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China 2010 population census data Beijing: National Bureau of Statistics of the People&apos;s Republic of China; 2012. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.stats.gov.cn\/tjsj\/pcsj\/rkpc\/6rp\/indexch.htm\" xlink:type=\"simple\">http:\/\/www.stats.gov.cn\/tjsj\/pcsj\/rkpc\/6rp\/indexch.htm<\/ext-link>."},{"key":"ref3","unstructured":"The United Nations Children&apos;s Fund. Levels and trends in child mortality. Report 2015. Estimates developed by the UN Inter-agency Group for Child Mortality Estimation. 2015 September 2015. p. 19."},{"issue":"9882","key":"ref4","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1016\/S0140-6736(13)61097-1","article-title":"Rapid health transition in China, 1990\u20132010: findings from the Global Burden of Disease Study 2010","volume":"381","author":"G Yang","year":"2013","journal-title":"Lancet"},{"issue":"9720","key":"ref5","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0140-6736(10)60060-8","article-title":"Causes of deaths in children younger than 5 years in China in 2008","volume":"375","author":"I Rudan","year":"2010","journal-title":"Lancet"},{"issue":"9947","key":"ref6","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/S0140-6736(14)60497-9","article-title":"Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990\u20132013: a systematic analysis for the Global Burden of Disease Study 2013","volume":"384","author":"H Wang","year":"2014","journal-title":"Lancet"},{"issue":"9801","key":"ref7","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/S0140-6736(11)61096-9","article-title":"China&apos;s facility-based birth strategy and neonatal mortality: a population-based epidemiological study","volume":"378","author":"XL Feng","year":"2011","journal-title":"Lancet"},{"issue":"3 Pt 1","key":"ref8","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1542\/peds.101.3.398","article-title":"United States neonatology practice survey: personnel, practice, hospital, and neonatal intensive care unit characteristics","volume":"101","author":"LD Pollack","year":"1998","journal-title":"Pediatrics"},{"issue":"5","key":"ref9","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1542\/peds.106.5.1070","article-title":"Variations in practice and outcomes in the Canadian NICU network: 1996\u20131997","volume":"106","author":"SK Lee","year":"2000","journal-title":"Pediatrics"},{"issue":"1","key":"ref10","first-page":"15","article-title":"Epidemiologic survey on hospitalized neonates in China","volume":"1","author":"K-L Wei","year":"2012","journal-title":"Translational Pediatrics"},{"issue":"5","key":"ref11","first-page":"326","article-title":"Present situation of neonatal subspecialty in the mainland of China: a survey based on 109 hospitals","volume":"50","author":"ZC Feng","year":"2012","journal-title":"Chinese Journal of Pediatrics"},{"issue":"003","key":"ref12","first-page":"238","article-title":"Classification, construction and management of neonatal wards in China (Recommendation)","volume":"28","author":"ZC Feng","year":"2013","journal-title":"Chinese Journal of Applied Clinical Pediatrics"},{"issue":"5","key":"ref13","doi-asserted-by":"crossref","first-page":"F440","DOI":"10.1136\/archdischild-2012-302524","article-title":"Neonatal-perinatal medicine in a transitional period in China","volume":"98","author":"B Sun","year":"2013","journal-title":"Archives of disease in childhood Fetal and neonatal edition"},{"issue":"5","key":"ref14","first-page":"321","article-title":"Development course of neonatal medicine in China","volume":"53","author":"LZ Du","year":"2015","journal-title":"Chinese Journal of Pediatrics"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"e731","DOI":"10.1542\/peds.2011-0725","article-title":"Morbidity and mortality of neonatal respiratory failure in China: surfactant treatment in very immature infants","volume":"129","author":"H Wang","year":"2012","journal-title":"Pediatrics"},{"issue":"5","key":"ref16","doi-asserted-by":"crossref","first-page":"e1115","DOI":"10.1542\/peds.2006-2426","article-title":"Neonatal respiratory failure: a 12-month clinical epidemiologic study from 2004 to 2005 in China","volume":"121","author":"L Qian","year":"2008","journal-title":"Pediatrics"},{"issue":"9966","key":"ref17","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/S0140-6736(14)61698-6","article-title":"Global, regional, and national causes of child mortality in 2000\u201313, with projections to inform post-2015 priorities: an updated systematic analysis","volume":"385","author":"L Liu","year":"2015","journal-title":"Lancet"},{"issue":"9735","key":"ref18","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0140-6736(10)61073-2","article-title":"Causes of death in children younger than 5 years in China in 2008","volume":"376","author":"K Mulholland","year":"2010","journal-title":"Lancet"},{"issue":"10015","key":"ref19","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0140-6736(15)00554-1","article-title":"Under-5 mortality in 2851 Chinese counties, 1996\u20132012: a subnational assessment of achieving MDG 4 goals in China","volume":"387","author":"Y Wang","year":"2016","journal-title":"Lancet"},{"issue":"6","key":"ref20","first-page":"141","article-title":"Design of high-available integration platform for hospital information system","volume":"6","author":"ZQ Wen","year":"2009","journal-title":"Computer and modernization"},{"key":"ref21","unstructured":"Human Development Index, 2010. 2013 China National Human Development Report. United Nations Development Programme China. Beijing 2013. p. 105."},{"key":"ref22","unstructured":"Organisation for Economic Co-operation Development Staff. Health at a Glance. The Organisation for Economic Co-operation and Development. Paris; 2005."},{"issue":"3","key":"ref23","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/0196-6553(88)90053-3","article-title":"CDC definitions for nosocomial infections, 1988","volume":"16","author":"JS Garner","year":"1988","journal-title":"American journal of infection control"},{"key":"ref24","article-title":"Practice of Neonatology","author":"HZ Jing","year":"2002"},{"key":"ref25","unstructured":"Caserta MT. Neonatal pneumonia: Merck Publishing; 2015 [cited 2015 October 2015]. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.msdmanuals.com\/professional\/pediatrics\/infections-in-neonates\/neonatal-pneumonia\" xlink:type=\"simple\">http:\/\/www.msdmanuals.com\/professional\/pediatrics\/infections-in-neonates\/neonatal-pneumonia<\/ext-link>."},{"key":"ref26","unstructured":"Caserta MT. Neonatal sepsis: Merck Publishing; 2015 [cited 2015 October 2015]. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.msdmanuals.com\/professional\/pediatrics\/infections-in-neonates\/neonatal-pneumonia\" xlink:type=\"simple\">http:\/\/www.msdmanuals.com\/professional\/pediatrics\/infections-in-neonates\/neonatal-pneumonia<\/ext-link>."},{"key":"ref27","unstructured":"Kendig JW, Nawab U. Respiratory Distress Syndrome in Neonates: Merck Publishing; 2015 [cited 2015 January 2015]. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.msdmanuals.com\/professional\/pediatrics\/perinatal-problems\/respiratory-distress-syndrome-in-neonates\" xlink:type=\"simple\">http:\/\/www.msdmanuals.com\/professional\/pediatrics\/perinatal-problems\/respiratory-distress-syndrome-in-neonates<\/ext-link>."},{"key":"ref28","unstructured":"National Bureau of Statistics of China. China population and employment statistics yearbook 2013 China Statistics Press; 2014."},{"issue":"5","key":"ref29","first-page":"355","article-title":"Successful treatment and follow-up of one 500 gram extremely low birth weight infant","author":"G Xi-rong","year":"2009","journal-title":"Chinese Journal of Perinatal Medicine"},{"key":"ref30","unstructured":"30th anniversary of Neonatal Intensive Care Unit at Children&apos;s Hospital of Zhejiang University and celebration by dozens of internationally renowned experts in Hangzhou 2015 [cited 2015 2015-10-16]. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.zjuch.cn\/Html\/News\/Articles\/4840.html\" xlink:type=\"simple\">http:\/\/www.zjuch.cn\/Html\/News\/Articles\/4840.html<\/ext-link>."},{"issue":"9","key":"ref31","first-page":"669","article-title":"Coordination Group for National Survey of Development in Pediatric and Neonatal Intensive Care Units. Development of pediatric and neonatal intensive care units: results of a national survey (2000\u20132009)","volume":"49","author":"Y Zhang","year":"2011","journal-title":"Chinese medical journal"},{"issue":"9","key":"ref32","first-page":"649","article-title":"Emergency use of extracorporeal membrane oxygenation in pediatric critically ill patients","volume":"50","author":"R Lin","year":"2012","journal-title":"Chinese Journal of Pediatrics"},{"issue":"8","key":"ref33","first-page":"1448","article-title":"Impact of a nationwide training program for neonatal resuscitation in China","volume":"125","author":"T Xu","year":"2012","journal-title":"Chinese medical journal"},{"key":"ref34","unstructured":"The International Training Program in Neonatal-Perinatal Medicine in Shanghai 2004. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.canadianneonatalnetwork.org\/portal\/CNNHome\/TrainingProgram.aspx\" xlink:type=\"simple\">http:\/\/www.canadianneonatalnetwork.org\/portal\/CNNHome\/TrainingProgram.aspx<\/ext-link>."},{"key":"ref35","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/1472-6920-12-44","article-title":"Acute Care of At-Risk Newborns (ACoRN): quantitative and qualitative educational evaluation of the program in a region of China","volume":"12","author":"N Singhal","year":"2012","journal-title":"BMC medical education"},{"issue":"12","key":"ref36","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1007\/s13312-013-0305-8","article-title":"Predictors of mortality and major morbidities in extremely low birth weight neonates","volume":"50","author":"K Mukhopadhyay","year":"2013","journal-title":"Indian pediatrics"},{"issue":"1","key":"ref37","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s12098-012-0818-5","article-title":"Mortality and morbidity in extremely low birth weight (ELBW) infants in a neonatal intensive care unit","volume":"80","author":"A Tagare","year":"2013","journal-title":"Indian journal of pediatrics"},{"key":"ref38","unstructured":"First successfully treatment of an extremely preterm with 24 weeks of gestional age and a birth weight of 500 grams in China by Shengzhen Maternity and Child Healthcare Hospital 2015 [cited 2015 November 12 2015]. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.szmch.net.cn\/Search\/news\/371.html\" xlink:type=\"simple\">http:\/\/www.szmch.net.cn\/Search\/news\/371.html<\/ext-link>."},{"issue":"5","key":"ref39","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1542\/peds.113.5.1223","article-title":"Changes in mortality for extremely low birth weight infants in the 1990s: implications for treatment decisions and resource use","volume":"113","author":"W Meadow","year":"2004","journal-title":"Pediatrics"},{"issue":"2","key":"ref40","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1542\/peds.2008-0763","article-title":"Mortality rates for extremely low birth weight infants born in Japan in 2005","volume":"123","author":"K Itabashi","year":"2009","journal-title":"Pediatrics"},{"issue":"5","key":"ref41","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.puhe.2011.01.003","article-title":"Mortality rate for children under 5 years of age in China from 1996 to 2006","volume":"125","author":"YP Wang","year":"2011","journal-title":"Public health"},{"issue":"2","key":"ref42","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.siny.2013.11.002","article-title":"Long-term outcome for the tiniest or most immature babies: survival rates","volume":"19","author":"LK Smith","year":"2014","journal-title":"Seminars in fetal & neonatal medicine"},{"issue":"2","key":"ref43","doi-asserted-by":"crossref","first-page":"147.e1","DOI":"10.1016\/j.ajog.2006.09.014","article-title":"Trends in neonatal morbidity and mortality for very low birthweight infants","volume":"196","author":"AA Fanaroff","year":"2007","journal-title":"American journal of obstetrics and gynecology"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1471-2431-5-40","article-title":"Actuarial survival of a large Canadian cohort of preterm infants","volume":"5","author":"HP Jones","year":"2005","journal-title":"BMC pediatrics"},{"issue":"9818","key":"ref45","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0140-6736(12)60278-5","article-title":"Trends in access to health services and financial protection in China between 2003 and 2011: a cross-sectional study","volume":"379","author":"Q Meng","journal-title":"The Lancet"},{"issue":"6","key":"ref46","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1542\/peds.2014-1377","article-title":"Chinese pediatricians face a crisis: should they stay or leave?","volume":"134","author":"W Xu","year":"2014","journal-title":"Pediatrics"},{"issue":"9921","key":"ref47","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/S0140-6736(14)60482-7","article-title":"Shortage of paediatricians in China","volume":"383","author":"KJ Hu","year":"2014","journal-title":"Lancet"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.socscimed.2013.08.006","article-title":"Child health security in China: a survey of child health insurance coverage in diverse areas of the country","volume":"97","author":"J Xiong","year":"2013","journal-title":"Social science & medicine (1982)"},{"issue":"7","key":"ref49","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1164\/ajrccm.164.7.2012126","article-title":"Epidemiology of neonatal respiratory failure in the United States: projections from California and New York","volume":"164","author":"DC Angus","year":"2001","journal-title":"American journal of respiratory and critical care medicine"},{"key":"ref50","unstructured":"World Health Organization. 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