{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T09:01:36Z","timestamp":1792573296580,"version":"4.5.0"},"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T00:00:00Z","timestamp":1503532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0183157","type":"journal-article","created":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T17:42:26Z","timestamp":1503596546000},"page":"e0183157","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":49,"title":["Age- and severity-adjusted treatment of proximal humerus fractures in children and adolescents\u2014A systematical review and meta-analysis"],"prefix":"10.1371","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1112-8291","authenticated-orcid":true,"given":"Lisa","family":"Hohloch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helge","family":"Eberbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinand C.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3359-2669","authenticated-orcid":true,"given":"Peter C.","family":"Strohm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kilian","family":"Reising","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5913-624X","authenticated-orcid":true,"given":"Norbert P.","family":"S\u00fcdkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8755-6383","authenticated-orcid":true,"given":"J\u00f6rn","family":"Zwingmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,8,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3109\/17453679008993512","article-title":"Fractures of the proximal humerus in children. Nine-year follow-up of 64 unoperated on cases","volume":"61","author":"CF Larsen","year":"1990","journal-title":"Acta Orthop Scand"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1302\/0301-620X.68B4.3733832","article-title":"Fractures of the proximal humeral epiphysis. Their influence on humeral growth","volume":"68","author":"MP Baxter","year":"1986","journal-title":"J Bone Joint Surg Br"},{"key":"ref3","first-page":"24","article-title":"Fractures of the proximal humeral epiphysial plate","volume":"41","author":"CS Neer 2nd","year":"1965","journal-title":"Clin Orthop Relat Res"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/01.blo.0000156005.01503.43<","article-title":"Pediatric shoulder trauma","author":"JY Bishop","year":"2005","journal-title":"Clin Orthop Relat Res"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"289","DOI":"10.2106\/00004623-196951020-00008","article-title":"Fractures involving the proximal humeral epiphyseal plate","volume":"51","author":"TB Dameron Jr.","year":"1969","journal-title":"J Bone Joint Surg Am"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1055\/s-2004-815781","article-title":"Displaced fractures of the proximal humerus in children require open\/closed reduction and internal fixation","volume":"14","author":"E Schwendenwein","year":"2004","journal-title":"Eur J Pediatr Surg"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/01241398-200303000-00015","article-title":"Severely displaced proximal humeral epiphyseal fractures","volume":"23","author":"MB Dobbs","year":"2003","journal-title":"J Pediatr Orthop"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/BF00195216","article-title":"Fractures of the proximal humeral epiphysis","volume":"17","author":"J Burgos-Flores","year":"1993","journal-title":"Int Orthop"},{"key":"ref9","first-page":"280","article-title":"Late results of sub-capital humerus fracture in children","volume":"44","author":"C Frey","year":"1989","journal-title":"Z Kinderchir"},{"key":"ref10","first-page":"383","article-title":"Closed flexible medullary nailing in pediatric traumatology","volume":"24","author":"JN Ligier","year":"1983","journal-title":"Chir Pediatr"},{"key":"ref11","first-page":"527","article-title":"Surgical treatment of fractures of the long bones in children. Interference between osteosynthesis and the physiological processes of consolidation. Therapeutic indications","volume":"121","author":"JP Metaizeau","year":"1984","journal-title":"J Chir (Paris)"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s00590-013-1177-2","article-title":"Functional results of displaced proximal humerus fractures in children treated by elastic stable intramedullary nail","volume":"24","author":"A Khan","year":"2014","journal-title":"Eur J Orthop Surg Traumatol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/BPB.0000000000000009","article-title":"Evaluation of upper-extremity function following surgical treatment of displaced proximal humerus fractures in children","volume":"23","author":"F Canavese","year":"2014","journal-title":"J Pediatr Orthop B"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s00264-013-2122-z","article-title":"Closed\/open reduction and titanium elastic nails for severely displaced proximal humeral fractures in children","volume":"38","author":"X Wang","year":"2014","journal-title":"Int Orthop"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1097\/BPO.0b013e3182306860","article-title":"Minimally invasive treatment for severely displaced proximal humeral fractures in children using titanium elastic nails","volume":"31","author":"F Xie","year":"2011","journal-title":"J Pediatr Orthop"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/j.injury.2008.04.001","article-title":"Treatment of severely displaced proximal humeral fractures in children with retrograde elastic stable intramedullary nailing","volume":"39","author":"FF Fernandez","year":"2008","journal-title":"Injury"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/01202412-200601000-00010","article-title":"Treatment of severely displaced proximal humeral fractures in children with elastic stable intramedullary nailing","volume":"15","author":"Y Chee","year":"2006","journal-title":"J Pediatr Orthop B"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s11832-011-0328-4","article-title":"Proximal humerus fractures in the pediatric population: a systematic review","volume":"5","author":"S Pahlavan","year":"2011","journal-title":"J Child Orthop"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"77","DOI":"10.5435\/JAAOS-D-14-00033","article-title":"Evaluation and management of pediatric proximal humerus fractures","volume":"23","author":"CA Popkin","year":"2015","journal-title":"J Am Acad Orthop Surg"},{"key":"ref20","first-page":"369","article-title":"Fractures of the proximal humerus and shaft in children","volume":"41","author":"JH Beaty","year":"1992","journal-title":"Instr Course Lect"},{"key":"ref21","unstructured":"Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften. S1-Leitlinie 006\/040: Leitlinien der deutschen Gesellschaft f\u00fcr Kinderchirurgie. Proximale Humerusfraktur beim Kind. 2016. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.awmf.org\/uploads\/tx_szleitlinien\/006-040l_S1_proximale_Humerusfrakltur__2016-05.pdf\" xlink:type=\"simple\">http:\/\/www.awmf.org\/uploads\/tx_szleitlinien\/006-040l_S1_proximale_Humerusfrakltur__2016-05.pdf<\/ext-link>"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.jclinepi.2009.06.005","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"62","author":"D Moher","year":"2009","journal-title":"J Clin Epidemiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1034\/j.1600-0838.2000.010001002.x","article-title":"Studies of surgical outcome after patellar tendinopathy: clinical significance of methodological deficiencies and guidelines for future studies. Victorian Institute of Sport Tendon Study Group","volume":"10","author":"BD Coleman","year":"2000","journal-title":"Scand J Med Sci Sports"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/j.injury.2013.04.003","article-title":"Clinical results after different operative treatment methods of radial head and neck fractures: a systematic review and meta-analysis of clinical outcome","volume":"44","author":"J Zwingmann","year":"2013","journal-title":"Injury"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1007\/s00402-013-1788-4","article-title":"Malposition and revision rates of different imaging modalities for percutaneous iliosacral screw fixation following pelvic fractures: a systematic review and meta-analysis","volume":"133","author":"J Zwingmann","year":"2013","journal-title":"Arch Orthop Trauma Surg"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1097\/BPO.0000000000000265","article-title":"Operative versus nonoperative treatment of displaced proximal humeral physeal fractures: a matched cohort","volume":"35","author":"GW Chaus","year":"2015","journal-title":"J Pediatr Orthop"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1016\/j.jse.2014.01.015","article-title":"Elastic stable intramedullary nailing versus Kirschner wire pinning: outcome of severely displaced proximal humeral fractures in juvenile patients","volume":"23","author":"T Kraus","year":"2014","journal-title":"J Shoulder Elbow Surg"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1097\/BPO.0b013e31819bd9a7","article-title":"Proximal humeral fractures in children and adolescents","volume":"29","author":"C Bahrs","year":"2009","journal-title":"J Pediatr Orthop"},{"key":"ref29","first-page":"406","article-title":"Injuries of the proximal humeral epiphysis. Indications for surgical therapy and results","volume":"54","author":"G Giebel","year":"1983","journal-title":"Chirurg"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1097\/00005131-200309000-00007","article-title":"Treatment of displaced, proximal, humeral, epiphyseal fractures with a two-prong splint","volume":"17","author":"V Karatosun","year":"2003","journal-title":"J Orthop Trauma"},{"key":"ref31","first-page":"433","article-title":"Fracture of the upper end of the humerus in children. A follow-up of 44 cases","volume":"130","author":"S Nilsson","year":"1965","journal-title":"Acta Chir Scand"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/01.blo.0000156452.91271.fb","article-title":"Pediatric fractures of the humerus","author":"H Caviglia","year":"2005","journal-title":"Clin Orthop Relat Res"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0183157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T19:08:33Z","timestamp":1659380913000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0183157"}},"subtitle":[],"editor":[{"given":"Martijn","family":"van Griensven","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,8,24]]},"references-count":32,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2017,8,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0183157","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,24]]}}}