{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T22:40:36Z","timestamp":1783118436962,"version":"3.54.6"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2017,5,10]],"date-time":"2017-05-10T00:00:00Z","timestamp":1494374400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["FIS PI16\/00072"],"award-info":[{"award-number":["FIS PI16\/00072"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003030","name":"Ag\u00e8ncia de Gesti\u00f3 d\u2019Ajuts Universitaris i de Recerca","doi-asserted-by":"publisher","award":["2014SGR804"],"award-info":[{"award-number":["2014SGR804"]}],"id":[{"id":"10.13039\/501100003030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["RD16\/0009"],"award-info":[{"award-number":["RD16\/0009"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008050","name":"Fundaci\u00f3n Cellex","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003030","name":"Ag\u00e8ncia de Gesti\u00f3 d\u2019Ajuts Universitaris i de Recerca","doi-asserted-by":"publisher","award":["2014BP B00118"],"award-info":[{"award-number":["2014BP B00118"]}],"id":[{"id":"10.13039\/501100003030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["SNS- ISCIII"],"award-info":[{"award-number":["SNS- ISCIII"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["CES07\/015"],"award-info":[{"award-number":["CES07\/015"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0176987","type":"journal-article","created":{"date-parts":[[2017,5,10]],"date-time":"2017-05-10T18:27:06Z","timestamp":1494440826000},"page":"e0176987","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":26,"title":["Characterization and proteomic profile of extracellular vesicles from peritoneal dialysis efflux"],"prefix":"10.1371","volume":"12","author":[{"given":"Laura","family":"Carreras-Planella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Soler-Majoral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Rubio-Esteve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara In\u00e9s","family":"Lozano-Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcella","family":"Franquesa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Bonet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Isabel","family":"Troya-Saborido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4038-1912","authenticated-orcid":true,"given":"Francesc Enric","family":"Borr\u00e0s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,5,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1177\/089686080802805S06","article-title":"Characterization of epithelial-to-mesenchymal transition of mesothelial cells in a mouse model of chronic peritoneal exposure to high glucose dialysate","volume":"28","author":"L Aroeira","year":"2008","journal-title":"Perit Dial"},{"issue":"5","key":"ref2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1056\/NEJMoa020809","article-title":"Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells","volume":"348","author":"M Y\u00e1\u00f1ez-Mo","year":"2003","journal-title":"N Engl J Med"},{"issue":"3","key":"ref3","first-page":"262","article-title":"Epithelial to mesenchymal transition as a triggering factor of peritoneal membrane fibrosis and angiogenesis in peritoneal dialysis patients","volume":"6","author":"A Aguilera","year":"2005","journal-title":"Curr Opin Investig Drugs"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s40258-014-0108-7","article-title":"Peritoneal dialysis and in-centre haemodialysis: A cost-utility analysis from a UK payer perspective","volume":"12","author":"C Treharne","year":"2014","journal-title":"Appl Health Econ Health Policy"},{"issue":"5","key":"ref5","doi-asserted-by":"crossref","first-page":"962","DOI":"10.4103\/1319-2442.164578","article-title":"Hemodialysis Versus Peritoneal Dialysis, Which is Cost-effective?","volume":"26","author":"A Atapour","year":"2015","journal-title":"Saudi J Kidney Dis Transpl"},{"issue":"11","key":"ref6","doi-asserted-by":"crossref","first-page":"4356","DOI":"10.1021\/pr0702969","article-title":"Proteomic Analysis of Peritoneal Dialysate Fluid in Patients with Different Types of Peritoneal Membranes\u2014Journal of Proteome Research (ACS Publications)","volume":"6","author":"S Sritippayawan","year":"2007","journal-title":"J Proteome Res"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1021\/pr9011574","article-title":"A proteomic view on the role of glucose in peritoneal dialysis","volume":"9","author":"M Lechner","year":"2010","journal-title":"J Proteome Res"},{"issue":"6","key":"ref8","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1093\/ndt\/gfp696","article-title":"Differential proteomic characterization between normal peritoneal fluid and diabetic peritoneal dialysate","volume":"25","author":"HY Wang","year":"2010","journal-title":"Nephrol Dial Transplant"},{"issue":"4","key":"ref9","doi-asserted-by":"crossref","first-page":"3886","DOI":"10.1021\/acsnano.5b08015","article-title":"Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine","volume":"10","author":"S Fais","year":"2016","journal-title":"ACS Nano"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"27066","DOI":"10.3402\/jev.v4.27066","article-title":"Biological properties of extracellular vesicles and their physiological functions","volume":"4","author":"M Y\u00e1\u00f1ez-M\u00f3","year":"2015","journal-title":"J Extracell vesicles"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.ceb.2009.03.007","article-title":"Exosomes\u2014vesicular carriers for intercellular communication","volume":"21","author":"M Simons","year":"2009","journal-title":"Curr Opin Cell Biol"},{"issue":"January","key":"ref12","first-page":"6","article-title":"Urinary Extracellular Vesicles as Source of Biomarkers in Kidney Diseases","volume":"6","author":"A G\u00e0mez-Valero","year":"2015","journal-title":"Front Immunol"},{"issue":"6803","key":"ref13","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1136\/bmj.303.6803.610","article-title":"Informed consent: study of quality of information given to participants in a clinical trial","volume":"303","author":"N Lyn\u00f6e","year":"1991","journal-title":"BMJ"},{"key":"ref14","first-page":"5","article-title":"Evaluation and Management of Ultrafiltration Residual Renal Therapy","volume":"20","author":"S Mujais","year":"2000","journal-title":"Society"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1159\/000170009","article-title":"Simple models for description of small-solute transport in peritoneal dialysis","volume":"9","author":"J Waniewski","year":"1991","journal-title":"Blood Purif"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"27369","DOI":"10.3402\/jev.v4.27369","article-title":"Size-exclusion chromatography-based enrichment of extracellular vesicles from urine samples","volume":"4","author":"I Lozano-Ramos","year":"2015","journal-title":"J Extracell vesicles"},{"issue":"12","key":"ref17","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1038\/nbt.1511","article-title":"MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification","volume":"26","author":"J Cox","year":"2008","journal-title":"Nat Biotechnol"},{"issue":"9","key":"ref18","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/nmeth.3901","article-title":"The Perseus computational platform for comprehensive analysis of (prote)omics data","volume":"13","author":"S Tyanova","year":"2016","journal-title":"Nat Methods"},{"issue":"1","key":"ref19","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/s12859-015-0611-3","article-title":"InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams","volume":"16","author":"H Heberle","year":"2015","journal-title":"BMC Bioinformatics"},{"issue":"6","key":"ref20","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1093\/bioinformatics\/btu741","article-title":"EVpedia: A community web portal for extracellular vesicles research","volume":"31","author":"DK Kim","year":"2015","journal-title":"Bioinformatics"},{"issue":"21","key":"ref21","doi-asserted-by":"crossref","first-page":"4997","DOI":"10.1002\/pmic.200900351","article-title":"ExoCarta: A compendium of exosomal proteins and RNA","volume":"9","author":"S Mathivanan","year":"2009","journal-title":"Proteomics"},{"issue":"12","key":"ref22","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1371\/journal.pbio.1001450","article-title":"Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation","volume":"10","author":"H Kalra","year":"2012","journal-title":"PLoS Biol"},{"issue":"3","key":"ref23","first-page":"1","article-title":"Relative survival of peritoneal dialysis and haemodialysis patients: Effect of cohort and mode of dialysis initiation","volume":"9","author":"JG Heaf","year":"2014","journal-title":"PLoS One"},{"issue":"8","key":"ref24","doi-asserted-by":"crossref","first-page":"619","DOI":"10.2215\/CJN.04810512","article-title":"Comparing mortality of peritoneal and hemodialysis patients in the first 2 years of dialysis therapy: a marginal structural model analysis","volume":"8","author":"LR Lukowsky","year":"2013","journal-title":"Clin J Am Soc Nephrol"},{"issue":"4","key":"ref25","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1053\/j.ajkd.2013.01.031","article-title":"Current status and practical use of effluent biomarkers in peritoneal dialysis patients","volume":"62","author":"D Lopes Barreto","year":"2013","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"ref26","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s12882-015-0039-z","article-title":"A microrna screen to identify regulators of peritoneal fibrosis in a rat model of peritoneal dialysis","volume":"16","author":"F Lin","year":"2015","journal-title":"BMC Nephrol"},{"key":"ref27","first-page":"1","article-title":"Extracellular Vesicles in Renal Diseases: More than Novel Biomarkers?","author":"U Erdbrugger","year":"2015","journal-title":"J Am Soc Nephrol"},{"issue":"3\u20134","key":"ref28","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/prca.201400114","article-title":"Exosomes in bodily fluids are a highly stable resource of disease biomarkers","volume":"9","author":"S Boukouris","year":"2015","journal-title":"Proteomics\u2014Clin Appl"},{"key":"ref29","article-title":"Size exclusion chromatography-based enrichment of extracelluar vesicles from urine samples","author":"I Lozano-Ramos","year":"2015","journal-title":"J Extracell Vesicles"},{"issue":"September","key":"ref30","doi-asserted-by":"crossref","first-page":"33641","DOI":"10.1038\/srep33641","article-title":"Size-Exclusion Chromatography-based isolation minimally alters Extracellular Vesicles\u2019 characteristics compared to precipitating agents","volume":"6","author":"A G\u00e1mez-Valero","year":"2016","journal-title":"Sci Rep"},{"issue":"January 2016","key":"ref31","article-title":"Applying extracellular vesicles based therapeutics in clinical trials\u2014an ISEV position paper","volume":"4","author":"T Lener","year":"2015","journal-title":"J Extracell Vesicles"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0176987","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,7]],"date-time":"2020-10-07T07:34:34Z","timestamp":1602056074000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0176987"}},"subtitle":[],"editor":[{"given":"Tatsuo","family":"Shimosawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,5,10]]},"references-count":31,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2017,5,10]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0176987","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,10]]}}}