","volume":"24","author":"A Manduca","year":"2014","journal-title":"Eur Neuropsychopharmacol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.bbr.2006.08.023","article-title":"Animal models of restricted repetitive behavior in autism","volume":"176","author":"MH Lewis","year":"2007","journal-title":"Behav Brain Res"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.pbb.2009.05.003","article-title":"Progestogens and estrogen influence impulsive burying and avoidant freezing behavior of naturally cycling and ovariectomized rats","volume":"93","author":"DC Llaneza","year":"2009","journal-title":"Pharmacol Biochem Behav"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.psyneuen.2007.04.003","article-title":"Attenuation of estrous cycle-dependent marble burying in female rats by acute treatment with progesterone and antidepressants","volume":"32","author":"T Schneider","year":"2007","journal-title":"Psychoneuroendocrinology"},{"issue":"Unit 8","key":"ref47","first-page":"26","article-title":"Automated three-chambered social approach task for mice","volume":"Chapter 8","author":"M Yang","year":"2011","journal-title":"Curr Protoc Neurosci"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/dev.420140405","article-title":"The ontogeny of play in rats","volume":"14","author":"J Panksepp","year":"1981","journal-title":"Dev Psychobiol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/0149-7634(84)90004-6","article-title":"Social play in juvenile rats: a decade of methodological and experimental research","volume":"8","author":"DH Thor","year":"1984","journal-title":"Neurosci Biobehav Rev"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.ejphar.2015.03.043","article-title":"Ethological concepts enhance the translational value of animal models","volume":"759","author":"SM Peters","year":"2015","journal-title":"Eur J Pharmacol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1016\/j.neubiorev.2011.03.006","article-title":"In search of the neurobiological substrates for social playfulness in mammalian brains","volume":"35","author":"SM Siviy","year":"2011","journal-title":"Neurosci Biobehav Rev"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.tips.2010.06.008","article-title":"The pleasures of play: pharmacological insights into social reward mechanisms","volume":"31","author":"V Trezza","year":"2010","journal-title":"Trends Pharmacol Sci"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.dcn.2011.05.007","article-title":"Evaluating the rewarding nature of social interactions in laboratory animals","volume":"1","author":"V Trezza","year":"2011","journal-title":"Dev Cogn Neurosci"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/dev.420220206","article-title":"Aggressive behaviors in adult rats deprived of playfighting experience as juveniles","volume":"22","author":"M Potegal","year":"1989","journal-title":"Dev Psychobiol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/0149-7634(84)90005-8","article-title":"The psychobiology of play: theoretical and methodological perspectives","volume":"8","author":"J Panksepp","year":"1984","journal-title":"Neurosci Biobehav Rev"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/j.1469-7998.1975.tb01391.x","article-title":"An investigation of playful behaviour in Rattus norvegicus and Mus musculus (Mammalia)","volume":"175","author":"TB Poole","year":"1974","journal-title":"J Zoo"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1111\/j.1365-2826.2008.01772.x","article-title":"Behavioural assays to model cognitive and affective dimensions of depression and anxiety in rats","volume":"20","author":"MD Lapiz-Bluhm","year":"2008","journal-title":"J Neuroendocrinol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0091-3057(94)90472-3","article-title":"Ethopharmacological analysis of rat behavior on the elevated plus-maze","volume":"49","author":"AP Cruz","year":"1994","journal-title":"Pharmacol Biochem Behav"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0091-3057(95)02171-X","article-title":"The influence of open arm ledges and maze experience in the elevated plus-maze","volume":"54","author":"C Fernandes","year":"1996","journal-title":"Pharmacol Biochem Behav"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0163-1047(80)91077-8","article-title":"Social deprivation and play in rats","volume":"30","author":"J Panksepp","year":"1980","journal-title":"Behav Neural Biol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.physbeh.2011.12.025","article-title":"Low sociability in BTBR T+tf\/J mice is independent of partner strain","volume":"107","author":"M Yang","year":"2012","journal-title":"Physiol Behav"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"e351","DOI":"10.1371\/journal.pone.0000351","article-title":"Affiliative behavior, ultrasonic communication and social reward are influenced by genetic variation in adolescent mice","volume":"2","author":"JB Panksepp","year":"2007","journal-title":"PLoS One"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/FBP.0b013e328343d7dd","article-title":"Age-dependent and strain-dependent influences of morphine on mouse social investigation behavior","volume":"22","author":"BC Kennedy","year":"2011","journal-title":"Behav Pharmacol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/0031-9384(94)00336-X","article-title":"Performance of four different rat strains in the autoshaping, two-object discrimination, and swim maze tests of learning and memory","volume":"57","author":"JS Andrews","year":"1995","journal-title":"Physiol Behav"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0031-9384(02)00645-5","article-title":"Rat sex and strain differences in responses to stress","volume":"75","author":"MM Faraday","year":"2002","journal-title":"Physiol Behav"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.pbb.2005.01.015","article-title":"Strain and sex alter effects of stress and nicotine on feeding, body weight, and HPA axis hormones","volume":"80","author":"MM Faraday","year":"2005","journal-title":"Pharmacol Biochem Behav"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.bbr.2014.10.039","article-title":"Strain and sex differences in brain and behaviour of adult rats: Learning and memory, anxiety and volumetric estimates","volume":"288","author":"RJ Keeley","year":"2015","journal-title":"Behav Brain Res"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.bbr.2009.07.026","article-title":"Medial prefrontal administration of MK-801 impairs T-maze discrimination reversal learning in weanling rats","volume":"205","author":"DJ Watson","year":"2009","journal-title":"Behav Brain Res"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3389\/fnbeh.2013.00097","article-title":"Interaction of genotype and environment: effect of strain and housing conditions on cognitive behavior in rodent models of schizophrenia","volume":"7","author":"KM Turner","year":"2013","journal-title":"Front Behav Neurosci"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/026988119400800302","article-title":"Differences between three rat strains in sensitivity to prepulse inhibition of an acoustic startle response: influence of apomorphine and phencyclidine pretreatment","volume":"8","author":"GB Varty","year":"1994","journal-title":"J Psychopharmacol"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0028-3908(89)90038-5","article-title":"Involvement of opioid and dopaminergic systems in isolation-induced pinning and social grooming of young rats","volume":"28","author":"RJM Niesink","year":"1989","journal-title":"Neuropharmacology"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1177\/1362361303007004002","article-title":"Social play and autistic spectrum disorders: a perspective on theory, implications and educational approaches","volume":"7","author":"R Jordan","year":"2003","journal-title":"Autism"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1177\/1362361303007002002","article-title":"Parental identification of early behavioural abnormalities in children with autistic disorder","volume":"7","author":"RL Young","year":"2003","journal-title":"Autism"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/0031-9384(83)90243-3","article-title":"Involvement of the pituitary-adrenal axis in socio-behavioral disturbances after short-term isolation","volume":"30","author":"RJ Niesink","year":"1983","journal-title":"Physiol Behav"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0031-9384(94)00385-I","article-title":"Influence of environmental factors on social play behavior of juvenile rats","volume":"58","author":"LJ Vanderschuren","year":"1995","journal-title":"Physiol Behav"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jneumeth.2014.03.001","article-title":"Reproducibility and relevance of future behavioral sciences should benefit from a cross fertilization of past recommendations and today&apos;s technology: &quot;Back to the future&quot;","volume":"234","author":"BM Spruijt","year":"2014","journal-title":"J Neurosci Methods"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0031-9384(98)00285-6","article-title":"Social behavior and social motivation in adolescent rats: role of housing conditions and partner&apos;s activity","volume":"67","author":"EI Varlinskaya","year":"1999","journal-title":"Physiol Behav"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/0091-3057(82)90445-2","article-title":"Psychomotor stimulants, social deprivation and play in juvenile rats","volume":"16","author":"WW Beatty","year":"1982","journal-title":"Pharmacol Biochem Behav"},{"key":"ref79","article-title":"Diagnostic and statistical manual of mental disorders: DSM-5","year":"2013"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.bbr.2007.11.024","article-title":"Social interactions in adolescent and adult Sprague-Dawley rats: impact of social deprivation and test context familiarity","volume":"188","author":"EI Varlinskaya","year":"2008","journal-title":"Behav Brain Res"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.beproc.2015.01.016","article-title":"Are 50-khz calls used as play signals in the playful interactions of rats? III. The effects of devocalization on play with unfamiliar partners as juveniles and as adults","volume":"113","author":"TM Kisko","year":"2015","journal-title":"Behav Processes"},{"key":"ref82","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/(SICI)1098-2302(199809)33:2<147::AID-DEV5>3.0.CO;2-J","article-title":"Mechanisms underlying the absence of the pubertal shift in the playful defense of female rats","volume":"33","author":"LK Smith","year":"1998","journal-title":"Dev Psychobiol"},{"key":"ref83","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1601-183X.2004.00071.x","article-title":"Automated apparatus for quantitation of social approach behaviors in mice","volume":"3","author":"JJ Nadler","year":"2004","journal-title":"Genes Brain Behav"},{"key":"ref84","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0014-2999(86)90051-8","article-title":"Major tranquillizers can be distinguished from minor tranquillizers on the basis of effects on marble burying and swim-induced grooming in mice","volume":"126","author":"CL Broekkamp","year":"1986","journal-title":"Eur J Pharmacol"},{"key":"ref85","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1467-9450.1987.tb00761.x","article-title":"Marble burying and spontaneous motor activity in mice: interactions over days and the effect of diazepam","volume":"28","author":"T Archer","year":"1987","journal-title":"Scand J Psychol"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0091-3057(91)90590-X","article-title":"Evaluation of marble-burying behavior as a model of anxiety","volume":"38","author":"K Njung'e","year":"1991","journal-title":"Pharmacol Biochem Behav"},{"key":"ref87","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1038\/nprot.2006.20","article-title":"Digging and marble burying in mice: simple methods for in vivo identification of biological impacts","volume":"1","author":"RM Deacon","year":"2006","journal-title":"Nat Protoc"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s00213-002-1155-6","article-title":"Do animal models of anxiety predict anxiolytic-like effects of antidepressants?","volume":"163","author":"F Borsini","year":"2002","journal-title":"Psychopharmacology (Berl)"},{"key":"ref89","first-page":"24","article-title":"Analysis of the marble burying response: marbles serve to measure digging rather than evoke burying","volume":"6","author":"I Gyertyan","year":"1995","journal-title":"Behav Pharmacol"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s00213-009-1466-y","article-title":"Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety","volume":"204","author":"A Thomas","year":"2009","journal-title":"Psychopharmacology (Berl)"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0163-1047(81)91034-7","article-title":"Tonic immobility and the dorsal immobility response in twelve species of muroid rodents","volume":"31","author":"DG Webster","year":"1981","journal-title":"Behav Neural Biol"},{"key":"ref92","article-title":"Pro-social ultrasonic communication in rats: Insights from playback studies","author":"D Seffer","year":"2014","journal-title":"J Neurosci Methods"},{"key":"ref93","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/j.1601-183X.2006.00295.x","article-title":"Social reward among juvenile mice","volume":"6","author":"JB Panksepp","year":"2007","journal-title":"Genes Brain Behav"},{"key":"ref94","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1016\/j.neubiorev.2011.05.013","article-title":"Rodent empathy and affective neuroscience","volume":"35","author":"JB Panksepp","year":"2011","journal-title":"Neurosci Biobehav Rev"},{"key":"ref95","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.tins.2013.04.009","article-title":"Toward a cross-species understanding of empathy","volume":"36","author":"J Panksepp","year":"2013","journal-title":"Trends Neurosci"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0158150","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,2]],"date-time":"2022-07-02T09:05:30Z","timestamp":1656752730000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0158150"}},"subtitle":[],"editor":[{"given":"Sergio","family":"Pellis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,6,28]]},"references-count":95,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2016,6,28]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0158150","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,28]]}}}