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Shanghai Daily. December 17, 2010. Available at: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.china.org.cn\/china\/2010-12\/17\/content_21563175.htm\" xlink:type=\"simple\">http:\/\/www.china.org.cn\/china\/2010-12\/17\/content_21563175.htm<\/ext-link>. 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