{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:10:36Z","timestamp":1787238636810,"version":"build-2736575974"},"reference-count":56,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2016,8,31]],"date-time":"2016-08-31T00:00:00Z","timestamp":1472601600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0162061","type":"journal-article","created":{"date-parts":[[2016,8,31]],"date-time":"2016-08-31T14:16:01Z","timestamp":1472652961000},"page":"e0162061","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":76,"title":["The Occupational Risk of Influenza A (H1N1) Infection among Healthcare Personnel during the 2009 Pandemic: A Systematic Review and Meta-Analysis of Observational Studies"],"prefix":"10.1371","volume":"11","author":[{"given":"Janna","family":"Lietz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Westermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Nienhaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Schablon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,8,31]]},"reference":[{"key":"ref1","first-page":"467","article-title":"Outbreak of swine-origin influenza A (H1N1) virus infection\u2014Mexico, March-April 2009","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"ref2","unstructured":"World Health Organization (WHO). World now at the start of 2009 influenza pandemic. Statement to the press by WHO Director-General Dr. Margaret Chan; 2009. Available: http:\/\/www.who.int\/mediacentre\/news\/statements\/2009\/h1n1_pandemic_phase6_20090611\/en\/<\/ext-link>."},{"key":"ref3","unstructured":"World Health Organization (WHO). H1N1 in post-pandemic period. Director-General's opening statement at virtual press conference 10 August 2010; 2010. Available: http:\/\/www.who.int\/mediacentre\/news\/statements\/2010\/h1n1_vpc_20100810\/en\/<\/ext-link>."},{"key":"ref4","unstructured":"World Health Organization (WHO). Pandemic (H1N1) 2009\u2014update 112; 2010a. Available: http:\/\/www.who.int\/csr\/don\/2010_08_06\/en\/<\/ext-link>."},{"key":"ref5","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.jinf.2011.04.009","article-title":"Risk factors for pandemic H1N1 2009 infection in healthcare personnel of four general hospitals","volume":"63","author":"SH Choi","year":"2011","journal-title":"J Infect"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.ajic.2012.08.012","article-title":"Pandemic 2009 H1N1 influenza among health care workers","volume":"41","author":"R Lobo","year":"2013","journal-title":"Am J Infect Control"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.3201\/eid1509.081475","article-title":"Nurses' contacts and potential for infectious disease transmission","volume":"15","author":"H Bernard","year":"2009","journal-title":"Emerg Infect Dis"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.3201\/eid1107.041038","article-title":"Occupational deaths among healthcare workers","volume":"11","author":"KA Sepkowitz","year":"2005","journal-title":"Emerg Infect Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1001\/jama.283.15.2008","article-title":"Meta-analysis of observational studies in epidemiology: a proposal for reporting","volume":"283","author":"DF Stroup","year":"2000","journal-title":"JAMA"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"D Moher","year":"2015","journal-title":"Syst Rev"},{"key":"ref11","unstructured":"Centre for Reviews and Dissemination, University of York. Systematic Reviews: CRD's guidance for undertaking reviews in health care. 3rd ed. York: York Publ. Services; 2009."},{"key":"ref12","unstructured":"Robert Koch-Institut (RKI). Influenza (Saisonale Influenza, Influenza A(H1N1) 2009, Avi\u00e4re Influenza). RKI-Ratgeber f\u00fcr \u00c4rzte; 20.12.2013. Available: https:\/\/www.rki.de\/DE\/Content\/Infekt\/EpidBull\/Merkblaetter\/Ratgeber_Influenza.html#doc2382022bodyText2<\/ext-link>."},{"key":"ref13","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1136\/jech.52.6.377","article-title":"The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions","volume":"52","author":"SH Downs","year":"1998","journal-title":"J Epidemiol Community Health"},{"key":"ref14","first-page":"170","article-title":"Critical appraisal of the health research literature: prevalence or incidence of a health problem","volume":"19","author":"PL Loney","year":"1998","journal-title":"Chronic Dis Can"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1093\/ptj\/79.4.384","article-title":"The prevalence of low back pain in adults: a methodological review of the literature","volume":"79","author":"PL Loney","year":"1999","journal-title":"Phys Ther"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1186\/1471-2334-10-255","article-title":"Seroepidemiology of pandemic influenza A (H1N1) 2009 virus infections in Pune, India","volume":"10","author":"BV Tandale","year":"2010","journal-title":"BMC Infect Dis"},{"key":"ref17","unstructured":"Higgins JP, Green S. Cochrane Handbook for Systematic Reviews of Interventions; March 2011. Available: http:\/\/handbook.cochrane.org\/<\/ext-link>."},{"key":"ref18","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"M Egger","year":"1997","journal-title":"BMJ"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1086\/662709","article-title":"Transmission of 2009 pandemic influenza A (H1N1) virus among healthcare personnel-Southern California, 2009","volume":"32","author":"JL Jaeger","year":"2011","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00420-011-0652-5","article-title":"Low attack rate of novel influenza A (H1N1) virus infection among healthcare workers: a prospective study in a setting with an elaborated containment plan","volume":"85","author":"P Smit","year":"2012","journal-title":"Int Arch Occup Environ Health"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1007\/s00420-011-0714-8","article-title":"High effectiveness of pandemic influenza A (H1N1) vaccination in healthcare workers from a Portuguese hospital","volume":"85","author":"JT Costa","year":"2012","journal-title":"Int Arch Occup Environ Health"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1086\/656241","article-title":"Epidemiology of H1N1 (2009) influenza among healthcare workers in a tertiary care center in Saudi Arabia: a 6-month surveillance study","volume":"31","author":"HH Balkhy","year":"2010","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1086\/656480","article-title":"Effectiveness of public health measures in mitigating pandemic influenza spread: a prospective sero-epidemiological cohort study","volume":"202","author":"VJ Lee","year":"2010","journal-title":"J Infect Dis"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/1471-2334-12-89","article-title":"Longitudinal seroepidemiologic study of the 2009 pandemic influenza A (H1N1) infection among health care workers in a children's hospital","volume":"12","author":"T-Y Yen","year":"2012","journal-title":"BMC Infect Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1086\/663208","article-title":"Pandemic 2009 influenza A (H1N1) virus among Japanese healthcare workers: seroprevalence and risk factors","volume":"33","author":"Y Nukui","year":"2012","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref26","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/407505","article-title":"Prevalence of influenza A (H1N1) seropositivity in unvaccinated healthcare workers in Scotland at the height of the global pandemic","volume":"2011","author":"K Smith","year":"2011","journal-title":"J Environ Public Health"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1086\/671271","article-title":"Impact of the 2009 influenza A (H1N1) pandemic on healthcare workers at a tertiary care center in New York City","volume":"34","author":"N Bhadelia","year":"2013","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1097\/PEC.0b013e31822c125e","article-title":"H1N1 hemagglutinin-inhibition seroprevalence in emergency department health care workers after the first wave of the 2009 influenza pandemic","volume":"27","author":"S Kumar","year":"2011","journal-title":"Pediatr Emerg Care"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"e13211","DOI":"10.1371\/journal.pone.0013211","article-title":"Risk factors and immunity in a nationally representative population following the 2009 influenza A(H1N1) pandemic","volume":"5","author":"D Bandaranayake","year":"2010","journal-title":"PLoS ONE"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1001\/jama.2010.404","article-title":"2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore","volume":"303","author":"M I C Chen","year":"2010","journal-title":"JAMA"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jinf.2011.05.001","article-title":"Seroprevalence of antibodies to pandemic (H1N1) 2009 influenza virus among health care workers in two general hospitals after first outbreak in Kobe, Japan","volume":"63","author":"T Toyokawa","year":"2011","journal-title":"J Infect"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.jhin.2011.02.017","article-title":"Seroprevalence of antibody to pandemic influenza A (H1N1) 2009 among healthcare workers after the first wave in Hong Kong","volume":"78","author":"Y Zhou","year":"2011","journal-title":"J Hosp Infect"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.arcmed.2015.03.001","article-title":"Seroprevalence of pandemic A(H1N1) pmd09 irus antibodies in Mexican health care workers before and after vaccination","volume":"46","author":"G Aguilar-Madrid","year":"2015","journal-title":"Arch Med Res"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3201\/eid1901.111640","article-title":"Seropositivity for influenza A(H1N1)pdm09 virus among frontline health care personnel","volume":"19","author":"K Alagappan","year":"2013","journal-title":"Emerg Infect Dis"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"e416","DOI":"10.3399\/bjgp13X668212","article-title":"Pandemic influenza A(H1N1)pdm09: risk of infection in primary healthcare workers","volume":"63","author":"B Hudson","year":"2013","journal-title":"Br J Gen Pract"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"606","DOI":"10.3201\/eid1904.111812","article-title":"Risk factors for influenza among health care workers during 2009 pandemic, Toronto, Ontario, Canada","volume":"19","author":"SP Kuster","year":"2013","journal-title":"Emerg Infect Dis"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.3201\/eid\/1706.101030","article-title":"Pandemic (H1N1) 2009 risk for frontline health care workers","volume":"17","author":"C Marshall","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.eimc.2011.11.019","article-title":"Seroprevalence of antibodies to the influenza A (H1N1) virus among healthcare workers prior to the 2009 pandemic peak","volume":"30","author":"J Olalla","year":"2012","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1007\/s10096-011-1213-2","article-title":"H1N1 influenza infection in Korean healthcare personnel","volume":"30","author":"JS Yeom","year":"2011","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref40","unstructured":"Bandaranayake D, Huang QS, Bissielo A, Wood T. Seroprevalence of the 2009 influenza A (H1N1) pandemic in New Zealand; May 2010a."},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.3201\/eid1610.100516","article-title":"Risk factors for pandemic (H1N1) 2009 virus seroconversion among hospital staff, Singapore","volume":"16","author":"M I C Chen","year":"2010","journal-title":"Emerg Infect Dis"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S1726-4901(10)70003-4","article-title":"Seroprevalence of antibodies to pandemic (H1N1) 2009 influenza virus among hospital staff in a medical center in Taiwan","volume":"73","author":"Y-J Chan","year":"2010","journal-title":"J Chin Med Assoc"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1093\/cid\/cir375","article-title":"Clinical and nonclinical health care workers faced a similar risk of acquiring 2009 pandemic H1N1 infection","volume":"53","author":"WH Seto","year":"2011","journal-title":"Clin Infect Dis"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1017\/S193578930000241X","article-title":"Which health care workers were most affected during the spring 2009 H1N1 pandemic","volume":"4","author":"CD Santos","year":"2010","journal-title":"Disaster Med Public Health Prep"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1745-6673-9-9","article-title":"Tuberculosis in healthcare workers\u2014a narrative review from a German perspective","volume":"9","author":"A Nienhaus","year":"2014","journal-title":"J Occup Med Toxicol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1136\/oemed-2011-100068","article-title":"Infectious disease risks associated with occupational exposure: a systematic review of the literature","volume":"69","author":"JA Haagsma","year":"2012","journal-title":"Occup Environ Med"},{"key":"ref47","first-page":"710","article-title":"Emerging occupational lung infections","volume":"11","author":"PL Ho","year":"2007","journal-title":"Int J Tuberc Lung Dis"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1750-2659.2011.00326.x","article-title":"Seroprevalence of pandemic (H1N1) 2009 influenza and effectiveness of 2010\/2011 influenza vaccine during 2010\/2011 season in Beijing, China","volume":"6","author":"P Yang","year":"2012","journal-title":"Influenza Other Respir Viruses"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"e17919","DOI":"10.1371\/journal.pone.0017919","article-title":"The seroprevalence of pandemic influenza H1N1 (2009) virus in China","volume":"6","author":"C Xu","year":"2011","journal-title":"PLoS ONE"},{"key":"ref50","first-page":"67","article-title":"Determination of antibody response to the human pandemic influenza H1N1 2009 among patients with influenza-like illness and high risk groups","volume":"28","author":"J Makkoch","year":"2010","journal-title":"Asian Pac J Allergy Immunol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1086\/660097","article-title":"Investigation of an outbreak of 2009 pandemic influenza A virus (H1N1) infections among healthcare personnel in a Chicago hospital","volume":"32","author":"SS Magill","year":"2011","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jhin.2009.11.001","article-title":"H1N1 2009 influenza among healthcare workers in a tertiary care hospital in Thailand","volume":"74","author":"S Kiertiburanakul","year":"2010","journal-title":"J Hosp Infect"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jhin.2009.09.009","article-title":"Prevention of nosocomial transmission of swine-origin pandemic influenza virus A\/H1N1 by infection control bundle","volume":"74","author":"V C C Cheng","year":"2010","journal-title":"J Hosp Infect"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1086\/658911","article-title":"Factors associated with unprotected exposure to 2009 H1N1 influenza A among healthcare workers during the first wave of the pandemic","volume":"32","author":"DB Banach","year":"2011","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1086\/654807","article-title":"Factors associated with health care-associated 2009 influenza a (H1N1) virus infection among Thai health care workers","volume":"51","author":"A Apisarnthanarak","year":"2010","journal-title":"Clin Infect Dis"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.jclinepi.2011.03.017","article-title":"GRADE guidelines: 7. Rating the quality of evidence\u2014inconsistency","volume":"64","author":"GH Guyatt","year":"2011","journal-title":"J Clin Epidemiol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0162061","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T09:49:01Z","timestamp":1657187341000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0162061"}},"subtitle":[],"editor":[{"given":"Benjamin J.","family":"Cowling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,8,31]]},"references-count":56,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2016,8,31]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0162061","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,31]]}}}