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Ther"},{"key":"ref85","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0140-6736(05)60827-6","article-title":"Ultraviolet B and blood pressure","volume":"352","author":"R Krause","year":"1998","journal-title":"The Lancet"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1111\/j.1464-5491.2007.02360.x","article-title":"Vitamin-D improves endothelial function in patients with Type-2 diabetes mellitus and low vitamin-D levels","volume":"25","author":"JA Sugden","year":"2008","journal-title":"Diabet Med"},{"key":"ref87","first-page":"1633","article-title":"Effects of a Short-Term Vitamin D3 and Calcium Supplementation on Blood Pressure and Parathyroid Hormone Levels in Elderly Women","volume":"86","author":"M Pfeifer","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.3945\/ajcn.113.072785","article-title":"Effects of vitamin D supplementation on glucose metabolism, lipid concentrations, inflammation, and oxidative stress in gestational diabetes: a double-blind randomized controlled clinical trial","volume":"98","author":"Z Asemi","year":"2013","journal-title":"Am J Clin Nutr"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1161\/HYPERTENSIONAHA.111.00659","article-title":"Effect of Vitamin D Supplementation on Blood Pressure in Blacks","volume":"61","author":"JP Forman","year":"2013","journal-title":"Hypertension"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.atherosclerosis.2014.04.011","article-title":"Vitamin D and nifedipine in the treatment of Chinese patients with grades I-II essential hypertension: A randomized placebo-controlled trial","volume":"235","author":"WR Chen","year":"2014","journal-title":"Atherosclerosis"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1007\/s00125-014-3313-x","article-title":"Effects of calcium-vitamin D co-supplementation on metabolic profiles in vitamin D insufficient people with type 2 diabetes: a randomised controlled clinical trial","volume":"57","author":"M Tabesh","year":"2014","journal-title":"Diabetologia"},{"key":"ref92","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/MBP.0000000000000091","article-title":"The effect of vitamin D supplementation on blood pressure in patients with elevated blood pressure and vitamin D deficiency: a randomized, double-blind, placebo-controlled trial","volume":"20","author":"H Mozaffari-Khosravi","year":"2015","journal-title":"Blood Pressure Monitoring"},{"key":"ref93","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1159\/000452742","article-title":"Effectiveness of Vitamin D Supplementation for Cardiovascular Health Outcomes","volume":"4","author":"P Veloudi","year":"2016","journal-title":"Pulse"},{"key":"ref94","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.2337\/diacare.27.12.2813","article-title":"Serum 25-hydroxyvitamin D, diabetes, and ethnicity in the Third National Health and Nutrition Examination Survey","volume":"27","author":"R Scragg","year":"2004","journal-title":"Diabetes Care"},{"key":"ref95","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.2337\/dc07-0292","article-title":"Serum 25-hydroxyvitamin D concentration and subsequent risk of type 2 diabetes","volume":"30","author":"C Mattila","year":"2007","journal-title":"Diabetes Care"},{"key":"ref96","doi-asserted-by":"crossref","first-page":"650","DOI":"10.2337\/diacare.29.03.06.dc05-1961","article-title":"Vitamin D and Calcium Intake in Relation to Type 2 Diabetes in Women","volume":"29","author":"AG Pittas","year":"2006","journal-title":"Diabetes Care"},{"key":"ref97","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1097\/EDE.0b013e318176b8ad","article-title":"Serum Vitamin D and Subsequent Occurrence of Type 2 Diabetes","volume":"19","author":"P Knekt","year":"2008","journal-title":"Epidemiology"},{"key":"ref98","doi-asserted-by":"crossref","first-page":"722","DOI":"10.2337\/diacare.29.03.06.dc05-2148","article-title":"Serum 25-hydroxyvitamin D3 concentrations and prevalence of cardiovascular disease among type 2 diabetic patients","volume":"29","author":"M Cigolini","year":"2006","journal-title":"Diabetes Care"},{"key":"ref99","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1001\/archinte.167.11.1159","article-title":"Prevalence of Cardiovascular Risk Factors and the Serum Levels of 25-Hydroxyvitamin D in the United States: Data From the Third National Health and Nutrition Examination Survey","volume":"167","author":"D Martins","year":"2007","journal-title":"Arch Intern Med"},{"key":"ref100","doi-asserted-by":"crossref","first-page":"658","DOI":"10.2337\/dc10-1829","article-title":"Prediabetes and prehypertension in healthy adults are associated with low vitamin D levels","volume":"34","author":"AK Gupta","year":"2011","journal-title":"Diabetes Care"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"476","DOI":"10.4158\/EP09195.RA","article-title":"Vitamin D role and use in prediabetes","volume":"16","author":"E Barengolts","year":"2010","journal-title":"Endocr Pract"},{"key":"ref102","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1007\/s00125-012-2529-x","article-title":"Low serum 25-hydroxyvitamin D level predicts progression to type 2 diabetes in individuals with prediabetes but not with normal glucose tolerance","volume":"55","author":"A Deleskog","year":"2012","journal-title":"Diabetologia"},{"key":"ref103","article-title":"Associations of vitamin D with insulin resistance, obesity, type 2 diabetes, and metabolic syndrome","author":"SJ Wimalawansa","year":"2016","journal-title":"The Journal of Steroid Biochemistry and Molecular Biology"},{"key":"ref104","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0303-7207(88)90169-4","article-title":"Demonstration of a high affinity receptor for 1,25-dihydroxyvitamin D3 in rat pancreas","volume":"60","author":"H Ishida","year":"1988","journal-title":"Mol Cell Endocrinol"},{"key":"ref105","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jsbmb.2004.03.115","article-title":"Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in pancreatic islets","volume":"89\u201390","author":"R Bland","year":"2004","journal-title":"J Steroid Biochem Mol Biol"},{"key":"ref106","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1126\/science.6250216","article-title":"Vitamin D deficiency inhibits pancreatic secretion of insulin","volume":"209","author":"AW Norman","year":"1980","journal-title":"Science"},{"key":"ref107","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1210\/endo-119-1-84","article-title":"Vitamin D3 improves impaired glucose tolerance and insulin secretion in the vitamin D-deficient rat in vivo","volume":"119","author":"C Cade","year":"1986","journal-title":"Endocrinology"},{"key":"ref108","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1210\/endo-113-4-1511","article-title":"Cellular mechanisms of insulin release: the effects of vitamin D deficiency and repletion on rat insulin secretion","volume":"113","author":"BS Chertow","year":"1983","journal-title":"Endocrinology"},{"key":"ref109","doi-asserted-by":"crossref","first-page":"e142","DOI":"10.1111\/j.1464-5491.2012.03672.x","article-title":"Effect of vitamin D supplementation on glycaemic control and insulin resistance: a systematic review and meta-analysis","volume":"29","author":"PS George","year":"2012","journal-title":"Diabet Med"},{"key":"ref110","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40200-015-0130-9","article-title":"Effect of vitamin D supplementation on glycemic control in patients with type 2 diabetes: a systematic review of interventional studies","volume":"14","author":"N Nigil Haroon","year":"2015","journal-title":"J Diabetes Metab Disord"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"16142","DOI":"10.1038\/srep16142","article-title":"The effect of vitamin D supplementation on insulin and glucose metabolism in overweight and obese individuals: systematic review with meta-analysis","volume":"5","author":"M Jamka","year":"2015","journal-title":"Scientific Reports"},{"key":"ref112","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1038\/ejcn.2011.118","article-title":"Vitamin D and type 2 diabetes: a systematic review","volume":"65","author":"J Mitri","year":"2011","journal-title":"Eur J Clin Nutr"},{"key":"ref113","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1210\/er.2012-1000","article-title":"The Nonskeletal Effects of Vitamin D: An Endocrine Society Scientific Statement","volume":"33","author":"CJ Rosen","year":"2012","journal-title":"Endocr Rev"},{"key":"ref114","doi-asserted-by":"crossref","first-page":"980","DOI":"10.2337\/dc06-1994","article-title":"The Effects of Calcium and Vitamin D Supplementation on Blood Glucose and Markers of Inflammation in Nondiabetic Adults","volume":"30","author":"AG Pittas","year":"2007","journal-title":"Diabetes Care"},{"key":"ref115","doi-asserted-by":"crossref","first-page":"701","DOI":"10.2337\/dc07-1829","article-title":"Calcium plus vitamin D supplementation and the risk of incident diabetes in the Women&apos;s Health Initiative","volume":"31","author":"IH de Boer","year":"2008","journal-title":"Diabetes Care"},{"key":"ref116","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1093\/ageing\/afp109","article-title":"Vitamin D supplementation and type 2 diabetes: a substudy of a randomised placebo-controlled trial in older people (RECORD trial)","volume":"38","author":"A Avenell","year":"2009","journal-title":"Age Ageing"},{"key":"ref117","doi-asserted-by":"crossref","first-page":"260","DOI":"10.2337\/dc12-1204","article-title":"High-Dose Vitamin D Supplementation in People With Prediabetes and Hypovitaminosis D","volume":"36","author":"MB Davidson","year":"2013","journal-title":"Diabetes Care"},{"key":"ref118","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1172\/JCI111971","article-title":"Evidence for alteration of the vitamin D-endocrine system in obese subjects","volume":"76","author":"NH Bell","year":"1985","journal-title":"J Clin Invest"},{"key":"ref119","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BF02555135","article-title":"Low circulating vitamin D in obesity","volume":"43","author":"Y Liel","year":"1988","journal-title":"Calcif Tissue Int"},{"key":"ref120","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1381\/096089293765559142","article-title":"Vitamin D Deficiency in the Morbidly Obese","volume":"3","author":"C Buffington","year":"1993","journal-title":"Obes Surg"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1210\/jc.2003-031398","article-title":"The Relationship between Obesity and Serum 1,25-Dihydroxy Vitamin D Concentrations in Healthy Adults","volume":"89","author":"SJ Parikh","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"ref122","doi-asserted-by":"crossref","first-page":"2552","DOI":"10.1172\/JCI116492","article-title":"Human plasma transport of vitamin D after its endogenous synthesis","volume":"91","author":"JG Haddad","year":"1993","journal-title":"J Clin Invest"},{"key":"ref123","article-title":"Volumetric Dilution, Rather Than Sequestration Best Explains the Low Vitamin D Status of Obesity","author":"AT Drincic","year":"2012","journal-title":"Obesity Res"},{"key":"ref124","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1093\/ajcn\/72.3.690","article-title":"Decreased bioavailability of vitamin D in obesity","volume":"72","author":"J Wortsman","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"ref125","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/j.1445-5994.2009.01900.x","article-title":"Body mass index determines sunbathing habits: implications on vitamin D levels","volume":"39","author":"M Kull","year":"2009","journal-title":"Intern Med J"},{"key":"ref126","doi-asserted-by":"crossref","first-page":"e1001383","DOI":"10.1371\/journal.pmed.1001383","article-title":"Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts","volume":"10","author":"KS Vimaleswaran","year":"2013","journal-title":"PLoS Med"},{"key":"ref127","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1006\/bbrc.1993.1717","article-title":"Vitamin D receptor gene expression is up-regulated by 1, 25-dihydroxyvitamin D3 in 3T3-L1 preadipocytes","volume":"193","author":"Y Kamei","year":"1993","journal-title":"Biochem Biophys Res Commun"},{"key":"ref128","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.jsbmb.2008.09.006","article-title":"1alpha,25-Dihydroxyvitamin D hydroxylase in adipocytes","volume":"112","author":"J Li","year":"2008","journal-title":"J Steroid Biochem Mol Biol"},{"key":"ref129","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/ijo.2011.119","article-title":"The link between obesity and low circulating 25-hydroxyvitamin D concentrations: considerations and implications","volume":"36","author":"CP Earthman","year":"2012","journal-title":"Int J Obes (Lond)"},{"key":"ref130","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1681\/ASN.V10102158","article-title":"Antagonistic effects of vitamin D and parathyroid hormone on lipoprotein lipase in cultured adipocytes","volume":"10","author":"U Querfeld","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"ref131","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0306-9877(03)00227-5","article-title":"PTH excess may promote weight gain by impeding catecholamine-induced lipolysis-implications for the impact of calcium, vitamin D, and alcohol on body weight","volume":"61","author":"MF McCarty","year":"2003","journal-title":"Medical Hypotheses"},{"key":"ref132","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.2337\/db06-1656","article-title":"Visceral fat adipokine secretion is associated with systemic inflammation in obese humans","volume":"56","author":"L Fontana","year":"2007","journal-title":"Diabetes"},{"key":"ref133","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.jsbmb.2010.03.018","article-title":"Vitamin D regulates macrophage cholesterol metabolism in diabetes","volume":"121","author":"AE Riek","year":"2010","journal-title":"J Steroid Biochem Mol Biol"},{"key":"ref134","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.cyto.2009.12.006","article-title":"No effect of supplementation with cholecalciferol on cytokines and markers of inflammation in overweight and obese subjects","volume":"50","author":"R Jorde","year":"2010","journal-title":"Cytokine"},{"key":"ref135","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.ejim.2013.03.005","article-title":"Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels\u2014Results from a randomized trial","volume":"24","author":"L Wamberg","year":"2013","journal-title":"Eur J Intern Med"},{"key":"ref136","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1038\/ejcn.2011.106","article-title":"Calcium and vitamin D for obesity: a review of randomized controlled trials","volume":"65","author":"MJ Soares","year":"2011","journal-title":"Eur J Clin Nutr"},{"key":"ref137","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/obr.12162","article-title":"Vitamin D supplementation and body weight status: a systematic review and meta-analysis of randomized controlled trials","volume":"15","author":"K Pathak","year":"2014","journal-title":"Obes Rev"},{"key":"ref138","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1093\/nutrit\/nuv012","article-title":"Effect of vitamin D supplementation alone or with calcium on adiposity measures: a systematic review and meta-analysis of randomized controlled trials","volume":"73","author":"PD Chandler","year":"2015","journal-title":"Nutr Rev"},{"key":"ref139","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.0954-6820.1987.tb10684.x","article-title":"Treatment with one-alpha-hydroxycholecalciferol in middle-aged men with impaired glucose tolerance\u2014a prospective randomized double-blind study","volume":"222","author":"S Ljunghall","year":"1987","journal-title":"Acta Med Scand"},{"key":"ref140","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1001\/archinte.167.9.893","article-title":"Calcium plus vitamin D supplementation and the risk of postmenopausal weight gain","volume":"167","author":"B Caan","year":"2007","journal-title":"Arch Intern Med"},{"key":"ref141","doi-asserted-by":"crossref","first-page":"318","DOI":"10.3109\/09637486.2010.536146","article-title":"Effects of vitamin D supplementation on 25-hydroxyvitamin D, high-density lipoprotein cholesterol, and other cardiovascular disease risk markers in subjects with elevated waist circumference","volume":"62","author":"KC Maki","year":"2011","journal-title":"Int J Food Sci Nutr"},{"key":"ref142","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1530\/EJE-08-0339","article-title":"Supplementation with cholecalciferol does not result in weight reduction in overweight and obese subjects","volume":"159","author":"M Sneve","year":"2008","journal-title":"Eur J Endocrinol"},{"key":"ref143","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.3945\/ajcn.2008.27004","article-title":"Vitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markers","volume":"89","author":"A Zittermann","year":"2009","journal-title":"Am J Clin Nutr"},{"key":"ref144","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/1475-2891-11-78","article-title":"A 12-week double-blind randomized clinical trial of vitamin D3 supplementation on body fat mass in healthy overweight and obese women","volume":"11","author":"A Salehpour","year":"2012","journal-title":"Nutrition Journal"},{"key":"ref145","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.clnu.2012.08.014","article-title":"Impact of vitamin D supplementation during a resistance training intervention on body composition, muscle function, and glucose tolerance in overweight and-\u00e1obese adults","volume":"32","author":"AE Carrillo","year":"2013","journal-title":"Clin Nutr"},{"key":"ref146","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.3945\/ajcn.113.073734","article-title":"Vitamin D3 supplementation during weight loss: a double-blind randomized controlled trial","volume":"99","author":"C Mason","year":"2014","journal-title":"Am J Clin Nutr"},{"key":"ref147","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/jn\/137.2.447","article-title":"High Prevalence of Vitamin D Insufficiency in Black and White Pregnant Women Residing in the Northern United States and Their Neonates","volume":"137","author":"LM Bodnar","year":"2007","journal-title":"J Nutr"},{"key":"ref148","first-page":"750","article-title":"High prevalence of vitamin D deficiency in newborn infants of high-risk mothers","volume":"92","author":"SH Dijkstra","year":"2007","journal-title":"Arch Dis Child"},{"key":"ref149","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1038\/sj.ejcn.1602440","article-title":"Postpartum vitamin D insufficiency and secondary hyperparathyroidism in healthy Danish women","volume":"60","author":"UK Moller","year":"2006","journal-title":"Eur J Clin Nutr"},{"key":"ref150","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.f1169","article-title":"Association between maternal serum 25-hydroxyvitamin D level and pregnancy and neonatal outcomes: systematic review and meta-analysis of observational studies","volume":"346","author":"F Aghajafari","year":"2013","journal-title":"BMJ"},{"key":"ref151","doi-asserted-by":"crossref","first-page":"889","DOI":"10.3109\/14767058.2013.765849","article-title":"Maternal vitamin D status and adverse pregnancy outcomes: a systematic review and meta-analysis","volume":"26","author":"SQ Wei","year":"2013","journal-title":"The Journal of Maternal-Fetal & Neonatal Medicine"},{"key":"ref152","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.placenta.2010.08.015","article-title":"Vitamin D effects on pregnancy and the placenta","volume":"31","author":"JS Shin","year":"2010","journal-title":"Placenta"},{"key":"ref153","doi-asserted-by":"crossref","first-page":"5968","DOI":"10.4049\/jimmunol.1003332","article-title":"Vitamin D and the Regulation of Placental Inflammation","volume":"186","author":"NQ Liu","year":"2011","journal-title":"J Immunol"},{"key":"ref154","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1365-3016.2012.01283.x","article-title":"Vitamin D During Pregnancy and Maternal, Neonatal and Infant Health Outcomes: A Systematic Review and Meta-analysis","volume":"26","author":"A Thorne-Lyman","year":"2012","journal-title":"Paediatric and Perinatal Epidemiology"},{"key":"ref155","first-page":"CD008873","article-title":"Vitamin D supplementation for women during pregnancy","author":"LM De-Regil","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"ref156","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1111\/aogs.12000","article-title":"The impact of vitamin D on pregnancy: a systematic review","volume":"91","author":"HT Christesen","year":"2012","journal-title":"Acta Obstet Gynecol Scand"},{"key":"ref157","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta18450","article-title":"Vitamin D supplementation in pregnancy: A systematic review","volume":"18","author":"NC Harvey","year":"2014","journal-title":"Health Technol Assess"},{"key":"ref158","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/j.fertnstert.2015.02.019","article-title":"Effect of vitamin D supplementation during pregnancy on maternal and neonatal outcomes: a systematic review and meta-analysis of randomized controlled trials","volume":"103","author":"FR P\u00e9rez-L\u00f3pez","year":"2015","journal-title":"Fertility and Sterility"},{"key":"ref159","first-page":"CD008873","article-title":"Pe+\u00a6a-Rosas JP. Vitamin D supplementation for women during pregnancy","author":"LM De-Regil","year":"2016","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"ref160","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/00006250-198609000-00002","article-title":"Vitamin D supplementation in pregnancy: a controlled trial of two methods","volume":"68","author":"E Mallet","year":"1986","journal-title":"Obstet Gynecol"},{"key":"ref161","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/S0271-5317(05)80400-2","article-title":"Effect of pharmacological doses of vitamin D during pregnancy on placental protein status and birth weight","volume":"11","author":"J Kaur","year":"1991","journal-title":"Nutr Res"},{"key":"ref162","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ejogrb.2013.10.010","article-title":"Effect of treatment of vitamin D deficiency and insufficiency during pregnancy on fetal growth indices and maternal weight gain: a randomized clinical trial","volume":"172","author":"S Hashemipour","year":"2014","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"ref163","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1111\/cen.12751","article-title":"Supplementation of vitamin D in pregnancy and its correlation with feto-maternal outcome","volume":"83","author":"A Sablok","year":"2015","journal-title":"Clin Endocrinol"},{"key":"ref164","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1002\/jbmr.463","article-title":"Vitamin D supplementation during pregnancy: Double blind, randomized clinical trial of safety and effectiveness","volume":"26","author":"BW Hollis","year":"2011","journal-title":"J Bone Min Res"},{"key":"ref165","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1475-2891-12-47","article-title":"Randomized placebo-controlled trial of high-dose prenatal third-trimester vitamin D3 supplementation in Bangladesh: the AViDD trial","volume":"12","author":"D Roth","year":"2013","journal-title":"Nutrition Journal"},{"key":"ref166","doi-asserted-by":"crossref","first-page":"2448","DOI":"10.1210\/jc.2013-3491","article-title":"Obstetric and neonatal outcomes of maternal vitamin D supplementation: results of an open-label, randomized controlled trial of antenatal vitamin D supplementation in Pakistani women","volume":"99","author":"N Hossain","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"ref167","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1136\/bmj.280.6216.751","article-title":"Vitamin D supplements in pregnant Asian women: effects on calcium status and fetal growth","volume":"280","author":"OG Brooke","year":"1980","journal-title":"Br Med J"},{"key":"ref168","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1007\/s40618-015-0363-y","article-title":"Vitamin D during pregnancy: why observational studies suggest deficiency and interventional studies show no improvement in clinical outcomes? 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Giovannucci","year":"2006","journal-title":"J Natl Cancer Inst"},{"key":"ref172","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1093\/jnci\/dji022","article-title":"Ultraviolet Radiation Exposure and Risk of Malignant Lymphomas","volume":"97","author":"KE Smedby","year":"2005","journal-title":"J Natl Cancer Inst"},{"key":"ref173","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1080\/01635580701390223","article-title":"Dietary vitamin D and calcium intake and premenopausal breast cancer risk in a German case-control study","volume":"59","author":"S Abbas","year":"2007","journal-title":"Nutr Cancer"},{"key":"ref174","doi-asserted-by":"crossref","first-page":"4153","DOI":"10.1007\/s13277-013-1544-y","article-title":"Systematic review and meta-analysis on vitamin D receptor polymorphisms and cancer risk","volume":"35","author":"Y Xu","year":"2014","journal-title":"Tumor Biol"},{"key":"ref175","first-page":"1","article-title":"The roles of UVB and vitamin D in reducing risk of cancer incidence and mortality: A review of the epidemiology, clinical trials, and mechanisms","author":"M Moukayed","year":"2017","journal-title":"Reviews in Endocrine and Metabolic Disorders"},{"key":"ref176","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jsbmb.2005.06.018","article-title":"Vitamin D and prevention of colorectal cancer","volume":"97","author":"ED Gorham","year":"2005","journal-title":"The Journal of Steroid Biochemistry and Molecular Biology"},{"key":"ref177","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.amepre.2006.11.004","article-title":"Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis","volume":"32","author":"ED Gorham","year":"2007","journal-title":"Am J Prev Med"},{"key":"ref178","article-title":"Meta-analysis of vitamin D, calcium and the prevention of breast cancer","author":"P Chen","year":"2009","journal-title":"Breast Cancer Research and Treatment"},{"key":"ref179","doi-asserted-by":"crossref","first-page":"430","DOI":"10.4251\/wjgo.v6.i11.430","article-title":"Vitamin D and colon cancer","volume":"6","author":"L Klampfer","year":"2014","journal-title":"World J Gastrointest Oncol"},{"key":"ref180","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/nrc3691","article-title":"The role of vitamin D in reducing cancer risk and progression","volume":"14","author":"D Feldman","year":"2014","journal-title":"Nat Rev Cancer"},{"key":"ref181","article-title":"Review: The Impacts of Circulating 25-Hydroxyvitamin D Levels on Cancer Patient Outcomes: A Systematic Review and Meta-Analysis","author":"M Li","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"ref182","first-page":"1","article-title":"Vitamin D and calcium: a systematic review of health outcomes","volume":"183","author":"M Chung","year":"2009","journal-title":"Evid Rep Technol Assess (Full Rep)"},{"key":"ref183","doi-asserted-by":"crossref","first-page":"827","DOI":"10.7326\/0003-4819-155-12-201112200-00005","article-title":"Vitamin D With or Without Calcium Supplementation for Prevention of Cancer and Fractures: An Updated Meta-analysis for the U.S. Preventive Services Task Force","volume":"155","author":"M Chung","year":"2011","journal-title":"Ann Intern Med"},{"key":"ref184","first-page":"CD007469","article-title":"Vitamin D supplementation for prevention of cancer in adults","volume":"6","author":"G Bjelakovic","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"ref185","doi-asserted-by":"crossref","first-page":"e69269","DOI":"10.1371\/journal.pone.0069269","article-title":"Vitamin D Supplementation and Breast Cancer Prevention: A Systematic Review and Meta-Analysis of Randomized Clinical Trials","volume":"8","author":"F Sperati","year":"2013","journal-title":"PLoS ONE"},{"key":"ref186","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/bjc.2014.294","article-title":"Vitamin D supplements and cancer incidence and mortality: a meta-analysis","volume":"111","author":"N Keum","year":"2014","journal-title":"Br J Cancer"},{"key":"ref187","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1093\/ajcn\/85.6.1586","article-title":"Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial","volume":"85","author":"JM Lappe","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"ref188","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1056\/NEJMoa055222","article-title":"Calcium plus Vitamin D Supplementation and the Risk of Colorectal Cancer","volume":"354","author":"J Wactawski-Wende","year":"2006","journal-title":"N Engl J Med"},{"key":"ref189","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.3945\/ajcn.111.015032","article-title":"Calcium and vitamin D supplements and health 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trials","volume":"13","author":"M Lazzeroni","year":"2013","journal-title":"Anticancer Agents Med Chem"},{"key":"ref193","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1001\/jama.2017.2115","article-title":"Effect of vitamin d and calcium supplementation on cancer incidence in older women: A randomized clinical trial","volume":"317","author":"J Lappe","year":"2017","journal-title":"JAMA"},{"key":"ref194","doi-asserted-by":"crossref","first-page":"e0176448","DOI":"10.1371\/journal.pone.0176448","article-title":"Randomized controlled trials of vitamin D and cancer incidence: A modeling study","volume":"12","author":"WB Grant","year":"2017","journal-title":"PLoS ONE"},{"key":"ref195","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1177\/000992287701600106","article-title":"The rachitic lung. Pulmonary findings in 30 infants and children with malnutritional rickets","volume":"16","author":"A Khajavi","year":"1977","journal-title":"Clin Pediatr (Phila)"},{"key":"ref196","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.jsbmb.2006.12.052","article-title":"Vitamin D in the treatment of pulmonary tuberculosis","volume":"103","author":"AR Martineau","year":"2007","journal-title":"J Steroid Biochem Mol Biol"},{"key":"ref197","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1017\/S0950268806007175","article-title":"Epidemic influenza and vitamin D","volume":"134","author":"JJ Cannell","year":"2006","journal-title":"Epidemiol Infect"},{"key":"ref198","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/aje\/kwh227","article-title":"Influenza and the winter increase in mortality in the United States, 1959\u20131999","volume":"160","author":"TA Reichert","year":"2004","journal-title":"Am J Epidemiol"},{"key":"ref199","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1016\/S0140-6736(10)60549-1","article-title":"Global, regional, and national causes of child mortality in 2008: a systematic analysis","volume":"375","author":"RE Black","year":"2010","journal-title":"Lancet"},{"key":"ref200","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1126\/science.1123933","article-title":"Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response","volume":"311","author":"PT Liu","year":"2006","journal-title":"Science"},{"key":"ref201","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.4049\/jimmunol.173.5.2909","article-title":"Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression","volume":"173","author":"TT Wang","year":"2004","journal-title":"J Immunol"},{"key":"ref202","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s11154-011-9195-z","article-title":"Vitamin D metabolism and signaling in the immune system","volume":"13","author":"JH White","year":"2012","journal-title":"Rev Endocr Metab Disord"},{"key":"ref203","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s11882-009-0012-7","article-title":"Vitamin D, respiratory infections, and asthma","volume":"9","author":"A Ginde","year":"2009","journal-title":"Current Allergy and Asthma Reports"},{"key":"ref204","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1001\/archinternmed.2008.560","article-title":"Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey","volume":"169","author":"AA Ginde","year":"2009","journal-title":"Arch Intern Med"},{"key":"ref205","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1093\/ajcn\/86.3.714","article-title":"An association of serum vitamin D concentrations &lt; 40 nmol\/L with acute respiratory tract infection in young Finnish men","volume":"86","author":"I Laaksi","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"ref206","doi-asserted-by":"crossref","first-page":"e11088","DOI":"10.1371\/journal.pone.0011088","article-title":"Serum 25-Hydroxyvitamin D and the Incidence of Acute Viral Respiratory Tract Infections in Healthy Adults","volume":"5","author":"JR Sabetta","year":"2010","journal-title":"PLoS ONE"},{"key":"ref207","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1093\/cid\/cit289","article-title":"Low serum 25-hydroxyvitamin D level and risk of upper respiratory tract infection in children and adolescents","volume":"57","author":"M Science","year":"2013","journal-title":"Clin Infect Dis"},{"key":"ref208","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1017\/S0007114511001991","article-title":"Vitamin D status has a linear association with seasonal infections and lung function in British adults","volume":"106","author":"DJ Berry","year":"2011","journal-title":"Br J Nutr"},{"key":"ref209","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1017\/S0950268814000193","article-title":"Does vitamin D protect against respiratory viral infections?","volume":"142","author":"KJ Bryson","year":"2014","journal-title":"Epidemiol Infect"},{"key":"ref210","doi-asserted-by":"crossref","first-page":"438","DOI":"10.4158\/EP09101.ORR","article-title":"Vitamin D for treatment and prevention of infectious diseases: a systematic review of randomized controlled trials","volume":"15","author":"AV Yamshchikov","year":"2009","journal-title":"Endocr Pract"},{"key":"ref211","doi-asserted-by":"crossref","first-page":"300","DOI":"10.4103\/0976-500X.103685","article-title":"Vitamin D for prevention of respiratory tract infections: A systematic review and meta-analysis","volume":"3","author":"J Charan","year":"2012","journal-title":"J Pharmacol 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of acute respiratory infection: Systematic review of clinical studies","volume":"136","author":"DA Jolliffe","year":"2013","journal-title":"The Journal of Steroid Biochemistry and Molecular Biology"},{"key":"ref216","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1017\/S000711451500207X","article-title":"Vitamin D supplementation for the prevention of childhood acute respiratory infections: a systematic review of randomised controlled trials","volume":"114","author":"L Xiao","year":"2015","journal-title":"Br J Nutr"},{"key":"ref217","first-page":"CD008824","article-title":"Vitamin D supplementation for preventing infections in children under five years of age","author":"MY Yakoob","year":"2016","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"ref218","doi-asserted-by":"crossref","first-page":"e0162996","DOI":"10.1371\/journal.pone.0162996","article-title":"Effect of Vitamin D3 Supplementation on Respiratory Tract Infections in Healthy Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","volume":"11","author":"D Vuichard Gysin","year":"2016","journal-title":"PLoS ONE"},{"key":"ref219","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","article-title":"Assessing the quality of reports of randomized clinical trials: Is blinding necessary?","volume":"17","author":"AR Jadad","year":"1996","journal-title":"Control Clin Trials"},{"key":"ref220","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/S0140-6736(11)61650-4","article-title":"Effect on the incidence of pneumonia of vitamin D supplementation by quarterly bolus dose to infants in Kabul: a randomised controlled superiority trial","volume":"379","author":"S Manaseki-Holland","year":"2012","journal-title":"Lancet"},{"key":"ref221","doi-asserted-by":"crossref","first-page":"d2975","DOI":"10.1136\/bmj.d2975","article-title":"Effect of weekly vitamin D supplements on mortality, morbidity, and growth of low 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(2)","author":"P Brachet","year":"2005"},{"key":"ref226","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/jnr.490280111","article-title":"1,25-Dihydroxyvitamin D3 is a potent inducer of nerve growth factor synthesis","volume":"28","author":"D Wion","year":"1991","journal-title":"J Neurosci Res"},{"key":"ref227","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1096\/fj.14-268342","article-title":"Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior","volume":"29","author":"RP Patrick","year":"2015","journal-title":"FASEB J"},{"key":"ref228","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1007\/s007020070063","article-title":"Vitamin D in schizophrenia, major depression and alcoholism","volume":"107","author":"B Schneider","year":"2000","journal-title":"J Neural 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Neurol"},{"key":"ref232","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s00406-011-0265-8","article-title":"Depression is associated with low levels of 25-hydroxyvitamin D among Jordanian adults: results from a national population survey","volume":"262","author":"HY Jaddou","year":"2012","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"ref233","doi-asserted-by":"crossref","first-page":"4720","DOI":"10.3390\/nu6114720","article-title":"Serum 25-hydroxyvitamin D concentrations and depressive symptoms among young adult men and women","volume":"6","author":"MA Polak","year":"2014","journal-title":"Nutrients"},{"key":"ref234","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1177\/0004867413512383","article-title":"Low vitamin D levels are associated with symptoms of depression in young adult males","volume":"48","author":"LJ Black","year":"2014","journal-title":"Aust N Z J Psychiatry"},{"key":"ref235","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s12603-012-0418-0","article-title":"Serum 25-hydroxyvitamin D levels and the risk of depression: a systematic review and meta-analysis","volume":"17","author":"SY Ju","year":"2013","journal-title":"J Nutr Health Aging"},{"key":"ref236","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1017\/S0007114510002588","article-title":"No associations between serum concentrations of 25-hydroxyvitamin D and parathyroid hormone and depression among US adults","volume":"104","author":"G Zhao","year":"2010","journal-title":"Br J Nutr"},{"key":"ref237","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1038\/ejcn.2009.96","article-title":"Association between serum 25-hydroxyvitamin D and depressive symptoms in Japanese: analysis by survey season","volume":"63","author":"A Nanri","year":"2009","journal-title":"Eur J Clin Nutr"},{"key":"ref238","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.jad.2009.02.002","article-title":"Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly Chinese","volume":"118","author":"A Pan","year":"2009","journal-title":"J Affect Disord"},{"key":"ref239","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.3390\/nu6041501","article-title":"Vitamin D and depression: a systematic review and meta-analysis comparing studies with and without biological flaws","volume":"6","author":"S Spedding","year":"2014","journal-title":"Nutrients"},{"key":"ref240","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1210\/jc.2013-3450","article-title":"Efficacy of vitamin D supplementation in depression in adults: a systematic review","volume":"99","author":"G Li","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"ref241","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1097\/PSY.0000000000000044","article-title":"Vitamin D Supplementation for Depressive Symptoms: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","volume":"76","author":"JAP Shaffer","year":"2014","journal-title":"Psychosom Med"},{"key":"ref242","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.nut.2014.06.017","article-title":"Vitamin D supplementation to reduce depression in adults: Meta-analysis of randomized controlled trials","volume":"31","author":"U Gowda","year":"2015","journal-title":"Nutrition"},{"key":"ref243","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jand.2014.10.023","article-title":"Vitamin D Supplementation and Health-Related Quality of Life: A Systematic Review of the Literature","volume":"115","author":"MR Hoffmann","year":"2015","journal-title":"Journal of the Academy of Nutrition and 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Belcaro","year":"2010","journal-title":"Panminerva Med"},{"key":"ref248","doi-asserted-by":"crossref","first-page":"e25966","DOI":"10.1371\/journal.pone.0025966","article-title":"Effects of Vitamin D Supplementation on Cognitive and Emotional Functioning in Young Adults\u2014A Randomised Controlled Trial","volume":"6","author":"AJ Dean","year":"2011","journal-title":"PLoS ONE"},{"key":"ref249","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.ijgo.2009.01.016","article-title":"Effect of treatment with dydrogesterone or calcium plus vitamin D on the severity of premenstrual syndrome","volume":"105","author":"M Khajehei","year":"2009","journal-title":"Int J Gynaecol Obstet"},{"key":"ref250","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1097\/gme.0b013e31823bcec5","article-title":"Treatment with hormone therapy and calcitriol did not affect depression in older postmenopausal women: no interaction with estrogen and vitamin D receptor genotype polymorphisms","volume":"19","author":"V Yalamanchili","year":"2012","journal-title":"Menopause"},{"key":"ref251","first-page":"151","article-title":"Can vitamin D supplementation prevent winter-time blues? A randomised trial among older women","volume":"10","author":"JC Dumville","year":"2006","journal-title":"J Nutr Health Aging"},{"key":"ref252","doi-asserted-by":"crossref","first-page":"203","DOI":"10.4158\/EP.15.3.203","article-title":"Correlation of symptoms with vitamin D deficiency and symptom response to cholecalciferol treatment: a randomized controlled trial","volume":"15","author":"DS Arvold","year":"2009","journal-title":"Endocr Pract"},{"key":"ref253","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1365-2796.2008.02008.x","article-title":"Effects of vitamin D supplementation on symptoms of depression in overweight and obese subjects: randomized double blind trial","volume":"264","author":"R Jorde","year":"2008","journal-title":"J Intern Med"},{"key":"ref254","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s002130050517","article-title":"Vitamin D<sub>3<\/sub> enhances mood in healthy subjects during winter","volume":"135","author":"ATG Lansdowne","year":"1998","journal-title":"Psychopharmacology"},{"key":"ref255","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1475-2891-3-8","article-title":"Randomized comparison of the effects of the vitamin D3 adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patients","volume":"3","author":"R Vieth","year":"2004","journal-title":"Nutrition Journal"},{"key":"ref256","first-page":"5","article-title":"Vitamin D vs broad spectrum phototherapy in the treatment of seasonal affective disorder","volume":"3","author":"FM Gloth","year":"1999","journal-title":"J Nutr Health Aging"},{"key":"ref257","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1177\/0004867412465022","article-title":"Therapeutic effects of vitamin D as adjunctive therapy to fluoxetine in patients with major depressive disorder","volume":"47","author":"N Khoraminya","year":"2013","journal-title":"Aust N Z J Psychiatry"},{"key":"ref258","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.nut.2010.05.016","article-title":"Vitamin C provision improves mood in acutely hospitalized patients","volume":"27","author":"M Zhang","year":"2011","journal-title":"Nutrition"},{"key":"ref259","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/2046-4053-2-64","article-title":"Efficacy of vitamin D supplementation in depression in adults: a systematic review protocol","volume":"2","author":"G Li","year":"2013","journal-title":"Syst Rev"},{"key":"ref260","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1097\/JCP.0b013e31828f619a","article-title":"The Effect of 2 Different Single Injections of High Dose of Vitamin D on Improving the Depression in Depressed Patients With Vitamin D Deficiency: A Randomized Clinical Trial","volume":"33","author":"H Mozaffari-Khosravi","year":"2013","journal-title":"J Clin Psychopharmacol"},{"key":"ref261","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1001\/archinte.168.15.1629","article-title":"25-Hydroxyvitamin D Levels and the Risk of Mortality in the General Population","volume":"168","author":"ML Melamed","year":"2008","journal-title":"Arch Intern Med"},{"key":"ref262","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1111\/j.1365-2265.2009.03548.x","article-title":"Vitamin D and mortality in older men and women","volume":"71","author":"S Pilz","year":"2009","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref263","doi-asserted-by":"crossref","first-page":"g1903","DOI":"10.1136\/bmj.g1903","article-title":"Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies","volume":"348","author":"R Chowdhury","year":"2014","journal-title":"BMJ"},{"key":"ref264","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.amjopharm.2010.02.004","article-title":"Extraskeletal effects of vitamin D in older adults: Cardiovascular disease, mortality, mood, and cognition","volume":"8","author":"K Barnard","year":"2010","journal-title":"Am J Geriatr Pharmacother"},{"key":"ref265","first-page":"1379","article-title":"Vitamin D and Mortality","volume":"36","author":"S Pilz","year":"2016","journal-title":"Anticancer Res"},{"key":"ref266","doi-asserted-by":"crossref","first-page":"e0170791","DOI":"10.1371\/journal.pone.0170791","article-title":"Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium","volume":"12","author":"M Gaksch","journal-title":"PLoS ONE"},{"key":"ref267","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1056\/NEJMra070553","article-title":"Vitamin D Deficiency","volume":"357","author":"MF Holick","year":"2007","journal-title":"N Engl J Med"},{"key":"ref268","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1365-2265.2005.02226.x","article-title":"Vitamin D and the elderly","volume":"62","author":"L Mosekilde","year":"2005","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref269","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1001\/archinte.167.16.1730","article-title":"Vitamin D Supplementation and Total Mortality: A Meta-analysis of Randomized Controlled Trials","volume":"167","author":"P Autier","year":"2007","journal-title":"Arch Intern Med"},{"key":"ref270","first-page":"CD007470","article-title":"Vitamin D supplementation for prevention of mortality in adults","author":"G Bjelakovic","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"ref271","first-page":"CD007470","article-title":"Vitamin D supplementation for prevention of mortality in adults","volume":"1","author":"G Bjelakovic","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"ref272","doi-asserted-by":"crossref","first-page":"2670","DOI":"10.1210\/jc.2011-3328","article-title":"Vitamin D with Calcium Reduces Mortality: Patient Level Pooled Analysis of 70,528 Patients from Eight Major Vitamin D Trials","volume":"97","author":"L Rejnmark","year":"2012","journal-title":"J Clin Endocrin Metab"},{"key":"ref273","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1046\/j.1532-5415.2003.51101.x","article-title":"A randomized, controlled trial of quadriceps resistance exercise and vitamin D in frail older people: the Frailty Interventions Trial in Elderly Subjects (FITNESS)","volume":"51","author":"NK Latham","year":"2003","journal-title":"J Am Geriatr Soc"},{"key":"ref274","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1093\/ageing\/afj080","article-title":"Vitamin D supplementation and the prevention of fractures and falls: results of a randomised trial in elderly people in residential accommodation","volume":"35","author":"M Law","year":"2006","journal-title":"Age Ageing"},{"key":"ref275","article-title":"Effect of vitamin D on all-cause mortality in heart failure (EVITA): a 3-year randomized clinical trial with 4000 IU vitamin D daily","author":"A Zittermann","year":"2017","journal-title":"Eur Heart J"},{"key":"ref276","article-title":"Vitamin D supplementation for prevention of mortality in adults","author":"G Bjelakovic","year":"2014","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"ref277","doi-asserted-by":"crossref","first-page":"e0115850","DOI":"10.1371\/journal.pone.0115850","article-title":"A Meta-Analysis of High Dose, Intermittent Vitamin D Supplementation among Older Adults","volume":"10","author":"YT Zheng","year":"2015","journal-title":"PLoS ONE"},{"key":"ref278","article-title":"Vitamin D Supplementation Trials Aimed at Reducing Mortality Have Much Higher Power When Focusing on People with Low Serum 25-Hydroxyvitamin D Concentrations","author":"H Brenner","year":"2017","journal-title":"J Nutr"},{"key":"ref279","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1056\/NEJMoa055218","article-title":"Calcium plus vitamin D supplementation and the risk of fractures","volume":"354","author":"RD Jackson","year":"2006","journal-title":"N Engl J Med"},{"key":"ref280","doi-asserted-by":"crossref","first-page":"3289","DOI":"10.1158\/1055-9965.EPI-08-1066","article-title":"Are Clinical Trials the &quot;Gold Standard&quot; for Cancer Prevention Research?","volume":"17","author":"AR Kristal","year":"2008","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref281","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1017\/S1368980014002304","article-title":"Controlled trials of vitamin D, causality and type 2 statistical error","volume":"19","author":"OI Gillie","year":"2016","journal-title":"Public Health Nutr"},{"key":"ref282","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/nure.12090","article-title":"Guidelines for optimizing design and analysis of clinical studies of nutrient effects","volume":"72","author":"RP Heaney","year":"2014","journal-title":"Nutr Rev"},{"key":"ref283","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1210\/jc.2010-2704","article-title":"The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know","volume":"96","author":"AC Ross","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"ref284","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1210\/jc.2011-0385","article-title":"Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline","volume":"96","author":"MF Holick","year":"2011","journal-title":"J Clin Endocrin Metab"},{"key":"ref285","doi-asserted-by":"crossref","first-page":"4619","DOI":"10.1210\/jc.2013-2653","article-title":"The Role of the Parent Compound Vitamin D with Respect to Metabolism and Function: Why Clinical Dose Intervals Can Affect Clinical Outcomes","volume":"98","author":"BW Hollis","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"ref286","doi-asserted-by":"crossref","first-page":"14875","DOI":"10.1038\/srep14875","article-title":"Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal gland","volume":"5","author":"AT Slominski","year":"2015","journal-title":"Sic Rep"},{"key":"ref287","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1161\/CIRCRESAHA.109.207019","article-title":"Whole Body UVA Irradiation Lowers Systemic Blood Pressure by Release of Nitric Oxide From Intracutaneous Photolabile Nitric Oxide Derivates","volume":"105","author":"C Opl\u00f6nder","year":"2009","journal-title":"Circ Res"},{"key":"ref288","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1038\/jid.2014.33","article-title":"An Unexpected Role: UVA-Induced Release of Nitric Oxide from Skin May Have Unexpected Health Benefits","volume":"134","author":"GM Halliday","year":"2014","journal-title":"J Invest Dermatol"},{"key":"ref289","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1038\/jid.2014.27","article-title":"UVA Irradiation of Human Skin Vasodilates Arterial Vasculature and Lowers Blood Pressure Independently of Nitric Oxide Synthase","volume":"134","author":"D Liu","year":"2014","journal-title":"J Invest Dermatol"},{"key":"ref290","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1753-4887.2012.00544.x","article-title":"Vitamin D and dental caries in controlled clinical trials: systematic review and meta-analysis","volume":"71","author":"PP Hujoel","year":"2013","journal-title":"Nutr 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Trials"},{"key":"ref294","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s12020-017-1290-9","article-title":"Vitamin D supplementation in the prevention and management of major chronic diseases not related to mineral homeostasis in adults: research for evidence and a scientific statement from the European society for clinical and economic aspects of osteoporosis and osteoarthritis (ESCEO)","volume":"56","author":"L Cianferotti","year":"2017","journal-title":"Endocrine"},{"key":"ref295","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3945\/jn.112.169482","article-title":"Vitamin D Intake and Season Modify the Effects of the GC and CYP2R1 Genes on 25-Hydroxyvitamin D Concentrations","volume":"143","author":"CD Engelman","year":"2013","journal-title":"J Nutr"},{"key":"ref296","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1093\/ajcn\/85.3.860","article-title":"Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and 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Temporal Relationship between Vitamin D Status and Parathyroid Hormone in the United States","volume":"10","author":"MH Kroll","year":"2015","journal-title":"PLoS ONE"},{"key":"ref298","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jns.2011.08.044","article-title":"Seasonal, gestational and postnatal influences on multiple sclerosis: The beneficial role of a vitamin D supplementation during early life","volume":"311","author":"DA Fernandes de Abreu","year":"2011","journal-title":"Journal of the Neurological Sciences"},{"key":"ref299","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2014.00248","article-title":"Vitamin D: a critical and essential micronutrient for human health","volume":"5","author":"I Bendik","year":"2014","journal-title":"Frontiers in Physiology"},{"key":"ref300","first-page":"295","article-title":"The Environment and Disease: Association or Causation?","volume":"58","author":"AB Hill","year":"1965","journal-title":"Proc R Soc Med"},{"key":"ref301","doi-asserted-by":"crossref","first-page":"549","DOI":"10.3109\/00365513.2015.1057898","article-title":"Standardizing serum 25-hydroxyvitamin D data from four Nordic population samples using the Vitamin D Standardization Program protocols: Shedding new light on vitamin D status in Nordic individuals","volume":"75","author":"KD Cashman","year":"2015","journal-title":"Scand J Clin Lab Invest"},{"key":"ref302","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.3945\/ajcn.112.057182","article-title":"Evaluation of Vitamin D Standardization Program protocols for standardizing serum 25-hydroxyvitamin D data: a case study of the program&apos;s potential for national nutrition and health surveys","volume":"97","author":"KD Cashman","year":"2013","journal-title":"Am J Clin Nutr"},{"key":"ref303","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.3945\/ajcn.114.103689","article-title":"Standardizing 25-hydroxyvitamin D values from the Canadian Health Measures Survey","volume":"102","author":"K Sarafin","year":"2015","journal-title":"Am J Clin Nutr"},{"key":"ref304","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1007\/s00198-017-3978-3","article-title":"Cost effective measures to standardize serum 25(OH)D values from completed studies","volume":"28","author":"CT Sempos","year":"2017","journal-title":"Osteoporos Int"},{"key":"ref305","article-title":"Vitamin D measurement standardization: The way out of the chaos","author":"N Binkley","year":"2016","journal-title":"J Steroid Biochem Mol Biol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0180512","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T15:46:24Z","timestamp":1659195984000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0180512"}},"subtitle":[],"editor":[{"given":"Andrzej T","family":"Slominski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,7,7]]},"references-count":305,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2017,7,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0180512","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,7]]}}}