{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T15:45:49Z","timestamp":1751384749321,"version":"3.37.3"},"reference-count":23,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2016,8,16]],"date-time":"2016-08-16T00:00:00Z","timestamp":1471305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81371499"],"award-info":[{"award-number":["81371499"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30971586"],"award-info":[{"award-number":["30971586"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0160265","type":"journal-article","created":{"date-parts":[[2016,8,16]],"date-time":"2016-08-16T17:42:11Z","timestamp":1471369331000},"page":"e0160265","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Investigation of a Possible Role for the Histidine Decarboxylase Gene in Tourette Syndrome in the Chinese Han Population: A Family-Based Study"],"prefix":"10.1371","volume":"11","author":[{"given":"He","family":"Dong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenmiao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meixin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Longqiang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ru","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiguo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2016,8,16]]},"reference":[{"issue":"Pt 3","key":"ref1","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1093\/brain\/123.3.425","article-title":"Tourette syndrome, associated conditions and the complexities of treatment","volume":"123","author":"MM Robertson","year":"2000","journal-title":"Brain"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1002\/mds.26279","article-title":"GDNF gene is associated with tourette syndrome in a family study","volume":"30","author":"I Huertas-Fernandez","year":"2015","journal-title":"Mov Disord"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1177\/08830738060210081001","article-title":"Tourette syndrome: the self under siege","volume":"21","author":"JF Leckman","year":"2006","journal-title":"J Child Neurol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1002\/mds.22504","article-title":"Immunopathogenic mechanisms in tourette syndrome: A critical review","volume":"24","author":"D Martino","year":"2009","journal-title":"Mov Disord"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.2217\/pgs.10.160","article-title":"Blood gene expression correlated with tic severity in medicated and unmedicated patients with Tourette Syndrome","volume":"11","author":"IH Liao","year":"2010","journal-title":"Pharmacogenomics"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1097\/WCO.0000000000000119","article-title":"Neurobehavioral aspects, pathophysiology, and management of Tourette syndrome","volume":"27","author":"DR Shprecher","year":"2014","journal-title":"Curr Opin Neurol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1056\/NEJMoa0907006","article-title":"L-histidine decarboxylase and Tourette's syndrome","volume":"362","author":"AG Ercan-Sencicek","year":"2010","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1093\/nar\/28.14.2627","article-title":"The mouse L-histidine decarboxylase gene: structure and transcriptional regulation by CpG methylation in the promoter region","volume":"28","author":"S Suzuki-Ishigaki","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.tins.2014.12.008","article-title":"The human histaminergic system in neuropsychiatric disorders","volume":"38","author":"L Shan","year":"2015","journal-title":"Trends Neurosci"},{"key":"ref10","article-title":"Histamine and histamine receptors in Tourette syndrome and other neuropsychiatric conditions","author":"M Rapanelli","year":"2015","journal-title":"Neuropharmacology"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.neuron.2013.10.052","article-title":"Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice","volume":"81","author":"L Castellan Baldan","year":"2014","journal-title":"Neuron"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1136\/jmedgenet-2013-101637","article-title":"Support of the histaminergic hypothesis in Tourette syndrome: association of the histamine decarboxylase gene in a large sample of families","volume":"50","author":"I Karagiannidis","year":"2013","journal-title":"J Med Genet"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.jpsychores.2008.04.010","article-title":"The influence of contextual factors on tic expression in Tourette's syndrome: a review","volume":"65","author":"CA Conelea","year":"2008","journal-title":"J Psychosom Res"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1212\/WNL.42.3.652","article-title":"Relationship of birth weight to the phenotypic expression of Gilles de la Tourette's syndrome in monozygotic twins","volume":"42","author":"TM Hyde","year":"1992","journal-title":"Neurology"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"12387","DOI":"10.1523\/JNEUROSCI.0150-11.2011","article-title":"Neurobiology of tourette syndrome: current status and need for further investigation","volume":"31","author":"RJ Felling","year":"2011","journal-title":"J Neurosci"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/nn.2121","article-title":"Thinning of sensorimotor cortices in children with Tourette syndrome","volume":"11","author":"ER Sowell","year":"2008","journal-title":"Nat Neurosci"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/WCO.0b013e328344648c","article-title":"Recent advances in Tourette syndrome","volume":"24","author":"M Bloch","year":"2011","journal-title":"Curr Opin Neurol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.tips.2011.01.003","article-title":"Histamine receptors in the CNS as targets for therapeutic intervention","volume":"32","author":"MB Passani","year":"2011","journal-title":"Trends Pharmacol Sci"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0014-5793(01)02663-1","article-title":"Mice lacking histidine decarboxylase exhibit abnormal mast cells","volume":"502","author":"H Ohtsu","year":"2001","journal-title":"FEBS Lett"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1101\/lm.67603","article-title":"Histidine-decarboxylase knockout mice show deficient nonreinforced episodic object memory, improved negatively reinforced water-maze performance, and increased neo- and ventro-striatal dopamine turnover","volume":"10","author":"E Dere","year":"2003","journal-title":"Learn Mem"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.biopsych.2011.09.034","article-title":"Rare copy number variants in tourette syndrome disrupt genes in histaminergic pathways and overlap with autism","volume":"71","author":"TV Fernandez","year":"2012","journal-title":"Biol Psychiatry"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/ajmg.b.32003","article-title":"Mutation screening of the HDC gene in Chinese Han patients with Tourette syndrome","volume":"159B","author":"J Lei","year":"2012","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ygeno.2011.04.006","article-title":"Gene set analysis of genome-wide association studies: methodological issues and perspectives","volume":"98","author":"L Wang","year":"2011","journal-title":"Genomics"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0160265","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T06:22:15Z","timestamp":1589005335000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0160265"}},"subtitle":[],"editor":[{"given":"Ornit","family":"Chiba-Falek","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,8,16]]},"references-count":23,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2016,8,16]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0160265","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2016,8,16]]}}}