{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:35:09Z","timestamp":1790469309032,"version":"4.1.0"},"reference-count":45,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T00:00:00Z","timestamp":1496102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0178488","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T13:44:31Z","timestamp":1496151871000},"page":"e0178488","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":59,"title":["Kidney volume measurement methods for clinical studies on autosomal dominant polycystic kidney disease"],"prefix":"10.1371","volume":"12","author":[{"given":"Kanishka","family":"Sharma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Caroli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le Van","family":"Quach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Petzold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michela","family":"Bozzetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas L.","family":"Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Remuzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Remuzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,5,30]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/S0272-6386(96)90378-9","article-title":"The etiology, pathogenesis, and treatment of autosomal dominant polycystic kidney disease: recent advances","volume":"28","author":"JJ Grantham","year":"1996","journal-title":"Am J Kidney Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.1056\/NEJMoa054341","article-title":"CRISP Investigators. Volume progression in polycystic kidney disease","volume":"354","author":"JJ Grantham","year":"2006","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"148","DOI":"10.2215\/CJN.00330705","article-title":"Volume progression in autosomal dominant polycystic kidney disease: the major factor determining clinical outcomes","volume":"1","author":"JJ Grantham","year":"2006","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"479","DOI":"10.2215\/CJN.09500911","article-title":"Kidney volume and functional outcomes in autosomal dominant polycystic kidney disease","volume":"7","author":"AB Chapman","year":"2012","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref5","first-page":"505","article-title":"Quantification and longitudinal trends of kidney, renal cyst, and renal parenchyma volumes in autosomal dominant polycystic kidney disease","volume":"11","author":"BF King","year":"2000","journal-title":"J Am Soc Nephrol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1046\/j.1523-1755.2000.00433.x","article-title":"Volumetric determination of progression in autosomal dominant polycystic kidney disease by computed tomography","volume":"58","author":"C Sise","year":"2000","journal-title":"Kidney Int"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/nrneph.2016.135","article-title":"The importance of total kidney volume in evaluating progression of polycystic kidney disease","volume":"12","author":"JJ Grantham","year":"2016","journal-title":"Nat Rev Nephrol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1056\/NEJMoa1205511","article-title":"Tolvaptan in patients with autosomal dominant polycystic kidney disease","volume":"367","author":"VE Torres","year":"2012","journal-title":"N Engl J Med"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/ki.2011.411","article-title":"Analysis of baseline parameters in the HALT polycystic kidney disease trials","volume":"81","author":"VE Torres","year":"2012","journal-title":"Kidney Int"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1056\/NEJMoa1003491","article-title":"Everolimus in patients with autosomal dominant polycystic kidney disease","volume":"363","author":"G Walz","year":"2010","journal-title":"N Engl J Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1056\/NEJMoa0907419","article-title":"Sirolimus and kidney growth in autosomal dominant polycystic kidney disease","volume":"363","author":"AL Serra","year":"2010","journal-title":"N Engl J Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/S0140-6736(13)61407-5","article-title":"Effect of longacting somatostatin analogue on kidney and cyst growth in autosomal dominant polycystic kidney disease (ALADIN): a randomised, placebo-controlled, multicentre trial: ALADIN study group","volume":"382","author":"A Caroli","year":"2013","journal-title":"Lancet"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"3560","DOI":"10.1093\/ndt\/gfs264","article-title":"Rapamycin for treatment of type I autosomal dominant polycystic kidney disease (RAPYD-study): a randomized, controlled study","volume":"27","author":"G Stallone","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1681\/ASN.2009121291","article-title":"Randomized clinical trial of long-acting somatostatin for autosomal dominant polycystic kidney and liver disease","volume":"21","author":"MC Hogan","year":"2010","journal-title":"J Am Soc Nephrol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"2936","DOI":"10.1016\/j.transproceed.2012.06.073","article-title":"Sirolimus produced S-shaped effect on adult polycystic kidneys after 2-year treatment","volume":"44","author":"A Soliman","year":"2012","journal-title":"Transplant Proc"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"881","DOI":"10.2215\/CJN.02650313","article-title":"Low-dose rapamycin (sirolimus) effects in autosomal dominant polycystic kidney disease: an open-label randomized controlled pilot study","volume":"9","author":"WE Braun","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1681\/ASN.2009121302","article-title":"Sirolimus therapy to halt the progression of ADPKD","volume":"21","author":"N Perico","year":"2010","journal-title":"J Am Soc Nephrol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/j.1523-1755.2005.00395.x","article-title":"Safety and efficacy of long-acting somatostatin treatment in autosomal-dominant polycystic kidney disease","volume":"68","author":"P Ruggenenti","year":"2005","journal-title":"Kidney Int"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"785","DOI":"10.2215\/CJN.09900915","article-title":"Effect of Sirolimus on Disease Progression in Patients with Autosomal Dominant Polycystic Kidney Disease and CKD Stages 3b-4: SIRENA 2 study group","volume":"11","author":"P Ruggenenti","year":"2016","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"A119","DOI":"10.1053\/j.ajkd.2014.01.444","article-title":"Qualification of total kidney volume as a prognostic biomarker for use in clinical trials evaluating patients with autosomal dominant polycystic kidney disease","volume":"63","author":"R Perrone","year":"2014","journal-title":"Am J Kidney Dis"},{"key":"ref21","unstructured":"European Medicines Agency. Total Kidney Volume (TKV) as a prognostic biomarker for use in clinical trials evaluating patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD). Qualification opinion number EMA\/CHMP\/SAWP\/473433\/2015, <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Regulatory_and_procedural_guideline\/2015\/11\/WC500196569.pdf\" xlink:type=\"simple\">http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Regulatory_and_procedural_guideline\/2015\/11\/WC500196569.pdf<\/ext-link>"},{"key":"ref22","unstructured":"US Food and Drug Administration. Biomarker Qualification Review for Total Kidney Volume, <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.fda.gov\/downloads\/Drugs\/DevelopmentApprovalProcess\/DrugDevelopmentToolsQualificationProgram\/UCM458496.pdf\" xlink:type=\"simple\">http:\/\/www.fda.gov\/downloads\/Drugs\/DevelopmentApprovalProcess\/DrugDevelopmentToolsQualificationProgram\/UCM458496.pdf<\/ext-link>"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1053\/j.ajkd.2015.01.030","article-title":"Total Kidney Volume in Autosomal Dominant Polycystic Kidney Disease: A Biomarker of Disease Progression and Therapeutic Efficacy","volume":"66","author":"A Alam","year":"2015","journal-title":"Am J Kidney Dis"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1046\/j.1523-1755.2003.00185.x","article-title":"Renal structure in early autosomal-dominant polycystic kidney disease (ADPKD): The Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) cohort","volume":"64","author":"AB Chapman","year":"2003","journal-title":"Kidney Int"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/ki.2008.558","article-title":"Increases in kidney volume in autosomal dominant polycystic kidney disease can be detected within 6 months","volume":"75","author":"AD Kistler","year":"2009","journal-title":"Kidney Int"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1097\/00004728-200007000-00019","article-title":"Volumetric measurement of renal cysts and parenchyma using MRI: phantoms and patients with polycystic kidney disease","volume":"24","author":"KT Bae","year":"2000","journal-title":"J Comput Assist Tomogr"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1159\/000355375","article-title":"Novel approach to estimate kidney and cyst volumes using mid-slice magnetic resonance images in polycystic kidney disease: Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP)","volume":"38","author":"KT Bae","year":"2013","journal-title":"Am J Nephrol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1681\/ASN.2013101138","article-title":"Imaging classification of autosomal dominant polycystic kidney disease: a simple model for selecting patients for clinical trials: CRISP Investigators","volume":"26","author":"MV Irazabal","year":"2015","journal-title":"J Am Soc Nephrol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1053\/j.ajkd.2015.06.017","article-title":"Estimation of total kidney volume in autosomal dominant polycystic kidney disease","volume":"66","author":"EM Spithoven","year":"2015","journal-title":"Am J Kidney Dis"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"e92232","DOI":"10.1371\/journal.pone.0092232","article-title":"Clinical characteristics and disease predictors of a large Chinese cohort of patients with autosomal dominant polycystic kidney disease","volume":"9","author":"D Chen","year":"2014","journal-title":"PLoS One"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/ki.2015.71","article-title":"A comparison of ultrasound and magnetic resonance imaging shows that kidney length predicts chronic kidney disease in autosomal dominant polycystic kidney disease: CRISP Investigators","volume":"88","author":"H Bhutani","year":"2015","journal-title":"Kidney Int"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1159\/000381476","article-title":"Kidney volume estimations with ellipsoid equations by magnetic resonance imaging in autosomal dominant polycystic kidney disease","volume":"129","author":"E Higashihara","year":"2015","journal-title":"Nephron"},{"issue":"Suppl 4","key":"ref33","doi-asserted-by":"crossref","first-page":"iv26","DOI":"10.1093\/ndt\/gfu091","article-title":"Building a network of ADPKD reference centres across Europe: the EuroCYST initiative","volume":"29","author":"K Petzold","year":"2014","journal-title":"Nephrol Dial Transplant"},{"key":"ref34","unstructured":"Rasband W: ImageJ, US National Institutes of Health, Bethesda, Maryland, USA, <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/imagej.nih.gov\/ij\" xlink:type=\"simple\">http:\/\/imagej.nih.gov\/ij<\/ext-link>, 2012, 1997."},{"key":"ref35","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s10278-004-1014-6","article-title":"OsiriX: an open-source software for navigating in multidimensional DICOM images","volume":"17","author":"A Rosset","year":"2004","journal-title":"J Digit Imaging"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S1361-8415(97)85005-0","article-title":"Interactive live-wire boundary extraction","volume":"1","author":"WA Barrett","year":"1997","journal-title":"Med Image Anal"},{"key":"ref37","first-page":"41","article-title":"Clinical investigation and statistics in laboratory medicine","author":"RG Jones","year":"1997"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"576","DOI":"10.2215\/CJN.08300815","article-title":"Automated Segmentation of Kidneys from MR Images in Patients with Autosomal Dominant Polycystic Kidney Disease: Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP)","volume":"11","author":"Y Kim","year":"2016","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1016\/j.acra.2015.06.018","article-title":"Reliability of Total Renal Volume Computation in Polycystic Kidney Disease From Magnetic Resonance Imaging","volume":"22","author":"D Turco","year":"2015","journal-title":"Acad Radiol"},{"key":"ref40","doi-asserted-by":"crossref","unstructured":"Racimora D, Vivier P-H, Chandarana H, Rusinek H. Segmentation of polycystic kidneys from MR images. Proc. SPIE 7624, Medical Imaging 2010: Computer-Aided Diagnosis; 76241W-76241W\u201311.","DOI":"10.1117\/12.844361"},{"key":"ref41","unstructured":"Daum V, Helbig H, Janka R, Eckardt K, Zeltner R. Quantitative Measurement of Kidney and Cyst Sizes in Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD). 3rd Russian-Bavarian Conference on Biomedical Engineering 2007;Citeseer:111\u2013115."},{"key":"ref42","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1159\/000324039","article-title":"Assessment of kidney volume in polycystic kidney disease using magnetic resonance imaging without contrast medium","volume":"33","author":"R Mignani","year":"2011","journal-title":"Am J Nephrol"},{"key":"ref43","first-page":"241","article-title":"Automatic total kidney volume measurement on follow-up magnetic resonance images to facilitate monitoring of autosomal dominant polycystic kidney disease progression","volume":"31","author":"TL Kline","year":"2015","journal-title":"Nephrol Dial Transplant"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"387","DOI":"10.2214\/AJR.11.8043","article-title":"Intraobserver and interobserver variability of renal volume measurements in polycystic kidney disease using a semiautomated MR segmentation algorithm","volume":"199","author":"BA Cohen","year":"2012","journal-title":"AJR Am J Roentgenol"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1080\/01621459.1950.10483356","article-title":"Sandomire MM: Sample size required for estimating the standard deviation as a percent of its true value","volume":"45","author":"JA Greenwood","year":"1950","journal-title":"J Amer Statist Assoc"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0178488","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T05:11:09Z","timestamp":1589001069000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0178488"}},"subtitle":[],"editor":[{"given":"David","family":"Long","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,5,30]]},"references-count":45,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2017,5,30]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0178488","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,30]]}}}