{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T23:04:38Z","timestamp":1793055878166,"version":"4.5.0"},"reference-count":47,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2017,5,4]],"date-time":"2017-05-04T00:00:00Z","timestamp":1493856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Science Concil","award":["(NSC)-NSC99-2627-B-038-001"],"award-info":[{"award-number":["(NSC)-NSC99-2627-B-038-001"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0176849","type":"journal-article","created":{"date-parts":[[2017,5,4]],"date-time":"2017-05-04T18:10:45Z","timestamp":1493921445000},"page":"e0176849","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":143,"title":["Efficacy of cognitive-behavioral therapy in patients with bipolar disorder: A meta-analysis of randomized controlled trials"],"prefix":"10.1371","volume":"12","author":[{"given":"Kai-Jo","family":"Chiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jui-Chen","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doresses","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chueh-Ho","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huei-Ling","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4882-3503","authenticated-orcid":true,"given":"Kuei-Ru","family":"Chou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,5,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/BF00805795","article-title":"The epidemiology of bipolar affective disorder","volume":"30","author":"P Bebbington","year":"1995","journal-title":"Soc Psychiatry Psychiatr Epidemiol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e12","DOI":"10.4088\/JCP.1006e12","article-title":"Cognitive impairment and functional outcome in schizophrenia and bipolar disorder","volume":"67","author":"MF Green","year":"2006","journal-title":"J Clin Psychiatry"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1159\/000228249","article-title":"Functioning and disability in bipolar disorder: an extensive review","volume":"78","author":"J Sanchez-Moreno","year":"2009","journal-title":"Psychother Psychosom"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1001\/jamapsychiatry.2013.1394","article-title":"Comorbidities and mortality in bipolar disorder: a Swedish national cohort study","volume":"70","author":"C Crump","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1111\/bdi.12087","article-title":"Epidemiology of suicide in bipolar disorders:a systematic review of the literature","volume":"15","author":"M Pompili","year":"2013","journal-title":"Bipolar Disord"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1176\/appi.ajp.163.2.217","article-title":"Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)","volume":"163","author":"RH Perlis","year":"2006","journal-title":"Am J Psychiatry"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.jad.2010.08.030","article-title":"An estimate of the minimum economic burden of bipolar I and II disorders in the United States: 2009","volume":"129","author":"SC Dilsaver","year":"2011","journal-title":"J Affect Disord"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1016\/S0140-6736(15)60692-4","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronicdiseases and injuries in 188 countries, 1990\u20132013: a systematic analysis for the Global Burden of Disease Study 2013","volume":"386","year":"2015","journal-title":"Lancet"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1007\/s11920-006-0057-4","article-title":"An update on the role of psychotherapy in the management of bipolar disorder","volume":"8","author":"DJ Miklowitz","year":"2006","journal-title":"Curr Psychiatry Rep"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1192\/bjp.bp.107.037887","article-title":"Psychosocial interventions for the prevention of relapse in bipolar disorder: systematic review of controlled trials","volume":"192","author":"S Beynon","year":"2008","journal-title":"Br J Psychiatry"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"418","DOI":"10.4088\/JCP.v69n0312","article-title":"Predictors and time course of response among panic disorder patients treated with cognitive-behavioral therapy","volume":"69","author":"CJ Aaronson","year":"2008","journal-title":"J Clin Psychiatry"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.12740\/PP\/24992","article-title":"Group psychoeducation in bipolar mood disorders\u2013the influence on the cognitive representation of the illness. The results of the program:\u201cTaming the bipolar affective disorder\u201d","volume":"48","author":"G Ma\u02dbczka","year":"2014","journal-title":"Psychiatr. Pol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1176\/appi.ajp.2008.08040488","article-title":"Adjunctive psychotherapy for bipolar disorder: state of the evidence","volume":"165","author":"DJ Miklowitz","year":"2008","journal-title":"Am J Psychiatry"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1002\/wps.20149","article-title":"The promise of cognitive behavior therapy for treatment of severe mental disorders: a review of recent developments","volume":"13","author":"ME Thase","year":"2014","journal-title":"World Psychiatry"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.4088\/JCP.v69n1102","article-title":"Are psychological and pharmacologic interventions equally effective in the treatment of adult depressive disorders? A meta-analysis of comparative studies","volume":"69","author":"P Cuijpers","year":"2008","journal-title":"J Clin Psychiatry"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"621","DOI":"10.4088\/JCP.v69n0415","article-title":"Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebocontrolled trials","volume":"69","author":"SG Hofmann","year":"2008","journal-title":"J Clin Psychiatry"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"66","DOI":"10.4088\/JCP.08r04559yel","article-title":"The efficacy of cognitive-behavioral therapy in bipolar disorder: a quantitative meta-analysis","volume":"71","author":"A Szentagotai","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1080\/15433710903176088","article-title":"Cognitive-behavioral therapy for depression in bipolar disorder: a meta-analysis","volume":"7","author":"VL Gregory Jr","year":"2010","journal-title":"J Evid Based Soc Work"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1111\/pcn.12399","article-title":"Effectiveness of Cognitive Behavioral Therapy in Treating Bipolar Disorder: An Updated Meta-analysis with Randomized Controlled Trials","volume":"70","author":"BY Ye","year":"2016","journal-title":"Psychiatry Clin Neurosci"},{"issue":"1","key":"ref20","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1017\/S1461145706006900","article-title":"A meta-analysis of relapse rates with adjunctive psychological therapies compared to usual psychiatric treatment for bipolar disorders","volume":"10","author":"J Scott","year":"2007","journal-title":"International Journal of Neuropsychopharmacology"},{"issue":"5","key":"ref21","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1111\/j.1399-5618.2009.00724.x","article-title":"Psychological therapies in bipolar disorder: the effect of illness history on relapse prevention\u2014a systematic review","volume":"11","author":"DH Lam","year":"2009","journal-title":"Bipolar Disord"},{"issue":"1","key":"ref22","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1017\/S003329170900590X","article-title":"Cognitive behavioural therapy for major psychiatric disorder: Does it really work? A meta-analytical review of well-controlled trials","volume":"40","author":"D Lynch","year":"2010","journal-title":"Psychological Medicine"},{"issue":"3","key":"ref23","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1192\/bjp.bp.114.157123","article-title":"Psychological interventions for adults with bipolar disorder: systematic review and meta-analysis","volume":"208","author":"M Oud","year":"2016","journal-title":"The British journal of psychiatry: the journal of mental science"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1002\/9780470712184","article-title":"Cochrane Handbook for Systematic Reviews of Interventions","author":"JP Higgins","year":"2008"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1023\/A:1005557911051","article-title":"Cognitive therapy for bipolar illness\u2014a pilot study of relapse prevention","volume":"24","author":"DH Lam","year":"2000","journal-title":"Cognitive Therapy and Research"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1017\/S0033291701003373","article-title":"A pilot study of cognitive therapy in bipolar disorders","volume":"31","author":"J Scott","year":"2001","journal-title":"Psychol Med"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1001\/archpsyc.60.2.145","article-title":"A randomized controlled study of cognitive therapy for relapse prevention for bipolar affective disorder: outcome of the first year","volume":"60","author":"DH Lam","year":"2003","journal-title":"Arch Gen Psychiatry"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"277","DOI":"10.4088\/JCP.v67n0215","article-title":"A randomized controlled trial of cognitive therapy for bipolar disorder: focus on long-term change","volume":"67","author":"JR Ball","year":"2006","journal-title":"J Clin Psychiatry"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1192\/bjp.188.4.313","article-title":"Cognitive-behavioural therapy for severe and recurrent bipolar disorders: randomised controlled trial","volume":"188","author":"J Scott","year":"2006","journal-title":"Br J Psychiatry"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.1176\/appi.ajp.2007.07020311","article-title":"Intensive psychosocial intervention enhances functioning in patients with bipolar depression: results from a 9-month randomized controlled trial","volume":"164","author":"DJ Miklowitz","year":"2007","journal-title":"Am J Psychiatry"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.jad.2007.08.022","article-title":"Mindfulness-based Cognitive Therapy (MBCT) in bipolar disorder: preliminary evaluation of immediate effects on between-episode functioning","volume":"107","author":"JM Williams","year":"2008","journal-title":"J Affect Disord"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1177\/070674370805300709","article-title":"Is cognitive-behavioural therapy more effective than psychoeducation in bipolar disorder?","volume":"53","author":"A Zaretsky","year":"2008","journal-title":"Can J Psychiatry"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1111\/j.1399-5618.2010.00852.x","article-title":"Family-focused treatment for caregivers of patients with bipolar disorder","volume":"12","author":"DA Perlick","year":"2010","journal-title":"Bipolar Disord"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1590\/S1516-44462011000200009","article-title":"The effectiveness of cognitive behavioral group therapy in treating bipolar disorder: a randomized controlled study","volume":"33","author":"RT Costa","year":"2011","journal-title":"Rev Bras Psiquiatr"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1159\/000320738","article-title":"A randomized controlled trial of cognitive behavioral group therapy for bipolar disorder","volume":"80","author":"BC Gomes","year":"2011","journal-title":"Psychother Psychosom"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1017\/S0033291711002522","article-title":"Cognitive behaviour therapy and supportive therapy for bipolar disorders: relapse rates for treatment period and 2-year follow-up","volume":"42","author":"TD Meyer","year":"2012","journal-title":"Psychol Med"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1037\/a0038655","article-title":"Treating insomnia improves mood state, sleep, and functioning in bipolar disorder: a pilot randomized controlled trial","volume":"83","author":"AG Harvey","year":"2015","journal-title":"J Consult Clin Psychol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1001\/archpsyc.60.4.402","article-title":"A randomized trial on the efficacy of group psychoeducation in the prophylaxis of recurrences in bipolar patients whose disease is in remission","volume":"60","author":"F Colom","year":"2003","journal-title":"Arch Gen Psychiatry"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.jad.2010.03.026","article-title":"How effective is a psychological intervention program for patients with refractory bipolar disorder? A randomized controlled trial","volume":"126","author":"A Gonz\u00e1lez-Isasi","year":"2010","journal-title":"J Affect Disord"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1176\/ajp.2007.164.1.100","article-title":"A randomized trial of integrated group therapy versus group drug counseling for patients with bipolar disorder and substance dependence","volume":"164","author":"RD Weiss","year":"2007","journal-title":"Am J Psychiatry"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.drugalcdep.2009.04.018","article-title":"A &quot;community-friendly&quot; version of integrated group therapy for patients with bipolar disorder and substance dependence: a randomized controlled trial","volume":"104","author":"RD Weiss","year":"2009","journal-title":"Drug Alcohol Depend"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1111\/acps.12033","article-title":"A randomized controlled trial of mindfulness-based cognitive therapy for bipolar disorder","volume":"127","author":"T Perich","year":"2013","journal-title":"Acta Psychiatr Scand"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.psychres.2008.06.047","article-title":"Long-term efficacy of a psychological intervention program for patients with refractory bipolar disorder: a pilot study","volume":"176","author":"A Gonz\u00e1lez-Isasi","year":"2010","journal-title":"Psychiatry Res"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1034\/j.1600-0579.2003.00210.x","article-title":"Meta-analysis of psychosocial interventions for caregivers of patients with dementia","volume":"51","author":"H Brodaty","year":"2003","journal-title":"J Am Geriatr Soc"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1017\/S0033291704002910","article-title":"Sense of hyper-positive self and response to cognitive therapy in bipolar disorder","volume":"35","author":"D Lam","year":"2005","journal-title":"Psychol Med"},{"key":"ref46","article-title":"Methods of Meta-Analysis: Correcting Error and Bias in Research Findings","author":"JE Hunter","year":"1990"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/2047-2501-2-3","article-title":"Big data analytics in healthcare: promise and potential","volume":"2","author":"W Raghupathi","year":"2014","journal-title":"Health Inf Sci Syst"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0176849","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T05:58:04Z","timestamp":1589003884000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0176849"}},"subtitle":[],"editor":[{"given":"Marianna","family":"Mazza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,5,4]]},"references-count":47,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2017,5,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0176849","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,4]]}}}