{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T01:18:15Z","timestamp":1760404695624,"version":"3.37.3"},"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T00:00:00Z","timestamp":1487635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Mato Grosso do Sul (FUNDECT)","award":["FUNDECT\/CAPES n\u00b0 45\/2014 - PAPOS REDE PR\u00d3-CENTRO-OESTE FASE II - N\u00ba 23\/200.622\/2014"],"award-info":[{"award-number":["FUNDECT\/CAPES n\u00b0 45\/2014 - PAPOS REDE PR\u00d3-CENTRO-OESTE FASE II - N\u00ba 23\/200.622\/2014"]}]},{"name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico (CNPq)"},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["scholarships"],"award-info":[{"award-number":["scholarships"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["scholarships"],"award-info":[{"award-number":["scholarships"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0172151","type":"journal-article","created":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T14:23:37Z","timestamp":1487687017000},"page":"e0172151","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":18,"title":["Antidepressive and antinociceptive effects of ethanolic extract and fruticuline A from Salvia lachnostachys Benth leaves on rodents"],"prefix":"10.1371","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6969-0087","authenticated-orcid":true,"given":"Joyce Alencar","family":"Santos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Claudia","family":"Piccinelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maira Dante","family":"Formagio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristhian Santos","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elide Pereira dos","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria \u00c9lida","family":"Alves Stefanello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ubirajara","family":"Lanza Junior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo Juliano","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rio Mateus","family":"Sugizaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e2ndida Aparecida Leite","family":"Kassuya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2017,2,21]]},"reference":[{"issue":"2","key":"ref1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/aob\/mcl176","article-title":"Staminal evolution in the genus <italic>Salvia<\/italic> (Lamiaceae): molecular phylogenetic evidence for multiple origins of the staminal lever","volume":"100","author":"JB Walker","year":"2007","journal-title":"Annuals of Botany"},{"issue":"5","key":"ref2","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1111\/j.1476-5381.2009.00230.x","article-title":"Potential anxiolytic\u2010and antidepressant\u2010like effects of salvinorin A, the main active ingredient of <italic>Salvia divinorum<\/italic>, in rodents","volume":"157","author":"D Braida","year":"2009","journal-title":"Br J Pharmacol"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"13260","DOI":"10.3390\/molecules181113260","article-title":"Isosakuranetin-5-O-rutinoside: a new flavanone with antidepressant activity isolated from <italic>Salvia elegans<\/italic> Vahl","volume":"18","author":"M Gonz\u00e1lez-Cortazar","year":"2013","journal-title":"Molecules"},{"issue":"2","key":"ref4","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.jep.2011.11.042","article-title":"Antinociceptive and anti-inflammatory potential of extract and isolated compounds from the leaves of <italic>Salvia officinalis<\/italic> in mice","volume":"139","author":"MRA Rodrigues","year":"2012","journal-title":"J Ethnopharmacol"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.jep.2009.08.031","article-title":"Anti-inflammatory, anti-angiogenic and anti-nociceptive activities of an ethanol extract of <italic>Salvia plebeia<\/italic> R. Brown","volume":"126","author":"H-J Jung","year":"2009","journal-title":"J Ethnopharmacol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"835914","DOI":"10.1155\/2014\/835914","article-title":"Anti-Inflammatory and Antihyperalgesic Activities of Ethanolic Extract and fruticuline A from <italic>Salvia lachnostachys<\/italic> Leaves in Mice","volume":"2014","author":"AC Piccinelli","year":"2014","journal-title":"Evid Based Complement Alternat Med"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.phytol.2016.07.005","article-title":"Cytotoxic abietane-derivative diterpenoids of <italic>Salvia lachnostachys<\/italic>","volume":"17","author":"CS Oliveira","year":"2016","journal-title":"Phytochem Lett"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"5291","DOI":"10.2741\/3598","article-title":"Neurobiology of depression, fibromyalgia and neuropathic pain","volume":"14","author":"VMCL Raison","year":"2009","journal-title":"Front Biosci"},{"key":"ref9","first-page":"15","article-title":"Translational investigation and treatment of neuropathic pain","volume":"8","author":"B Xu","year":"2012","journal-title":"Mol Pain"},{"issue":"8","key":"ref10","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S1474-4422(10)70143-5","article-title":"Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment","volume":"9","author":"R Baron","year":"2010","journal-title":"Lancet Neurol"},{"key":"ref11","first-page":"7","article-title":"TNF-\u03b1 and neuropathic pain-a review","author":"L Leung","year":"2010","journal-title":"J Neuroinflammation"},{"issue":"2","key":"ref12","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0304-3959(00)00276-1","article-title":"Spared nerve injury: an animal model of persistent peripheral neuropathic pain","volume":"87","author":"I Decosterd","year":"2000","journal-title":"Pain"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"539","DOI":"10.2147\/JPR.S45966","article-title":"Systematic review and comparison of pharmacologic therapies for neuropathic pain associated with spinal cord injury","volume":"6","author":"SJ Snedecor","year":"2013","journal-title":"J pain res"},{"issue":"12","key":"ref14","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1002\/jemt.22125","article-title":"Morphoanatomical and phytochemical studies of <italic>Salvia lachnostachys<\/italic> (Lamiaceae)","volume":"75","author":"M Erbano","year":"2012","journal-title":"Microsc Res Tech"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"10468","DOI":"10.1021\/jf802200x","article-title":"Antimicrobial activity of the ornamental species <italic>Salvia corrugata<\/italic>, a potential new crop for extractive purposes","volume":"56","author":"A Bisio","year":"2008","journal-title":"J Agric Food Chem"},{"issue":"1\u20132","key":"ref16","first-page":"14","article-title":"Assessment and analysis of mechanical allodynia-like behavior induced by spared nerve injury (SNI) in the mouse","volume":"122","author":"AF Bourquin","year":"2006","journal-title":"Pain"},{"issue":"4","key":"ref17","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0168-0102(01)00289-9","article-title":"Central and peripheral roles of prostaglandins in pain and their interactions with novel neuropeptides nociceptin and nocistatin","volume":"41","author":"S Ito","year":"2001","journal-title":"Neurosci Res"},{"issue":"2","key":"ref18","first-page":"327","article-title":"Behavioral despair in mice: a primary screening test for antidepressants","volume":"229","author":"RD Porsolt","year":"1977","journal-title":"Arch int pharmacodyn ther"},{"issue":"3","key":"ref19","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.jep.2009.06.003","article-title":"Antipyretic and anti-inflammatory properties of the ethanolic extract, dichloromethane fraction and costunolide from <italic>Magnolia ovata<\/italic> (Magnoliaceae)","volume":"124","author":"CA Kassuya","year":"2009","journal-title":"J Ethnopharmacol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.5897\/AJPP2013.3928","article-title":"Role of serotonergic and dopaminergic neurotransmission in the antidepressant effects of malt extract","author":"HF Zaki","year":"2013","journal-title":"African J Pharmacy Pharmacol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.neuropharm.2015.06.003","article-title":"Enhanced serotonin and mesolimbic dopamine transmissions in a rat model of neuropathic pain","volume":"97","author":"C Sagheddu","year":"2015","journal-title":"Neuropharmacology"},{"issue":"4","key":"ref22","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1097\/ALN.0b013e31822f16ae","article-title":"A Single Sub-anesthetic Dose of Ketamine Relieves Depression-like Behaviors Induced by Neuropathic Pain in Rats","volume":"115","author":"J Wang","year":"2011","journal-title":"Anesthesiology"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"159015","DOI":"10.1155\/2015\/159015","article-title":"Subchronic Arsenic Exposure Induces Anxiety-Like Behaviors in Normal Mice and Enhances Depression-Like Behaviors in the Chemically Induced Mouse Model of Depression","volume":"2015","author":"CY Chang","year":"2015","journal-title":"Biomed Res Int"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.brainresbull.2013.10.007","article-title":"Substance P receptor antagonist in lateral habenula improves rat depression-like behaviors","volume":"100","author":"L-M Yang","year":"2013","journal-title":"Brain Research Bulletin"},{"issue":"12","key":"ref25","first-page":"3","article-title":"Pina. <italic>Hypericum<\/italic> for Depression","volume":"2","author":"PL Bongiorno","year":"2010","journal-title":"Natural Med J"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/978-1-60327-323-7_4","article-title":"Animal models of acute and chronic inflammatory and nociceptive pain","volume":"617","author":"JM Boyce-Rustay","year":"2010","journal-title":"Methods Mol Biol"},{"issue":"2","key":"ref27","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1097\/00000542-199808000-00034","article-title":"Intravenous regional clonidine in the management of sympathetically maintained pain","volume":"89","author":"SS Reuben","year":"1998","journal-title":"Anesthesiology"},{"issue":"1","key":"ref28","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.pbb.2006.07.030","article-title":"Antidepressant-like effect of lectin from <italic>Canavalia brasiliensis<\/italic> (ConBr) administered centrally in mice","volume":"85","author":"SC Barauna","year":"2006","journal-title":"Pharmacol Biochem Behav"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.pbb.2014.01.006","article-title":"Potential antioxidant and anxiolytic effects of (+)-limonene epoxide in mice after marble-burying test","volume":"118","author":"AA de Almeida","year":"2014","journal-title":"Pharmacol Biochem Behav"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.pbb.2014.05.015","article-title":"Serotonergic and noradrenergic systems are implicated in the antidepressant-like effect of ursolic acid in mice","volume":"124","author":"AR Colla","year":"2014","journal-title":"Pharmacol Biochem Behav"},{"issue":"1","key":"ref31","first-page":"34","article-title":"Tolerance to the antinociceptive effects of chronic morphine requires c-Jun N-terminal kinase","volume":"11","author":"DJ Marcus","year":"2015","journal-title":"Mol Pain"},{"issue":"1","key":"ref32","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0304-3959(87)90088-1","article-title":"The formalin test in mice: dissociation between inflammatory and non-inflammatory pain","volume":"30","author":"S Hunskaar","year":"1987","journal-title":"Pain"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0172151","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T00:01:02Z","timestamp":1540339262000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0172151"}},"subtitle":[],"editor":[{"given":"Claudia","family":"Sommer","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2017,2,21]]},"references-count":32,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,2,21]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0172151","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2017,2,21]]}}}