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Global Report: UNAIDS report on the global AIDS epidemic. UNAIDS 2013. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.unaids.org\/en\/media\/unaids\/contentassets\/documents\/epidemiology\/2013\/gr2013\/unaids_global_report_2013_en.pdf\" xlink:type=\"simple\">http:\/\/www.unaids.org\/en\/media\/unaids\/contentassets\/documents\/epidemiology\/2013\/gr2013\/unaids_global_report_2013_en.pdf<\/ext-link>. Accessed 7 July 2014."},{"year":"2013","key":"ref2","article-title":"Boletim epidemiol\u00f3gico\u2014AIDS e DST"},{"year":"2013","key":"ref3","article-title":"Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1007\/s11524-011-9552-y","article-title":"An epidemic in evolution: the need for new models of HIV care in the chronic disease era","volume":"88","author":"C Chu","year":"2011","journal-title":"J Urban Health"},{"year":"2013","key":"ref5","article-title":"Protocolo cl\u00ednico e diretrizes terap\u00eauticas para manejo da infec\u00e7\u00e3o pelo HIV em adultos"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.5414\/CP201818","article-title":"Evaluation of adverse events associated with antiretroviral therapy and the relationship to treatment adherence","volume":"51","author":"L Lenzi","year":"2013","journal-title":"Int J Clin Pharmacol Ther"},{"key":"ref7","first-page":"1443","article-title":"Common adverse effects of antiretroviral therapy for HIV disease","volume":"83","author":"CE Reust","year":"2011","journal-title":"Am Fam Physician"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jana.2006.01.005","article-title":"Symptom management of HIV-related diarrhea by using normal foods: a randomized controlled clinical trial","volume":"17","author":"JK Anastasi","year":"2006","journal-title":"J Assoc Nurses AIDS Care"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1093\/cid\/cis544","article-title":"Etiology and pharmacologic management of noninfectious diarrhea in HIV-infected individuals in the highly active antiretroviral therapy era","volume":"55","author":"RD MacArthur","year":"2012","journal-title":"Clin Infect Dis"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1086\/313826","article-title":"Management of protease inhibitor-associated diarrhea","volume":"30","author":"DS Sherman","year":"2000","journal-title":"Clin Infect Dis"},{"year":"2006","key":"ref11","article-title":"Manual cl\u00ednico de alimenta\u00e7\u00e3o e nutri\u00e7\u00e3o na assist\u00eancia a adultos infectados pelo HIV"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1258\/ijsa.2008.008244","article-title":"Nausea and vomiting in HIV: a symptom review","volume":"19","author":"S Chubineh","year":"2008","journal-title":"Int J STD AIDS"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"95","DOI":"10.4103\/1319-3767.48965","article-title":"Gastrointestinal opportunistic infections in human immunodeficiency virus disease","volume":"15","author":"AA Anazi","year":"2009","journal-title":"Saudi J Gastroenterol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1089\/aid.2012.0119","article-title":"HIV\/AIDS-associated opportunistic protozoal diarrhea","volume":"29","author":"M Agholi","year":"2013","journal-title":"AIDS Res Hum Retroviruses"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"e677","DOI":"10.1016\/j.ijid.2012.05.1022","article-title":"Prevalence of opportunistic intestinal parasitic infections among HIV-infected patients with low CD4 cells counts in France in the combination antiretroviral therapy era","volume":"16","author":"J Pavie","year":"2012","journal-title":"Int J Infect Dis"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1111\/apt.13143","article-title":"Functional gastrointestinal disorders in 35,447 adults and their association with body mass index","volume":"41","author":"D Le Pluart","year":"2015","journal-title":"Aliment Pharmacol Ther"},{"key":"ref17","first-page":"57","article-title":"Gastrointestinal manifestations of the acquired immunodeficiency syndrome","volume":"146","author":"VD Rodgers","year":"1987","journal-title":"West J Med"},{"key":"ref18","first-page":"30","article-title":"Risk factors for gastrointestinal adverse events in HIV treated and untreated patients","volume":"11","author":"A Hill","year":"2009","journal-title":"AIDS Rev"},{"key":"ref19","first-page":"3382","article-title":"Diarrhea and abnormalities of gastrointestinal function in a cohort of men and women with HIV infection","volume":"95","author":"TA Knox","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1590\/1806-9282.62.04.353","article-title":"Overweight and abdominal obesity in adults living with HIV\/AIDS","volume":"64","author":"ACO Castro","year":"2016","journal-title":"Rev Assoc Med Bras"},{"issue":"16","key":"ref21","first-page":"S0261","article-title":"Effectiveness of nutritional treatment and synbiotic use on gastrointestinal symptoms reduction in HIV-infected patients: randomized clinical trial","author":"ASAC Santos","year":"2016","journal-title":"Clin Nutr"},{"key":"ref22","unstructured":"Organizaci\u00f3n Panamericana de la Salud. Protocolo y directrices: Conjunto de A\u00e7\u00f5es para la Reducci\u00f3n Multifactorial de Enfermedades no Transmisibles (9 CARMEN\/CINDI). OPAS; 1997."},{"key":"ref23","first-page":"1","article-title":"Sociedade Brasileira de Cardiologia. Sociedade Brasileira de Nefrologia","volume":"13","year":"2010","journal-title":"VI Diretrizes Brasileiras de Hipertens\u00e3o Arterial. Arq Bras Hipertens"},{"key":"ref24","unstructured":"IPAQ. Guidelines for data processing and analysis of the International Physical Activity Questionnaire (IPAQ): short and long forms. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/sites.google.com\/site\/theipaq\/scoring-protocol\" xlink:type=\"simple\">https:\/\/sites.google.com\/site\/theipaq\/scoring-protocol<\/ext-link>. Accessed 14 November 2013."},{"year":"2010","key":"ref25","article-title":"Antiretroviral therapy for HIV infection in adults and adolescents: recommendations for a public health approach"},{"article-title":"Anthropometric standardization reference manual","year":"1988","author":"TG Lohman","key":"ref26"},{"year":"1997","key":"ref27","article-title":"Obesity: preventing and managing the global epidemic"},{"year":"2011","key":"ref28","article-title":"Stata Statistical Software: Release 12"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ijpharm.2011.04.069","article-title":"Does sex matter? The influence of gender on gastrointestinal physiology and drug delivery","volume":"415","author":"AC Freire","year":"2011","journal-title":"Int J Pharm"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1300\/J013v12n02_07","article-title":"Sex differentials in health and mortality","volume":"12","author":"LM Verbrugge","year":"1987","journal-title":"Women Health"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0277-9536(98)00292-5","article-title":"Do women &quot;over-report&quot; morbidity? Men&apos;s and women&apos;s responses to structured prompting on a standard question on long standing illness","volume":"48","author":"S Macintyre","year":"1999","journal-title":"Soc Sci Med"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1136\/gut.2004.051821","article-title":"Epidemiology of gastro-oesophageal reflux disease: a systematic review","volume":"54","author":"J Dent","year":"2005","journal-title":"Gut"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.cgh.2006.09.016","article-title":"Time trends of gastroesophageal reflux disease: a systematic review","volume":"5","author":"HB El-Serag","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1111\/j.1572-0241.2002.05783.x","article-title":"Epidemiology and health care seeking in the functional GI disorders: a population-based study","volume":"97","author":"NA Koloski","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"ref35","first-page":"3","article-title":"Prevalence of upper gastrointestinal symptoms in the general population: a systematic review","volume":"231","author":"RC Heading","year":"1999","journal-title":"Scand J Gastroenterol Suppl"},{"key":"ref36","first-page":"5","article-title":"Nicotine and gastrointestinal disorders: its role in ulceration and cancer development","volume":"19","author":"KM Chu","year":"2013","journal-title":"Curr Pharm Des"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1023\/A:1026040723669","article-title":"Smoking and the pathogenesis of gastroduodenal ulcer\u2014recent mechanistic update","volume":"253","author":"P Maity","year":"2003","journal-title":"Mol Cell Biochem"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/ncpgasthep0316","article-title":"Mechanisms of disease: nicotine\u2014a review of its actions in the context of gastrointestinal disease","volume":"2","author":"GA Thomas","year":"2005","journal-title":"Nat Clin Pract Gastroenterol Hepatol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1590\/S0034-70942002000300012","article-title":"Implica\u00e7\u00f5es Anest\u00e9sicas do Tabagismo","volume":"52","author":"RD Furtado","year":"2002","journal-title":"Rev Bras Anestesiol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"160","DOI":"10.2174\/157016211795945241","article-title":"Prospective observation for seven-year\u2019s highly active antiretroviral therapy in Chinese HIV-1 Infected patients","volume":"9","author":"M He","year":"2011","journal-title":"Curr HIV Res"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s13181-013-0325-8","article-title":"A review of the toxicity of HIV medications","volume":"10","author":"AM Margolis","year":"2014","journal-title":"J Med Toxicol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1177\/0956462414533318","article-title":"Persistent HIV-related stigma among an outpatient US clinic population","volume":"26","author":"E Shacham","year":"2015","journal-title":"Int J STD AIDS"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/1471-2334-6-39","article-title":"Diarrhea, CD4 counts and enteric infections in a hospital\u2014based cohort of HIV-infected patients around Varanasi, India","volume":"6","author":"SV Attili","year":"2006","journal-title":"BMC Infect Dis"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/2050-6511-15-32","article-title":"Self-reported adverse drug reactions and their influence on highly active antiretroviral therapy in HIV-infected patients: a cross-sectional study","volume":"15","author":"WT Tadesse","year":"2014","journal-title":"BMC Pharmacol Toxicol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0164774","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T12:42:42Z","timestamp":1589028162000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0164774"}},"subtitle":[],"editor":[{"given":"Dimitrios","family":"Paraskevis","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,10,17]]},"references-count":44,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2016,10,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0164774","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2016,10,17]]}}}