{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:36:03Z","timestamp":1790019363450,"version":"4.0.1"},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T00:00:00Z","timestamp":1502323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01 CA192627"],"award-info":[{"award-number":["R01 CA192627"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"name":"SAMRC\/WITS Common Epith1elial Cancer Research Centre (CECRC)"},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA13696"],"award-info":[{"award-number":["P30 CA13696"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0182125","type":"journal-article","created":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T14:02:02Z","timestamp":1502373722000},"page":"e0182125","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Breast conservation surgery versus total mastectomy among women with localized breast cancer in Soweto, South Africa"],"prefix":"10.1371","volume":"12","author":[{"given":"Herbert","family":"Cubasch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"Joffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Ruff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Dietz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan","family":"Rosenbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivashni","family":"Murugan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming Tsai","family":"Chih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oluwatosin","family":"Ayeni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Dickens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Crew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith S.","family":"Jacobson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred","family":"Neugut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,8,10]]},"reference":[{"key":"ref1","unstructured":"J.F., I.S., al MEe: Cancer Incidence and Mortality Worldwide, IARC CancerBase No. 11. GLOBOCAN 2012 v10, Lyon, France: International Agency for Research on Cancer, 2013."},{"issue":"1","key":"ref2","first-page":"7","article-title":"Cancer statistics, 2016","volume":"66","author":"RL Siegel","year":"2016","journal-title":"CA: a cancer journal for clinicians"},{"issue":"3","key":"ref3","first-page":"467","article-title":"Breast cancer in Sub-Saharan Africa: opportunities for prevention","volume":"144","author":"LA Brinton","year":"2014"},{"key":"ref4","unstructured":"World Development Indicators. Health risk factors and future challenges 2012."},{"issue":"4","key":"ref5","doi-asserted-by":"crossref","first-page":"e1001418","DOI":"10.1371\/journal.pmed.1001418","article-title":"Life expectancies of South African adults starting antiretroviral treatment: collaborative analysis of cohort studies","volume":"10","author":"LF Johnson","year":"2013","journal-title":"PLoS Med"},{"key":"ref6","unstructured":"Cancer in South Africa, Full Report: National Cancer Registry. 2000. http:\/\/www.nioh.ac.za\/assets\/files\/2000-Cancer-Report-Full.pdf<\/ext-link>."},{"key":"ref7","unstructured":"Cancer in South Africa, Full Report. National Cancer Registry. 2011. http:\/\/www.nioh.ac.za\/assets\/files\/NCR_Final_2011_tables(1).pdf<\/ext-link>."},{"issue":"1","key":"ref8","first-page":"6","article-title":"Comparing radical MASTECTOMY with quadrantectomy, axillary dissection, and radiotherapy in patients with small cancers of the breast","volume":"305","author":"U Veronesi","year":"1981"},{"issue":"11","key":"ref9","first-page":"665","article-title":"Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer","volume":"312","author":"B Fisher","year":"1985"},{"issue":"16","key":"ref10","first-page":"1233","article-title":"Twenty-year follow-up of a randomized trial comparing total TM, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer","volume":"347","author":"B Fisher","year":"2002"},{"issue":"16","key":"ref11","first-page":"1227","article-title":"Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical TM for early breast cancer","volume":"347","author":"U Veronesi","year":"2002"},{"issue":"01","key":"ref12","first-page":"71","article-title":"Tumor-specific immediate reconstruction in breast cancer patients","volume":"11","author":"WP Audretsch","year":"1998"},{"issue":"14","key":"ref13","first-page":"2396","article-title":"Patterns and Correlates of Adjuvant Radiotherapy Receipt After Lumpectomy and After TM for Breast Cancer","volume":"28","author":"R Jagsi","year":"2010"},{"key":"ref14","article-title":"Disparities in the Local Management of Breast Cancer in the US according to Health Insurance Status","author":"TM Churilla","year":"2016"},{"issue":"9","key":"ref15","first-page":"2173","article-title":"Stage at breast cancer diagnosis and distance from diagnostic hospital in a periurban setting: a South African public hospital case series of over 1,000 women","volume":"135","author":"C Dickens","year":"2014"},{"issue":"1","key":"ref16","first-page":"177","article-title":"Breast cancer characteristics and HIV among 1,092 women in Soweto, South Africa","volume":"140","author":"H Cubasch","year":"2013"},{"issue":"5","key":"ref17","first-page":"R84","article-title":"Breast cancer receptor status and stage at diagnosis in over 1,200 consecutive public hospital patients in Soweto, South Africa: a case series","volume":"15","author":"VA McCormack","year":"2013"},{"issue":"5","key":"ref18","first-page":"1375","article-title":"Improving breast cancer surgery: a classification and quadrant per quadrant atlas for oncoplastic surgery","volume":"17","author":"KB Clough","year":"2010"},{"issue":"11","key":"ref19","doi-asserted-by":"crossref","first-page":"e48883","DOI":"10.1371\/journal.pone.0048883","article-title":"The current waist circumference cut point used for the diagnosis of metabolic syndrome in sub-Saharan African women is not appropriate","volume":"7","author":"NJ Crowther","year":"2012","journal-title":"PloS one"},{"issue":"3","key":"ref20","first-page":"256","article-title":"Oncoplastic reduction mammoplasty for breast cancer in women with macromastia: long term aesthetic, functional and satisfaction outcomes","volume":"20","author":"M Emiroglu","year":"2016","journal-title":"Contemporary oncology"},{"issue":"6","key":"ref21","first-page":"1573","article-title":"Vertical versus Wise pattern breast reduction: patient satisfaction, revision rates, and complications","volume":"112","author":"N Cruz-Korchin","year":"2003"},{"issue":"4","key":"ref22","first-page":"252","article-title":"Cancer treatment and survivorship statistics, 2014","volume":"64","author":"CE DeSantis","year":"2014","journal-title":"CA: a cancer journal for clinicians"},{"key":"ref23","first-page":"1","article-title":"Relationships between poverty and AIDS Illness in South Africa: an investigation of urban and rural households in KwaZulu-Natal","author":"JI Steinert","year":"2016"},{"issue":"1","key":"ref24","first-page":"9","article-title":"Nationwide trends in TM for early-stage breast cancer","volume":"150","author":"KL Kummerow","year":"2015"},{"issue":"4","key":"ref25","first-page":"1129","article-title":"Which eligible breast conservation patients choose TM in the setting of newly diagnosed breast cancer?","volume":"19","author":"CD Adkisson","year":"2012"},{"issue":"4","key":"ref26","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1524-4741.2012.01245.x","article-title":"Increasing TM Rates Among all Age Groups for Early Stage Breast Cancer: A 10-Year Study of Surgical Choice","volume":"18","author":"AE Dragun","year":"2012","journal-title":"The breast journal"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"S110","DOI":"10.1016\/j.breast.2013.07.021","article-title":"Who should not undergo breast conservation?","volume":"22","author":"MV Nijenhuis","year":"2013","journal-title":"The Breast"},{"issue":"3","key":"ref28","first-page":"284","article-title":"Surgical resection margins after breast-conserving surgery: Senonetwork recommendations","volume":"2016","author":"V Galimberti","year":"2016"},{"issue":"3","key":"ref29","first-page":"704","article-title":"Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer","volume":"21","author":"MS Moran","year":"2014"},{"issue":"1","key":"ref30","first-page":"108","article-title":"Taking on breast cancer in East Africa: global challenges in breast cancer","volume":"27","author":"EJ Kantelhardt","year":"2015"},{"issue":"2","key":"ref31","first-page":"78","article-title":"Fear of TM: the most common factor responsible for late presentation of carcinoma of the breast in Nigeria","volume":"3","author":"A Ajekigbe","year":"1991"},{"issue":"4","key":"ref32","first-page":"106","article-title":"Delayed treatment of symptomatic breast cancer: the experience from Kaduna, Nigeria","volume":"46","author":"A Ukwenya","year":"2008","journal-title":"South African Journal of Surgery"},{"issue":"2","key":"ref33","first-page":"276","article-title":"Patients\u2019 refusal of surgery strongly impairs breast cancer survival","volume":"242","author":"HM Verkooijen","year":"2005"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0182125","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T10:17:30Z","timestamp":1540030650000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0182125"}},"subtitle":[],"editor":[{"given":"Sudeep","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,8,10]]},"references-count":33,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2017,8,10]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0182125","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,10]]}}}