{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T17:11:38Z","timestamp":1788369098457,"version":"build-2803163510"},"reference-count":22,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2016,9,9]],"date-time":"2016-09-09T00:00:00Z","timestamp":1473379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Medical Science and Technology Research Foundation of Guangdong province","award":["A2016136"],"award-info":[{"award-number":["A2016136"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81471654"],"award-info":[{"award-number":["81471654"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Natural Science Foundation of Guangdong Province, China","award":["2015A030313536"],"award-info":[{"award-number":["2015A030313536"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31400845"],"award-info":[{"award-number":["31400845"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0161935","type":"journal-article","created":{"date-parts":[[2016,9,9]],"date-time":"2016-09-09T14:17:57Z","timestamp":1473430677000},"page":"e0161935","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":38,"title":["Altered Resting-State Functional Connectivity of the Striatum in Parkinson's Disease after Levodopa Administration"],"prefix":"10.1371","volume":"11","author":[{"given":"Wanqun","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiwang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,9,9]]},"reference":[{"issue":"12","key":"ref1","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1002\/mds.21507","article-title":"Clinical diagnostic criteria for dementia associated with Parkinson's disease","volume":"22","author":"M Emre","year":"2007","journal-title":"Mov Disord"},{"issue":"Pt 12","key":"ref2","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1093\/brain\/aws281","article-title":"Resting state functional connectivity of the striatum in Parkinson's disease","volume":"135","author":"CD Hacker","year":"2012","journal-title":"Brain"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"e111600","DOI":"10.1371\/journal.pone.0111600","article-title":"Asymmetrical effect of levodopa on the neural activity of motor regions in PD","volume":"9","author":"K Martinu","year":"2014","journal-title":"PLoS One"},{"issue":"12","key":"ref4","doi-asserted-by":"crossref","first-page":"e0144986","DOI":"10.1371\/journal.pone.0144986","article-title":"Freezing of Gait in Parkinson's Disease: An Overload Problem?","volume":"10","author":"EN Beck","year":"2015","journal-title":"PLoS One"},{"issue":"10","key":"ref5","doi-asserted-by":"crossref","first-page":"e110547","DOI":"10.1371\/journal.pone.0110547","article-title":"Neural substrates of cognitive subtypes in Parkinson's disease: a 3-year longitudinal study","volume":"9","author":"Y Shoji","year":"2014","journal-title":"PLoS One"},{"issue":"12","key":"ref6","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1093\/cercor\/bhn041","article-title":"Functional connectivity of human striatum: a resting state FMRI study","volume":"18","author":"A Di Martino","year":"2008","journal-title":"Cereb Cortex"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1093\/cercor\/bhp178","article-title":"Spatial remapping of cortico-striatal connectivity in Parkinson's disease","volume":"20","author":"RC Helmich","year":"2010","journal-title":"Cereb Cortex"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.neulet.2013.05.080","article-title":"Changes in spontaneous brain activity in early Parkinson's disease","volume":"549","author":"H Yang","year":"2013","journal-title":"Neuroscience letters"},{"issue":"Pt 5","key":"ref9","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1093\/brain\/awr075","article-title":"The effect of dopamine therapy on ventral and dorsal striatum-mediated cognition in Parkinson's disease: support from functional MRI","volume":"134","author":"PA MacDonald","year":"2011","journal-title":"Brain"},{"issue":"4","key":"ref10","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s00702-011-0723-5","article-title":"The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent","volume":"119","author":"L Krajcovicova","year":"2011","journal-title":"J Neural Transm"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3389\/fnsys.2010.00143","article-title":"Altered resting state cortico-striatal connectivity in mild to moderate stage Parkinson's disease","volume":"4","author":"Y Kwak","year":"2010","journal-title":"Front Syst Neurosci"},{"issue":"5","key":"ref12","first-page":"534","article-title":"The Unified Parkinson's Disease Rating Scale","volume":"156","author":"AM Bonnet","year":"2000","journal-title":"Revue neurologique"},{"issue":"3","key":"ref13","first-page":"189","article-title":""Mini-mental state". A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"MF Folstein","year":"1975","journal-title":"Journal of psychiatric research"},{"issue":"4","key":"ref14","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","article-title":"The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment","volume":"53","author":"ZS Nasreddine","year":"2005","journal-title":"Journal of the American Geriatrics Society"},{"issue":"5","key":"ref15","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1212\/WNL.17.5.427","article-title":"Parkinsonism: onset, progression and mortality","volume":"17","author":"MM Hoehn","year":"1967","journal-title":"Neurology"},{"issue":"5","key":"ref16","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/ana.410070516","article-title":"Pathological verification of ischemic score in differentiation of dementias","volume":"7","author":"WG Rosen","year":"1980","journal-title":"Annals of neurology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1192\/bjp.140.6.566","article-title":"A new clinical scale for the staging of dementia","volume":"140","author":"CP Hughes","year":"1982","journal-title":"The British journal of psychiatry: the journal of mental science"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1002\/hbm.23056","article-title":"Resting-state functional connectivity of the striatum in early-stage Parkinson's disease: Cognitive decline and motor symptomatology","volume":"37","author":"P Manza","year":"2016","journal-title":"Human brain mapping"},{"issue":"1","key":"ref19","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.neuroimage.2010.11.074","article-title":"Effective connectivity of brain networks during self-initiated movement in Parkinson's disease","volume":"55","author":"T Wu","year":"2011","journal-title":"Neuroimage"},{"issue":"1","key":"ref20","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s00441-004-0956-9","article-title":"Stages in the development of Parkinson's disease-related pathology","volume":"318","author":"H Braak","year":"2004","journal-title":"Cell Tissue Res"},{"issue":"1","key":"ref21","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.neulet.2009.05.046","article-title":"Changes of functional connectivity of the motor network in the resting state in Parkinson's disease","volume":"460","author":"T Wu","year":"2009","journal-title":"Neuroscience letters"},{"issue":"9","key":"ref22","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1212\/WNL.0b013e31822c6224","article-title":"Network correlates of the cognitive response to levodopa in Parkinson disease","volume":"77","author":"PJ Mattis","year":"2011","journal-title":"Neurology"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0161935","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T23:18:15Z","timestamp":1540336695000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0161935"}},"subtitle":[],"editor":[{"given":"Xi-Nian","family":"Zuo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,9,9]]},"references-count":22,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2016,9,9]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0161935","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,9]]}}}