{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T23:04:21Z","timestamp":1774479861906,"version":"3.50.1"},"reference-count":63,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2017,8,8]],"date-time":"2017-08-08T00:00:00Z","timestamp":1502150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31501965"],"award-info":[{"award-number":["31501965"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development program of China","doi-asserted-by":"crossref","award":["2016YFD0501201"],"award-info":[{"award-number":["2016YFD0501201"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0182550","type":"journal-article","created":{"date-parts":[[2017,8,9]],"date-time":"2017-08-09T15:08:31Z","timestamp":1502291311000},"page":"e0182550","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Comparison of porous and nano zinc oxide for replacing high-dose dietary regular zinc oxide in weaning piglets"],"prefix":"10.1371","volume":"12","author":[{"given":"Lina","family":"Long","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiashun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonggang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0734-4407","authenticated-orcid":true,"given":"Hengjia","family":"Ni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yulong","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2017,8,8]]},"reference":[{"issue":"4","key":"ref1","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.3390\/ma7042833","article-title":"Zinc Oxide\u2014From Synthesis to Application: A Review","volume":"7","author":"A Kolodziejczakradzimska","year":"2014","journal-title":"Materials"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"041301","DOI":"10.1063\/1.1992666","article-title":"A comprehensive review of ZnO materials and devices","volume":"98","author":"U Ozgur","year":"2005","journal-title":"Journal of Applied Physics"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"e87007","DOI":"10.1371\/journal.pone.0087007","article-title":"Dietary Enterococcus faecium NCIMB 10415 and Zinc Oxide Stimulate Immune Reactions to Trivalent Influenza Vaccination in Pigs but Do Not Affect Virological Response upon Challenge Infection","volume":"9","author":"Z Wang","year":"2014","journal-title":"PLoS ONE"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"934","DOI":"10.2527\/2001.794934x","article-title":"Effect of pharmacological concentrations of zinc oxide with or without the inclusion of an antibacterial agent on nursery pig performance","volume":"79","author":"GM Hill","year":"2001","journal-title":"Journal of Animal Science"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.progsurf.2006.12.002","article-title":"The chemistry and physics of zinc oxide surfaces","volume":"82","author":"C Woll","year":"2007","journal-title":"Progress in Surface Science"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.physe.2015.01.005","article-title":"Utilization of photocatalytic ZnO nanoparticles for deactivation of safranine dye and their applications for statistical analysis","volume":"69","author":"R Wahab","year":"2015","journal-title":"Physica E: Low-dimensional Systems and Nanostructures"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.jhazmat.2013.01.046","article-title":"Comparative study of respiratory tract immune toxicity induced by three sterilisation nanoparticles: silver, zinc oxide and titanium dioxide","volume":"248","author":"H Liu","year":"2013","journal-title":"Journal of hazardous materials"},{"issue":"2","key":"ref8","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s12011-012-9422-9","article-title":"Zinc Oxide\u2013Montmorillonite Hybrid Influences Diarrhea, Intestinal Mucosal Integrity, and Digestive Enzyme Activity in Weaned Pigs","volume":"149","author":"CH Hu","year":"2012","journal-title":"Biol Trace Elem Res"},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1524-475X.2006.00179.x","article-title":"Zinc in wound healing: theoretical, experimental, and clinical aspects","volume":"15","author":"AB Lansdown","year":"2007","journal-title":"Wound Repair and Regeneration"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.colsurfb.2014.02.038","article-title":"ZnO nanoparticles induced oxidative stress and apoptosis in HepG2 and MCF-7 cancer cells and their antibacterial activity","volume":"117","author":"R Wahab","year":"2014","journal-title":"Colloids and Surfaces B: Biointerfaces"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"19950","DOI":"10.1038\/srep19950","article-title":"Self-Styled ZnO Nanostructures Promotes the Cancer Cell Damage and Supresses the Epithelial Phenotype of Glioblastoma","volume":"6","author":"R Wahab","year":"2016","journal-title":"Scientific Reports"},{"issue":"2","key":"ref12","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.antiviral.2011.08.017","article-title":"Virostatic potential of micro\u2013nano filopodia-like ZnO structures against herpes simplex virus-1","volume":"92","author":"YK Mishra","year":"2011","journal-title":"Antiviral Research"},{"issue":"3\u20134","key":"ref13","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0378-1135(99)00202-3","article-title":"Experimental models of porcine post-weaning colibacillosis and their relationship to post-weaning diarrhoea and digestive disorders as encountered in the field","volume":"72","author":"F Madec","year":"2000","journal-title":"Veterinary Microbiology"},{"issue":"1","key":"ref14","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1751-0147-50-21","article-title":"Risk factors for post-weaning diarrhoea on piglet producing farms in Finland","volume":"50","author":"T Laine","year":"2008","journal-title":"Acta Veterinaria Scandinavica"},{"key":"ref15","unstructured":"Poulsen HD. Zinc oxide for weaned pigs. Rome, Italy: 4th Annu. Meet. Eur. Assoc. Anim. Prod. EAAP; 1989. p. 8\u201310 in Proc."},{"issue":"12","key":"ref16","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.jnutbio.2006.12.022","article-title":"Dietary supplementation with zinc oxide decreases expression of the stem cell factor in the small intestine of weanling pigs","volume":"18","author":"D Ou","year":"2007","journal-title":"Journal of Nutritional Biochemistry"},{"issue":"3","key":"ref17","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s12011-013-9638-3","article-title":"Effects of Pharmacological Concentrations of Dietary Zinc Oxide on Growth of Post-weaning Pigs: A Meta-analysis","volume":"152","author":"J Sales","year":"2013","journal-title":"Biol Trace Elem Res"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"581","DOI":"10.2527\/2004.822581x","article-title":"Effect of phosphorylated mannans and pharmacological additions of zinc oxide on growth and immunocompetence of weanling pigs","volume":"82","author":"ME Davis","year":"2004","journal-title":"Journal of Animal Science"},{"issue":"6\u20137","key":"ref19","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.ijmm.2013.06.004","article-title":"The broader context of antibiotic resistance: Zinc feed supplementation of piglets increases the proportion of multi-resistant Escherichia coli in vivo","volume":"303","author":"C Bednorz","year":"2013","journal-title":"International Journal of Medical Microbiology"},{"issue":"7","key":"ref20","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.2527\/1996.7471584x","article-title":"Zinc concentration in tissues and performance of weanling pigs fed pharmacological levels of zinc from ZnO, Zn-methionine, Zn-lysine, or ZnSO4","volume":"74","author":"TC Schell","year":"1996","journal-title":"Journal of Animal Science"},{"issue":"2","key":"ref21","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.microc.2009.09.014","article-title":"A review of heavy metal contaminations in urban soils, urban road dusts and agricultural soils from China","volume":"94","author":"B Wei","year":"2010","journal-title":"Microchemical Journal"},{"issue":"1","key":"ref22","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/2055-0391-56-29","article-title":"Effects of a lipid-encapsulated zinc oxide supplement on growth performance and intestinal morphology and digestive enzyme activities in weanling pigs","volume":"56","author":"I Jang","year":"2014","journal-title":"Journal of Animal Science and Technology"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"436","DOI":"10.2527\/jas.53833","article-title":"Zinc oxide at low supplementation level improves productive performance and health status of piglets","volume":"90","author":"J Morales","year":"2012","journal-title":"Journal of Animal Science"},{"issue":"4","key":"ref24","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.2527\/jas.2014-8580","article-title":"Diosmectite-zinc oxide composite improves intestinal barrier restoration and modulates TGF-\u03b21, ERK1\/2, and Akt in piglets after acetic acid challenge","volume":"93","author":"ZH Song","year":"2015","journal-title":"Journal of Animal Science"},{"issue":"1","key":"ref25","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1743-8977-10-9","article-title":"Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration","volume":"10","author":"W Cho","year":"2013","journal-title":"Particle and Fibre Toxicology"},{"issue":"4","key":"ref26","doi-asserted-by":"crossref","first-page":"e0122893","DOI":"10.1371\/journal.pone.0122893","article-title":"Effects of Dietary Supplementation with Glutamate and Aspartate on Diquat-Induced Oxidative Stress in Piglets","volume":"10","author":"J Yin","year":"2015","journal-title":"PLoS ONE"},{"issue":"6","key":"ref27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0097815","article-title":"Chlorogenic Acid Decreases Intestinal Permeability and Increases Expression of Intestinal Tight Junction Proteins in Weaned Rats Challenged with LPS","volume":"9","author":"Z Ruan","year":"2014","journal-title":"PLoS ONE"},{"issue":"1","key":"ref28","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1186\/s12917-016-0872-8","article-title":"Chitosan oligosaccharide affects antioxidant defense capacity and placental amino acids transport of sows","volume":"12","author":"C Xie","year":"2016","journal-title":"BMC Veterinary Research"},{"issue":"2","key":"ref29","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.tvjl.2009.02.010","article-title":"Up-regulated expression of peroxisome proliferator-activated receptor \u03b3 in the hypothalamic\u2013pituitary\u2013adrenal axis of weaned pigs after Escherichia coli lipopolysaccharide challenge","volume":"184","author":"YL Liu","year":"2010","journal-title":"The Veterinary Journal"},{"issue":"7","key":"ref30","doi-asserted-by":"crossref","first-page":"947","DOI":"10.7150\/ijbs.7.947","article-title":"Molecular characterization of transcriptome-wide interactions between highly pathogenic porcine reproductive and respiratory syndrome virus and porcine alveolar macrophages in vivo","volume":"7","author":"P Zhou","year":"2011","journal-title":"Int J Biol Sci"},{"key":"ref31","article-title":"Oregano Essential Oil Improves Intestinal Morphology and Expression of Tight Junction Proteins Associated with Modulation of Selected Intestinal Bacteria and Immune Status in a Pig Model","volume":"2016","author":"Y Zou","year":"2016","journal-title":"BioMed Research International"},{"issue":"11","key":"ref32","doi-asserted-by":"crossref","first-page":"5009","DOI":"10.2527\/jas.2013-6690","article-title":"Effect of dietary zinc oxide on jejunal morphological and immunological characteristics in weaned piglets","volume":"92","author":"P Liu","year":"2014","journal-title":"Journal of Animal Science"},{"key":"ref33","article-title":"Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells","volume":"2016","author":"Y Zou","year":"2016","journal-title":"Oxidative Medicine and Cellular Longevity"},{"issue":"1","key":"ref34","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.livsci.2007.01.026","article-title":"Zinc is involved in regulation of secretion from intestinal epithelium in weaned piglets","volume":"108","author":"D Carlson","year":"2007","journal-title":"Livestock Science"},{"issue":"4","key":"ref35","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.cbpb.2004.02.011","article-title":"Influence of weaning and effect of post weaning dietary zinc and copper on electrophysiological response to glucose, theophylline and 5-HT in piglet small intestinal mucosa","volume":"137","author":"D Carlson","year":"2004","journal-title":"Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology"},{"issue":"2","key":"ref36","doi-asserted-by":"crossref","first-page":"447S","DOI":"10.1093\/ajcn\/68.2.447S","article-title":"Zinc and immune function: the biological basis of altered resistance to infection","volume":"68","author":"AH Shankar","year":"1998","journal-title":"The American Journal of Clinical Nutrition"},{"issue":"2","key":"ref37","doi-asserted-by":"crossref","first-page":"e56405","DOI":"10.1371\/journal.pone.0056405","article-title":"Ex vivo-growth response of porcine small intestinal bacterial communities to pharmacological doses of dietary zinc oxide","volume":"8","author":"IC Starke","year":"2013","journal-title":"PLoS ONE"},{"issue":"19","key":"ref38","doi-asserted-by":"crossref","first-page":"6689","DOI":"10.1128\/AEM.03075-09","article-title":"Bar-coded pyrosequencing of 16S rRNA gene amplicons reveals changes in ileal porcine bacterial communities due to high dietary zinc intake","volume":"76","author":"W Vahjen","year":"2010","journal-title":"Applied and Environmental Microbiology"},{"issue":"1","key":"ref39","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2527\/jas.2014-8286","article-title":"Effect of added zinc in diets with ractopamine hydrochloride on growth performance, carcass characteristics, and ileal mucosal inflammation mRNA expression of finishing pigs","volume":"93","author":"C Paulk","year":"2015","journal-title":"Journal of Animal Science"},{"issue":"3","key":"ref40","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.vetmic.2012.06.019","article-title":"Antiviral activity of zinc salts against transmissible gastroenteritis virus in vitro","volume":"160","author":"Z Wei","year":"2012","journal-title":"Veterinary Microbiology"},{"issue":"3","key":"ref41","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/09064709509415847","article-title":"Zinc oxide for weanling piglets","volume":"45","author":"HD Poulsen","year":"1995","journal-title":"Acta Agriculturae Scandinavica A-Animal Sciences"},{"issue":"5","key":"ref42","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0922-338X(98)80165-7","article-title":"Hydrogen peroxide as an antibacterial factor in zinc oxide powder slurry","volume":"86","author":"J Sawai","year":"1998","journal-title":"Journal of Fermentation and Bioengineering"},{"issue":"7","key":"ref43","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S1466-6049(01)00197-0","article-title":"Influence of particle size on the antibacterial activity of zinc oxide","volume":"3","author":"O Yamamoto","year":"2001","journal-title":"International Journal of Inorganic Materials"},{"issue":"3","key":"ref44","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1093\/jn\/121.3.338","article-title":"The Influence of Zinc-Binding Ligands in Fetal Circulation on Zinc Clearance Across the In Situ Perfused Guinea Pig Placenta","volume":"121","author":"PG Paterson","year":"1991","journal-title":"Journal of Nutrition"},{"issue":"5","key":"ref45","doi-asserted-by":"crossref","first-page":"F532","DOI":"10.1152\/ajprenal.1981.241.5.F532","article-title":"Renal tubular handling of zinc in the dog","volume":"241","author":"W Victery","year":"1981","journal-title":"American Journal of Physiology-Renal Physiology"},{"issue":"5","key":"ref46","doi-asserted-by":"crossref","first-page":"e0124150","DOI":"10.1371\/journal.pone.0124150","article-title":"A Drosophila Model Identifies a Critical Role for Zinc in Mineralization for Kidney Stone Disease","volume":"10","author":"T Chi","year":"2015","journal-title":"PLoS ONE"},{"issue":"1","key":"ref47","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3945\/an.112.003038","article-title":"Zinc biochemistry: from a single zinc enzyme to a key element of life","volume":"4","author":"W Maret","year":"2013","journal-title":"Advances in Nutrition: An International Review Journal"},{"issue":"1","key":"ref48","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s00726-009-0242-y","article-title":"Proteomic analysis reveals altered expression of proteins related to glutathione metabolism and apoptosis in the small intestine of zinc oxide-supplemented piglets","volume":"37","author":"X Wang","year":"2009","journal-title":"Amino Acids"},{"issue":"1","key":"ref49","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.brainres.2006.03.063","article-title":"Age-related changes in glutathione and glutathione-related enzymes in rat brain","volume":"1090","author":"Y Zhu","year":"2006","journal-title":"Brain Research"},{"issue":"4","key":"ref50","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1111\/jpn.12122","article-title":"Effects of sodium butyrate on growth performance, haematological and immunological characteristics of weanling piglets","volume":"98","author":"C Fang","year":"2014","journal-title":"Journal of Animal Physiology and Animal Nutrition"},{"issue":"1","key":"ref51","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1159\/000171432","article-title":"Diamine Oxidase: An Overview of Historical, Biochemical and Functional Aspects","volume":"12","author":"MCJ Wolvekamp","year":"1994","journal-title":"Digestive Diseases"},{"issue":"1","key":"ref52","first-page":"108","article-title":"Effects of montmorillonite\u2013zinc oxide hybrid on performance, diarrhea, intestinal permeability and morphology of weanling pigs","volume":"177","author":"CH Hu","year":"2012","journal-title":"Animal Feed Science and Technology"},{"issue":"12","key":"ref53","doi-asserted-by":"crossref","first-page":"4077","DOI":"10.1093\/jn\/133.12.4077","article-title":"Zinc Oxide Protects Cultured Enterocytes from the Damage Induced by Escherichia coli","volume":"133","author":"M Roselli","year":"2003","journal-title":"Journal of Nutrition"},{"issue":"3","key":"ref54","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.2527\/jas.2012-5796","article-title":"Early weaning increases intestinal permeability, alters expression of cytokine and tight junction proteins, and activates mitogen-activated protein kinases in pigs","volume":"91","author":"CH Hu","year":"2013","journal-title":"Journal of Animal Science"},{"issue":"3","key":"ref55","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1093\/jn\/129.3.613","article-title":"Weaning Anorexia May Contribute to Local Inflammation in the Piglet Small Intestine","volume":"129","author":"BA Mccracken","year":"1999","journal-title":"Journal of Nutrition"},{"issue":"3","key":"ref56","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1093\/jn\/134.3.641","article-title":"Weaning is associated with an upregulation of expression of inflammatory cytokines in the intestine of piglets","volume":"134","author":"S Pie","year":"2004","journal-title":"Journal of Nutrition"},{"issue":"1","key":"ref57","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.anifeedsci.2011.12.022","article-title":"Nutrition and pathology of weaner pigs: Nutritional strategies to support barrier function in the gastrointestinal tract","volume":"173","author":"JC Kim","year":"2012","journal-title":"Animal Feed Science and Technology"},{"issue":"04","key":"ref58","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1017\/S0007114512005508","article-title":"Diosmectite\u2013zinc oxide composite improves intestinal barrier function, modulates expression of pro-inflammatory cytokines and tight junction protein in early weaned pigs","volume":"110","author":"C Hu","year":"2013","journal-title":"British Journal of Nutrition"},{"issue":"1","key":"ref59","first-page":"65","article-title":"Effects of zinc oxide supported on zeolite on growth performance, intestinal microflora and permeability, and cytokines expression of weaned pigs","volume":"181","author":"CH Hu","year":"2013","journal-title":"Animal Feed Science and Technology"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1159\/000204103","article-title":"Intestinal Expression of TFF and Related Genes During Postnatal Development in a Piglet Probiotic Trial","volume":"23","author":"J Scholven","year":"2009","journal-title":"Cellular Physiology and Biochemistry"},{"issue":"3","key":"ref61","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1177\/1753425916632303","article-title":"L-Cysteine protects intestinal integrity, attenuates intestinal inflammation and oxidant stress, and modulates NF-\u03baB and Nrf2 pathways in weaned piglets after LPS challenge","volume":"22","author":"ZH Song","year":"2016","journal-title":"Innate Immunity"},{"issue":"2","key":"ref62","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1159\/000014146","article-title":"Expression of Intestinal Trefoil Factor in Developing Rat Intestine","volume":"76","author":"J Lin","year":"1999","journal-title":"Neonatology"},{"issue":"4","key":"ref63","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1007\/s00726-012-1230-1","article-title":"Induction of NAD (P) H: quinone oxidoreductase 1 expression by cysteine via Nrf2 activation in human intestinal epithelial LS180 cells","volume":"43","author":"H Satsu","year":"2012","journal-title":"Amino Acids"}],"updated-by":[{"DOI":"10.1371\/journal.pone.0188587","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2017,11,17]],"date-time":"2017-11-17T00:00:00Z","timestamp":1510876800000}}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0182550","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T04:27:46Z","timestamp":1589776066000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0182550"}},"subtitle":[],"editor":[{"given":"Yogendra Kumar","family":"Mishra","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2017,8,8]]},"references-count":63,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2017,8,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0182550","relation":{"correction":[{"id-type":"doi","id":"10.1371\/journal.pone.0188587","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,8]]}}}