{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T04:10:40Z","timestamp":1774671040432,"version":"3.50.1"},"reference-count":92,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T00:00:00Z","timestamp":1470268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"March of Dimes Foundation (US)","award":["21-FY16-4341"],"award-info":[{"award-number":["21-FY16-4341"]}]},{"name":"Jane and Dan Olsson Foundations"},{"name":"Vetenskapsr\u00e5det (SE)","award":["VR-02559"],"award-info":[{"award-number":["VR-02559"]}]},{"DOI":"10.13039\/501100005416","name":"Research Council of Norway","doi-asserted-by":"crossref","award":["FRIMEDBIO-249779"],"award-info":[{"award-number":["FRIMEDBIO-249779"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0160335","type":"journal-article","created":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T17:42:39Z","timestamp":1470332559000},"page":"e0160335","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":22,"title":["Literature-Informed Analysis of a Genome-Wide Association Study of Gestational Age in Norwegian Women and Children Suggests Involvement of Inflammatory Pathways"],"prefix":"10.1371","volume":"11","author":[{"given":"Jonas","family":"Bacelis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julius","family":"Juodakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verena","family":"Sengpiel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ge","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronny","family":"Myhre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis J.","family":"Muglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Staffan","family":"Nilsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Jacobsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2016,8,4]]},"reference":[{"issue":"6","key":"ref1","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1056\/NEJMra0904308","article-title":"The enigma of spontaneous preterm birth","volume":"362","author":"LJ Muglia","year":"2010","journal-title":"N Engl J Med"},{"issue":"216","key":"ref2","first-page":"1","article-title":"Births in the United States, 2014","volume":"2015","author":"JA Martin","journal-title":"NCHS data brief"},{"issue":"9832","key":"ref3","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1016\/S0140-6736(12)60820-4","article-title":"National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications","volume":"379","author":"H Blencowe","year":"2012","journal-title":"Lancet"},{"key":"ref4","unstructured":"In: Behrman RE, Butler AS, editors. Preterm Birth: Causes, Consequences, and Prevention. The National Academies Collection: Reports funded by National Institutes of Health. Washington (DC)2007."},{"issue":"9607","key":"ref5","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/S0140-6736(08)60108-7","article-title":"Primary, secondary, and tertiary interventions to reduce the morbidity and mortality of preterm birth","volume":"371","author":"JD Iams","year":"2008","journal-title":"Lancet"},{"issue":"7","key":"ref6","doi-asserted-by":"crossref","first-page":"e101682","DOI":"10.1371\/journal.pone.0101682","article-title":"Antenatal maternal emotional distress and duration of pregnancy","volume":"9","author":"M Lukasse","year":"2014","journal-title":"PLOS One"},{"issue":"7","key":"ref7","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s00439-015-1558-1","article-title":"The heritability of gestational age in a two-million member cohort: implications for spontaneous preterm birth","volume":"134","author":"W Wu","year":"2015","journal-title":"Hum Genet"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1471-0528.2000.tb13234.x","article-title":"Genetic influence on birthweight and gestational length determined by studies in offspring of twins","volume":"107","author":"B Clausson","year":"2000","journal-title":"BJOG"},{"issue":"3","key":"ref9","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ygeno.2012.12.005","article-title":"Pathway-based genetic analysis of preterm birth","volume":"101","author":"A Uzun","year":"2013","journal-title":"Genomics"},{"issue":"3","key":"ref10","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/gepi.21887","article-title":"A genome-wide association study of early spontaneous preterm delivery","volume":"39","author":"H Zhang","year":"2015","journal-title":"Genet Epidemiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ejogrb.2014.02.035","article-title":"Gestational age-dependent risk factors for preterm birth: associations with maternal education and age early in gestation","volume":"176","author":"N Auger","year":"2014","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"5","key":"ref12","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1093\/ije\/dyl170","article-title":"Cohort profile: the Norwegian Mother and Child Cohort Study (MoBa)","volume":"35","author":"P Magnus","year":"2006","journal-title":"Int J Epidemiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/03009742.1998.11720780","article-title":"The Medical Birth Registry of Norway; a source for epidemiological and clinical research","volume":"107","author":"LM Irgens","year":"1998","journal-title":"Scand J Rheumatol Suppl"},{"issue":"4","key":"ref14","doi-asserted-by":"crossref","first-page":"e61781","DOI":"10.1371\/journal.pone.0061781","article-title":"X-chromosomal maternal and fetal SNPs and the risk of spontaneous preterm delivery in a Danish\/Norwegian genome-wide association study","volume":"8","author":"S Myking","year":"2013","journal-title":"PLOS One"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13742-015-0047-8","article-title":"Second-generation PLINK: rising to the challenge of larger and richer datasets","volume":"4","author":"CC Chang","year":"2015","journal-title":"GigaScience"},{"issue":"4","key":"ref16","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1038\/ng.1109","article-title":"A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population","volume":"44","author":"C Tanikawa","year":"2012","journal-title":"Nat Genet"},{"issue":"5","key":"ref17","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/pr.2012.112","article-title":"No observed association for mitochondrial SNPs with preterm delivery and related outcomes","volume":"72","author":"BW Alleman","year":"2012","journal-title":"Pediatr Res"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"D1079","DOI":"10.1093\/nar\/gku1071","article-title":"<ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/Genenames.org\" xlink:type=\"simple\">Genenames.org<\/ext-link>: the HGNC resources in 2015","volume":"43","author":"KA Gray","year":"2015","journal-title":"Nucleic Acids Res"},{"issue":"13","key":"ref19","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1093\/bioinformatics\/bts191","article-title":"INRICH: interval-based enrichment analysis for genome-wide association studies","volume":"28","author":"PH Lee","year":"2012","journal-title":"Bioinformatics"},{"issue":"D1","key":"ref20","doi-asserted-by":"crossref","first-page":"D930","DOI":"10.1093\/nar\/gkr917","article-title":"HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants","volume":"40","author":"LD Ward","year":"2012","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"ref21","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1095\/biolreprod.113.110056","article-title":"NOD1 and NOD2 regulate proinflammatory and prolabor mediators in human fetal membranes and myometrium via nuclear factor-kappa B","volume":"89","author":"M Lappas","year":"2013","journal-title":"Biol Reprod"},{"issue":"10","key":"ref22","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1038\/ng.2756","article-title":"Systematic identification of trans eQTLs as putative drivers of known disease associations","volume":"45","author":"HJ Westra","year":"2013","journal-title":"Nat Genet"},{"issue":"5","key":"ref23","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1096\/fj.13-247783","article-title":"Activator protein 1 is a key terminal mediator of inflammation-induced preterm labor in mice","volume":"28","author":"DA MacIntyre","year":"2014","journal-title":"FASEB J"},{"issue":"12","key":"ref24","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1084\/jem.20021552","article-title":"The PAAD\/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways","volume":"196","author":"C Stehlik","year":"2002","journal-title":"J Exp Med"},{"issue":"8","key":"ref25","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1038\/gene.2009.59","article-title":"A population genetics study of the familial Mediterranean fever gene: evidence of balancing selection under an overdominance regime","volume":"10","author":"M Fumagalli","year":"2009","journal-title":"Genes Immun"},{"issue":"5","key":"ref26","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1542\/peds.2008-1222","article-title":"Differential patterns of 27 cord blood immune biomarkers across gestational age","volume":"123","author":"N Matoba","year":"2009","journal-title":"Pediatrics"},{"issue":"5","key":"ref27","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/ni.3143","article-title":"The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity","volume":"16","author":"ZG Ramirez-Ortiz","year":"2015","journal-title":"Nat Immunol"},{"issue":"4","key":"ref28","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1600-0897.2004.00162.x","article-title":"IFN-gamma-mediated inhibition of COX-2 expression in the placenta from term and preterm labor pregnancies","volume":"51","author":"N Hanna","year":"2004","journal-title":"Am J Reprod Immunol"},{"issue":"9","key":"ref29","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1080\/00016340701515423","article-title":"Mid-pregnancy maternal plasma levels of interleukin 2, 6, and 12, tumor necrosis factor-alpha, interferon-gamma, and granulocyte-macrophage colony-stimulating factor and spontaneous preterm delivery","volume":"86","author":"AE Curry","year":"2007","journal-title":"Acta Obstet Gynecol Scand"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ejogrb.2015.04.003","article-title":"Association between maternal tumor necrosis factor-alpha G308A polymorphism and interferon-gamma A874T polymorphism and risk of preterm birth: a meta-analysis","volume":"190","author":"Y Liu","year":"2015","journal-title":"Eur J Obstet Gyn R B"},{"issue":"8","key":"ref31","doi-asserted-by":"crossref","first-page":"e103434","DOI":"10.1371\/journal.pone.0103434","article-title":"Human cathelicidin production by the cervix","volume":"9","author":"L Frew","year":"2014","journal-title":"PLOS One"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jri.2014.10.002","article-title":"Human cathelicidin antimicrobial protein 18 (hCAP18\/LL-37) is increased in foetal membranes and myometrium after spontaneous labour and delivery","volume":"107","author":"R Lim","year":"2015","journal-title":"J Reprod Immunol"},{"issue":"6235","key":"ref33","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1126\/science.1262110","article-title":"Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans","volume":"348","author":"GT Consortium","year":"2015","journal-title":"Science"},{"issue":"11","key":"ref34","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/sj.jp.7211806","article-title":"Maternal and fetal variation in genes of cholesterol metabolism is associated with preterm delivery","volume":"27","author":"KM Steffen","year":"2007","journal-title":"J Perinatol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.micpath.2013.05.006","article-title":"ABC-cassette transporter 1 (ABCA1) expression in epithelial cells in Chlamydia pneumoniae infection","volume":"61\u201362","author":"JT Korhonen","year":"2013","journal-title":"Microb Pathog"},{"issue":"21","key":"ref36","doi-asserted-by":"crossref","first-page":"16369","DOI":"10.1074\/jbc.M109.061424","article-title":"Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation","volume":"285","author":"K Okuhira","year":"2010","journal-title":"J Biol Chem"},{"issue":"3","key":"ref37","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1182\/blood-2005-12-5046","article-title":"The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation","volume":"108","author":"A Blumenthal","year":"2006","journal-title":"Blood"},{"issue":"1","key":"ref38","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.joen.2013.09.011","article-title":"Lipopolysaccharide enhances Wnt5a expression through toll-like receptor 4, myeloid differentiating factor 88, phosphatidylinositol 3-OH kinase\/AKT and nuclear factor kappa B pathways in human dental pulp stem cells","volume":"40","author":"W He","year":"2014","journal-title":"J Endod"},{"issue":"5","key":"ref39","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1165\/rcmb.2008-0201OC","article-title":"WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis","volume":"41","author":"LJ Vuga","year":"2009","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"7359","key":"ref40","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1136\/bmj.325.7359.301","article-title":"Accuracy of cervicovaginal fetal fibronectin test in predicting risk of spontaneous preterm birth: systematic review","volume":"325","author":"H Honest","year":"2002","journal-title":"BMJ"},{"issue":"8","key":"ref41","doi-asserted-by":"crossref","first-page":"e1000949","DOI":"10.1371\/journal.ppat.1000949","article-title":"The battle for iron between bacterial pathogens and their vertebrate hosts","volume":"6","author":"EP Skaar","year":"2010","journal-title":"PLOS Pathog"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1471-2334-5-55","article-title":"Subclinical iron deficiency is a strong predictor of bacterial vaginosis in early pregnancy","volume":"5","author":"H Verstraelen","year":"2005","journal-title":"BMC Infect Dis"},{"issue":"9","key":"ref43","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1002\/pd.1981","article-title":"Second trimester amniotic fluid transferrin and uric acid predict infant birth outcomes","volume":"28","author":"T Gao","year":"2008","journal-title":"Prenat Diagn"},{"issue":"1","key":"ref44","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.diabet.2009.06.010","article-title":"Association of increased maternal ferritin levels with gestational diabetes and intra-uterine growth retardation","volume":"36","author":"V Soubasi","year":"2010","journal-title":"Diabetes Metab"},{"issue":"1","key":"ref45","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1083\/jcb.200912087","article-title":"The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation","volume":"190","author":"Z Kuang","year":"2010","journal-title":"J Cell Biol"},{"key":"ref46","first-page":"10","article-title":"Spontaneous preterm labor is associated with an increase in the proinflammatory signal transducer TLR4 receptor on maternal blood monocytes","author":"E Pawelczyk","year":"2010","journal-title":"BMC Pregnancy Childbirth"},{"issue":"4","key":"ref47","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/molehr\/gap106","article-title":"Role of Toll-like receptor 4 in inflammation-induced preterm delivery","volume":"16","author":"L Li","year":"2010","journal-title":"Mol Hum Reprod"},{"issue":"5","key":"ref48","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1093\/molehr\/8.5.494","article-title":"A polymorphism in the matrix metalloproteinase-9 promoter is associated with increased risk of preterm premature rupture of membranes in African Americans","volume":"8","author":"PE Ferrand","year":"2002","journal-title":"Mol Hum Reprod"},{"issue":"2","key":"ref49","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/molehr\/gan078","article-title":"Proinflammatory cytokine polymorphisms and the risk of preterm birth and low birthweight in a Japanese population","volume":"15","author":"F Sata","year":"2009","journal-title":"Mol Hum Reprod"},{"issue":"1","key":"ref50","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1067\/mob.2002.122407","article-title":"Polymorphism in the interleukin-1 gene complex and spontaneous preterm delivery","volume":"187","author":"MR Genc","year":"2002","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"ref51","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0165-5728(95)00140-9","article-title":"Interferon regulatory factor-2 physically interacts with NF-kappa B in vitro and inhibits NF-kappa B induction of major histocompatibility class I and beta 2-microglobulin gene expression in transfected human neuroblastoma cells","volume":"63","author":"PD Drew","year":"1995","journal-title":"J Neuroimmunol"},{"issue":"4","key":"ref52","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.4049\/jimmunol.176.4.2455","article-title":"Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37","volume":"176","author":"N Mookherjee","year":"2006","journal-title":"J Immunol"},{"issue":"1","key":"ref53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/pro.2185","article-title":"Structure and function of the SPRY\/B30.2 domain proteins involved in innate immunity","volume":"22","author":"AA D'Cruz","year":"2013","journal-title":"Protein Sci"},{"issue":"6","key":"ref54","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1095\/biolreprod.107.063743","article-title":"Matrix metalloproteinase 9 (MMP9) expression in preeclamptic decidua and MMP9 induction by tumor necrosis factor alpha and interleukin 1 beta in human first trimester decidual cells","volume":"78","author":"CJ Lockwood","year":"2008","journal-title":"Biol Reprod"},{"issue":"2","key":"ref55","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.4049\/jimmunol.1000289","article-title":"Viral infection of the placenta leads to fetal inflammation and sensitization to bacterial products predisposing to preterm labor","volume":"185","author":"I Cardenas","year":"2010","journal-title":"J Immunol"},{"issue":"3","key":"ref56","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/aji.12355","article-title":"Viral infections during pregnancy","volume":"73","author":"M Silasi","year":"2015","journal-title":"Am J Reprod Immunol"},{"issue":"22","key":"ref57","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1152\/physiolgenomics.00112.2013","article-title":"RNA viruses and microRNAs: challenging discoveries for the 21st century","volume":"45","author":"G Swaminathan","year":"2013","journal-title":"Physiol Genomics"},{"issue":"3","key":"ref58","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.jhep.2008.06.010","article-title":"Regulation of the hepatitis C virus genome replication by miR-199a","volume":"50","author":"Y Murakami","year":"2009","journal-title":"J Hepatol"},{"issue":"15","key":"ref59","doi-asserted-by":"crossref","first-page":"9556","DOI":"10.1128\/JVI.79.15.9556-9565.2005","article-title":"Suppression of RNA interference by adenovirus virus-associated RNA","volume":"79","author":"MG Andersson","year":"2005","journal-title":"J Virol"},{"issue":"7468","key":"ref60","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1038\/nature12531","article-title":"Transcriptome and genome sequencing uncovers functional variation in humans","volume":"501","author":"T Lappalainen","year":"2013","journal-title":"Nature"},{"issue":"2","key":"ref61","doi-asserted-by":"crossref","first-page":"R55","DOI":"10.1530\/REP-12-0103","article-title":"NODAL signaling components regulate essential events in the establishment of pregnancy","volume":"145","author":"CB Park","year":"2013","journal-title":"Reproduction"},{"issue":"3","key":"ref62","doi-asserted-by":"crossref","first-page":"330","DOI":"10.3109\/10641950902968684","article-title":"Soluble endoglin for the prediction of preeclampsia in a high risk cohort","volume":"29","author":"SE Maynard","year":"2010","journal-title":"Hypertens Pregnancy"},{"issue":"9","key":"ref63","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1038\/nm913","article-title":"Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities","volume":"9","author":"M Shichiri","year":"2003","journal-title":"Nat Med"},{"issue":"1","key":"ref64","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ejogrb.2012.10.032","article-title":"Association of low maternal levels of salusins with gestational diabetes mellitus and with small-for-gestational-age fetuses","volume":"167","author":"E Celik","year":"2013","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"12","key":"ref65","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1038\/nm.3012","article-title":"Mechanisms of implantation: strategies for successful pregnancy","volume":"18","author":"J Cha","year":"2012","journal-title":"Nat Med"},{"issue":"2","key":"ref66","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.biocel.2009.10.002","article-title":"HIF-1beta determines ABCA1 expression under hypoxia in human macrophages","volume":"42","author":"P Ugocsai","year":"2010","journal-title":"Int J Biochem Cell Biol"},{"issue":"7452","key":"ref67","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/nature12166","article-title":"Control of angiogenesis by AIBP-mediated cholesterol efflux","volume":"498","author":"L Fang","year":"2013","journal-title":"Nature"},{"issue":"2","key":"ref68","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.celrep.2014.06.027","article-title":"Appropriate crypt formation in the uterus for embryo homing and implantation requires Wnt5a-ROR signaling","volume":"8","author":"J Cha","year":"2014","journal-title":"Cell reports"},{"issue":"10","key":"ref69","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1161\/ATVBAHA.109.190892","article-title":"PYK2\/PDZ-RhoGEF links Ca2+ signaling to RhoA","volume":"29","author":"Z Ying","year":"2009","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"9","key":"ref70","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1097\/HJH.0000000000000251","article-title":"Fetal and maternal angiotensin (1\u20137) are associated with preterm birth","volume":"32","author":"YP Chen","year":"2014","journal-title":"J Hypertens"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1477-7827-6-1","article-title":"Expression of RHOGTPase regulators in human myometrium","volume":"6","author":"M O'Brien","year":"2008","journal-title":"Reprod Biol Endocrinol"},{"issue":"8","key":"ref72","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s00439-013-1304-5","article-title":"Maternal coding variants in complement receptor 1 and spontaneous idiopathic preterm birth","volume":"132","author":"JJ McElroy","year":"2013","journal-title":"Hum Genet"},{"issue":"3\u20134","key":"ref73","first-page":"e137","article-title":"Regulation of trophoblast invasion: the role of matrix metalloproteinases","volume":"5","author":"JY Zhu","year":"2012","journal-title":"Rev Obstet Gynecol"},{"issue":"1\u20132","key":"ref74","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0303-7207(01)00687-6","article-title":"Regulation of trophoblast invasion: from normal implantation to pre-eclampsia","volume":"187","author":"D Goldman-Wohl","year":"2002","journal-title":"Mol Cell Endocrinol"},{"issue":"6198","key":"ref75","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1126\/science.1251816","article-title":"Preterm labor: one syndrome, many causes","volume":"345","author":"R Romero","year":"2014","journal-title":"Science"},{"issue":"5","key":"ref76","doi-asserted-by":"crossref","first-page":"431 e1","DOI":"10.1016\/j.ajog.2010.03.026","article-title":"Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes","volume":"202","author":"R Romero","year":"2010","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"ref77","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/sj.jhh.1002110","article-title":"Interaction between GNB3 C825T and ACE I\/D polymorphisms in essential hypertension in Koreans","volume":"21","author":"Y Bae","year":"2007","journal-title":"J Hum Hypertens"},{"issue":"3","key":"ref78","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.preghy.2012.04.082","article-title":"OS081. Novel KCNQ3\/KCNE5 isoform protein and mRNA expression in first trimester human placentae","volume":"2","author":"HD Mistry","year":"2012","journal-title":"Pregnancy Hypertens"},{"issue":"3","key":"ref79","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1161\/HYPERTENSIONAHA.111.173740","article-title":"Novel expression and regulation of voltage-dependent potassium channels in placentas from women with preeclampsia","volume":"58","author":"HD Mistry","year":"2011","journal-title":"Hypertension"},{"issue":"2","key":"ref80","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1447-0756.1995.tb01092.x","article-title":"Biochemical events in cervical ripening dilatation during pregnancy and parturition","volume":"21","author":"RG Osmers","year":"1995","journal-title":"J Obstet Gynaecol (Tokyo 1995)"},{"issue":"1","key":"ref81","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1093\/humrep\/del360","article-title":"WNT4 deficiency\u2014a clinical phenotype distinct from the classic Mayer-Rokitansky-Kuster-Hauser syndrome: a case report","volume":"22","author":"A Biason-Lauber","year":"2007","journal-title":"Hum Reprod"},{"issue":"3","key":"ref82","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1210\/jc.2007-2023","article-title":"Identification and functional analysis of a new WNT4 gene mutation among 28 adolescent girls with primary amenorrhea and mullerian duct abnormalities: a French collaborative study","volume":"93","author":"P Philibert","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"ref83","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.theriogenology.2011.03.022","article-title":"Gene expression of WNTs, beta-catenin and E-cadherin during the periimplantation period of pregnancy in pigs\u2014involvement of steroid hormones","volume":"76","author":"J Kiewisz","year":"2011","journal-title":"Theriogenology"},{"issue":"1","key":"ref84","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1080\/09513590802288291","article-title":"Mayer-Rokitansky-Kuster-Hauser syndrome: recent clinical and genetic findings","volume":"25","author":"C Sultan","year":"2009","journal-title":"Gynecol Endocrinol"},{"issue":"10","key":"ref85","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1111\/1471-0528.13339","article-title":"Pregnancy and perinatal outcomes in women with polycystic ovary syndrome and twin births: a population-based cohort study","volume":"122","author":"TS Lovvik","year":"2015","journal-title":"BJOG"},{"issue":"8","key":"ref86","doi-asserted-by":"crossref","first-page":"e1001865","DOI":"10.1371\/journal.pmed.1001865","article-title":"Assessing the Causal Relationship of Maternal Height on Birth Size and Gestational Age at Birth: A Mendelian Randomization Analysis","volume":"12","author":"G Zhang","year":"2015","journal-title":"PLOS Med"},{"issue":"4","key":"ref87","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1095\/biolreprod.106.051912","article-title":"SP1 and SP3 mediate progesterone-dependent induction of the 17beta hydroxysteroid dehydrogenase type 2 gene in human endometrium","volume":"75","author":"YH Cheng","year":"2006","journal-title":"Biol Reprod"},{"issue":"9","key":"ref88","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1177\/1933719112438970","article-title":"The A118G single-nucleotide polymorphism of human mu-opioid receptor gene and use of labor analgesia","volume":"19","author":"FD Pettersson","year":"2012","journal-title":"Reprod Sci"},{"issue":"4","key":"ref89","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1095\/biolreprod59.4.925","article-title":"Expression of opioid receptors and ligands in pregnant mouse uterus and placenta","volume":"59","author":"Y Zhu","year":"1998","journal-title":"Biol Reprod"},{"issue":"1","key":"ref90","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0952-3278(92)90182-I","article-title":"Effects of beta-endorphin on spontaneous uterine contractions. Prostaglandins production and 45Ca2+ uptake in uterine strips from ovariectomized rats","volume":"47","author":"A Faletti","year":"1992","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"issue":"7481","key":"ref91","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/nature12886","article-title":"The complete genome sequence of a Neanderthal from the Altai Mountains","volume":"505","author":"K Prufer","year":"2014","journal-title":"Nature"},{"issue":"Suppl 3","key":"ref92","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1471-0528.2006.01120.x","article-title":"The preterm parturition syndrome","volume":"113","author":"R Romero","year":"2006","journal-title":"BJOG"}],"updated-by":[{"DOI":"10.1371\/journal.pone.0165328","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2016,10,19]],"date-time":"2016-10-19T00:00:00Z","timestamp":1476835200000}}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0160335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T02:42:42Z","timestamp":1589683362000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0160335"}},"subtitle":[],"editor":[{"given":"Zongli","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,8,4]]},"references-count":92,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2016,8,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0160335","relation":{"correction":[{"id-type":"doi","id":"10.1371\/journal.pone.0165328","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,4]]}}}