{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T09:52:12Z","timestamp":1783763532125,"version":"3.55.0"},"reference-count":23,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T00:00:00Z","timestamp":1487203200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2011-2891"],"award-info":[{"award-number":["2011-2891"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","award":["2010\/1171 and2014\/575"],"award-info":[{"award-number":["2010\/1171 and2014\/575"]}],"id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","award":["9807"],"award-info":[{"award-number":["9807"]}],"id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002706","name":"AFA F\u00f6rs\u00e4kring","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002706","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004200","name":"Stiftelsen Olle Engkvist Byggm\u00e4stare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001858","name":"VINNOVA","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008550","name":"Diabetesfonden","doi-asserted-by":"publisher","award":["DIA2015-035"],"award-info":[{"award-number":["DIA2015-035"]}],"id":[{"id":"10.13039\/501100008550","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003173","name":"Crafoordska Stiftelsen","doi-asserted-by":"publisher","award":["20160579"],"award-info":[{"award-number":["20160579"]}],"id":[{"id":"10.13039\/501100003173","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0172445","type":"journal-article","created":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T21:39:17Z","timestamp":1487281157000},"page":"e0172445","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":19,"title":["Thermal stability and structural changes in bacterial toxins responsible for food poisoning"],"prefix":"10.1371","volume":"12","author":[{"given":"Paulina","family":"Regenthal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesper S.","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingemar","family":"Andr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5209-3160","authenticated-orcid":true,"given":"Karin","family":"Lindkvist-Petersson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,2,16]]},"reference":[{"issue":"8","key":"ref1","doi-asserted-by":"crossref","first-page":"759","DOI":"10.4161\/viru.23905","article-title":"The staphylococcal enterotoxin (SE) family: SEB and siblings","volume":"4","author":"T Krakauer","year":"2013","journal-title":"Virulence"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.0300-9475.2004.01404.x","article-title":"Interplay between superantigens and immunoreceptors","volume":"59","author":"K Petersson","year":"2004","journal-title":"Scandinavian journal of immunology"},{"issue":"7","key":"ref3","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.3390\/toxins2071751","article-title":"Food poisoning and Staphylococcus aureus enterotoxins","volume":"2","author":"MA Argudin","year":"2010","journal-title":"Toxins (Basel)"},{"issue":"5","key":"ref4","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1128\/AEM.30.5.755-758.1975","article-title":"Influence of pH on the heat inactivation of staphylococcal enterotoxin A as determined by monkey feeding and serological assay","volume":"30","author":"JY Humber","year":"1975","journal-title":"Appl Microbiol"},{"issue":"8","key":"ref5","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.3390\/toxins2082177","article-title":"Staphylococcal enterotoxins","volume":"2","author":"IV Pinchuk","year":"2010","journal-title":"Toxins (Basel)"},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1128\/AEM.71.5.2793-2795.2005","article-title":"Mass outbreak of food poisoning disease caused by small amounts of staphylococcal enterotoxins A and H","volume":"71","author":"T Ikeda","year":"2005","journal-title":"Appl Environ Microbiol"},{"issue":"2","key":"ref7","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.femsle.2005.09.005","article-title":"An outbreak of staphylococcal food poisoning caused by enterotoxin H in mashed potato made with raw milk","volume":"252","author":"HJ Jorgensen","year":"2005","journal-title":"FEMS Microbiol Lett"},{"issue":"1","key":"ref8","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/j.foodres.2013.03.002","article-title":"Enterotoxinomics: The omic sciences in the study of staphylococcal toxins analyzed in food matrices","volume":"54","author":"I Sospedra","year":"2013","journal-title":"Food Res Int"},{"issue":"4","key":"ref9","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.jmb.2007.01.024","article-title":"Crystal structure of the streptococcal superantigen SpeI and functional role of a novel loop domain in T cell activation by group V superantigens","volume":"367","author":"JN Brouillard","year":"2007","journal-title":"Journal of molecular biology"},{"issue":"12","key":"ref10","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1016\/S0969-2126(02)00895-X","article-title":"Crystal structure of a SEA variant in complex with MHC class II reveals the ability of SEA to crosslink MHC molecules","volume":"10","author":"K Petersson","year":"2002","journal-title":"Structure"},{"issue":"13","key":"ref11","doi-asserted-by":"crossref","first-page":"3306","DOI":"10.1093\/emboj\/20.13.3306","article-title":"Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence","volume":"20","author":"K Petersson","year":"2001","journal-title":"The EMBO journal"},{"issue":"22","key":"ref12","doi-asserted-by":"crossref","first-page":"4673","DOI":"10.1093\/nar\/22.22.4673","article-title":"CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice","volume":"22","author":"JD Thompson","year":"1994","journal-title":"Nucleic Acids Res"},{"issue":"3","key":"ref13","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1074\/jbc.275.3.1665","article-title":"The spectral and thermodynamic properties of staphylococcal enterotoxin A, E, and variants suggest that structural modifications are important to control their function","volume":"275","author":"A Cavallin","year":"2000","journal-title":"The Journal of biological chemistry"},{"issue":"12","key":"ref14","doi-asserted-by":"crossref","first-page":"6686","DOI":"10.4049\/jimmunol.163.12.6686","article-title":"Staphylococcal enterotoxin H displays unique MHC class II-binding properties","volume":"163","author":"H Nilsson","year":"1999","journal-title":"J Immunol"},{"issue":"7","key":"ref15","doi-asserted-by":"crossref","first-page":"e0131988","DOI":"10.1371\/journal.pone.0131988","article-title":"Structure of Staphylococcal Enterotoxin E in Complex with TCR Defines the Role of TCR Loop Positioning in Superantigen Recognition","volume":"10","author":"KE Rodstrom","year":"2015","journal-title":"PloS one"},{"issue":"24","key":"ref16","doi-asserted-by":"crossref","first-page":"E3095","DOI":"10.1073\/pnas.1500851112","article-title":"Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy","volume":"112","author":"A Micsonai","year":"2015","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"7","key":"ref17","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH Image to ImageJ: 25 years of image analysis","volume":"9","author":"CA Schneider","year":"2012","journal-title":"Nature methods"},{"issue":"3","key":"ref18","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1006\/jmbi.2000.4093","article-title":"The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules","volume":"302","author":"M Hakansson","year":"2000","journal-title":"Journal of molecular biology"},{"issue":"14","key":"ref19","doi-asserted-by":"crossref","first-page":"3292","DOI":"10.1002\/j.1460-2075.1995.tb07336.x","article-title":"Crystal structure of the superantigen staphylococcal enterotoxin type A","volume":"14","author":"EM Schad","year":"1995","journal-title":"The EMBO journal"},{"issue":"6398","key":"ref20","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/359801a0","article-title":"Crystal structure of staphylococcal enterotoxin B, a superantigen","volume":"359","author":"S Swaminathan","year":"1992","journal-title":"Nature"},{"issue":"3","key":"ref21","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1016\/S0006-3495(01)75824-9","article-title":"Decomposition of protein tryptophan fluorescence spectra into log-normal components. II. The statistical proof of discreteness of tryptophan classes in proteins","volume":"81","author":"YK Reshetnyak","year":"2001","journal-title":"Biophysical journal"},{"issue":"6","key":"ref22","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1016\/j.bbapap.2010.01.014","article-title":"Staphylococcal enterotoxin A: Partial unfolding caused by high pressure or denaturing agents enhances superantigenicity","volume":"1804","author":"M Rene-Trouillefou","year":"2010","journal-title":"Biochimica et biophysica acta"},{"issue":"2","key":"ref23","doi-asserted-by":"crossref","first-page":"e14674","DOI":"10.1371\/journal.pone.0014674","article-title":"Structure and stability of the spinach aquaporin SoPIP2;1 in detergent micelles and lipid membranes","volume":"6","author":"I Plasencia","year":"2011","journal-title":"PloS one"}],"updated-by":[{"DOI":"10.1371\/journal.pone.0175989","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2017,4,12]],"date-time":"2017-04-12T00:00:00Z","timestamp":1491955200000}}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0172445","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T07:41:20Z","timestamp":1692690080000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0172445"}},"subtitle":[],"editor":[{"given":"Eugene A.","family":"Permyakov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,2,16]]},"references-count":23,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,2,16]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0172445","relation":{"correction":[{"id-type":"doi","id":"10.1371\/journal.pone.0175989","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,16]]}}}