{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T05:07:12Z","timestamp":1774933632769,"version":"3.50.1"},"reference-count":64,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2017,9,26]],"date-time":"2017-09-26T00:00:00Z","timestamp":1506384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["I01-CX001038"],"award-info":[{"award-number":["I01-CX001038"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000957","name":"Alzheimer's Association","doi-asserted-by":"publisher","award":["NIRG-305779"],"award-info":[{"award-number":["NIRG-305779"]}],"id":[{"id":"10.13039\/100000957","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["Veterans Affairs Biorepository"],"award-info":[{"award-number":["Veterans Affairs Biorepository"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]},{"name":"\u2022 Translational Research Center for Traumatic Brain Injury and Stress Disorders (TRACTS) Veterans Affairs Rehabilitation Research and Development Traumatic Brain Injury Center of Excellence","award":["B6796-C"],"award-info":[{"award-number":["B6796-C"]}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["U01NS086659-01"],"award-info":[{"award-number":["U01NS086659-01"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institute of Aging","award":["P30AG13846; supplement 0572063345-5"],"award-info":[{"award-number":["P30AG13846; supplement 0572063345-5"]}]},{"name":"Department of Defense Peer Reviewed Alzheimer's Research Program","award":["DoD-PRARP #13267017"],"award-info":[{"award-number":["DoD-PRARP #13267017"]}]},{"name":"Concussion Legacy Foundation"},{"name":"Andlinger Family Foundation"},{"name":"WWE"},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["1F32NS096803-01"],"award-info":[{"award-number":["1F32NS096803-01"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01AG08122"],"award-info":[{"award-number":["R01AG08122"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0185541","type":"journal-article","created":{"date-parts":[[2017,9,26]],"date-time":"2017-09-26T13:33:38Z","timestamp":1506432818000},"page":"e0185541","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":66,"title":["CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer\u2019s disease"],"prefix":"10.1371","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1257-981X","authenticated-orcid":true,"given":"Jonathan D.","family":"Cherry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thor D.","family":"Stein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yorghos","family":"Tripodis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor E.","family":"Alvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bertrand R.","family":"Huber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhoda","family":"Au","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick T.","family":"Kiernan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel H.","family":"Daneshvar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesse","family":"Mez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Todd M.","family":"Solomon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael L.","family":"Alosco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann C.","family":"McKee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2017,9,26]]},"reference":[{"issue":"10","key":"ref1","doi-asserted-by":"crossref","first-page":"S460","DOI":"10.1016\/j.pmrj.2011.08.008","article-title":"Long-term consequences of repetitive brain trauma: chronic traumatic encephalopathy","volume":"3","author":"RA Stern","year":"2011","journal-title":"PM R"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s00401-013-1230-6","article-title":"The neuropathology of sport","volume":"127","author":"AC McKee","year":"2014","journal-title":"Acta Neuropathol"},{"issue":"134","key":"ref3","doi-asserted-by":"crossref","first-page":"134ra60","DOI":"10.1126\/scitranslmed.3003716","article-title":"Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model","volume":"4","author":"LE Goldstein","year":"2012","journal-title":"Sci Transl Med"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1001\/jama.2017.8334","article-title":"Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football","volume":"318","author":"J Mez","year":"2017","journal-title":"JAMA"},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00401-015-1515-z","article-title":"The first NINDS\/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy","volume":"131","author":"AC McKee","year":"2015","journal-title":"Acta Neuropathologica"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s40478-016-0382-8","article-title":"Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy","volume":"4","author":"JD Cherry","year":"2016","journal-title":"Acta neuropathologica communications"},{"issue":"9","key":"ref7","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/nrd3505","article-title":"The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics","volume":"10","author":"E Karran","year":"2011","journal-title":"Nat Rev Drug Discov"},{"issue":"1","key":"ref8","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/jnen\/nlv001","article-title":"Characterization of Early Pathological Tau Conformations and Phosphorylation in Chronic Traumatic Encephalopathy","volume":"75","author":"NM Kanaan","year":"2016","journal-title":"J Neuropathol Exp Neurol"},{"issue":"12","key":"ref9","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1172\/JCI6560","article-title":"Fundamental signals that regulate eosinophil homing to the gastrointestinal tract","volume":"103","author":"A Mishra","year":"1999","journal-title":"J Clin Invest"},{"issue":"4","key":"ref10","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/nm0496-449","article-title":"Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia","volume":"2","author":"EA Garcia-Zepeda","year":"1996","journal-title":"Nat Med"},{"issue":"8","key":"ref11","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1172\/JCI5669","article-title":"Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis","volume":"103","author":"JM Spergel","year":"1999","journal-title":"J Clin Invest"},{"issue":"6","key":"ref12","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1073\/pnas.1211270110","article-title":"CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging","volume":"110","author":"K Baruch","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/1742-2094-8-139","article-title":"Brain microvascular pericytes are immunoactive in culture- cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide","volume":"8","author":"A Kovac","year":"2011","journal-title":"J Neuroinflammation"},{"issue":"12","key":"ref14","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.1002\/glia.22892","article-title":"CCL11 enhances excitotoxic neuronal death by producing reactive oxygen species in microglia","volume":"63","author":"B Parajuli","year":"2015","journal-title":"Glia"},{"key":"ref15","first-page":"1083","article-title":"Minocycline and sulforaphane inhibited lipopolysaccharide-mediated retinal microglial activation","volume":"13","author":"LP Yang","year":"2007","journal-title":"Mol Vis"},{"key":"ref16","article-title":"An emerging role for eotaxins in neurodegenerative disease","author":"AK Huber","year":"2016","journal-title":"Clin Immunol"},{"issue":"5","key":"ref17","doi-asserted-by":"crossref","first-page":"e138","DOI":"10.1212\/NXI.0000000000000138","article-title":"CSF cytokine profile distinguishes multifocal motor neuropathy from progressive muscular atrophy","volume":"2","author":"T Furukawa","year":"2015","journal-title":"Neurol Neuroimmunol Neuroinflamm"},{"issue":"17","key":"ref18","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1212\/WNL.0000000000000908","article-title":"Dysregulation of the IL-23\/IL-17 axis and myeloid factors in secondary progressive MS","volume":"83","author":"AK Huber","year":"2014","journal-title":"Neurology"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"RRN1231","DOI":"10.1371\/currents.RRN1231","article-title":"Abnormal peripheral chemokine profile in Huntington's disease","volume":"3","author":"E Wild","year":"2011","journal-title":"PLoS Curr"},{"issue":"7362","key":"ref20","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/nature10357","article-title":"The ageing systemic milieu negatively regulates neurogenesis and cognitive function","volume":"477","author":"SA Villeda","year":"2011","journal-title":"Nature"},{"issue":"6","key":"ref21","doi-asserted-by":"crossref","first-page":"e64971","DOI":"10.1371\/journal.pone.0064971","article-title":"Inflammatory proteins in plasma are associated with severity of Alzheimer's disease","volume":"8","author":"R Leung","year":"2013","journal-title":"PLoS One"},{"issue":"1","key":"ref22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jalz.2011.10.007","article-title":"National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease","volume":"8","author":"BT Hyman","year":"2012","journal-title":"Alzheimer's & dementia: the journal of the Alzheimer's Association"},{"issue":"1","key":"ref23","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s13195-015-0148-8","article-title":"Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study","volume":"7","author":"J Mez","year":"2015","journal-title":"Alzheimers Res Ther"},{"issue":"6","key":"ref24","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/01.HTR.0000300227.67748.77","article-title":"Initial reliability and validity of the Ohio State University TBI identification method","volume":"22","author":"JD Corrigan","year":"2007","journal-title":"The Journal of head trauma rehabilitation"},{"issue":"14","key":"ref25","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1089\/neu.2012.2690","article-title":"Profile of self-reported problems with executive functioning in college and professional football players","volume":"30","author":"DR Seichepine","year":"2013","journal-title":"Journal of neurotrauma"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"99","DOI":"10.2147\/OAJSM.S58005","article-title":"Self-reported concussion history: impact of providing a definition of concussion","volume":"5","author":"CA Robbins","year":"2014","journal-title":"Open access journal of sports medicine"},{"issue":"1","key":"ref27","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/00005072-199501000-00006","article-title":"An improved approach to prepare human brains for research","volume":"54","author":"JPG Vonsattel","year":"1995","journal-title":"Journal of Neuropathology & Experimental Neurology"},{"issue":"5","key":"ref28","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s00401-007-0311-9","article-title":"Twenty-first century brain banking. Processing brains for research: the Columbia University methods","volume":"115","author":"JPG Vonsattel","year":"2008","journal-title":"Acta neuropathologica"},{"issue":"7","key":"ref29","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1097\/NEN.0b013e3181a9d503","article-title":"Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury","volume":"68","author":"AC McKee","year":"2009","journal-title":"J Neuropathol Exp Neurol"},{"issue":"11","key":"ref30","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1097\/00005072-199911000-00004","article-title":"Application of the National Institute on Aging (NIA)-Reagan Institute criteria for the neuropathological diagnosis of Alzheimer disease","volume":"58","author":"KL Newell","year":"1999","journal-title":"Journal of Neuropathology & Experimental Neurology"},{"issue":"1","key":"ref31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00401-011-0910-3","article-title":"National Institute on Aging\u2013Alzheimer\u2019s Association guidelines for the neuropathologic assessment of Alzheimer\u2019s disease: a practical approach","volume":"123","author":"TJ Montine","year":"2012","journal-title":"Acta neuropathologica"},{"issue":"3","key":"ref32","doi-asserted-by":"crossref","first-page":"417","DOI":"10.3233\/JAD-2006-9S347","article-title":"Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop","volume":"9","author":"IG McKeith","year":"2006","journal-title":"Journal of Alzheimer's Disease"},{"issue":"1","key":"ref33","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00401-007-0237-2","article-title":"Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration","volume":"114","author":"NJ Cairns","year":"2007","journal-title":"Acta neuropathologica"},{"issue":"1","key":"ref34","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/00005072-199601000-00010","article-title":"Validity and reliability of the preliminary NINDS neuropathologic criteria for progressive supranuclear palsy and related disorders","volume":"55","author":"I Litvan","year":"1996","journal-title":"Journal of Neuropathology & Experimental Neurology"},{"issue":"1","key":"ref35","first-page":"1","article-title":"Neuropathology of non-Alzheimer degenerative disorders","volume":"3","author":"DW Dickson","year":"2009","journal-title":"Int J Clin Exp Pathol"},{"issue":"7","key":"ref36","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1097\/NEN.0b013e31817d751c","article-title":"Update on recent molecular and genetic advances in frontotemporal lobar degeneration","volume":"67","author":"EH Bigio","year":"2008","journal-title":"Journal of Neuropathology & Experimental Neurology"},{"issue":"1","key":"ref37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00401-009-0612-2","article-title":"Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update","volume":"119","author":"IR Mackenzie","year":"2010","journal-title":"Acta neuropathologica"},{"issue":"3","key":"ref38","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1136\/jnnp.33.3.338","article-title":"The central nervous system in motor neurone disease","volume":"33","author":"B Brownell","year":"1970","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"key":"ref39","article-title":"Greenfield's Neuropathology, 2-Volume Set","author":"S Love","year":"2008"},{"issue":"Pt 1","key":"ref40","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/brain\/aws307","article-title":"The spectrum of disease in chronic traumatic encephalopathy","volume":"136","author":"AC McKee","year":"2013","journal-title":"Brain"},{"issue":"1","key":"ref41","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00401-015-1515-z","article-title":"The first NINDS\/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy","volume":"131","author":"AC McKee","year":"2016","journal-title":"Acta neuropathologica"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s40478-015-0209-z","article-title":"Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging","volume":"3","author":"AD Bachstetter","year":"2015","journal-title":"Acta neuropathologica communications"},{"issue":"10","key":"ref43","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1001\/jamaneurol.2015.1616","article-title":"Blood-Borne Revitalization of the Aged Brain","volume":"72","author":"JM Castellano","year":"2015","journal-title":"JAMA Neurol"},{"issue":"7628","key":"ref44","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1038\/nature20411","article-title":"Ageing, neurodegeneration and brain rejuvenation","volume":"539","author":"T Wyss-Coray","year":"2016","journal-title":"Nature"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2147\/CLEP.S37929","article-title":"Clinical epidemiology of Alzheimer's disease: assessing sex and gender differences","volume":"6","author":"MM Mielke","year":"2014","journal-title":"Clinical epidemiology"},{"issue":"13","key":"ref46","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1212\/WNL.0b013e3182a55f7f","article-title":"Clinical presentation of chronic traumatic encephalopathy","volume":"81","author":"RA Stern","year":"2013","journal-title":"Neurology"},{"issue":"1","key":"ref47","doi-asserted-by":"crossref","first-page":"e30525","DOI":"10.1371\/journal.pone.0030525","article-title":"CCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimer's disease","volume":"7","author":"K Westin","year":"2012","journal-title":"PLoS One"},{"key":"ref48","article-title":"IFN-gamma and TNF-alpha Are Involved During Alzheimer Disease Progression and Correlate with Nitric Oxide Production: A Study in Algerian Patients","author":"M Belkhelfa","year":"2014","journal-title":"J Interferon Cytokine Res"},{"issue":"9","key":"ref49","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1038\/jcbfm.2009.71","article-title":"The role of the choroid plexus in neutrophil invasion after traumatic brain injury","volume":"29","author":"J Szmydynger-Chodobska","year":"2009","journal-title":"J Cereb Blood Flow Metab"},{"issue":"1","key":"ref50","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/jcbfm.2011.111","article-title":"Posttraumatic invasion of monocytes across the blood-cerebrospinal fluid barrier","volume":"32","author":"J Szmydynger-Chodobska","year":"2012","journal-title":"J Cereb Blood Flow Metab"},{"issue":"1","key":"ref51","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/1742-2094-11-98","article-title":"Neuroinflammation and M2 microglia: the good, the bad, and the inflamed","volume":"11","author":"JD Cherry","year":"2014","journal-title":"J Neuroinflammation"},{"issue":"1\u20132","key":"ref52","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S0165-5728(03)00009-2","article-title":"Regulation of chemokine receptor expression in human microglia and astrocytes","volume":"136","author":"G Flynn","year":"2003","journal-title":"Journal of Neuroimmunology"},{"key":"ref53","article-title":"Targeting CCR3 to Reduce Amyloid-beta Production, Tau Hyperphosphorylation, and Synaptic Loss in a Mouse Model of Alzheimer's Disease","author":"C Zhu","year":"2016","journal-title":"Mol Neurobiol"},{"issue":"3","key":"ref54","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1006\/exmp.2000.2336","article-title":"Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia","volume":"69","author":"P van der Meer","year":"2000","journal-title":"Exp Mol Pathol"},{"issue":"11","key":"ref55","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.3174\/ajnr.A3395","article-title":"A decade of DTI in traumatic brain injury: 10 years and 100 articles later","volume":"34","author":"MB Hulkower","year":"2013","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.arr.2015.12.010","article-title":"Advances in the development of tau PET radiotracers and their clinical applications","volume":"30","author":"N Okamura","year":"2016","journal-title":"Ageing Res Rev"},{"issue":"4","key":"ref57","article-title":"Fluid Biomarkers of Traumatic Brain Injury and Intended Context of Use","volume":"6","author":"T Bogoslovsky","year":"2016","journal-title":"Diagnostics (Basel)"},{"issue":"4","key":"ref58","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.3233\/JAD-151028","article-title":"Preliminary Study of Plasma Exosomal Tau as a Potential Biomarker for Chronic Traumatic Encephalopathy","volume":"51","author":"RA Stern","year":"2016","journal-title":"J Alzheimers Dis"},{"issue":"6","key":"ref59","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1001\/jamaneurol.2014.367","article-title":"Blood biomarkers for brain injury in concussed professional ice hockey players","volume":"71","author":"P Shahim","year":"2014","journal-title":"JAMA Neurol"},{"issue":"10","key":"ref60","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1001\/jamaneurol.2015.1383","article-title":"Peripheral Total Tau in Military Personnel Who Sustain Traumatic Brain Injuries During Deployment","volume":"72","author":"A Olivera","year":"2015","journal-title":"JAMA Neurol"},{"issue":"6140","key":"ref61","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1126\/science.1240514","article-title":"Neuroscience. Garbage truck of the brain","volume":"340","author":"M Nedergaard","year":"2013","journal-title":"Science"},{"key":"ref62","article-title":"Neurofilament Protein and Antineurofilament Antibodies Following Traumatic Brain Injury-Reply","author":"P Shahim","year":"2017","journal-title":"JAMA Neurol"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"16084","DOI":"10.1038\/nrdp.2016.84","article-title":"Traumatic brain injuries","volume":"2","author":"K Blennow","year":"2016","journal-title":"Nat Rev Dis Primers"},{"issue":"1","key":"ref64","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00401-015-1435-y","article-title":"Beta-amyloid deposition in chronic traumatic encephalopathy","volume":"130","author":"TD Stein","year":"2015","journal-title":"Acta Neuropathol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0185541","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T20:16:09Z","timestamp":1570133769000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0185541"}},"subtitle":[],"editor":[{"given":"Stephen D","family":"Ginsberg","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2017,9,26]]},"references-count":64,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2017,9,26]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0185541","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,26]]}}}