{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T11:57:29Z","timestamp":1773921449257,"version":"3.50.1"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["WO 1746\/1-2"],"award-info":[{"award-number":["WO 1746\/1-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0160430","type":"journal-article","created":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T20:11:29Z","timestamp":1472760689000},"page":"e0160430","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":14,"title":["Neuraminidase Inhibitors and Hospital Mortality in British Patients with H1N1 Influenza A: A Re-Analysis of Observational Data"],"prefix":"10.1371","volume":"11","author":[{"given":"Martin","family":"Wolkewitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Schumacher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2016,9,1]]},"reference":[{"issue":"10003","key":"ref1","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1016\/S0140-6736(15)00523-1","article-title":"Neuraminidase inhibitors for influenza: a call for better research","volume":"386","year":"2015","journal-title":"The Lancet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"g2545","DOI":"10.1136\/bmj.g2545","article-title":"Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments","volume":"348","author":"T Jefferson","year":"2014","journal-title":"BMJ"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"g2547","DOI":"10.1136\/bmj.g2547","article-title":"Zanamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments","volume":"348","author":"CJ Heneghan","year":"2014","journal-title":"BMJ"},{"issue":"9979","key":"ref4","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1016\/S0140-6736(14)62449-1","article-title":"Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials","volume":"385","author":"J Dobson","year":"2015","journal-title":"Lancet"},{"issue":"6","key":"ref5","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1093\/ije\/dyu219","article-title":"Cochrane column","volume":"43","author":"CS Wiysonge","year":"2014","journal-title":"Int J Epidemiol"},{"issue":"4","key":"ref6","doi-asserted-by":"crossref","first-page":"e60348","DOI":"10.1371\/journal.pone.0060348","article-title":"The value of neuraminidase inhibitors for the prevention and treatment of seasonal influenza: a systematic review of systematic reviews","volume":"8","author":"B Michiels","year":"2013","journal-title":"PLoS ONE"},{"issue":"8","key":"ref7","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1086\/656316","article-title":"Effectiveness of antiviral treatment in human influenza A(H5N1) infections: analysis of a Global Patient Registry","volume":"202","author":"W Adisasmito","year":"2010","journal-title":"J Infect Dis"},{"issue":"12","key":"ref8","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1086\/523584","article-title":"Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada","volume":"45","author":"A McGeer","year":"2007","journal-title":"Clin Infect Dis"},{"issue":"12","key":"ref9","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1086\/599031","article-title":"Clinical features of human influenza A (H5N1) infection in Vietnam: 2004\u20132006","volume":"48","author":"NT Liem","year":"2009","journal-title":"Clin Infect Dis"},{"issue":"5","key":"ref10","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S2213-2600(14)70041-4","article-title":"Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data","volume":"2","author":"SG Muthuri","year":"2014","journal-title":"Lancet Respir Med"},{"issue":"9","key":"ref11","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1093\/cid\/cis636","article-title":"Treatment with neuraminidase inhibitors for critically ill patients with influenza A (H1N1)pdm09","volume":"55","author":"JK Louie","year":"2012","journal-title":"Clin Infect Dis"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"g2371","DOI":"10.1136\/bmj.g2371","article-title":"Oseltamivir: the real world data","volume":"348","author":"N Freemantle","year":"2014","journal-title":"BMJ"},{"issue":"11","key":"ref13","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.jclinepi.2012.04.008","article-title":"Time-dependent study entries and exposures in cohort studies can easily be sources of different and avoidable types of bias","volume":"65","author":"M Wolkewitz","year":"2012","journal-title":"J Clin Epidemiol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"g5060","DOI":"10.1136\/bmj.g5060","article-title":"Interpreting and comparing risks in the presence of competing events","volume":"349","author":"M Wolkewitz","year":"2014","journal-title":"BMJ"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"f6409","DOI":"10.1136\/bmj.f6409","article-title":"Making inferences on treatment effects from real world data: propensity scores, confounding by indication, and other perils for the unwary in observational research","volume":"347","author":"N Freemantle","year":"2013","journal-title":"BMJ"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1093\/ije\/dyt111","article-title":"Hospital-acquired infections: appropriate statistical treatment is urgently needed","volume":"42","author":"M Schumacher","year":"2013","journal-title":"Int J Epidemiol"},{"issue":"7","key":"ref17","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1016\/S2213-2600(14)70126-2","article-title":"Statistical and methodological concerns about the beneficial effect of neuraminidase inhibitors on mortality","volume":"2","author":"M Jones","year":"2014","journal-title":"Lancet Respir Med"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"g3001","DOI":"10.1136\/bmj.g3001","article-title":"Mark Jones\u2019s reply to Myles and Leonardi-Bee\u2019s response to his critique of their paper reported in The BMJ","volume":"348","author":"M Jones","year":"2014","journal-title":"BMJ"},{"issue":"7","key":"ref19","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S2213-2600(14)70115-8","article-title":"Statistical and methodological concerns about the beneficial effect of neuraminidase inhibitors on mortality","volume":"2","author":"M Wolkewitz","year":"2014","journal-title":"Lancet Respir Med"},{"issue":"12","key":"ref20","doi-asserted-by":"crossref","first-page":"O979","DOI":"10.1111\/1469-0691.12708","article-title":"Should we recommend neuroaminidase inhibitors for influenza?","volume":"20","author":"L Leibovici","year":"2014","journal-title":"Clin Microbiol Infect"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"b5087","DOI":"10.1136\/bmj.b5087","article-title":"Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes","volume":"340","author":"LE L\u00e9vesque","year":"2010","journal-title":"BMJ"},{"issue":"3","key":"ref22","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1093\/ije\/dyu100","article-title":"Skin cancer as a marker of sun exposure: a case of serious immortality bias","volume":"43","author":"T Lange","year":"2014","journal-title":"Int J Epidemiol"},{"issue":"3","key":"ref23","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1093\/ije\/dyu105","article-title":"Avoiding blunders involving\u2019immortal time\u2019","volume":"43","author":"JA Hanley","year":"2014","journal-title":"Int J Epidemiol"},{"issue":"2","key":"ref24","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1093\/jac\/dkq424","article-title":"Mortality associated with in-hospital bacteraemia caused by Staphylococcus aureus: a multistate analysis with follow-up beyond hospital discharge","volume":"66","author":"M Wolkewitz","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jclinepi.2015.07.006","article-title":"Competing risk bias was common in Kaplan-Meier risk estimates published in prominent medical journals","volume":"69","author":"C van Walraven","year":"2016","journal-title":"J Clin Epidemiol"},{"issue":"8","key":"ref26","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1136\/thoraxjnl-2011-200266","article-title":"Predictors of clinical outcome in a national hospitalised cohort across both waves of the influenza A\/H1N1 pandemic 2009\u20132010 in the UK","volume":"67","author":"PR Myles","year":"2012","journal-title":"Thorax"},{"key":"ref27","article-title":"Competing Risks and Multistate Models with R","author":"J Beyersmann","year":"2011"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1086\/503375","article-title":"Use of multistate models to assess prolongation of intensive care unit stay due to nosocomial infection","volume":"27","author":"J Beyersmann","year":"2006","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref29","doi-asserted-by":"crossref","DOI":"10.1201\/b11311","article-title":"Dynamic Prediction in Clinical Survival Analysis","author":"HC van Houwelingen","year":"2011"},{"issue":"1","key":"ref30","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1002\/bimj.200900076","article-title":"Competing risks and time-dependent covariates","volume":"52","author":"G Cortese","year":"2010","journal-title":"Biom J"},{"issue":"446","key":"ref31","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","article-title":"A proportional hazards model for the subdistribution of a competing risk","volume":"94","author":"J Fine","year":"1999","journal-title":"J Am Stat Assoc"},{"issue":"16","key":"ref32","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.1002\/sim.5705","article-title":"The performance of different propensity score methods for estimating marginal hazard ratios","volume":"32","author":"PC Austin","year":"2013","journal-title":"Stat Med"},{"issue":"4","key":"ref33","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1093\/cid\/ciq144","article-title":"Risk factors for severe illness with 2009 pandemic influenza A (H1N1) virus infection in China","volume":"52","author":"H Yu","year":"2011","journal-title":"Clin Infect Dis"},{"issue":"7","key":"ref34","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.1016\/S2213-2600(14)70137-7","article-title":"Statistical and methodological concerns about the beneficial effect of neuraminidase inhibitors on mortality","volume":"2","author":"J Leonardi-Bee","year":"2014","journal-title":"Lancet Respir Med"},{"key":"ref35","article-title":"Hospitalization Fatality Risk of Influenza A(H1N1)pdm09: A Systematic Review and Meta-Analysis","author":"JY Wong","year":"2015","journal-title":"American Journal of Epidemiology"}],"updated-by":[{"DOI":"10.1371\/journal.pone.0175660","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2017,4,6]],"date-time":"2017-04-06T00:00:00Z","timestamp":1491436800000}}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0160430","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T04:38:06Z","timestamp":1718771886000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0160430"}},"subtitle":[],"editor":[{"given":"Hiroshi","family":"Nishiura","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,9,1]]},"references-count":35,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2016,9,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0160430","relation":{"correction":[{"id-type":"doi","id":"10.1371\/journal.pone.0175660","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,1]]}}}