{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:44:44Z","timestamp":1790729084354,"version":"4.1.0"},"reference-count":24,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2017,5,4]],"date-time":"2017-05-04T00:00:00Z","timestamp":1493856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000226","name":"Ontario Ministry of Health and Long-Term Care","doi-asserted-by":"publisher","award":["CHA-12-003"],"award-info":[{"award-number":["CHA-12-003"]}],"id":[{"id":"10.13039\/501100000226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0175922","type":"journal-article","created":{"date-parts":[[2017,5,4]],"date-time":"2017-05-04T17:31:51Z","timestamp":1493919111000},"page":"e0175922","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":18,"title":["Poractant alfa versus bovine lipid extract surfactant for infants 24+0 to 31+6 weeks gestational age: A randomized controlled trial"],"prefix":"10.1371","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2743-0417","authenticated-orcid":true,"given":"Brigitte","family":"Lemyre","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Fusch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg M.","family":"Schm\u00f6lzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Rouvinez Bouali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepti","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Barrowman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Huneault-Purney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Lacaze-Masmonteil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,5,4]]},"reference":[{"issue":"2","key":"ref1","first-page":"CD007836","article-title":"Animal derived surfactant extract for treatment of respiratory distress syndrome","author":"N Seger","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"ref2","first-page":"CD000510","article-title":"Prophylactic versus selective use of surfactant in preventing morbidity and mortality in preterm infants","author":"MX Rojas-Reyes","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"ref3","first-page":"CD001079","article-title":"Prophylactic protein free synthetic surfactant for preventing morbidity and mortality in preterm infants","author":"R Soll","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"ref4","first-page":"CD000511","article-title":"Prophylactic natural surfactant extract for preventing morbidity and mortality in preterm infants","author":"RF Soll","year":"2000","journal-title":"Cochrane Database Syst Rev"},{"issue":"Suppl 1","key":"ref5","doi-asserted-by":"publisher","first-page":"S47","DOI":"10.1038\/jp.2008.50","article-title":"Surfactants: past, present and future","volume":"28","author":"HL Halliday","year":"2008","journal-title":"J Perinatol"},{"issue":"1","key":"ref6","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1002\/ppul.20125","article-title":"Randomized trial comparing two natural surfactants (Survanta vs. bLES) for treatment of neonatal respiratory distress syndrome","volume":"39","author":"BC Lam","year":"2005","journal-title":"Pediatr Pulmonol"},{"key":"ref7","article-title":"Severe airway obstruction during surfactant administration using a standardized protocol: a prospective, observational study","author":"A Tarawneh","year":"2011","journal-title":"J Perinatol"},{"issue":"Suppl 2","key":"ref8","doi-asserted-by":"publisher","first-page":"S38","DOI":"10.1038\/jp.2009.31","article-title":"Animal-derived surfactants: where are we? The evidence from randomized, controlled clinical trials","volume":"29","author":"R Ramanathan","year":"2009","journal-title":"J Perinatol"},{"issue":"3","key":"ref9","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1055\/s-2004-823779","article-title":"A randomized, multicenter masked comparison trial of poractant alfa (Curosurf) versus beractant (Survanta) in the treatment of respiratory distress syndrome in preterm infants","volume":"21","author":"R Ramanathan","year":"2004","journal-title":"Am J Perinatol"},{"issue":"6","key":"ref10","doi-asserted-by":"publisher","first-page":"e1588","DOI":"10.1542\/peds.2011-1395","article-title":"Efficacy of Porcine Versus Bovine Surfactants for Preterm Newborns With Respiratory Distress Syndrome: Systematic Review and Meta-analysis","volume":"128","author":"N Singh","year":"2011","journal-title":"Pediatrics"},{"issue":"6","key":"ref11","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1177\/000992287000900607","article-title":"Respiratory distress syndrome of newborn infants. I. New clinical scoring system (RDS score) with acid\u2014base and blood-gas correlations","volume":"9","author":"JJ Downes","year":"1970","journal-title":"Clin Pediatr (Phila)"},{"issue":"7","key":"ref12","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.1164\/ajrccm.163.7.2011060","article-title":"Bronchopulmonary dysplasia","volume":"163","author":"AH Jobe","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"ref13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00000658-197801000-00001","article-title":"Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging","volume":"187","author":"MJ Bell","year":"1978","journal-title":"Ann Surg"},{"issue":"4","key":"ref14","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","article-title":"Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm","volume":"92","author":"LA Papile","year":"1978","journal-title":"J Pediatr"},{"issue":"1","key":"ref15","doi-asserted-by":"publisher","first-page":"F8","DOI":"10.1136\/fn.72.1.F8","article-title":"Randomised clinical trial of two treatment regimens of natural surfactant preparations in neonatal respiratory distress syndrome","volume":"72","author":"CP Speer","year":"1995","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"7\u20138","key":"ref16","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1007\/s00431-002-1144-0","article-title":"Comparison of three treatment regimens of natural surfactant preparations in neonatal respiratory distress syndrome","volume":"162","author":"G Baroutis","year":"2003","journal-title":"Eur J Pediatr"},{"issue":"10","key":"ref17","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1038\/jp.2010.20","article-title":"Poractant alfa and beractant treatment of very premature infants with respiratory distress syndrome","volume":"30","author":"AM Fujii","year":"2010","journal-title":"J Perinatol"},{"issue":"4","key":"ref18","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1542\/peds.2004-2231","article-title":"A multicenter, randomized, controlled trial of lucinactant versus poractant alfa among very premature infants at high risk for respiratory distress syndrome","volume":"115","author":"SK Sinha","year":"2005","journal-title":"Pediatrics"},{"issue":"9213","key":"ref19","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1016\/S0140-6736(00)02136-X","article-title":"Pumactant and poractant alfa for treatment of respiratory distress syndrome in neonates born at 25\u201329 weeks&apos; gestation: a randomised trial","volume":"355","author":"SB Ainsworth","year":"2000","journal-title":"Lancet"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1542\/peds.76.2.145","article-title":"Prevention of neonatal respiratory distress syndrome by tracheal instillation of surfactant: a randomized clinical trial","volume":"76","author":"G Enhorning","year":"1985","journal-title":"Pediatrics"},{"issue":"3","key":"ref21","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1542\/peds.87.3.377","article-title":"Bovine surfactant replacement therapy in neonates of less than 30 weeks&apos; gestation: a randomized controlled trial of prophylaxis versus treatment","volume":"87","author":"MS Dunn","year":"1991","journal-title":"Pediatrics"},{"issue":"4","key":"ref22","article-title":"A Randomized, blinded, Canadian multi-center trial, to compare a bovine surfactant, bLES (R) (b), with a synthetic Exosurf (E) for the rescue treatment of RDS in premature newborns &lt; or = 1250g","volume":"43","author":"A Peliowski","year":"1998","journal-title":"Pediatr Research"},{"issue":"5","key":"ref23","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1007\/s00134-002-1277-7","article-title":"Sequential changes in compliance and resistance after bolus administration or slow infusion of surfactant in preterm infants","volume":"28","author":"R Hentschel","year":"2002","journal-title":"Intensive Care Med"},{"issue":"4","key":"ref24","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1203\/00006450-199310000-00021","article-title":"Pulmonary distribution and efficacy of exogenous surfactant in lung-lavaged rabbits are influenced by the instillation technique","volume":"34","author":"H Segerer","year":"1993","journal-title":"Pediatr Res"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0175922","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T06:43:38Z","timestamp":1658990618000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0175922"}},"subtitle":[],"editor":[{"given":"Olivier","family":"Baud","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,5,4]]},"references-count":24,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2017,5,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0175922","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,4]]}}}