{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T11:22:10Z","timestamp":1777029730962,"version":"3.51.4"},"reference-count":30,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2017,1,25]],"date-time":"2017-01-25T00:00:00Z","timestamp":1485302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0170319","type":"journal-article","created":{"date-parts":[[2017,1,25]],"date-time":"2017-01-25T14:37:06Z","timestamp":1485355026000},"page":"e0170319","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":16,"title":["Rectal Culture-Guided Targeted Antimicrobial Prophylaxis Reduces the Incidence of Post-Operative Infectious Complications in Men at High Risk for Infections Submitted to Transrectal Ultrasound Prostate Biopsy \u2013 Results of a Cross-Sectional Study"],"prefix":"10.1371","volume":"12","author":[{"given":"Luca","family":"Boeri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Fontana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Gallioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano Paolo","family":"Zanetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Catellani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Longo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Mangiarotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Montanari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2017,1,25]]},"reference":[{"key":"ref1","first-page":"124","article-title":"EAU guidelines on prostate cancer. part 1: screening, diagnosis, and local treatment with curative intent-update 2013. European Association of Urology","volume":"65","author":"A Heidenreich","year":"2014"},{"key":"ref2","first-page":"1830","article-title":"Complications after prostate biopsy: data from SEER-Medicare","volume":"186","author":"S Loeb","year":"2011"},{"key":"ref3","first-page":"963","article-title":"Increasing hospital admission rates for urological complications after transrectal ultrasound guided prostate biopsy","volume":"183","author":"RK Nam","year":"2010"},{"key":"ref4","first-page":"267","article-title":"Infectious complications following transrectal-ultrasound (TRUS) guided prostate biopsy: new challenges in the era of multi-drug resistant Escherichia coli","volume":"52","author":"DA Williamson","year":"2013"},{"key":"ref5","first-page":"733","article-title":"Prophylactic Antibiotics in Prostate Biopsy: A Meta-Analysis Based on Randomized Controlled Trials","volume":"16","author":"L Yang","year":"2015"},{"key":"ref6","first-page":"453","article-title":"Increasing risk of infectious complications after transrectal ultrasound-guided prostate biopsies: time to reassess antimicrobial prophylaxis?","volume":"62","author":"A Carignan","year":"2012"},{"key":"ref7","first-page":"1035","article-title":"Emergence of fluoroquinolone-resistant Escherichia coli as cause of postprostate biopsy infection: implications for prophylaxis and treatment","volume":"77","author":"OM Zaytoun","year":"2011"},{"key":"ref8","first-page":"301","article-title":"Baseline prevalence of antimicrobial resistance and subsequent infection following prostate biopsy using empirical or altered prophylaxis: A bias-adjusted meta-analysis","volume":"43","author":"MJ Roberts","year":"2014"},{"key":"ref9","first-page":"1673","article-title":"Fluoroquinolone resistant rectal colonization predicts risk of infectious complications after transrectal prostate biopsy","volume":"192","author":"MA Liss","year":"2014"},{"key":"ref10","unstructured":"Liss MA, Ehdaie B, Loeb S, Meng MV, Raman JD, Spears V et al. AUA White Paper on The prevention and treatment of the more common complications related to prostate biopsy update. 2016. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.auanet.org\/common\/pdf\/education\/clinical-guidance\/AUA-PNB-White-Paper.pdf\" xlink:type=\"simple\">https:\/\/www.auanet.org\/common\/pdf\/education\/clinical-guidance\/AUA-PNB-White-Paper.pdf<\/ext-link>"},{"key":"ref11","first-page":"E86","article-title":"Cost-effectiveness of standard vs intensive antibiotic regimens for transrectal ultrasonography (TRUS)-guided prostate biopsy prophylaxis","volume":"110","author":"M Adibi","year":"2012"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.urology.2008.01.065","article-title":"Multi-drug-resistant bacteremia after transrectal ultrasound guided prostate biopsies in hospital employees and their relatives","volume":"72","author":"C Kamdar","year":"2008","journal-title":"Urology"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1111\/j.1464-410X.2011.10561.x","article-title":"Infection after transrectal ultrasonography-guided prostate biopsy: increased relative risks after recent international travel or antibiotic use","volume":"109","author":"U Patel","year":"2012","journal-title":"BJU Int"},{"key":"ref14","first-page":"867","article-title":"Is repeat prostate biopsy associated with a greater risk of hospitalization? Data from SEER-Medicare","volume":"189","author":"S Loeb","year":"2013"},{"key":"ref15","first-page":"521","article-title":"Infective complications after prostate biopsy: outcome of the Global Prevalence Study of Infections in Urology (GPIU) 2010 and 2011, a prospective multinational multicentre prostate biopsy study","volume":"63","author":"FM Wagenlehner","year":"2013"},{"key":"ref16","first-page":"1283","article-title":"Prevalence and significance of fluoroquinolone resistant Escherichia coli in patients undergoing transrectal ultrasound guided prostate needle biopsy","volume":"185","author":"MA Liss","year":"2011"},{"key":"ref17","first-page":"365","article-title":"Rectal swab testing before prostate biopsy: experience in a VA Medical Center urology practice","volume":"18","author":"I Cook","year":"2015"},{"key":"ref18","first-page":"1275","article-title":"Targeted antimicrobial prophylaxis using rectal swab cultures in men undergoing transrectal ultrasound guided prostate biopsy is associated with reduced incidence of postoperative infectious complications and cost of care","volume":"187","author":"AK Taylor","year":"2012"},{"key":"ref19","first-page":"725","article-title":"The role of targeted prophylactic antimicrobial therapy before transrectal ultrasonography-guided prostatebiopsy in reducing infection rates: a systematic review","volume":"117","author":"A Cussans","year":"2016"},{"key":"ref20","first-page":"373","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"ME Charlson","year":"1987"},{"key":"ref21","unstructured":"European Association of Urology Guidelines on Urological Infections. 2014. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/uroweb.org\/guideline\/urological-infections\/\" xlink:type=\"simple\">https:\/\/uroweb.org\/guideline\/urological-infections\/<\/ext-link>"},{"key":"ref22","first-page":"556","article-title":"Rectal cultures before transrectal ultrasound-guided prostate biopsy reduce post-prostatic biopsy infection rates","volume":"79","author":"CA Duplessis","year":"2012"},{"key":"ref23","first-page":"8","article-title":"Rectal swab culture-directed antimicrobial prophylaxis for prostate biopsy and risk of postprocedure infection: a cohort study","volume":"85","author":"J Dai","year":"2015"},{"key":"ref24","first-page":"2001","article-title":"An antimicrobial prophylaxis protocol using rectal swab cultures for transrectal prostate biopsy","volume":"33","author":"SJ Summers","year":"2015"},{"key":"ref25","first-page":"973","article-title":"Modification of antimicrobial prophylaxis based on rectal culture results to prevent fluoroquinolone-resistant Escherichia coli infections after prostate biopsy","volume":"34","author":"N Suwantarat","year":"2013"},{"key":"ref26","first-page":"353","article-title":"Modeling antibiotic resistance to project future rates: quinolone resistance in Escherichia coli","volume":"29","author":"LK Durham","year":"2010"},{"key":"ref27","first-page":"7","article-title":"Cost-effectiveness of culture-guided antimicrobial prophylaxis for the prevention of infections after prostatebiopsy","volume":"43","author":"CK Li","year":"2016"},{"key":"ref28","first-page":"131","article-title":"Prevalence of ciprofloxacin-resistant Enterobacteriaceae in the intestinal flora of patients undergoing transrectal prostate biopsy in Norwich, UK","volume":"116","author":"MY Hanna","year":"2015"},{"key":"ref29","first-page":"5392107","article-title":"Prevalence, Risk Factors, and Clinical Relevance of Fluoroquinolone-Resistant Organisms in Rectal Cultures: Should We Target Antibiotic Prophylaxis Prior to Prostate Biopsy?","volume":"2016","author":"J Van Besien","year":"2016"},{"key":"ref30","first-page":"280","article-title":"The prevalence of fluoroquinolone resistance mechanisms in colonizing Escherichia coli isolates recovered from hospitalized patients","volume":"51","author":"E Lautenbach","year":"2010"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0170319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T16:15:41Z","timestamp":1540311341000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0170319"}},"subtitle":[],"editor":[{"given":"Peter C","family":"Black","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2017,1,25]]},"references-count":30,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,1,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0170319","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,25]]}}}