{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T08:05:13Z","timestamp":1790928313683,"version":"4.1.0"},"reference-count":43,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T00:00:00Z","timestamp":1502668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0183183","type":"journal-article","created":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T23:30:10Z","timestamp":1502753410000},"page":"e0183183","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":21,"title":["Risk of cancer in patients with genital warts: A nationwide, population-based cohort study in Taiwan"],"prefix":"10.1371","volume":"12","author":[{"given":"Ching-Yi","family":"Cho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Cheng","family":"Lo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao-Chiu","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chou-Cheng","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Jen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7416-0371","authenticated-orcid":true,"given":"Keh-Gong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,8,14]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1128\/JCM.31.10.2667-2673.1993","article-title":"Analysis of human papillomavirus types in exophytic condylomata acuminata by hybrid capture and Southern blot techniques","volume":"31","author":"DR Brown","year":"1993","journal-title":"J Clin Microbiol"},{"issue":"6 Suppl 1","key":"ref2","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1097\/01.ogx.0000221010.82943.8c","article-title":"Human papillomavirus: the burden of infection","volume":"61","author":"D Wiley","year":"2006","journal-title":"Obstet Gynecol Surv"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/canjclin.57.1.7","article-title":"American Cancer Society Guideline for human papillomavirus (HPV) vaccine use to prevent cervical cancer and its precursors","volume":"57","author":"D Saslow","year":"2007","journal-title":"CA Cancer J Clin"},{"issue":"5","key":"ref4","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1002\/ijc.2910250509","article-title":"Partial characterization of viral DNA from human genital warts (Condylomata acuminata)","volume":"25","author":"L Gissmann","year":"1980","journal-title":"Int J Cancer"},{"key":"ref5","first-page":"765","article-title":"Cervical cancer. News on papillomaviruses","volume":"1988","author":"DJ McCance","journal-title":"Nature"},{"key":"ref6","first-page":"613","article-title":"Malignant transformation of condyloma acuminatum","volume":"103","author":"A Siegel","year":"1962","journal-title":"Review of the literature and report of a case. Am J Surg"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1093\/ajcp\/61.5.702","article-title":"Malignant transformation of condyloma acuminatum. A light microscopic and ultrastructural study","volume":"61","author":"J Kovi","year":"1974","journal-title":"Am J Clin Pathol"},{"issue":"4","key":"ref8","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/BF00146887","article-title":"Case-control study of risk factors for cervical neoplasia in Denmark. II. Role of sexual activity, reproductive factors, and venereal infections","volume":"3","author":"SK Kjaer","year":"1992","journal-title":"Cancer Causes and Control"},{"issue":"22","key":"ref9","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1093\/jnci\/81.22.1726","article-title":"Anal Cancer Incidence: Genital Warts, Anal Fissure or Fistula, Hemorrhoids, and Smoking","volume":"81","author":"AH Elizabeth","year":"1989","journal-title":"Journal of the National Cancer Institute"},{"issue":"4","key":"ref10","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1097\/00001648-199107000-00004","article-title":"Genital Warts, Other Sexually Transmitted Diseases, and Vulvar Cancer","volume":"2","author":"KJ Sherman","year":"1991","journal-title":"Epidemiology"},{"issue":"1","key":"ref11","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0090-8258(90)90010-I","article-title":"Case-control study of in situ and invasive carcinoma of the vagina","volume":"38","author":"LA Brinton","year":"1990","journal-title":"Gynecologic Oncology"},{"issue":"19","key":"ref12","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1056\/NEJM199711063371904","article-title":"Sexually Transmitted Infection as a Cause of Anal Cancer","volume":"337","author":"M Frisch","year":"1997","journal-title":"N Engl J Med"},{"issue":"suppl 1","key":"ref13","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/j.ypmed.2011.08.001","article-title":"The role of HPV in head and neck cancer and review of the HPV vaccine","volume":"53","author":"G D'Souza","year":"2011","journal-title":"Prev Med"},{"issue":"4","key":"ref14","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1002\/ijc.21892","article-title":"Cancer risk among patients with condylomata acuminata","volume":"119","author":"C Nordenvall","year":"2006","journal-title":"Int J Cancer"},{"issue":"4","key":"ref15","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/BF00146887","article-title":"Case-control study of risk factors for cervical neoplasia in Denmark. II. Role of sexual activity, reproductive factors, and venereal infections","volume":"3","author":"SK Kjaer","year":"1992","journal-title":"Cancer Causes and Control"},{"issue":"4","key":"ref16","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1086\/513966","article-title":"Cervical intraepithelial neoplasia, anogenital cancer, and other cancer types in women after hospitalization for condylomata acuminata","volume":"175","author":"S Friis","year":"1997","journal-title":"J Infect Dis"},{"issue":"6798","key":"ref17","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1136\/bmj.303.6798.341","article-title":"Condylomata acuminata and risk of cancer: an epidemiological study","volume":"303","author":"B Sigurgeirsson","year":"1991","journal-title":"BMJ"},{"issue":"10","key":"ref18","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1093\/infdis\/jis228","article-title":"Genital Warts and Risk of Cancer A Danish Study of Nearly 50 000 Patients With Genital Warts","volume":"205","author":"M Blomberg","year":"2012","journal-title":"Journal of Infectious Diseases"},{"issue":"2","key":"ref19","first-page":"101","article-title":"Human papillomavirus, genital warts, and vaccines","volume":"42","author":"PR Hsueh","year":"2009","journal-title":"J Microbiol Immunol Infect"},{"issue":"5","key":"ref20","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1111\/j.1525-1438.2006.00655.x","article-title":"The distribution and differential risks of human papillomavirus genotypes in cervical preinvasive lesions: a Taiwan Cooperative Oncologic Group Study","volume":"16","author":"CA Chen","year":"2006","journal-title":"International Journal of Gynecological Cancer"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"M60","DOI":"10.1016\/j.vaccine.2008.05.042","article-title":"Epidemiology of Human Papillomavirus Infection and Cervical Cancer and Future Perspectives in Hong Kong, Singapore and Taiwan","volume":"26","author":"SK Tay","year":"2008","journal-title":"Vaccine"},{"key":"ref22","unstructured":"National Health Insurance Administration, Ministry of Health and Welfare, Executive Yuan: National Health Insurance Annual Report in Taiwan (R.O.C.) (2014\u20132015)"},{"issue":"8","key":"ref23","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S1470-2045(10)70017-6","article-title":"HPV-associated head and neck cancer: a virus-related cancer epidemic","volume":"11","author":"S Marur","year":"2012","journal-title":"Lancet Oncol"},{"issue":"S10","key":"ref24","doi-asserted-by":"crossref","first-page":"2901","DOI":"10.1002\/cncr.23745","article-title":"Burden of potentially human papillomavirus-associated cancers of the oropharynx and oral cavity in the US, 1998\u20132003","volume":"113","author":"AB Ryerson","year":"2008","journal-title":"Cancer"},{"key":"ref25","unstructured":"Surveillance, Epidemiology, and End Results (SEER) Program (<ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.seer.cancer.gov\" xlink:type=\"simple\">www.seer.cancer.gov<\/ext-link>). SEER*Stat Database: Incidence-SEER 9 Regs Public- Use, November 2008 Submission (1973\u20132006)\u2014Linked to County Attributes\u2014Total U.S., 1969\u20132003 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released April 2009, based on the November 2008 submission, 2009."},{"issue":"1","key":"ref26","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1258\/jms.2009.009058","article-title":"Perianal conylomas, anal squamous intraepithelial neoplasms and screening: a review of the literature","volume":"17","author":"S-F Oon","year":"2010","journal-title":"Journal of Medical Screening"},{"issue":"2","key":"ref27","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1165\/rcmb.2003-0259OC","article-title":"Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness","volume":"30","author":"SR Clinton","year":"2004","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"10","key":"ref28","doi-asserted-by":"crossref","first-page":"3316","DOI":"10.1128\/JCM.37.10.3316-3322.1999","article-title":"Detection of multiple human papillomavirus types in Condylomata acuminata lesions from otherwise healthy and immunosuppressed patients","volume":"37","author":"DR Brown","year":"1999","journal-title":"J Clin Microbiol"},{"issue":"suppl 7","key":"ref29","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/annonc\/mdq454","article-title":"The role of human papillomavirus infection in head and neck cancers","volume":"21","author":"S Syrjanen","year":"2010","journal-title":"Annals of Oncology"},{"issue":"21","key":"ref30","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1093\/jnci\/90.21.1626","article-title":"Oral cancer risk in relation to sexual history and evidence of human papillomavirus infection","volume":"90","author":"SM Schwartz","year":"1998","journal-title":"Journal of the National Cancer Institute"},{"issue":"3","key":"ref31","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/(SICI)1097-0142(19970201)79:3<595::AID-CNCR24>3.0.CO;2-Y","article-title":"Human papillomavirus (HPV) in head and neck cancer","volume":"79","author":"IB Paz","year":"1997","journal-title":"Cancer"},{"issue":"3","key":"ref32","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/(SICI)1097-0347(199805)20:3<250::AID-HED11>3.0.CO;2-O","article-title":"Human Papillomavirus and head and neck cancer: Epidemiology and molecular biology","volume":"20","author":"RG McKaig","year":"1998","journal-title":"Head & Neck"},{"issue":"8","key":"ref33","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1002\/hed.20573","article-title":"Current topics in the epidemiology of oral cavity and oropharyngeal cancers","volume":"29","author":"ML Gillison","year":"2007","journal-title":"Head & Neck"},{"issue":"12","key":"ref34","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1080\/00016480510043945","article-title":"Strong association between infection with human papillomavirus and oral and oropharyngeal squamous cell carcinoma: A population-based case-control study in southern Sweden","volume":"125","author":"BG Hansson","year":"2005","journal-title":"Acta Otolaryngol"},{"key":"ref35","author":"J Ferlay","year":"2013"},{"issue":"2","key":"ref36","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1002\/ijc.29330","article-title":"Incidence trends of human papillomavirus-related head and neck cancer in Taiwan, 1995\u20132009","volume":"137","author":"TZ Hwang","year":"2015","journal-title":"Int J Cancer"},{"issue":"12","key":"ref37","doi-asserted-by":"crossref","first-page":"2888","DOI":"10.1038\/jid.2008.162","article-title":"Exposure Profiles and Human Papillomavirus Infection in Skin Cancer: An Analysis of 25 Genus \u03b2-Types in a Population-Based Study","volume":"128","author":"AS Patel","year":"2008","journal-title":"Journal of Investigative Dermatology"},{"issue":"6","key":"ref38","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1086\/521031","article-title":"Cutaneous human papillomaviruses found in sun-exposed skin: Beta-papillomavirus species 2 predominates in squamous cell carcinoma","volume":"196","author":"O Forslund","year":"2007","journal-title":"J Infect Dis"},{"issue":"7","key":"ref39","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1038\/sj.bjc.6602475","article-title":"Tobacco smoking, snuff dipping and the risk of cutaneous squamous cell carcinoma: a nationwide cohort study in Sweden","volume":"92","author":"A Odenbro","year":"2005","journal-title":"Br J Cancer"},{"issue":"6","key":"ref40","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1002\/cncr.11191","article-title":"The presence of human papillomavirus type 16\/18 DNA in blood circulation may act as a risk marker of lung cancer in Taiwan","volume":"97","author":"HL Chiou","year":"2003","journal-title":"Cancer"},{"issue":"1","key":"ref41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.kjms.2011.10.027","article-title":"Towards the eradication of hepatitis B in Taiwan","volume":"28","author":"Wait Wusanne","year":"2012","journal-title":"The Kaohsiung J Med Sci"},{"issue":"4","key":"ref42","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jadohealth.2010.01.016","article-title":"Beyond cervical cancer: burden of other HPV- related cancers among men and women","volume":"46","author":"K Anil","year":"2010","journal-title":"J Adolesc Health"},{"issue":"12","key":"ref43","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.jfma.2012.10.004","article-title":"A human papillomavirus public vaccination program in Taiwan: the Kinmen County experience","volume":"111","author":"CC Lee","year":"2012","journal-title":"J Formos Med Assoc"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0183183","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T06:42:06Z","timestamp":1602744126000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0183183"}},"subtitle":[],"editor":[{"given":"Marcia Edilaine Lopes","family":"Consolaro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,8,14]]},"references-count":43,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2017,8,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0183183","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,14]]}}}