{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T05:54:26Z","timestamp":1793253266180,"version":"4.5.0"},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2017,1,19]],"date-time":"2017-01-19T00:00:00Z","timestamp":1484784000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0170277","type":"journal-article","created":{"date-parts":[[2017,1,19]],"date-time":"2017-01-19T14:41:23Z","timestamp":1484836883000},"page":"e0170277","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":23,"title":["Comparison of the Effect of Two Kinds of Iranian Honey and Diphenhydramine on Nocturnal Cough and the Sleep Quality in Coughing Children and Their Parents"],"prefix":"10.1371","volume":"12","author":[{"given":"Parviz","family":"Ayazi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abolfazl","family":"Mahyar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahdieh","family":"Yousef-Zanjani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Allami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neda","family":"Esmailzadehha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taraneh","family":"Beyhaghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,1,19]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"S64","DOI":"10.1016\/j.prrv.2006.04.172","article-title":"Acute and chronic cough","volume":"7","author":"LI Landau","year":"2006","journal-title":"Paediatr Respir Rev"},{"key":"ref2","first-page":"1434","article-title":"Nelson Text Book of Pediatrics","author":"RB Turner","year":"2015"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1136\/adc.79.3.225","article-title":"Systematic review of the treatment of upper respiratory tract infection","volume":"79","author":"T Fahey","year":"1998","journal-title":"Arch Dis Child"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1542\/peds.2011-3075","article-title":"Effect of Honey on Nocturnal Cough and Sleep Quality: A Double-blind, Randomized, Placebo-Controlled Study","volume":"130","author":"HA Cohen","year":"2012","journal-title":"Pediatrics"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.annemergmed.2008.09.015","article-title":"Pediatric fatalities associated with over the counter (nonprescription) cough and cold medications","volume":"53","author":"RC Dart","year":"2009","journal-title":"Ann Emerg Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1542\/peds.99.6.918","article-title":"Use of codeine- and dextromethorphan containing cough remedies in children","volume":"99","year":"1997","journal-title":"Pediatrics"},{"key":"ref7","unstructured":"Food and Drug Administration. FDA releases recommendations regarding use of over the- counter cough and cold products. 2008. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.fda.gov\/bbs\/topics\/NEWS\/2008\/NEW01778\" xlink:type=\"simple\">http:\/\/www.fda.gov\/bbs\/topics\/NEWS\/2008\/NEW01778<\/ext-link>."},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1001\/archpedi.161.12.1149","article-title":"The effect of honey on nocturnal cough and sleep quality for children and their parents","volume":"161","author":"MD Warren","year":"2007","journal-title":"Arch Pediatr Adolesc Med"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1177\/0009922806291014","article-title":"Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection","volume":"45","author":"KE Yoder","year":"2006","journal-title":"Clin Pediatr (Phila)"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1001\/archpedi.161.12.1140","article-title":"Effect of honey dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents","volume":"161","author":"IM Paul","year":"2007","journal-title":"Arch Pediatr Adolesc Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"e85","DOI":"10.1542\/peds.114.1.e85","article-title":"Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents","volume":"114","author":"IM Paul","year":"2004","journal-title":"Pediatrics"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1542\/pir.26-5-170","article-title":"A multicultural approach to the patient who has a common cold","volume":"26","author":"WF Pfeiffer","year":"2005","journal-title":"Pediatr Rev"},{"key":"ref13","article-title":"Cough and cold remedies for the treatment of acute respiratory infections in young children","year":"2001"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.arcmed.2005.03.038","article-title":"Bactericidal activity of different honeys against pathogenic bacteria","volume":"36","author":"PE Lusby","year":"2005","journal-title":"Arch Med Res"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S1043-4666(03)00092-9","article-title":"Honey stimulates inflammatory cytokine production from monocytes","volume":"21","author":"AJ Tonks","year":"2003","journal-title":"Cytokine"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1089\/acm.2009.0311","article-title":"A comparison of the effect of honey, dextromethorphan, and diphenhydramine on nightly cough and sleep quality in children and their parents","volume":"16","author":"MN Shadkam","year":"2010","journal-title":"J Altern Complement Med"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1016\/j.rmed.2005.09.039","article-title":"Non-antibiotic treatments for upper-respiratory tract infections (common cold)","volume":"99","author":"B Arroll","year":"2005","journal-title":"Respir Med"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s11096-007-9122-2","article-title":"Efficacy of diphenhydramine against cough in humans: A review","volume":"29","author":"I Bjornsdottir","year":"2007","journal-title":"Pharm World Sci"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"e318","DOI":"10.1542\/peds.2007-3813","article-title":"Unexpected infant deaths associated with use of cough and cold medications","volume":"122","author":"ME Rimsza","year":"2008","journal-title":"Pediatrics"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1191\/096032700671040438","article-title":"Dose-dependent toxicity of diphenhydramine overdose","volume":"19","author":"D Radovanovic","year":"2000","journal-title":"Hum ExpToxicol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/S1081-1206(10)61950-3","article-title":"Increased risk of serious injury following an initial prescription for diphenhydramine","volume":"89","author":"WD Finkle","year":"2002","journal-title":"Ann Allergy Asthma Immunol"},{"key":"ref22","first-page":"136","article-title":"Diphenhydramine dependence: A need for awareness","volume":"57","author":"AP De Nesnera","year":"1996","journal-title":"J Clin Psychiatry"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/0735-6757(86)90312-8","article-title":"Diphenhydramine-induced toxic psychosis","volume":"4","author":"J Jones","year":"1986","journal-title":"Am J Emerg Med"},{"issue":"12","key":"ref24","first-page":"CD007094","article-title":"Honey for acute cough in children","author":"O Oduwole","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s00408-011-9319-y","article-title":"Therapeutic Options for Acute Cough Due to Upper Respiratory Infections in Children","volume":"190","author":"IM Paul","year":"2012","journal-title":"Lung"},{"key":"ref26","first-page":"157","article-title":"Honey: A Comprehensive Survey","author":"JW White","year":"1975"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1002\/jsfa.1823","article-title":"Carbohydrate composition and physico chemical properties of artisanal honeys from Madrid (Spain): occurrence of Echium sp. honey","volume":"84","author":"ML Sanz","year":"2004","journal-title":"J Sci Food Agric"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.foodchem.2006.07.053","article-title":"Trace element levels in honeys from different regions of Turkey","volume":"103","author":"M Tuzen","year":"2007","journal-title":"Food Chem"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0163-7258(02)00298-X","article-title":"The biochemistry and medical significance of the flavonoids","volume":"96","author":"BH Havsteen","year":"2002","journal-title":"Pharmacol Ther"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1021\/jf025897t","article-title":"Buckwheat honey increases serum antioxidant capacity in humans","volume":"51","author":"N Gheldof","year":"2003","journal-title":"J Agric Food Chem"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1089\/acm.2007.6366","article-title":"Bactericidal activity of different types of honey against clinical and environmental isolates of Pseudomonas aeruginosa","volume":"13","author":"V Mullai","year":"2007","journal-title":"J Altern Complement Med"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.resp.2005.10.004","article-title":"Mechanisms of the placebo effect of sweet cough syrups","volume":"152","author":"R Eccles","year":"2006","journal-title":"Respir Physiol Neurobiol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0168-1605(01)00615-8","article-title":"High prevalence of Clostridium botulinum types A and B in honey samples detected by polymerase chain reaction","volume":"72","author":"M Nevas","year":"2002","journal-title":"Int J Food Microbiol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0170277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T18:41:09Z","timestamp":1588963269000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0170277"}},"subtitle":[],"editor":[{"given":"Thomas","family":"Penzel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,1,19]]},"references-count":33,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,1,19]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0170277","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,19]]}}}