{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:23:22Z","timestamp":1791977002244,"version":"4.4.0"},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2016,7,14]],"date-time":"2016-07-14T00:00:00Z","timestamp":1468454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0158506","type":"journal-article","created":{"date-parts":[[2016,7,14]],"date-time":"2016-07-14T20:33:27Z","timestamp":1468528407000},"page":"e0158506","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Ventricular Volume Load Reveals the Mechanoelastic Impact of Communicating Hydrocephalus on Dynamic Cerebral Autoregulation"],"prefix":"10.1371","volume":"11","author":[{"given":"Christina","family":"Haubrich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Czosnyka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Diehl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Smielewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zofia","family":"Czosnyka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,7,14]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1093\/brain\/awh131","article-title":"Pattern of white matter regional cerebral blood flow and autoregulation in normal pressure hydrocephalus","volume":"127","author":"S Momjian","year":"2004","journal-title":"Brain"},{"key":"ref2","first-page":"59","article-title":"Communicating hydrocephalus: the biomechanics of progressive ventricular enlargement revisited","volume":"81","author":"A Pena","year":"2002","journal-title":"Acta Neurochir Suppl"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1034\/j.1600-0404.2001.00092.x","article-title":"Normal pressure hydrocephalus and cerebral blood flow: a review","volume":"104","author":"BK Owler","year":"2001","journal-title":"Acta Neurol Scand"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s007010200033","article-title":"Quantitative local cerebral blood flow change after cerebrospinalfluid removal in patients with normal pressure hydrocephalus measured by a double injection method with Nisopropyl-p-[123I] iodoamphetamine","volume":"144","author":"K Mori","year":"2002","journal-title":"Acta Neurochir (Wien)"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1136\/jnnp.74.4.479","article-title":"Is a combination of Tc-SPECT or perfusion weighted magnetic resonance imaging with spinal tap test helpful in the diagnosis of normal pressure hydrocephalus?","volume":"74","author":"F Hertel","year":"2003","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref6","first-page":"526","article-title":"Cerebral autoregulation among patients with symptoms of hydrocephalus","volume":"50","author":"ZH Czosnyka","year":"2002","journal-title":"Neurosurgery"},{"issue":"10","key":"ref7","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1161\/STROKEAHA.107.485847","article-title":"Is there a direct link between cerebrovascular activity and CSF pressure-volume compensation?","volume":"38","author":"C Haubrich","year":"2007","journal-title":"Stroke"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1046\/j.1351-5101.2003.00698.x","article-title":"Differences in cerebrospinal fluid dynamics do not affect the levels of biochemical markers in ventricular CSF from patients with aqueductal stenosis and idiopathic normal pressure hydrocephalus","volume":"11","author":"M Tisell","year":"2004","journal-title":"European Journal of Neurology"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1136\/jnnp.60.5.549","article-title":"Testing of cerebrospinal compensatory reserve in shunted and non-shunted patients: a guide to interpretation based on observational study","volume":"60","author":"M Czosnyka","year":"1996","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref10","first-page":"p5","article-title":"Observations on the structure and function of the nervous system","author":"A Monro","year":"1823"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1212\/WNL.56.12.1746","article-title":"The Monro\u2013Kellie hypothesis: Applications in CSF volume depletion","volume":"56","author":"B Mokri","year":"2001","journal-title":"Neurology"},{"key":"ref12","first-page":"84","article-title":"An account of the appearances observed in the dissection of two of the three individuals presumed to have perished in the storm of the 3rd, and whose bodies were discovered in the vicinity of Leith on the morning of the 4th November 1821 with some reflections on the pathology of the brain","volume":"1","author":"G Kellie","year":"1824","journal-title":"Trans Med Chir Sci"},{"issue":"3","key":"ref13","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1227\/01.NEU.0000338434.59141.89","article-title":"Index of cerebrospinal compensatory reserve in hydrocephalus","volume":"64","author":"DJ Kim","year":"2009","journal-title":"Neurosurgery"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"R51","DOI":"10.1088\/0967-3334\/25\/5\/R01","article-title":"Cerebrospinal Fluid Dynamics","volume":"25","author":"M Czosnyka","year":"2004","journal-title":"Physiol. Meas"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1136\/jnnp.2003.033126","article-title":"Monitoring and interpretation of intracranial pressure","volume":"75","author":"M Czosnyka","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"4","key":"ref16","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1159\/000131675","article-title":"Value of overnight monitoring of intracranial pressure in hydrocephalic children","volume":"44","author":"MU Schuhmann","year":"2008","journal-title":"Pediatr Neurosurg"},{"key":"ref17","article-title":"Doppler Flow Velocity and Intracranial Pressure: Responses to Short-Term Mild Hypocapnia Help to Assess the Pressure-Volume Relationship After Head Injury","author":"C Haubrich","year":"2013","journal-title":"Ultrasound Med Biol"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.medengphy.2014.11.009","article-title":"Increasing ICP dampens the transfer of respiratory waves to the brain and cerebral arteries in patients with traumatic brain injury","volume":"37","author":"C Haubrich","year":"2015","journal-title":"Medical Engineering & Physics"},{"issue":"5","key":"ref19","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s00701-005-0510-x","article-title":"Predicting the response of intracranial pressure to moderate hyperventilation","volume":"147","author":"LA Steiner","year":"2005","journal-title":"Acta Neurochirurgica"},{"key":"ref20","first-page":"102","article-title":"Severe Closed Head Injury","author":"IR Piper","year":"1997"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/BF02267598","article-title":"Spontaneous blood pressure oscillations and cerebral autoregulation","volume":"8","author":"RR Diehl","year":"1998","journal-title":"Clin Auton Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1097\/00003246-200101000-00031","article-title":"Cerebral autoregulation testing after aneurysmal subarachnoid hemorrhage: The phase relationship between arterial blood pressure and cerebral blood flow velocity","volume":"29","author":"EW Lang","year":"2001","journal-title":"Crit Care Med"},{"key":"ref23","first-page":"187","article-title":"The physics of the cranial cavity, hydrocephalus and normal pressure hydrocephalus: mechanical interpretation and mathematical model","volume":"5","author":"S Hakim","year":"1970","journal-title":"Surg Neurol"},{"key":"ref24","first-page":"31","article-title":"Association of deep white matter infarction with chronic communicating hydrocephalus: implications regarding the possible origin of normal pressure hydrocephalus","volume":"12","author":"WG Bradley","year":"1991","journal-title":"AJNR"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1161\/01.STR.27.1.24","article-title":"Vascular risk factors and arteriosclerotic disease in idiopathic normal pressure hydrocephalus of the elderly","volume":"27","author":"JK Krauss","year":"1996","journal-title":"Stroke"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"644","DOI":"10.3171\/jns.1969.31.6.0644","article-title":"Pre- and postoperative evaluation of cerebral blood flow in low pressure hydrocephalus","volume":"31","author":"TV Greitz","year":"1969","journal-title":"J Neurosurg"},{"key":"ref27","article-title":"Hydrocephalus","author":"J Ekstedt","year":"1984"},{"key":"ref28","first-page":"1665","article-title":"Normal Pressure Hydrocephalus: Vascular White Matter Changes on MR Images Must Not Exclude Patients from Shunt Surgery","volume":"22","author":"M Tullberg","year":"2001","journal-title":"AJNR"},{"key":"ref29","first-page":"1574","article-title":"Vascular Compliance in Normal Pressure Hydrocephalus","volume":"21","author":"GA Bateman","year":"2000","journal-title":"AJNR"},{"key":"ref30","first-page":"1","article-title":"Finite element analysis of periventricular lucency in hydrocephalus: extravasation or transependymal CSF absorption?","volume":"14","author":"H Kim","year":"2015","journal-title":"J Neurosurg"},{"issue":"3","key":"ref31","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1034\/j.1600-0404.2003.00210.x","article-title":"M-wave analysis and passive tilt in patients with different degrees of carotid artery disease","volume":"109","author":"C Haubrich","year":"2004","journal-title":"Acta neurol scand"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1161\/01.STR.0000080936.36601.34","article-title":"Dynamic autoregulation testing in patients with middle cerebral artery stenosis","volume":"34","author":"C Haubrich","year":"2003","journal-title":"Stroke"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1161\/01.STR.0000127533.46914.31","article-title":"Effect of carotid endarterectomy or stenting on impairment of dynamic cerebral autoregulation","volume":"35","author":"M Reinhard","year":"2004","journal-title":"Stroke"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/3-211-32318-X_62","article-title":"Non-invasive measurement of intracranial compliance using cine MRI in normal pressure hydrocephalus","volume":"95","author":"M Mase","year":"2006","journal-title":"Acta Neurochir Suppl"},{"issue":"3","key":"ref35","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s00234-011-0871-1","article-title":"Alteration of brain viscoelasticity after shunt treatment in normal pressure hydrocephalus","volume":"54","author":"FB Freimann","year":"2012","journal-title":"Neuroradiology"},{"key":"ref36","first-page":"41","article-title":"W Hydrocephalus detection using intrinsically-activated MRE Proc","volume":"19","author":"KD Paulsen","year":"2011","journal-title":"Intl. Soc. Mag. Reson. Med"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0158506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T13:14:53Z","timestamp":1540041293000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0158506"}},"subtitle":[],"editor":[{"given":"Felix","family":"Schlachetzki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,7,14]]},"references-count":36,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2016,7,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0158506","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,14]]}}}