{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:01:29Z","timestamp":1790755289430,"version":"4.1.0"},"reference-count":44,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T00:00:00Z","timestamp":1504569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Agence Nationale de la Recherche (FR)","award":["ANR-14-ASMA-0002"],"award-info":[{"award-number":["ANR-14-ASMA-0002"]}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-14-ASMA-0002"],"award-info":[{"award-number":["ANR-14-ASMA-0002"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)","award":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)\u00bb"],"award-info":[{"award-number":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)\u00bb"]}]},{"name":"Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)","award":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)\u00bb"],"award-info":[{"award-number":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)\u00bb"]}]},{"name":"Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)","award":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)\u00bb"],"award-info":[{"award-number":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)\u00bb"]}]},{"name":"Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)","award":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)"],"award-info":[{"award-number":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)"]}]},{"name":"Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)","award":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)"],"award-info":[{"award-number":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)"]}]},{"name":"Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)","award":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)\u00bb"],"award-info":[{"award-number":["Sectoral Scientific Program \u00abProblem-oriented research in the epidemiological surveillance of infectious and parasitic diseases (2016-2020)\u00bb"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0183714","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T17:39:08Z","timestamp":1504633148000},"page":"e0183714","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":39,"title":["Russian isolates enlarge the known geographic diversity of Francisella tularensis subsp. mediasiatica"],"prefix":"10.1371","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9501-1380","authenticated-orcid":true,"given":"Vitalii","family":"Timofeev","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Bakhteeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galina","family":"Titareva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Kopylov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Christiany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Mokrievich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Dyatlov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Vergnaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,9,5]]},"reference":[{"issue":"21","key":"ref1","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1001\/jama.285.21.2763","article-title":"Tularemia as a biological weapon: medical and public health management","volume":"285","author":"DT Dennis","year":"2001","journal-title":"JAMA"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1196\/annals.1409.011","article-title":"Molecular epidemiology, evolution, and ecology of <italic>Francisella<\/italic>","volume":"1105","author":"P Keim","year":"2007","journal-title":"Ann N Y Acad Sci"},{"key":"ref3","first-page":"150","article-title":"Toward an understanding of the perpetuation of the agent of tularemia","volume":"1","author":"SR Telford 3rd","year":"2010","journal-title":"Front Microbiol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3389\/fcimb.2014.00035","article-title":"Comparative review of <italic>Francisella tularensis<\/italic> and <italic>Francisella novicida<\/italic>","volume":"4","author":"LC Kingry","year":"2014","journal-title":"Front Cell Infect Microbiol"},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.5152\/balkanmedj.2014.13117","article-title":"Epidemiology of tularemia","volume":"31","author":"\u015e G\u00fcrcan","year":"2014","journal-title":"Balkan Med J"},{"issue":"12","key":"ref6","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.3201\/eid2112.150634","article-title":"Water as Source of <italic>Francisella tularensis<\/italic> Infection in Humans, Turkey","volume":"21","author":"S Kili\u00e7","year":"2015","journal-title":"Emerging infectious diseases"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"e1000459","DOI":"10.1371\/journal.ppat.1000459","article-title":"Comparative genomic characterization of <italic>Francisella tularensis<\/italic> strains belonging to low and high virulence subspecies","volume":"5","author":"MD Champion","year":"2009","journal-title":"PLoS Pathog"},{"issue":"2","key":"ref8","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1183\/09031936.03.00088903","article-title":"Tularaemia","volume":"21","author":"A T\u00e4rnvik","year":"2003","journal-title":"Eur Respir J"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1146\/annurev.micro.60.080805.142126","article-title":"<italic>Francisella tularensis<\/italic>: taxonomy, genetics, and Immunopathogenesis of a potential agent of biowarfare","volume":"60","author":"MK McLendon","year":"2006","journal-title":"Annu Rev Microbiol"},{"issue":"7","key":"ref10","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1086\/597261","article-title":"Molecular Epidemiology of <italic>Francisella tularensis<\/italic> in the United States","volume":"48","author":"KJ Kugeler","year":"2009","journal-title":"Clin Infect Dis"},{"issue":"12","key":"ref11","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.3201\/eid1412.080435","article-title":"<italic>Francisella novicida<\/italic> bacteremia, Thailand","volume":"14","author":"A Leelaporn","year":"2008","journal-title":"Emerg Infect Dis"},{"issue":"Pt 9","key":"ref12","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1099\/jmm.0.05245-0","article-title":"Characterization of a novicida-like subspecies of <italic>Francisella tularensis<\/italic> isolated in Australia","volume":"52","author":"MJ Whipp","year":"2003","journal-title":"J Med Microbiol"},{"issue":"Pt 8","key":"ref13","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1099\/ijs.0.015941-0","article-title":"Description of <italic>Francisella hispaniensis<\/italic> sp. nov., isolated from human blood, reclassification of <italic>Francisella novicida<\/italic> (Larson et al. 1955) Olsufiev et al. 1959 as <italic>Francisella tularensis<\/italic> subsp. <italic>novicida<\/italic> comb. nov. and emended description of the genus <italic>Francisella<\/italic>","volume":"60","author":"B Huber","year":"2010","journal-title":"Int J Syst Evol Microbiol"},{"issue":"Pt 8","key":"ref14","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1099\/ijs.0.022830-0","article-title":"Objections to the transfer of <italic>Francisella novicida<\/italic> to the subspecies rank of <italic>Francisella tularensis<\/italic>","volume":"60","author":"A Johansson","year":"2010","journal-title":"Int J Syst Evol Microbiol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1186\/1471-2180-9-213","article-title":"Whole genome single nucleotide polymorphism based phylogeny of <italic>Francisella tularensis<\/italic> and its application to the development of a strain typing assay","volume":"9","author":"GA Pandya","year":"2009","journal-title":"BMC Microbiol"},{"issue":"3","key":"ref16","doi-asserted-by":"crossref","DOI":"10.1128\/AEM.02589-16","article-title":"Whole-Genome Relationships among <italic>Francisella<\/italic> Bacteria of Diverse Origins Define New Species and Provide Specific Regions for Detection","volume":"83","author":"JF Challacombe","year":"2017","journal-title":"Appl Environ Microbiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1186\/1756-0500-2-223","article-title":"<italic>Francisella tularensis<\/italic> subsp. <italic>novicida<\/italic> isolated from a human in Arizona","volume":"2","author":"DN Birdsell","year":"2009","journal-title":"BMC Res Notes"},{"issue":"8","key":"ref18","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1128\/JCM.34.8.1995-2000.1996","article-title":"Characterization of two unusual clinically significant <italic>Francisella<\/italic> strains","volume":"34","author":"JE, 3rd Clarridge","year":"1996","journal-title":"J Clin Microbiol"},{"issue":"7","key":"ref19","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1128\/JCM.27.7.1601-1608.1989","article-title":"<italic>Francisella philomiragia<\/italic> comb. nov. (formerly Yersinia philomiragia) and <italic>Francisella tularensis<\/italic> biogroup <italic>novicida<\/italic> (formerly <italic>Francisella novicida<\/italic>) associated with human disease","volume":"27","author":"DG Hollis","year":"1989","journal-title":"J Clin Microbiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1099\/00207713-33-4-872","article-title":"Subspecific taxonomy of Francisella tularensis McCoy and Chapin 1912","volume":"vol. 33","author":"N.G. Olsufjev","year":"1983","journal-title":"Int. J. Syst. Bacteriol"},{"key":"ref21","first-page":"42","article-title":"Taxonomy of the genus <italic>Francisella<\/italic>","volume":"5","author":"MA Aikimbaev","year":"1966","journal-title":"Rep Acad Sci Kaz SSR Ser Biol"},{"issue":"7","key":"ref22","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1128\/JCM.41.7.2924-2931.2003","article-title":"Genome-wide DNA microarray analysis of <italic>Francisella tularensis<\/italic> strains demonstrates extensive genetic conservation within the species but identifies regions that are unique to the highly virulent <italic>F<\/italic>. <italic>tularensis<\/italic> subsp. <italic>tularensis<\/italic>","volume":"41","author":"M Broekhuijsen","year":"2003","journal-title":"J Clin Microbiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1099\/00207713-33-4-872","article-title":"Subspecific taxonomy of Francisella tularensis McCoy and Chapin 1912","volume":"33","author":"N.G. Olsufjev","year":"1983","journal-title":"Int. J. Syst. Bacteriol"},{"key":"ref24","first-page":"66","article-title":"Isolation of Central Asian subspecies of tularemia agent in the Altai territory","volume":"115","author":"AN Mokrievich","year":"2013","journal-title":"Prob Espec Dang Infec"},{"issue":"17","key":"ref25","doi-asserted-by":"crossref","first-page":"5808","DOI":"10.1128\/JB.186.17.5808-5818.2004","article-title":"Worldwide genetic relationships among <italic>Francisella tularensis<\/italic> isolates determined by multiple-locus variable-number tandem repeat analysis","volume":"186","author":"A Johansson","year":"2004","journal-title":"J Bacteriol"},{"key":"ref26","first-page":"42","article-title":"Differentiation of geographic races of <italic>Francisella tularensis<\/italic> on the basis of citrulline ureidase activity","volume":"1","author":"IV Rodionova","year":"1970","journal-title":"Lab Delo"},{"issue":"2","key":"ref27","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1042\/bj1040627","article-title":"A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids","volume":"104","author":"MK Gaitonde","year":"1967","journal-title":"Biochem J"},{"issue":"20","key":"ref28","doi-asserted-by":"crossref","first-page":"3571","DOI":"10.1128\/JB.01359-13","article-title":"FipB, an essential virulence factor of <italic>Francisella tularensis<\/italic> subsp. <italic>tularensis<\/italic>, has dual roles in disulfide bond formation","volume":"196","author":"A Qin","year":"2014","journal-title":"J Bacteriol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/1471-2105-14-148","article-title":"Software for selecting the most informative sets of genomic loci for multi-target microbial typing","volume":"14","author":"MV O'Sullivan","year":"2013","journal-title":"BMC Bioinformatics"},{"issue":"3","key":"ref30","doi-asserted-by":"crossref","first-page":"223","DOI":"10.7883\/yoken.JJID.2008.223","article-title":"Characteristics of the Turkish isolates of <italic>Francisella tularensis<\/italic>","volume":"61","author":"S G\u00fcrcan","year":"2008","journal-title":"Jpn J Infect Dis"},{"issue":"8","key":"ref31","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1128\/JB.01786-08","article-title":"Phylogeography of <italic>Francisella tularensis<\/italic>: global expansion of a highly fit clone","volume":"191","author":"AJ Vogler","year":"2009","journal-title":"J Bacteriol"},{"issue":"22","key":"ref32","doi-asserted-by":"crossref","first-page":"6531","DOI":"10.1093\/nar\/18.22.6531","article-title":"DNA polymorphisms amplified by arbitrary primers are useful as genetic markers","volume":"18","author":"JG Williams","year":"1990","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"ref33","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/ng1499","article-title":"The complete genome sequence of <italic>Francisella tularensis<\/italic>, the causative agent of tularemia","volume":"37","author":"P Larsson","year":"2005","journal-title":"Nat Genet"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1186\/1471-2164-13-268","article-title":"Genome characterisation of the genus Francisella reveals insight into similar evolutionary paths in pathogens of mammals and fish","volume":"13","author":"A Sjodin","year":"2012","journal-title":"BMC Genomics"},{"issue":"2","key":"ref35","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/1462-2920.12052","article-title":"The phylogeographic pattern of <italic>Francisella tularensis<\/italic> in Sweden indicates a Scandinavian origin of Eurosiberian tularaemia","volume":"15","author":"E Karlsson","year":"2013","journal-title":"Environ Microbiol"},{"issue":"2","key":"ref36","doi-asserted-by":"crossref","first-page":"290","DOI":"10.3201\/eid1802.111305","article-title":"Phylogeography of <italic>Francisella tularensis<\/italic> subsp. <italic>holarctica<\/italic>, Europe","volume":"18","author":"M Gyuranecz","year":"2012","journal-title":"Emerging infectious diseases"},{"issue":"1","key":"ref37","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1128\/JCM.30.1.172-175.1992","article-title":"Characterization and classification of strains of <italic>Francisella tularensis<\/italic> isolated in the central Asian focus of the Soviet Union and in Japan","volume":"30","author":"G Sandstr\u00f6m","year":"1992","journal-title":"J Clin Microbiol"},{"key":"ref38","first-page":"200","article-title":"Bergey&apos;s manual of systematic bacteriology","author":"A Sj\u00f6stedt","year":"2005"},{"key":"ref39","first-page":"111","article-title":"Bergey&apos;s manual of systematic bacteriology","volume":"2","author":"A Sj\u00f6stedt","year":"2003"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"32838","DOI":"10.3402\/iee.v6.32838","article-title":"Introduction and persistence of tularemia in Bulgaria","volume":"6","author":"K Myrtenn\u00e4s","year":"2016","journal-title":"Infect Ecol Epidemiol"},{"issue":"7","key":"ref41","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.3201\/eid2007.130931","article-title":"Diversity of <italic>Francisella tularensis<\/italic> subsp. <italic>holarctica<\/italic> lineages, China","volume":"20","author":"Y Wang","year":"2014","journal-title":"Emerg Infect Dis"},{"issue":"2","key":"ref42","doi-asserted-by":"crossref","first-page":"e30624","DOI":"10.1371\/journal.pone.0030624","article-title":"<italic>Yersinia pestis<\/italic> lineages in Mongolia","volume":"7","author":"JM Riehm","year":"2012","journal-title":"PLoS One"},{"issue":"6","key":"ref43","doi-asserted-by":"crossref","first-page":"e6000","DOI":"10.1371\/journal.pone.0006000","article-title":"Genotyping and phylogenetic analysis of <italic>Yersinia pestis<\/italic> by MLVA: insights into the worldwide expansion of Central Asia plague foci","volume":"4","author":"Y Li","year":"2009","journal-title":"PLoS One"},{"issue":"2","key":"ref44","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1073\/pnas.1205750110","article-title":"Historical variations in mutation rate in an epidemic pathogen, <italic>Yersinia pestis<\/italic>","volume":"110","author":"Y Cui","year":"2013","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0183714","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T13:17:36Z","timestamp":1692969456000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0183714"}},"subtitle":[],"editor":[{"given":"Ashlesh K.","family":"Murthy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,9,5]]},"references-count":44,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2017,9,5]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0183714","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,5]]}}}