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R package version 0.84. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/CRAN.R-project.org\/package=irr\" xlink:type=\"simple\">https:\/\/CRAN.R-project.org\/package=irr<\/ext-link>."},{"issue":"7","key":"ref41","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1590\/S0100-736X2014000700013","article-title":"Hematological and histopathological evaluation of wildlife green turtles (<italic>Chelonia mydas<\/italic>) with and without fibropapilloma from the north coast of S\u00e3o Paulo State, Brazil","volume":"34","author":"T Zwarg","year":"2014","journal-title":"Pesquisa Veterin\u00e1ria Brasileira"},{"key":"ref42","unstructured":"Tapia AC. Evaluaci\u00f3n histopatol\u00f3gica de las etiolog\u00edas comunes y asociadas a fibropapiloma en la tortuga prieta (Chelonia mydas agassizii) de Bah\u00eda Magdalena, Baja California Sur, M\u00e9xico. PhD Thesis. Centro de Investigaciones Biol\u00f3gicas de Noroeste, La Paz. 2004."},{"issue":"3","key":"ref43","first-page":"84","article-title":"Release and recapture of captive-reared green sea turtles, <italic>Chelonia mydas<\/italic>, in the waters surrounding Cayman Islands","volume":"3","author":"F Wood","year":"1993","journal-title":"Herpetological Journal"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3354\/dao02878","article-title":"Case descriptions of fibropapillomatosis in rehabilitating loggerhead sea turtles <italic>Caretta caretta<\/italic> in Southeastern USA","volume":"115","author":"A Page-Karjian","year":"2015","journal-title":"Diseases of Aquatic Organisms"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s005800070004","article-title":"Blood biochemistry values of green turtles, <italic>Chelonia mydas<\/italic>, with and without fibropapillomatosis","volume":"10","author":"AA Aguirre","year":"2000","journal-title":"Comparative Haematology International"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3354\/dao053041","article-title":"Bacteraemia in free-ranging Hawaiian green turtles <italic>Chelonia mydas<\/italic> with fibropapillomatosis","volume":"53","author":"TM Work","year":"2003","journal-title":"Diseases of Aquatic Organisms"},{"issue":"2","key":"ref47","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1017\/S0025315409990579","article-title":"Juvenile green turtles (<italic>Chelonia mydas<\/italic>) in the effluent discharge channel of a steel plant, Esp\u00edrito Santo, Brazil, 2000\u20132006","volume":"90","author":"E Torezani","year":"2010","journal-title":"Journal of Marine Biological Association of United Kingdom"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0167632","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T23:34:39Z","timestamp":1540337679000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0167632"}},"subtitle":[],"editor":[{"given":"Christopher D.","family":"Marshall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,12,9]]},"references-count":47,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2016,12,9]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0167632","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,9]]}}}