{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T02:34:16Z","timestamp":1773628456654,"version":"3.50.1"},"reference-count":63,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T00:00:00Z","timestamp":1476748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008370","name":"National Pork Board","doi-asserted-by":"publisher","award":["556678"],"award-info":[{"award-number":["556678"]}],"id":[{"id":"10.13039\/100008370","id-type":"DOI","asserted-by":"publisher"}]},{"name":"College of Veterinary Medicine, NCSU"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0164621","type":"journal-article","created":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T17:31:53Z","timestamp":1476811913000},"page":"e0164621","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":42,"title":["Assessing the Impact of Manure Application in Commercial Swine Farms on the Transmission of Antimicrobial Resistant Salmonella in the Environment"],"prefix":"10.1371","volume":"11","author":[{"given":"Suchawan","family":"Pornsukarom","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siddhartha","family":"Thakur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2016,10,18]]},"reference":[{"key":"ref1","article-title":"Literature review of contaminants in livestock and poultry manure and implications for water quality","year":"2013"},{"key":"ref2","unstructured":"USDA. FY-2005 Annual Report Manure and Byproduct Utilization, National Program 206. 2008. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.ars.usda.gov\/research\/programs\/programs.htm?np_code=206&docid=13337\" xlink:type=\"simple\">http:\/\/www.ars.usda.gov\/research\/programs\/programs.htm?np_code=206&amp;docid=13337<\/ext-link>"},{"issue":"9","key":"ref3","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.4315\/0362-028X.JFP-14-111","article-title":"Thermal and Nonthermal Factors Affecting Survival of <italic>Salmonella<\/italic> and <italic>Listeria monocytogenes<\/italic> in Animal Manure\u2013Based Compost Mixtures","volume":"77","author":"MC Erickson","year":"2014","journal-title":"Journal of Food Protection"},{"issue":"11","key":"ref4","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1016\/j.wasman.2014.07.021","article-title":"Pathogen reduction in minimally managed composting of bovine manure","volume":"34","author":"P Millner","year":"2014","journal-title":"Waste Management"},{"key":"ref5","first-page":"210","article-title":"Discharge of swine wastes risks water quality and food safety: Antibiotics and antibiotic resistance genes from swine sources to the receiving environments","volume":"92","author":"LY He","year":"2016","journal-title":"Environment international"},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/ejss.12216","article-title":"Soil, food security and human health: a review","volume":"66","author":"MA Oliver","year":"2015","journal-title":"European Journal of Soil Science"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"882","DOI":"10.2134\/jeq2009.0289","article-title":"Source-pathway separation of multiple contaminants during a rainfall-runoff event in an artificially drained agricultural watershed","volume":"39","author":"MD Tomer","year":"2010","journal-title":"J Environ Qual"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.2134\/jeq2008.0128","article-title":"Fate and Transport of Antibiotic Residues and Antibiotic Resistance Genes following Land Application of Manure Waste","volume":"38","author":"JC Chee-Sanford","year":"2009","journal-title":"J Environ Qual"},{"issue":"6","key":"ref9","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.2134\/jeq2008.0471","article-title":"Antibiotic resistant bacterial profiles of anaerobic swine lagoon effluent","volume":"38","author":"JP Brooks","year":"2009","journal-title":"J Environ Qual"},{"issue":"12","key":"ref10","doi-asserted-by":"crossref","first-page":"7813","DOI":"10.1128\/AEM.01087-06","article-title":"Antimicrobial use and resistance in swine manure treatment systems","volume":"72","author":"A Jindal","year":"2006","journal-title":"Appl Environ Microbiol"},{"issue":"11","key":"ref11","doi-asserted-by":"crossref","first-page":"6507","DOI":"10.1128\/AEM.69.11.6507-6514.2003","article-title":"Evaluation of F+ RNA and DNA coliphages as source-specific indicators of fecal contamination in surface waters","volume":"69","author":"D Cole","year":"2003","journal-title":"Appl Environ Microbiol"},{"issue":"3","key":"ref12","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1128\/AEM.00615-09","article-title":"Transport and distribution of <italic>Salmonella enterica<\/italic> Serovar Typhimurium in loamy and sandy soil monoliths with applied liquid manure","volume":"76","author":"TB Bech","year":"2010","journal-title":"Appl Environ Microbiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"5777","DOI":"10.1128\/AEM.00791-06","article-title":"Survival of <italic>Salmonella enterica<\/italic> serovar Newport in manure and manure-amended soils","volume":"72","author":"YW You","year":"2006","journal-title":"Applied and Environmental Microbiology"},{"issue":"9","key":"ref14","doi-asserted-by":"crossref","first-page":"5111","DOI":"10.1128\/AEM.70.9.5111-5118.2004","article-title":"Effect of length of time before incorporation on survival of pathogenic bacteria present in livestock wastes applied to agricultural soil","volume":"70","author":"ML Hutchinson","year":"2004","journal-title":"Appl Environ Microbiol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1111\/j.1365-2672.2011.04956.x","article-title":"Survival of <italic>Escherichia coli<\/italic> O157:H7 and <italic>Salmonella enterica<\/italic> Serovar Typhimurium in manure and manure-amended soil under tropical climatic conditions in Sub-Saharan Africa","volume":"110","author":"D Ongeng","year":"2011","journal-title":"J Appl Microbiol"},{"issue":"12","key":"ref16","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1002\/jsfa.6593","article-title":"Fate and survival of <italic>Salmonella<\/italic> Typhimurium and <italic>Escherichia coli<\/italic> O157: H7 in repacked soil lysimeters after application of cattle slurry and human urine","volume":"94","author":"KA Nyberg","year":"2014","journal-title":"Journal of the science of food and agriculture"},{"issue":"3","key":"ref17","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.livsci.2007.09.001","article-title":"Recycling of livestock manure in a whole-farm perspective","volume":"112","author":"SO Petersena","year":"2007","journal-title":"Livestock Science"},{"key":"ref18","article-title":"Census of Agriculture","year":"2007"},{"key":"ref19","first-page":"78","article-title":"Swine manure management","volume":"44","author":"JL Hatfield","year":"1998","journal-title":"Agricultural uses of municipal, animal, and industrial byproducts"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.agee.2015.11.020","article-title":"Level and distribution of odorous compounds in pig exhaust air from combined room and pit ventilation","volume":"218","author":"K Van Huffel","year":"2016","journal-title":"Agriculture, Ecosystems & Environment"},{"key":"ref21","unstructured":"Barker JC, Driggers LB. Pit Recharge System for Managing Swine Underfloor Manure Pits. In: Agricultural Waste Utilization and Management, Proceedings of the Fifth International Symposium on Agricultural Wastes. 1985; 575\u2013581."},{"key":"ref22","unstructured":"Reid JH, inventor. Anaerobic lagoon or tank design for effluent carbon to nitrogen ratio control. United States patent US 9,005,442. 2015."},{"key":"ref23","first-page":"49085","article-title":"Design of Anaerobic Lagoons for Animal Waste Management","year":"1998"},{"key":"ref24","article-title":"Methods and Timing for Manure Application","year":"1995"},{"key":"ref25","first-page":"295","article-title":"Animal Manure Recycling: Treatment and Management","author":"LS Jensen","year":"2013"},{"issue":"9","key":"ref26","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1093\/jac\/dkr228","article-title":"Leakage of emerging clinically relevant multidrug-resistant <italic>Salmonella<\/italic> clones from pig farms","volume":"66","author":"P Antunes","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.prevetmed.2005.02.007","article-title":"Survival of <italic>Escherichia coli<\/italic> and <italic>Salmonella<\/italic> Typhimurium in slurry applied to clay soil on a Danish swine farm","volume":"69","author":"J Boes","journal-title":"Prev Vet Med. 2005"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.soilbio.2015.07.027","article-title":"Effects of long-term manure applications on the occurrence of antibiotics and antibiotic resistance genes (ARGs) in paddy soils: Evidence from four field experiments in south of China","volume":"90","author":"X Tang","year":"2015","journal-title":"Soil Biology and Biochemistry"},{"issue":"6","key":"ref29","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.2134\/jeq2007.0304","article-title":"Examination of <italic>Salmonella<\/italic> and <italic>Escherichia coli<\/italic> translocation from hog manure to forage, soil, and cattle grazed on the hog manure-treated pasture","volume":"37","author":"R Holley","year":"2008","journal-title":"J Environ Qual"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.mib.2014.05.017","article-title":"Impact of antibiotic use in the swine industry","volume":"19","author":"MD Barton","year":"2014","journal-title":"Current opinion in microbiology"},{"issue":"1","key":"ref31","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1177\/003335491212700103","article-title":"A Review of Antibiotic Use in Food Animals: Perspective, Policy, and Potential","volume":"127","author":"TF Landers","year":"1974","journal-title":"Public Health Reports"},{"key":"ref32","first-page":"1","article-title":"Manure Application Rate Guide","volume":"1","year":"2012"},{"issue":"1","key":"ref33","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.agee.2010.01.001","article-title":"The impacts of manure application methods on emissions of ammonia, nitrous oxide and on crop response\u2014a review","volume":"137","author":"J Webb","year":"2010","journal-title":"Agriculture, Ecosystems & Environment"},{"issue":"17","key":"ref34","doi-asserted-by":"crossref","first-page":"5167","DOI":"10.1128\/AEM.01419-13","article-title":"Longitudinal Study of Distributions of Similar Antimicrobial-Resistant <italic>Salmonella<\/italic> Serovars in Pigs and Their Environment in Two Distinct Swine Production Systems","volume":"79","author":"S Keelara","year":"2013","journal-title":"Appl. Environ. Microbiol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.vetmic.2007.05.025","article-title":"Occurrence of multidrug resistant Salmonella in antimicrobial-free (ABF) swine production systems","volume":"125","author":"S Thakur","year":"2007","journal-title":"Vet. Microbiol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"743","DOI":"10.4315\/0362-028X-69.4.743","article-title":"Comparison of prevalence, antimicrobial resistance, and occurrence of multidrug-resistant <italic>Salmonella<\/italic> in antimicrobial-free and conventional pig production","volume":"69","author":"W Gebreyes","year":"2006","journal-title":"J. Food. Prot"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0378-1135(02)00028-7","article-title":"Detection and identification of <italic>salmonella<\/italic> from poultry-related samples by PCR","volume":"87","author":"S Oliveira","year":"2002","journal-title":"Vet. Microbiol"},{"key":"ref38","article-title":"CLSI document M02-A10","year":"2013"},{"key":"ref39","article-title":"Executive report. National Antimicrobial Resistance Monitoring System","year":"2009"},{"key":"ref40","article-title":"Standardized Molecular Subtyping of Foodborne Bacterial Pathogens by Pulsed-Field Gel Electrophoresis","year":"2004"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"374","DOI":"10.2166\/wh.2009.076","article-title":"The occurrence and sources of <italic>Campylobacter<\/italic> spp., <italic>Salmonella enterica<\/italic> and <italic>Escherichia coli<\/italic> O157:H7 in the Salmon River, British Columbia, Canada","volume":"8","author":"CC Jokinen","year":"2010","journal-title":"Journal of Water and Health"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1128\/AEM.01648-08","article-title":"Distribution, Diversity, and Seasonality of Waterborne Salmonellae in a Rural Watershed","volume":"75","author":"BJ Haley","year":"2009","journal-title":"Applied and Environmental Microbiology"},{"issue":"2","key":"ref43","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.foodres.2011.07.026","article-title":"Soil survival of <italic>Salmonella<\/italic> and transfer to freshwater and fresh produce","volume":"45","author":"CS Jacobsen","year":"2012","journal-title":"Food Research International"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.2134\/jeq2005.0449","article-title":"<italic>Salmonella<\/italic> survival in manure-treated soils during simulated seasonal temperature exposure","volume":"35","author":"RA Holley","year":"2006","journal-title":"Journal of Environmental Quality"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1128\/AEM.70.4.2497-2502.2004","article-title":"Fate of <italic>Salmonella enterica<\/italic> serovar Typhimurium on carrots and radishes grown in fields treated with contaminated manure composts or irrigation water","volume":"70","author":"M Islam","year":"2004","journal-title":"Applied and Environmental Microbiology"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.apsoil.2015.01.011","article-title":"Enteropathogen survival in soil from different land-uses is predominantly regulated by microbial community composition","volume":"89","author":"EL Moynihan","year":"2015","journal-title":"Applied Soil Ecology"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1128\/AEM.34.3.270-273.1977","article-title":"Increased recovery of Salmonellae from environmental samples enriched with buffered peptone water","volume":"34","author":"BM Thomason","year":"1977","journal-title":"Appl. Environ. Microbiol"},{"key":"ref48","doi-asserted-by":"crossref","unstructured":"Abley M, Fedorka-Cray PJ, Gebreyes W, McKean J, Davies P, Thakur S, et al. Prevalence and Antimicrobial Resistance of Salmonella, E. coli, and Campylobacter in Pigs from Swine Producing States in the United States. Safepork 2013 Procedings. 2013; 76\u201378.","DOI":"10.31274\/safepork-180809-215"},{"key":"ref49","unstructured":"Centers for Disease Control and Prevention (CDC). National Salmonella Surveillance Annual Report\u2014Appendices, 2011. Atlanta, Georgia: US Department of Health and Human Services, CDC; 2013."},{"key":"ref50","article-title":"How <italic>Salmonella<\/italic> Rissen Came to America","author":"D Flynn","year":"2010"},{"key":"ref51","article-title":"Outbreak of <italic>Salmonella<\/italic> Rissen associated with Ground White Pepper: The Epi Investigation","author":"J Higa","year":"2011"},{"issue":"2","key":"ref52","doi-asserted-by":"crossref","first-page":"e0116581","DOI":"10.1371\/journal.pone.0116581","article-title":"Comparative phenotypic and genotypic characterization of Salmonella spp. in pig farms and slaughterhouses in two provinces in northern Thailand","volume":"10","author":"P Tadee","year":"2015","journal-title":"PloS one"},{"issue":"2","key":"ref53","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/zph.12144","article-title":"Comparative Phenotypic and Genotypic Analyses of <italic>Salmonella<\/italic> Rissen that Originated from Food Animals in Thailand and United States","volume":"62","author":"S Pornsukarom","year":"2015","journal-title":"Zoonoses and public health"},{"issue":"3","key":"ref54","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.jgar.2013.05.001","article-title":"<italic>Salmonella<\/italic> prevalence in meat at retail markets in Pakse, Champasak Province, Laos, and antimicrobial susceptibility of isolates","volume":"1","author":"S Boonmar","year":"2013","journal-title":"Journal of Global Antimicrobial Resistance"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.prevetmed.2008.06.022","article-title":"A cross-sectional study of <italic>Salmonella<\/italic> in pre-slaughter pigs in a production compartment of northern Thailand","volume":"88","author":"S Dorn-in","year":"2009","journal-title":"Prev. Vet. Med"},{"issue":"1","key":"ref56","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.vetmic.2015.05.005","article-title":"Prevalence and characterization of Salmonella in pigs from conventional and organic farms and first report of S. serovar 1, 4,[5], 12: i:-from Korea","volume":"178","author":"MD Tamang","year":"2015","journal-title":"Veterinary microbiology"},{"issue":"3","key":"ref57","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.mib.2011.04.009","article-title":"Antibiotic resistance gene spread due to manure application on agricultural fields","volume":"14","author":"H Heuer","year":"2011","journal-title":"Current opinion in microbiology"},{"key":"ref58","article-title":"Swine 2006 part III: reference of swine health, productivity, and general management in the United States, 2006","year":"2008"},{"issue":"3","key":"ref59","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.ijfoodmicro.2012.11.001","article-title":"A study of <italic>Salmonella<\/italic> in pigs from birth to carcass: Serotypes, genotypes, antibiotic resistance and virulence profiles","volume":"160","author":"DJ Bolton","year":"2013","journal-title":"International journal of food microbiology"},{"issue":"4","key":"ref60","doi-asserted-by":"crossref","first-page":"e95772","DOI":"10.1371\/journal.pone.0095772","article-title":"An association of genotypes and antimicrobial resistance patterns among Salmonella Isolates from pigs and humans in Taiwan","volume":"9","author":"HC Kuo","year":"2014","journal-title":"PloS one"},{"issue":"6","key":"ref61","doi-asserted-by":"crossref","first-page":"2859","DOI":"10.1128\/AEM.67.6.2859-2862.2001","article-title":"Persistence of a <italic>Salmonella enterica<\/italic> Serovar Typhimurium DT12 clone in a piggery and in agricultural soil amended with <italic>Salmonella<\/italic>-contaminated slurry","volume":"67","author":"SB Baloda","year":"2001","journal-title":"Appl Environ Microbiol"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.envpol.2016.03.038","article-title":"Distribution of antibiotic resistance genes (ARGs) in anaerobic digestion and land application of swine wastewater","volume":"213","author":"Q Sui","year":"2016","journal-title":"Environmental Pollution"},{"issue":"21","key":"ref63","doi-asserted-by":"crossref","first-page":"12081","DOI":"10.1021\/es4026358","article-title":"Fate and Transport of Antimicrobials and Antimicrobial Resistance Genes in Soil and Runoff Following Land Application of Swine Manure Slurry","volume":"47","author":"SR Joy","year":"2013","journal-title":"Environ. Sci. Technol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0164621","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T19:07:43Z","timestamp":1601147263000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0164621"}},"subtitle":[],"editor":[{"given":"Andrew C","family":"Singer","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,10,18]]},"references-count":63,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2016,10,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0164621","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,18]]}}}