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Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.paho.org\/hq\/index.php?option=com_docman&task=doc_download&gid=14164&Itemid=&lang=fr\" xlink:type=\"simple\">http:\/\/www.paho.org\/hq\/index.php?option=com_docman&amp;task=doc_download&amp;gid=14164&amp;Itemid=&amp;lang=fr<\/ext-link>"},{"issue":"Suppl 3","key":"ref7","doi-asserted-by":"crossref","first-page":"C114","DOI":"10.1016\/j.vaccine.2013.05.032","article-title":"Systematic documentation of new vaccine introduction in selected countries of the Latin American Region","volume":"31","author":"LH de Oliveira","year":"2013","journal-title":"Vaccine"},{"key":"ref8","first-page":"1","article-title":"Pneumococcal conjugate vaccine introduction in Latin America and the Caribbean: progress and lessons learned","author":"LH de Oliveira","year":"2016","journal-title":"Expert Rev Vaccines"},{"key":"ref9","year":"2016"},{"key":"ref10","author":"GS Wells","year":"2008"},{"key":"ref11","year":"2014"},{"issue":"4","key":"ref12","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1017\/S0266462303000576","article-title":"Interrupted time series designs in health technology assessment: lessons from two systematic reviews of behavior change strategies","volume":"19","author":"CR Ramsay","year":"2003","journal-title":"Int J Technol Assess Health Care"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/2046-4053-3-8","article-title":"Prosthetic heart valves in pregnancy: a systematic review and meta-analysis protocol","volume":"3","author":"CM Lawley","year":"2014","journal-title":"Syst Rev"},{"issue":"3","key":"ref14","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1093\/ije\/dym018","article-title":"Tools for assessing quality and susceptibility to bias in observational studies in epidemiology: a systematic review and annotated bibliography","volume":"36","author":"S Sanderson","year":"2007","journal-title":"Int J Epidemiol"},{"issue":"6","key":"ref15","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/S2213-2600(14)70060-8","article-title":"Effectiveness of ten-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in Brazil: a matched case-control study","volume":"2","author":"CM Domingues","year":"2014","journal-title":"Lancet Respir Med"},{"key":"ref16","article-title":"Indirect cohort analysis of 10-valent pneumococcal conjugate vaccine effectiveness against vaccine-type and vaccine-related invasive pneumococcal disease","author":"JR Verani","year":"2015","journal-title":"Vaccine"},{"issue":"6","key":"ref17","doi-asserted-by":"crossref","first-page":"e98567","DOI":"10.1371\/journal.pone.0098567","article-title":"Impact of pneumococcal conjugate vaccines on the incidence of pneumonia in hospitalized children after five years of its introduction in Uruguay","volume":"9","author":"M Hortal","year":"2014","journal-title":"PLoS One"},{"issue":"1","key":"ref18","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4236\/wjv.2015.51005","article-title":"Effect of 7 and 13-valent pneumococcal conjugate vaccines different number of doses for pneumonia control in 2008 and 2010 Birth Cohort Children Uruguay","volume":"5","author":"M Hortal","year":"2015","journal-title":"World J Vaccines"},{"issue":"2","key":"ref19","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.jped.2014.07.002","article-title":"Pneumococcal meningitis: epidemiological profile pre- and post-introduction of the pneumococcal 10-valent conjugate vaccine","volume":"91","author":"TE Hirose","year":"2015","journal-title":"J Pediatr (Rio J)"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1590\/0102-311X00169913","article-title":"Impact of 10-valent pneumococcal conjugate vaccine on pneumococcal meningitis in children up to two years of age in Brazil","volume":"31","author":"IM Grando","year":"2015","journal-title":"Cad Saude Publica"},{"issue":"6","key":"ref21","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1097\/INF.0000000000000269","article-title":"Changes in childhood pneumonia and infant mortality rates following introduction of the 13-valent pneumococcal conjugate vaccine in Nicaragua","volume":"33","author":"S Becker-Dreps","year":"2014","journal-title":"Pediatr Infect Dis J"},{"issue":"4","key":"ref22","doi-asserted-by":"crossref","first-page":"e0153141","DOI":"10.1371\/journal.pone.0153141","article-title":"Effectiveness of the 10-valent pneumococcal conjugate vaccine (pcv-10) in children in Chile: a nested case-control study using Nationwide Pneumonia Morbidity and Mortality Surveillance Data","volume":"11","author":"J Diaz","year":"2016","journal-title":"PLoS One"},{"key":"ref23","unstructured":"Minamisava R, Sgambatti S, Morais-Neto OL, Cristo EB, Escalante JJC, Bierrenbach AL, et al. Impact of PCV10 introduction on pneumonia mortality rates in Brazil: a time series analysis. Poster Session Pneumococcal Pneumonia\u2014Risky Business at: 9th International Symposium on Pneumococci and Pneumococcal Diseases; 2014 Mar 9\u201313; Hyderabad, India. Poster 0556. 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Poster Session at: 33rd Annual European Society for Paediatric Infectious Diseases Meeting; 2015 May 12\u201316. Leipzig, Germany; 2015 [cited 2016 Jul 7];. Poster 0808, p. 1101. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/espid2015.kenes.com\/Documents\/ESPID%202015%20Abstracts.pdf\" xlink:type=\"simple\">http:\/\/espid2015.kenes.com\/Documents\/ESPID%202015%20Abstracts.pdf<\/ext-link>"},{"issue":"35","key":"ref27","doi-asserted-by":"crossref","first-page":"4495","DOI":"10.1016\/j.vaccine.2014.06.042","article-title":"Impact of 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) on childhood pneumonia hospitalizations in Brazil two years after introduction","volume":"32","author":"MC Scotta","year":"2014","journal-title":"Vaccine"},{"issue":"5","key":"ref28","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.vaccine.2015.12.007","article-title":"Early impact of 10-valent pneumococcal conjugate vaccine in childhood pneumonia hospitalizations using primary data from an active population-based surveillance","volume":"34","author":"S Sgambatti","year":"2016","journal-title":"Vaccine"},{"issue":"17","key":"ref29","first-page":"45","article-title":"Notificaci\u00f3n de neumon\u00edas y meningitis en ni\u00f1os despu\u00e9s de la introducci\u00f3n de la vacuna antineumoc\u00f3cica conjugada al calendario nacional de vacunaci\u00f3n","volume":"4","author":"A Gaiano","year":"2013","journal-title":"Rev Argent Salud Publica"},{"issue":"6","key":"ref30","first-page":"502","article-title":"Impact of the 13-valent pneumococcal conjugate vaccine on the incidence of consolidated pneumonia in children younger than 5 years old in Pilar, Buenos Aires: A population-based study","volume":"113","author":"A Gentile","year":"2015","journal-title":"Arch Argent Pediatr"},{"key":"ref31","unstructured":"Rearte A, Ruvinsky R, Kupervase J, Gentile AF, Fosati S, Regueira M, et al. Population-based surveillance: incidence of consolidated pneumonia and pneumococcal disease in children of Concordia, Argentina. Comparison with the pre- 13-valent pneumococcal vaccine (PCV-13) routine immunization period. Paper presented at: 9th World Conference of the World Society for Pediatric Infectious Diseases; 2015 Nov 18\u201321; Rio de Janeiro, Brazil, 2015 [cited 2016 Jul 7]. Abst 0420, p. 73. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/wspid.kenes.com\/Documents\/WSPID%20All%20Abstracts.pdf\" xlink:type=\"simple\">http:\/\/wspid.kenes.com\/Documents\/WSPID%20All%20Abstracts.pdf<\/ext-link>"},{"issue":"2","key":"ref32","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1080\/21645515.2015.1117713","article-title":"Evaluating the impact of PCV-10 on invasive pneumococcal disease in Brazil: a time-series analysis","volume":"12","author":"AL Andrade","year":"2016","journal-title":"Hum Vaccin Immunother"},{"key":"ref33","unstructured":"Becker-Dreps S, Amaya E, Liu L, Moreno G, Rocha J, Brice\u00f1o R, et al. Impact of a pediatric PCV-13 immunization program on hospitalizations and outpatient visits for pneumonia in Nicaragua. Poster Session: Pneumococcal Vaccine in Children and Adults at: IDWeek 2013; 2013 Oct 2\u20136; San Francisco, California; 2013 [cited 2016 Jul 7]. Poster 448, p. 319. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/idsa.confex.com\/idsa\/2013\/webprogram\/Paper40289.html\" xlink:type=\"simple\">https:\/\/idsa.confex.com\/idsa\/2013\/webprogram\/Paper40289.html<\/ext-link>"},{"key":"ref34","unstructured":"Hortal M, Laurani H, Meny M, Estevan M, Arrieta F. Effectiveness of 7 and 13-valent pneumococcal conjugate vaccines for consolidated pneumonia in hospitalized children. Paper presented at: 9th International Symposium on Pneumococci and Pneumococcal Diseases; 2014 Mar 9\u201313; Hyderabad, India. Poster 0059. (Pneumonia 2014, vol 3, Special issue, p. 142)."},{"key":"ref35","unstructured":"Sgambatti S, Minamisava R, Vieira MA, Toscano CM, Bierrenbach AL, Andrade AL. Using primary data to assess pneumonia hospitalization rates 3 years before and after PCV10 introduction in Brazil. Poster Session at: 32nd Annual European Society for Paediatric Infectious Diseases Meeting; 2014 May 6\u201310; Dublin, Ireland; 2014 [cited 2016 Jul 7]. Abst. 491. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/cmoffice.kenes.com\/cddemo\/data\/HtmlApp\/main.html\" xlink:type=\"simple\">http:\/\/cmoffice.kenes.com\/cddemo\/data\/HtmlApp\/main.html<\/ext-link>"},{"key":"ref36","unstructured":"Pinto L, Veras T, Scotta M, Tronco V, Klein P, Daudt A, et al. Impact of introducing the 10-valent pneumococcal conjugate vaccine on childhood hospitalizations for bacterial pneumonia in Brazil. Poster session: Pediatric Respiratory Epidemioloy at: 23rd Annual Congress European Respiratory Society; 2013 Set 7\u201311; Barcelona, Spain; 2013 [cited 2016 Jul 7]. Poster P4324. (European Respiratory Journal 2013, vol 42, Suppl 57, p. 924). Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/lrp.ersnet.org\/\/abstract_print_13\/files\/Abstract_book_2013.pdf\" xlink:type=\"simple\">http:\/\/lrp.ersnet.org\/\/abstract_print_13\/files\/Abstract_book_2013.pdf<\/ext-link>"},{"key":"ref37","unstructured":"Gentile A, Bakir J, Bialorus L, Caruso L, Fernandez MI, Mirra D, et al. Effectiveness of PCV13 vaccine to prevent consolidated pneumonia: population-based study in children under 5 years. Poster session: Pediatric Bacterial Infections at: IDWeek 2015; 2015 Oct 7\u201311; San Diego, California; 2015 [cited 2016 Jul 7]. Poster 1765, p. 1234. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/idsa.confex.com\/idsa\/2015\/webprogram\/Paper51940.html\" xlink:type=\"simple\">https:\/\/idsa.confex.com\/idsa\/2015\/webprogram\/Paper51940.html<\/ext-link>"},{"key":"ref38","unstructured":"Gentile A, J., Bakir L, Bialorus L, Caruso M, Fern\u00e1ndez D, Mirra D, et al. Introduction of the PCV13 in Argentina: assessment of effectiveness to prevent consolidated pneumonia in children. Poster session: Controlling Pneumococcal Disease Around the Globe presented at: 9th International Symposium on Pneumococci and Pneumococcal Diseases; 2014 Mar 9\u201313; Hyderabad, India. Poster 0212. (Pneumonia 2014, vol. 3, Special issue, p. 168)"},{"key":"ref39","unstructured":"Vizzotti C, Ranca\u00f1o C, Juarez M, Sagradini S, Gaiano A, Neyro S, et al. Argentinas experience 2 years after universal PCV 13 introduction: the importance of a national epidemiological surveillance system to monitoring a vaccination strategy. Poster session: Global Pneumococcal Disease and Policies for Control at: 9th International Symposium on Pneumococci and Pneumococcal Diseases; 2014 Mar 9\u201313; Hyderabad, India. Poster 0518. (Pneumonia 2014, vol. 3, Special issue, p. 243)."},{"key":"ref40","unstructured":"Vizzotti C, Rearte A, Juarez M, Ranca\u00f1o C, Sagradini S, Gaiano A, et al. Universal vaccination with PCV13 in Argentina: time series analysis 2008\u20132013 of bacterial pneumonia admissions in children under 5 years old. Poster session: Global Pneumococcal Disease and Policies for Control at: 9th International Symposium on Pneumococci and Pneumococcal Diseases; 2014 Mar 9\u201313; Hyderabad, India. Poster 0517. (Pneumonia 2014, vol. 3, Special issue, p. 244)."},{"key":"ref41","unstructured":"Azevedo J, Santos M, Silva M, Leite C, Pedrosa M, Cordeiro S, et al. Progressive changes in pneumococcal meningitis in a large urban center in brazil after 4 years of 10-valent pneumococcal conjugate vaccine (PCV10) introduction. Paper presented at: 115th Annual Meeting of the American Society for Microbiology; 2015 May 30-Jun 2; New Orleans, Louisiana, USA. Poster 2284."},{"key":"ref42","unstructured":"Liphaus B, Okay MIG, Yu ALF, Ribeiro AF, Carvalhanas TRMP, Safadi MAP. Decline in pneumococcal meningitis after introduction of 10-valent pneumococcal conjugate vaccine in S\u00e3o Paulo, Brazil. Paper presented at: 8th International Symposium on Pneumococci and Pneumococcal Disease; 2012 March 11\u201315; Igua\u00e7u Falls, Brazil; 2012 [cited 2016 Jul 7]. Poster 322, p. 619. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www2.kenes.com\/ISPPD\/Scientific\/Documents\/FinalAbstractbook.pdf\" xlink:type=\"simple\">http:\/\/www2.kenes.com\/ISPPD\/Scientific\/Documents\/FinalAbstractbook.pdf<\/ext-link>"},{"key":"ref43","unstructured":"Domingues C, Verani JR, Montenegro ER, Brandileone MCC, Flannery B, Oliveira LH, et al. Effectiveness of ten-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in Brazil: a matched case-control study. Poster session: Controlling Pneumococcal Disease Around the Globe at: 9th International Symposium on Pneumococci and Pneumococcal Diseases; 2014 Mar 9\u201313; Hyderabad, India. Poster 0288. (Pneumonia 2014, vol. 3, Special issue, p. 145)."},{"issue":"11","key":"ref44","doi-asserted-by":"crossref","first-page":"e112337","DOI":"10.1371\/journal.pone.0112337","article-title":"Effect of pneumococcal conjugate vaccination in Uruguay, a middle-income country","volume":"9","author":"G Garcia Gabarrot","year":"2014","journal-title":"PLoS One"},{"issue":"6","key":"ref45","doi-asserted-by":"crossref","first-page":"651","DOI":"10.4067\/S0716-10182014000600002","article-title":"Vigilancia de laboratorio de Streptococcus pneumoniae procedente de enfermedad invasora, Chile 2007\u20132012","volume":"31","author":"MT Valenzuela","year":"2014","journal-title":"Rev Chilena Infectol"},{"issue":"7","key":"ref46","first-page":"1","article-title":"Vigilancia de laboratorio de streptococcus pneumoniae procedente de enfermedad invasora. Chile, 2007\u20132015","volume":"5","year":"2015","journal-title":"Bol Inst Salud Pubica Chile"},{"key":"ref47","unstructured":"Andrade AL, Minamisava EB, Policena G, Cristo EB, Morais-Neto OL, Domingues CMAS, et al. Effect of 10-valent pneumococcal conjugate vaccine on meningitis and invasive disease after 3 years of routine immunization in Brazil. Paper presented at: 33rd Annual European Society for Paediatric Infectious Diseases Meeting; 2015 May 12\u201316. Leipzig, Germany; 2015 [cited 2016 Jul 7]. Abst. 0915, p. 250. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/espid2015.kenes.com\/Documents\/ESPID%202015%20Abstracts.pdf\" xlink:type=\"simple\">http:\/\/espid2015.kenes.com\/Documents\/ESPID%202015%20Abstracts.pdf<\/ext-link>."},{"issue":"1","key":"ref48","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/oxfordjournals.epirev.a017988","article-title":"Use of the case-control approach in vaccine evaluation: efficacy and adverse effects","volume":"21","author":"LC Rodrigues","year":"1999","journal-title":"Epidemiol Rev"},{"issue":"9","key":"ref49","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1093\/oxfordjournals.aje.a116398","article-title":"Selection of controls in case-control studies. III. Design options","volume":"135","author":"S Wacholder","year":"1992","journal-title":"Am J Epidemiol"},{"issue":"6","key":"ref50","doi-asserted-by":"crossref","first-page":"e98128","DOI":"10.1371\/journal.pone.0098128","article-title":"Direct effect of 10-valent conjugate pneumococcal vaccination on pneumococcal carriage in children Brazil","volume":"9","author":"AL Andrade","year":"2014","journal-title":"PLoS One"},{"issue":"25","key":"ref51","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1016\/j.vaccine.2016.04.006","article-title":"Impact of the introduction of the pneumococcal conjugate vaccine in the Brazilian routine childhood national immunization program","volume":"34","author":"M Moreira","year":"2016","journal-title":"Vaccine"},{"issue":"Suppl. 2","key":"ref52","first-page":"S140","article-title":"Systematic review of the effect of pneumococcal conjugate vaccine dosing schedules on prevention of pneumonia","volume":"33","author":"JD Loo","year":"2014","journal-title":"Pediatr Infect Dis J"},{"issue":"4","key":"ref53","first-page":"Cd004977","article-title":"Pneumococcal conjugate vaccines for preventing vaccine-type invasive pneumococcal disease and X-ray defined pneumonia in children less than two years of age","author":"MG Lucero","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"ref54","first-page":"010401","article-title":"Epidemiology and etiology of childhood pneumonia in 2010: estimates of incidence, severe morbidity, mortality, underlying risk factors and causative pathogens for 192 countries","volume":"3","author":"I Rudan","year":"2013","journal-title":"J Glob Health"},{"issue":"12","key":"ref55","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1001\/archpedi.161.12.1162","article-title":"Health care utilization for pneumonia in young children after routine pneumococcal conjugate vaccine use in the United States","volume":"161","author":"F Zhou","year":"2007","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"9465","key":"ref56","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/S0140-6736(05)71876-6","article-title":"Efficacy of nine-valent pneumococcal conjugate vaccine against pneumonia and invasive pneumococcal disease in The Gambia: randomised, double-blind, placebo-controlled trial","volume":"365","author":"FT Cutts","year":"2005","journal-title":"Lancet"},{"issue":"36","key":"ref57","doi-asserted-by":"crossref","first-page":"4623","DOI":"10.1016\/j.vaccine.2015.06.062","article-title":"Impact of PCV7\/PCV13 introduction on community-acquired alveolar pneumonia in children &lt;5 years","volume":"33","author":"D Greenberg","year":"2015","journal-title":"Vaccine"},{"issue":"8","key":"ref58","doi-asserted-by":"crossref","first-page":"e0135270","DOI":"10.1371\/journal.pone.0135270","article-title":"Impact of Pneumococcal Conjugate Vaccine Administration in Pediatric Older Age Groups in Low and Middle Income Countries: A Systematic Review","volume":"10","author":"K Bonner","year":"2015","journal-title":"PLoS One"},{"issue":"14","key":"ref59","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2016.21.14.30186","article-title":"Direct, indirect and total effects of 13-valent pneumococcal conjugate vaccination on invasive pneumococcal disease in children in Navarra, Spain, 2001 to 2014: cohort and case-control study","volume":"21","author":"M Guevara","year":"2016","journal-title":"Euro Surveill"},{"issue":"1","key":"ref60","doi-asserted-by":"crossref","first-page":"e22","DOI":"10.1542\/peds.2015-0458","article-title":"Pneumococcal conjugate vaccine and clinically suspected invasive pneumococcal disease","volume":"136","author":"AA Palmu","year":"2015","journal-title":"Pediatrics"},{"issue":"10","key":"ref61","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1586\/14760584.2015.1075884","article-title":"The impact of 10-valent and 13-valent pneumococcal conjugate vaccines on serotype 19A invasive pneumococcal disease","volume":"14","author":"N Principi","year":"2015","journal-title":"Expert Rev Vaccines"},{"issue":"Pt 1","key":"ref62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1099\/jmm.0.020016-0","article-title":"Continued control of pneumococcal disease in the UK\u2014the impact of vaccination","volume":"60","author":"RA Gladstone","year":"2011","journal-title":"J Med Microbiol"},{"key":"ref63","unstructured":"Russell F, Sanderson C, Temple B, Henao-Restrepo AM, Mulholland K. Global review of the distribution of pneumococcal disease by age and region: implications for vaccination schedules. Paper presented at: 8th International Symposium on Pneumococci and Pneumococcal Disease; 2012 March 11\u201315; Igua\u00e7u Falls, Brazil; 2012 [cited 2016 Jul 7]. Poster 41, p. 352. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www2.kenes.com\/ISPPD\/Scientific\/Documents\/FinalAbstractbook.pdf\" xlink:type=\"simple\">http:\/\/www2.kenes.com\/ISPPD\/Scientific\/Documents\/FinalAbstractbook.pdf<\/ext-link>"},{"issue":"48","key":"ref64","doi-asserted-by":"crossref","first-page":"5634","DOI":"10.1016\/j.vaccine.2013.07.006","article-title":"Vaccine effects and impact of vaccination programmes in post-licensure studies","volume":"31","author":"G Hanquet","year":"2013","journal-title":"Vaccine"},{"key":"ref65","doi-asserted-by":"crossref","DOI":"10.1590\/S0034-8910.2015049006058","article-title":"Methods and challenges for the health impact assessment of vaccination programs in Latin America","volume":"49","author":"AM Sartori","year":"2015","journal-title":"Rev Saude Publica"},{"key":"ref66","article-title":"Cochrane handbook for systematic reviews of interventions","author":"JAC Sterne","year":"2008"},{"issue":"11","key":"ref67","doi-asserted-by":"crossref","first-page":"e112211","DOI":"10.1371\/journal.pone.0112211","article-title":"All-cause pneumonia hospitalizations in children &lt;2 years old in sweden, 1998 to 2012: impact of pneumococcal conjugate vaccine introduction","volume":"9","author":"A Berglund","year":"2014","journal-title":"PLoS One"},{"issue":"23","key":"ref68","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1016\/j.vaccine.2015.04.005","article-title":"Effectiveness of three pneumococcal conjugate vaccines to prevent invasive pneumococcal disease in Quebec, Canada","volume":"33","author":"G Deceuninck","year":"2015","journal-title":"Vaccine"},{"key":"ref69","unstructured":"Pan American Health Organization. Technical Advisory Group on Vaccine-preventable Diseases, editor. Final report of the 23th TAG Meeting; 2015 1\u20133 July; Varadero, Cuba. Washington, DC: PAHO, 2015 [cited 2016 Jul 5]. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.paho.org\/hq\/index.php?option=com_docman&task=doc_download&gid=31233&Itemid=270&lang=fr\" xlink:type=\"simple\">http:\/\/www.paho.org\/hq\/index.php?option=com_docman&amp;task=doc_download&amp;gid=31233&amp;Itemid=270&amp;lang=fr<\/ext-link>"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0166736","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T11:25:42Z","timestamp":1589714742000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0166736"}},"subtitle":[],"editor":[{"given":"Ray","family":"Borrow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,12,12]]},"references-count":69,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2016,12,12]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0166736","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,12]]}}}