{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:06:14Z","timestamp":1773281174583,"version":"3.50.1"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T00:00:00Z","timestamp":1486684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"China Academy of Chinese Medical Sciences and Peking Union Medical College (CN)","award":["201510020101"],"award-info":[{"award-number":["201510020101"]}]},{"name":"National Health and Family Planning Commission of the People's Republic of China (CN)","award":["201502019"],"award-info":[{"award-number":["201502019"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0171869","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T13:55:18Z","timestamp":1486734918000},"page":"e0171869","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of different inspiratory triggering settings in automated ventilators during cardiopulmonary resuscitation in a porcine model"],"prefix":"10.1371","volume":"12","author":[{"given":"Dingyu","family":"Tan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shihuan","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangyang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yazhi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingying","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Walline","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huadong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuezhong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2017,2,10]]},"reference":[{"issue":"16","key":"ref1","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1161\/01.CIR.0000126594.79136.61","article-title":"Hyperventilation-induced hypotension during cardiopulmonary resuscitation","volume":"109","author":"TP Aufderheide","year":"2004","journal-title":"Circulation"},{"issue":"9 Suppl","key":"ref2","doi-asserted-by":"crossref","first-page":"S345","DOI":"10.1097\/01.CCM.0000134335.46859.09","article-title":"Death by hyperventilation: a common and life-threatening problem during cardiopulmonary resuscitation","volume":"32","author":"TP Aufderheide","year":"2004","journal-title":"Crit Care Med"},{"issue":"4","key":"ref3","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1097\/00003246-199804000-00020","article-title":"Increasing tidal volumes and pulmonary overdistention adversely affect pulmonary vascular mechanics and cardiac output in a pediatric swine model","volume":"26","author":"IM Cheifetz","year":"1998","journal-title":"Crit Care Med"},{"issue":"1","key":"ref4","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.resuscitation.2006.09.012","article-title":"Do we hyperventilate cardiac arrest patients?","volume":"73","author":"JF O'Neill","year":"2007","journal-title":"Resuscitation"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1001\/jama.293.3.305","article-title":"Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest","volume":"293","author":"BS Abella","year":"2005","journal-title":"JAMA"},{"issue":"8","key":"ref6","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.resuscitation.2011.03.020","article-title":"The first quantitative report of ventilation rate during in-hospital resuscitation of older children and adolescents","volume":"82","author":"AD McInnes","year":"2011","journal-title":"Resuscitation"},{"issue":"8","key":"ref7","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1111\/j.1553-2712.1995.tb03624.x","article-title":"Out-of-hospital ventilation: bag\u2014valve device vs transport ventilator","volume":"2","author":"JA Johannigman","year":"1995","journal-title":"Acad Emerg Med"},{"issue":"1","key":"ref8","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.resuscitation.2006.01.023","article-title":"Comparison of ventilation and cardiac compressions using the Impact Model 730 automatic transport ventilator compared to a conventional bag valve with a facemask in a model of adult cardiopulmonary arrest","volume":"74","author":"N Salas","year":"2007","journal-title":"Resuscitation"},{"issue":"18","key":"ref9","doi-asserted-by":"crossref","first-page":"S444","DOI":"10.1161\/CIR.0000000000000261","article-title":"Part 7: Adult Advanced Cardiovascular Life Support: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care","volume":"132","author":"MS Link","year":"2015","journal-title":"Circulation"},{"issue":"10","key":"ref10","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1097\/01.smj.0000182177.01436.70","article-title":"Automatic transport ventilator versus bag valve in the EMS setting: a prospective, randomized trial","volume":"98","author":"SJ Weiss","year":"2005","journal-title":"South Med J"},{"issue":"1","key":"ref11","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.resuscitation.2006.07.027","article-title":"Comparison of ventilation and chest compression performance by bystanders using the Impact Model 730 ventilator and a conventional bag valve with mask in a model of adult cardiopulmonary arrest","volume":"73","author":"Hurst Vt","year":"2007","journal-title":"Resuscitation"},{"issue":"2","key":"ref12","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/BF01726540","article-title":"Characteristics of the ventilator pressure- and flow-trigger variables","volume":"21","author":"CS Sassoon","year":"1995","journal-title":"Intensive Care Med"},{"issue":"18","key":"ref13","doi-asserted-by":"crossref","first-page":"S414","DOI":"10.1161\/CIR.0000000000000259","article-title":"Part 5: Adult Basic Life Support and Cardiopulmonary Resuscitation Quality: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care","volume":"132","author":"ME Kleinman","year":"2015","journal-title":"Circulation"},{"issue":"9431","key":"ref14","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0140-6736(04)16740-8","article-title":"Hyperventilation during cardiac arrest","volume":"364","author":"S Pitts","year":"2004","journal-title":"Lancet"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.resuscitation.2012.07.028","article-title":"A clinical observational study analysing the factors associated with hyperventilation during actual cardiopulmonary resuscitation in the emergency department","volume":"84","author":"SO Park","year":"2013","journal-title":"Resuscitation"},{"key":"ref16","article-title":"Mitigating hyperventilation during cardiopulmonary resuscitation","author":"D Nikolla","year":"2015","journal-title":"Am J Emerg Med"},{"issue":"18","key":"ref17","doi-asserted-by":"crossref","first-page":"S436","DOI":"10.1161\/CIR.0000000000000260","article-title":"Part 6: Alternative Techniques and Ancillary Devices for Cardiopulmonary Resuscitation: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care","volume":"132","author":"SC Brooks","year":"2015","journal-title":"Circulation"},{"issue":"9","key":"ref18","first-page":"1056","article-title":"Mechanical ventilator design and function: the trigger variable","volume":"37","author":"CS Sassoon","year":"1992","journal-title":"Respir Care"},{"issue":"12","key":"ref19","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1111\/j.1651-2227.1998.tb00948.x","article-title":"Comparison of airway pressure-triggered and airflow-triggered ventilation in very immature infants","volume":"87","author":"G Dimitriou","year":"1998","journal-title":"Acta Paediatr"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.resuscitation.2011.07.034","article-title":"Clinically plausible hyperventilation does not exert adverse hemodynamic effects during CPR but markedly reduces end-tidal PCO(2)","volume":"83","author":"RJ Gazmuri","year":"2012","journal-title":"Resuscitation"},{"issue":"1","key":"ref21","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1177\/2048872613516923","article-title":"Timing positive-pressure ventilation during chest compression: the key to improving the thoracic pump?","volume":"4","author":"A Chalkias","year":"2015","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.resuscitation.2016.10.023","article-title":"Airway pressure and outcome of out-of-hospital cardiac arrest: A prospective observational study","volume":"110","author":"A Chalkias","year":"2017","journal-title":"Resuscitation"},{"issue":"5","key":"ref23","doi-asserted-by":"crossref","first-page":"e0127759","DOI":"10.1371\/journal.pone.0127759","article-title":"Chest Compression Synchronized Ventilation versus Intermitted Positive Pressure Ventilation during Cardiopulmonary Resuscitation in a Pig Model","volume":"10","author":"C Kill","year":"2015","journal-title":"PLoS One"},{"issue":"9752","key":"ref24","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1016\/S0140-6736(10)61454-7","article-title":"Chest-compression-only versus standard cardiopulmonary resuscitation: a meta-analysis","volume":"376","author":"M Hupfl","year":"2010","journal-title":"Lancet"},{"issue":"6","key":"ref25","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1007\/s00134-006-0137-2","article-title":"Constant flow insufflation of oxygen as the sole mode of ventilation during out-of-hospital cardiac arrest","volume":"32","author":"C Bertrand","year":"2006","journal-title":"Intensive Care Med"},{"issue":"3","key":"ref26","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1161\/01.CIR.0000021428.94652.04","article-title":"Decompression-triggered positive-pressure ventilation during cardiopulmonary resuscitation improves pulmonary gas exchange and oxygen uptake","volume":"106","author":"A Kleinsasser","year":"2002","journal-title":"Circulation"},{"issue":"2","key":"ref27","doi-asserted-by":"crossref","first-page":"e89","DOI":"10.1097\/CCM.0b013e3182a63fa0","article-title":"Mechanical ventilation during cardiopulmonary resuscitation with intermittent positive-pressure ventilation, bilevel ventilation, or chest compression synchronized ventilation in a pig model","volume":"42","author":"C Kill","year":"2014","journal-title":"Crit Care Med"},{"issue":"7","key":"ref28","first-page":"862","article-title":"Comparison of a 10-breaths-per-minute versus a 2-breaths-per-minute strategy during cardiopulmonary resuscitation in a porcine model of cardiac arrest","volume":"53","author":"KG Lurie","year":"2008","journal-title":"Respir Care"},{"issue":"1","key":"ref29","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.resuscitation.2008.04.015","article-title":"Impact of different compression-ventilation ratios during basic life support cardiopulmonary resuscitation","volume":"79","author":"E Cavus","year":"2008","journal-title":"Resuscitation"},{"issue":"11","key":"ref30","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1097\/00003246-199422110-00019","article-title":"Effect of ventilation on acid-base balance and oxygenation in low blood-flow states","volume":"22","author":"AH Idris","year":"1994","journal-title":"Crit Care Med"},{"issue":"5","key":"ref31","first-page":"284","article-title":"Echocardiography integrated ACLS protocol versus conventional cardiopulmonary resuscitation in patients with pulseless electrical activity cardiac arrest","volume":"15","author":"M Chardoli","year":"2012","journal-title":"Chin J Traumatol"},{"issue":"10","key":"ref32","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1016\/S0196-0644(05)81512-4","article-title":"Relationship between cardiac output and the end-tidal carbon dioxide tension","volume":"19","author":"JP Ornato","year":"1990","journal-title":"Ann Emerg Med"},{"issue":"9","key":"ref33","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/S0196-0644(05)80650-X","article-title":"The clinical implications of continuous central venous oxygen saturation during human CPR","volume":"21","author":"EP Rivers","year":"1992","journal-title":"Ann Emerg Med"},{"issue":"7","key":"ref34","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/EJA.0000000000000064","article-title":"Central venous-to-arterial carbon dioxide partial pressure difference in early resuscitation from septic shock: a prospective observational study","volume":"31","author":"J Mallat","year":"2014","journal-title":"Eur J Anaesthesiol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0171869","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T09:36:38Z","timestamp":1540028198000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0171869"}},"subtitle":[],"editor":[{"given":"Chiara","family":"Lazzeri","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2017,2,10]]},"references-count":34,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,2,10]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0171869","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,10]]}}}