{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T13:39:49Z","timestamp":1773927589268,"version":"3.50.1"},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T00:00:00Z","timestamp":1493164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0176552","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T17:46:26Z","timestamp":1493228786000},"page":"e0176552","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":32,"title":["Restless legs syndrome and cardiovascular diseases: A case-control study"],"prefix":"10.1371","volume":"12","author":[{"given":"Marion","family":"Cholley-Roulleau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofiene","family":"Chenini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9verine","family":"B\u00e9ziat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lily","family":"Guiraud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Jaussent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Dauvilliers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2017,4,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/S1389-9457(03)00010-8","article-title":"Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health","volume":"4","author":"RP Allen","year":"2003","journal-title":"Sleep Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1016\/j.sleep.2014.03.025","article-title":"Restless legs syndrome\/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria\u2014history, rationale, description, and significance","volume":"15","author":"RP Allen","year":"2014","journal-title":"Sleep Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1002\/mds.25860","article-title":"Prospective study of obesity, hypertension, high cholesterol, and risk of restless legs syndrome","volume":"29","author":"K De Vito","year":"2014","journal-title":"Mov Disord"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1212\/01.wnl.0000345673.35676.1c","article-title":"Obesity and restless legs syndrome in men and women","volume":"72","author":"X Gao","year":"2009","journal-title":"Neurology"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.smrv.2014.03.003","article-title":"Hypertension and sleep: overview of a tight relationship","volume":"18","author":"JL Pepin","year":"2014","journal-title":"Sleep Med Rev"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1002\/mds.22486","article-title":"Cardiovascular risk factors in restless legs syndrome","volume":"24","author":"I Schlesinger","year":"2009","journal-title":"Mov Disord"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1002\/mds.870120111","article-title":"Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: a study of 133 patients diagnosed with new standard criteria","volume":"12","author":"J Montplaisir","year":"1997","journal-title":"Mov Disord"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1212\/01.wnl.0000259036.89411.52","article-title":"Nocturnal blood pressure changes in patients with restless legs syndrome","volume":"68","author":"MH Pennestri","year":"2007","journal-title":"Neurology"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1002\/ana.24593","article-title":"Prevalence and determinants of periodic limb movements in the general population","volume":"79","author":"J Haba-Rubio","year":"2016","journal-title":"Ann Neurol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1161\/CIRCULATIONAHA.111.038968","article-title":"Association of incident cardiovascular disease with periodic limb movements during sleep in older men: outcomes of sleep disorders in older men (MrOS) study","volume":"124","author":"BB Koo","year":"2011","journal-title":"Circulation"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1097\/MCP.0b013e328365ab07","article-title":"Restless legs syndrome: update on pathogenesis","volume":"19","author":"Y Dauvilliers","year":"2013","journal-title":"Curr Opin Pulm Med"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1161\/HYPERTENSIONAHA.111.174037","article-title":"Restless legs syndrome and hypertension in middle-aged women","volume":"58","author":"S Batool-Anwar","year":"2011","journal-title":"Hypertension"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1689","DOI":"10.1161\/CIRCULATIONAHA.112.112698","article-title":"Prospective study of restless legs syndrome and coronary heart disease among women","volume":"126","author":"Y Li","year":"2012","journal-title":"Circulation"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.sleep.2009.04.009","article-title":"Differential diagnosis of unpleasant sensations in the legs: prevalence of restless legs syndrome in a primary care population","volume":"11","author":"C Moller","year":"2010","journal-title":"Sleep Med"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/S0022-3999(02)00443-9","article-title":"Prevalence of restless legs syndrome and periodic limb movement disorder in the general population","volume":"53","author":"MM Ohayon","year":"2002","journal-title":"J Psychosom Res"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1111\/jsr.12040","article-title":"A time sequence analysis of the relationship between cardiovascular risk factors, vascular diseases and restless legs syndrome in the general population","volume":"22","author":"A Szentkiralyi","year":"2013","journal-title":"J Sleep Res"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2012-001652","article-title":"Restless legs syndrome and all-cause mortality in four prospective cohort studies","volume":"2","author":"A Szentkiralyi","year":"2012","journal-title":"BMJ Open"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.5665\/sleep.4800","article-title":"Risk of Cardiovascular Disease Associated with a Restless Legs Syndrome Diagnosis in a Retrospective Cohort Study from Kaiser Permanente Northern California","volume":"38","author":"SK Van Den Eeden","year":"2015","journal-title":"Sleep"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1212\/01.wnl.0000287072.93277.c9","article-title":"Association of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study","volume":"70","author":"JW Winkelman","year":"2008","journal-title":"Neurology"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"e000866","DOI":"10.1136\/bmjopen-2012-000866","article-title":"Restless legs syndrome and risk of incident cardiovascular disease in women and men: prospective cohort study","volume":"2","author":"AC Winter","year":"2012","journal-title":"BMJ Open"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.amjmed.2012.06.040","article-title":"Vascular risk factors, cardiovascular disease, and restless legs syndrome in women","volume":"126","author":"AC Winter","year":"2013","journal-title":"Am J Med"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"119","DOI":"10.5664\/jcsm.1756","article-title":"Incidence of restless legs syndrome and its correlates","volume":"8","author":"P Budhiraja","year":"2012","journal-title":"J Clin Sleep Med"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1212\/WNL.0000000000002542","article-title":"Restless legs syndrome associated with major diseases: A systematic review and new concept","volume":"86","author":"C Trenkwalder","year":"2016","journal-title":"Neurology"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1161\/STROKEAHA.108.530824","article-title":"Excessive daytime sleepiness is an independent risk indicator for cardiovascular mortality in community-dwelling elderly: the three city study","volume":"40","author":"JP Empana","year":"2009","journal-title":"Stroke"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"e56048","DOI":"10.1371\/journal.pone.0056048","article-title":"Insomnia, daytime sleepiness and cardio-cerebrovascular diseases in the elderly: a 6-year prospective study","volume":"8","author":"I Jaussent","year":"2013","journal-title":"PLoS One"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"2073","DOI":"10.1161\/CIRCULATIONAHA.111.025858","article-title":"Insomnia and the risk of acute myocardial infarction: a population study","volume":"124","author":"LE Laugsand","year":"2011","journal-title":"Circulation"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/S1389-9457(02)00258-7","article-title":"Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome","volume":"4","author":"AS Walters","year":"2003","journal-title":"Sleep Med"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1111\/j.1524-4733.2005.03010.x","article-title":"Validation of the Restless Legs Syndrome Quality of Life questionnaire","volume":"8","author":"L Abetz","year":"2005","journal-title":"Value Health"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1016\/j.sleep.2007.03.022","article-title":"Diagnostic standards for dopaminergic augmentation of restless legs syndrome: report from a World Association of Sleep Medicine-International Restless Legs Syndrome Study Group consensus conference at the Max Planck Institute","volume":"8","author":"D Garcia-Borreguero","year":"2007","journal-title":"Sleep Med"},{"key":"ref30","unstructured":"Beck AT, Steer RA, Brown GK (1996) Inventaire de d\u00e9pression de Beck- deuxi\u00e8me \u00e9dition."},{"key":"ref31","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","article-title":"A new method for measuring daytime sleepiness: the Epworth sleepiness scale","volume":"14","author":"MW Johns","year":"1991","journal-title":"Sleep"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S1389-9457(00)00065-4","article-title":"Validation of the Insomnia Severity Index as an outcome measure for insomnia research","volume":"2","author":"CH Bastien","year":"2001","journal-title":"Sleep Med"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.1212\/WNL.0000000000002649","article-title":"Rotigotine's effect on PLM-associated blood pressure elevations in restless legs syndrome: An RCT","volume":"86","author":"A Bauer","year":"2016","journal-title":"Neurology"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.11627","article-title":"Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death","volume":"5","author":"F Bouilloux","year":"2016","journal-title":"Elife"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"e1002171","DOI":"10.1371\/journal.pgen.1002171","article-title":"Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1","volume":"7","author":"J Winkelmann","year":"2011","journal-title":"PLoS Genet"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.smrv.2011.04.001","article-title":"Restless legs syndrome and conditions associated with metabolic dysregulation, sympathoadrenal dysfunction, and cardiovascular disease risk: a systematic review","volume":"16","author":"KE Innes","year":"2012","journal-title":"Sleep Med Rev"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0176552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T09:53:46Z","timestamp":1601978026000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0176552"}},"subtitle":[],"editor":[{"given":"Raffaele","family":"Ferri","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2017,4,26]]},"references-count":36,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2017,4,26]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0176552","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,26]]}}}