{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:50:46Z","timestamp":1784940646683,"version":"3.55.0"},"reference-count":89,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2017,10,6]],"date-time":"2017-10-06T00:00:00Z","timestamp":1507248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Erasmus + Programme of the European Union","award":["2013-0040"],"award-info":[{"award-number":["2013-0040"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0185645","type":"journal-article","created":{"date-parts":[[2017,10,6]],"date-time":"2017-10-06T17:33:58Z","timestamp":1507311238000},"page":"e0185645","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":92,"title":["Heavy metals exposure levels and their correlation with different clinical forms of fetal growth restriction"],"prefix":"10.1371","volume":"12","author":[{"given":"Sally","family":"Sabra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebba","family":"Malmqvist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Saborit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Gratac\u00f3s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2329-1851","authenticated-orcid":true,"given":"Maria Dolores","family":"Gomez Roig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,10,6]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S0002-9378(00)70513-8","article-title":"Morbidity and mortality among very-low-birth-weight neonates with intrauterine growth restriction. The Vermont Oxford Network","volume":"182","author":"IM Bernstein","year":"2000","journal-title":"Am J Obstet Gynecol"},{"issue":"6","key":"ref2","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1177\/0885066604269663","article-title":"Current concepts in intrauterine growth restriction","volume":"19","author":"D Brodsky","year":"2004","journal-title":"J Intensive Care Med"},{"issue":"6","key":"ref3","doi-asserted-by":"crossref","first-page":"F428","DOI":"10.1136\/adc.2006.112243","article-title":"Small for gestational age infants and sudden infant death syndrome: a confluence of complex conditions","volume":"92","author":"CE Hunt","year":"2007","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"ref4","first-page":"640715","article-title":"Diagnosis and Management of Fetal Growth Restriction","volume":"2011","author":"K Bamfo J","year":"2011","journal-title":"J Pregnancy"},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/2249-4847.128717","article-title":"Predicting Disease Severity of Necrotizing Enterocolitis: How to Identify Infants for Future Novel Therapies","volume":"3","author":"TA Markel","year":"2014","journal-title":"J Clin Neonatol"},{"issue":"4","key":"ref6","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jmu.2012.10.005","article-title":"Sequelae of Fetal Growth Restriction","volume":"20","author":"H Ismail","year":"2012","journal-title":"J Med Ultrasound"},{"issue":"2011","key":"ref7","article-title":"Consequences in Infants That Were Intrauterine Growth Restricted. Review Article","volume":"2011","author":"E Cosmi","year":"2011","journal-title":"J Pregnancy"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3109\/14767058.2012.715006","article-title":"Short-term and long-term sequelae in intrauterine growth retardation (IUGR)","volume":"26","author":"S Longo","year":"2013","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"8663","key":"ref9","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0140-6736(89)90710-1","article-title":"Weight in infancy and death from ischaemic heart disease","volume":"2","author":"DJ Barker","year":"1989","journal-title":"Lancet"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1093\/humrep\/des038","article-title":"DNA methylation changes in whole blood is associated with exposure to the environmental contaminants, mercury, lead, cadmium and bisphenol A, in women undergoing ovarian stimulation for IVF","volume":"27","author":"CW Hanna","year":"2012","journal-title":"Hum Reprod"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"145","DOI":"10.5271\/sjweh.2239","article-title":"Reproductive and developmental toxicity of metals","volume":"11","author":"TW Clarkson","year":"1985","journal-title":"Scand J Work Environ Health"},{"issue":"2","key":"ref12","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.envpol.2007.06.012","article-title":"Human health effects of air pollution","volume":"151","author":"M Kampa","year":"2008","journal-title":"Environ Pollut"},{"issue":"3","key":"ref13","doi-asserted-by":"crossref","first-page":"246","DOI":"10.4103\/0253-7613.81505","article-title":"Heavy metals and living systems: An overview","volume":"43","author":"R Singh","year":"2011","journal-title":"Indian J Pharmacol"},{"key":"ref14","first-page":"133","article-title":"Heavy metal toxicity and the environment","volume":"101","author":"PB Tchounwou","year":"2012","journal-title":"EXS"},{"issue":"8","key":"ref15","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.cppeds.2010.07.002","article-title":"Mercury exposure and children's health","volume":"40","author":"S Bose-O'Reilly","year":"2010","journal-title":"Curr Probl Pediatr Adolesc Health Care"},{"issue":"1","key":"ref16","first-page":"15","article-title":"Neurotoxic Effects and Biomarkers of Lead Exposure: A Review","volume":"24","author":"Sanders Talia","year":"2009","journal-title":"Rev Environ Health"},{"issue":"5","key":"ref17","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3961\/jpmph.14.035","article-title":"Health effects of chronic arsenic exposure","volume":"47","author":"YS Hong","year":"2014","journal-title":"J Prev Med Public Health"},{"issue":"4","key":"ref18","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1515\/REVEH.1999.14.4.211","article-title":"Important considerations in the development of public health advisories for arsenic and arsenic-containing compounds in drinking water","volume":"14","author":"PB Tchounwou","year":"1999","journal-title":"Rev Environ Health"},{"issue":"10","key":"ref19","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0278-6915(00)00077-6","article-title":"Pubertal and postpubertal cadmium exposure differentially affects the hypothalamic-pituitary-testicular axis function in the rat","volume":"38","author":"A Lafuente","year":"2000","journal-title":"Food Chem Toxicol"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.toxlet.2009.10.018","article-title":"Accumulation of cadmium in human placenta interacts with the transport of micronutrients to the fetus","volume":"192","author":"M Kippler","year":"2010","journal-title":"Toxicol Lett"},{"issue":"9","key":"ref21","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1017\/S1368980013002619","article-title":"Prenatal mercury exposure and infant birth weight in the Norwegian Mother and Child Cohort Study","volume":"17","author":"K Vejrup","year":"2014","journal-title":"Public Health Nutr"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.envpol.2012.12.013","article-title":"The effects of low-level prenatal lead exposure on birth outcomes","volume":"175","author":"X Xie","year":"2013","journal-title":"Environ Pollut"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.envres.2005.11.006","article-title":"Arsenic speciation transported through the placenta from mother mice to their newborn pups","volume":"101","author":"Jina Yaping","year":"2006","journal-title":"Environmental Research"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1093\/toxsci\/kfm162","article-title":"Arsenic exposure in pregnant mice disrupts placental vasculogenesis and causes spontaneous abortion","volume":"99","author":"W He","year":"2007","journal-title":"Toxicol Sci"},{"issue":"6","key":"ref25","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1097\/EDE.0b013e3181f56a0d","article-title":"Arsenic exposure and risk of spontaneous abortion, stillbirth, and infant mortality","volume":"21","author":"A Rahman","year":"2010","journal-title":"Epidemiology"},{"key":"ref26","article-title":"Heavy Metals in Contaminated Soils: A Review of Sources, Chemistry, Risks and Best Available Strategies for Remediation","volume":"2011","author":"Wuana Raymond A","journal-title":"ISRN Ecology"},{"issue":"4","key":"ref27","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/bdrb.20264","article-title":"Zinc and reproduction: effects of zinc deficiency on prenatal and early postnatal development","volume":"89","author":"JY Uriu-Adams","year":"2010","journal-title":"Birth Defects Res B Dev Reprod Toxicol"},{"issue":"3","key":"ref28","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.envres.2005.05.006","article-title":"Maternal and umbilical cord blood levels of mercury, lead, cadmium, and essential trace elements in Arctic Canada","volume":"100","author":"J Butler Walker","year":"2006","journal-title":"Environ Res"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1186\/s13104-016-2092-5","article-title":"Low level lead exposure and pregnancy outcomes in an observational birth cohort study: dose\u2013response relationships","volume":"9","author":"CM Taylor","year":"2016","journal-title":"BMC Res Notes"},{"issue":"2","key":"ref30","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0009-9120(00)00052-7","article-title":"Toxic and essential elements in placentas of Swedish women","volume":"33","author":"K Osman","year":"2000","journal-title":"Clin Biochem"},{"issue":"5","key":"ref31","doi-asserted-by":"crossref","first-page":"4481","DOI":"10.3390\/ijerph120504481","article-title":"Concentration of Lead, Mercury, Cadmium, Aluminum, Arsenic and Manganese in Umbilical Cord Blood of Jamaican Newborns","volume":"12","author":"MH Rahbar","year":"2015","journal-title":"Int J Environ Res Public Health"},{"issue":"9","key":"ref32","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s10654-009-9370-7","article-title":"The Mothers and Children\u2019s Environmental Health (MOCEH) study. The MOCEH Study Group","volume":"24","author":"BM Kim","year":"2009","journal-title":"Eur J Epidemiol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.envres.2016.10.014","article-title":"The association of lead exposure during pregnancy and childhood anthropometry in the Mexican PROGRESS cohort","volume":"152","author":"S Renzetti","year":"2017","journal-title":"Environ Res"},{"issue":"9","key":"ref34","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1081\/ESE-200026331","article-title":"Effect of Environmental Exposure to Cadmium on Pregnancy Outcome and Fetal Growth: A Study on Healthy Pregnant Women in China","volume":"39","author":"YL Zhang","year":"2004","journal-title":"J Environ Sci Health a Tox Hazard Subst Environ Eng"},{"issue":"10","key":"ref35","doi-asserted-by":"crossref","first-page":"e109984","DOI":"10.1371\/journal.pone.0109984","article-title":"Fetal Exposure to Environmental Neurotoxins in Taiwan","volume":"9","author":"CB Jiang","year":"2014","journal-title":"PLoS One"},{"issue":"9","key":"ref36","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1136\/oem.2010.059758","article-title":"Does prenatal cadmium exposure affect fetal and child growth?","volume":"68","author":"CM Lin","year":"2011","journal-title":"Occup Environ Med"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1159\/000357592","article-title":"Update on the Diagnosis and Classification of Fetal Growth Restriction and Proposal of a Stage-Based Management Protocol","volume":"36","author":"F Figueras","year":"2014","journal-title":"Fetal Diagn Ther"},{"issue":"2","key":"ref38","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S1701-2163(15)30664-2","article-title":"Determination of gestational age by ultrasound","volume":"36","author":"K Butt","year":"2014","journal-title":"J Obstet Gynaecol Can"},{"issue":"1","key":"ref39","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.ejogrb.2006.12.015","article-title":"Customized birthweight standards for a Spanish population","volume":"136","author":"F Figueras","year":"2008","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"2","key":"ref40","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0946-672X(96)80018-6","article-title":"Sample Collection Guidelines for Trace Elements in Blood and Urine","volume":"10","author":"R Cornelis","year":"1996","journal-title":"J Trace Elem Med Biol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1039\/B204532J","article-title":"Enhanced sensitivity in inductively coupled plasma sector field mass spectrometry for direct solid analysis using laser ablation (LA-ICP-SFMS)","volume":"17","author":"C Latkoczy","year":"2002","journal-title":"J. Anal. At. Spectrom."},{"issue":"1\u20133","key":"ref42","first-page":"236","article-title":"Placental transfer of lead, mercury, cadmium, and carbon monoxide in women. III. Factors influencing the accumulation of heavy metals in the placenta and the relationship between metal concentration in the placenta and in maternal and cord blood","volume":"16","author":"H Roels","year":"1978","journal-title":"Environ Res"},{"issue":"2","key":"ref43","first-page":"141","article-title":"Blood and placental concentrations of cadmium, lead, and mercury in mothers and their newborns","volume":"33","author":"P Truska","year":"1989","journal-title":"J Hyg Epidemiol Microbiol Immunol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10354-012-0074-3","article-title":"The role of the placenta in fetal exposure to heavy metals","volume":"162","author":"C Gundacker","year":"2012","journal-title":"Wien. Med. Wochenschr"},{"key":"ref45","first-page":"2198","article-title":"Heavy metals and placental fetal-maternal barrier: A mini-review on the major concerns","volume":"17","author":"D Caserta","year":"2013","journal-title":"Eur. Rev. Med. Pharmacol. Sci"},{"issue":"2","key":"ref46","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0300-483X(93)90124-B","article-title":"Environmental exposure to cadmium and human birthweight","volume":"79","author":"N Frery","year":"1993","journal-title":"Toxicology"},{"issue":"3","key":"ref47","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1021\/es1019614","article-title":"Partition of environmental chemicals between maternal and fetal blood and tissues","volume":"45","author":"LL Needham","year":"2011","journal-title":"Environ Sci Technol"},{"issue":"2","key":"ref48","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ijheh.2010.10.001","article-title":"Heavy metals (lead, cadmium and mercury) in maternal, cord blood and placenta of healthy women","volume":"214","author":"I Al-Saleh","year":"2011","journal-title":"Int J Hyg Environ Health"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1079\/BJN19780079","article-title":"Copper, manganese, zinc, nickel, cadmium and lead in human foetal tissues","volume":"39","author":"Casey Clare E","year":"1978","journal-title":"Br. J. Nutr"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0041-008X(90)90367-4","article-title":"Toxicity of cadmium in the perfused human placenta","volume":"105","author":"PJ Wier","journal-title":"Toxicol. Appl. Pharmacol"},{"issue":"4","key":"ref51","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1039\/C3MT00365E","article-title":"Cadmium concentrations in human blood and urine are associated with polymorphisms in zinc transporter genes","volume":"6","author":"G Rentschler","year":"2014","journal-title":"Metallomics"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.freeradbiomed.2013.08.167","article-title":"Cadmium exposure induces vascular injury due to endothelial oxidative stress: the role of local angiotensin II and COX-2","volume":"65","author":"JK Angeli","year":"2013","journal-title":"Free Radic Biol Med"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/0021-9681(65)90066-4","article-title":"Cadmium as a factor in hypertension","volume":"18","author":"HA Schroeder","year":"1965","journal-title":"J Chronic Dis"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"823","DOI":"10.7326\/0003-4819-98-5-823","article-title":"Trace elements and blood pressure","volume":"98","author":"P Sahman","year":"1983","journal-title":"Ann Intern Med"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1126\/science.6213041","article-title":"Cardiovascular actions of cadmium at environmental exposure levels","volume":"217","author":"S J Kopp","year":"1982","journal-title":"Science"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/bmb\/ldg032","article-title":"Hazards of heavy metal contamination","volume":"68","author":"L J\u00e4rup","year":"2003","journal-title":"Br Med Bull"},{"issue":"1","key":"ref57","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0147-6513(83)90051-9","article-title":"1983. Influence of cadmium on placental structure","volume":"7","author":"JH Peereboom-Stegeman","year":"1983","journal-title":"Ecotoxicol Environ Saf"},{"issue":"2","key":"ref58","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0300-483X(93)90124-B","article-title":"Environmental exposure to cadmium and human birthweight","volume":"79","author":"N Frery","year":"1993","journal-title":"Toxicology"},{"issue":"9","key":"ref59","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1081\/ESE-200026331","article-title":"Effect of environmental exposure to cadmium on pregnancy outcome and fetal growth: a study on healthy pregnant women in China","volume":"39","author":"Y. L. Zhang","year":"2004","journal-title":"J Environ Sci Health A Tox Hazard Subst Environ Eng"},{"issue":"2\u20133","key":"ref60","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.ijheh.2013.04.009","article-title":"Birth outcome measures and maternal exposure to heavy metals (lead, cadmium and mercury) in Saudi Arabian population","volume":"217","author":"I Al-Saleh","year":"2014","journal-title":"Int J Hyg Environ Health"},{"issue":"4","key":"ref61","first-page":"156","article-title":"Effects of smoking and marine diet on birthweight in Greenland","volume":"55","author":"P Bjerregaard","year":"1996","journal-title":"Arctic Med Res"},{"issue":"6","key":"ref62","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1289\/ehp.1104494","article-title":"Evidence on the human health effects of low-level methylmercury exposure","volume":"120","author":"MR Karagas","year":"2012","journal-title":"Environ Health Perspect"},{"issue":"10","key":"ref63","doi-asserted-by":"crossref","first-page":"13482","DOI":"10.3390\/ijerph121013482","article-title":"Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea","volume":"12","author":"YM Kim","year":"2015","journal-title":"Int J Environ Res Public Health"},{"issue":"8","key":"ref64","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1289\/ehp.10831","article-title":"Relation between cord blood mercury levels and early child development in a World Trade Center cohort","volume":"116","author":"SA Lederman","year":"2008","journal-title":"Environ Health Perspect"},{"issue":"9","key":"ref65","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1017\/S1368980013002619","article-title":"Prenatal mercury exposure and infant birth weight in the Norwegian Mother and Child Cohort Study","volume":"17","author":"K Vejrup","year":"2014","journal-title":"Public Health Nutr"},{"issue":"5","key":"ref66","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/jes.2014.26","article-title":"Placental transfer and concentrations of cadmium, mercury, lead, and selenium in mothers, newborns, and young children","volume":"24","author":"Z Chen","year":"2014","journal-title":"J Expo Sci Environ Epidemiol"},{"issue":"3","key":"ref67","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1289\/0900731","article-title":"Interaction between GSTM1\/GSTT1 polymorphism and blood mercury on birth weight","volume":"118","author":"BE Lee","year":"2010","journal-title":"Environ Health Perspect"},{"issue":"1","key":"ref68","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3945\/jn.112.161638","article-title":"Birth weight of Korean infants is affected by the interaction of maternal iron intake and GSTM1 polymorphism","volume":"143","author":"J Hur","year":"2013","journal-title":"J Nutr"},{"issue":"4","key":"ref69","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1136\/oem.2003.012492","article-title":"Factors influencing the difference between maternal and cord blood lead","volume":"62","author":"EW Harville","year":"2005","journal-title":"Occup Environ Med"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10408449509089885","article-title":"Minamata disease: methylmercury poisoning in Japan caused by environmental pollution","volume":"25","author":"M Harada","year":"1995","journal-title":"Crit Rev Toxicol"},{"issue":"2","key":"ref71","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3961\/jpmph.2014.47.2.74","article-title":"Environmental Mercury and Its Toxic Effects","volume":"47","author":"KM Rice","year":"2014","journal-title":"J Prev Med Public Health"},{"issue":"1\u20133","key":"ref72","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0048-9697(99)00444-1","article-title":"Organochlorines and heavy metals in pregnant women from the Disko Bay area in Greenland","volume":"245","author":"P Bjerregaard","year":"2000","journal-title":"Sci Total Environ"},{"issue":"6","key":"ref73","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1093\/ije\/30.6.1272","article-title":"Birthweight in a fishing community: significance of essential fatty acids and marine food contaminants","volume":"30","author":"P Grandjean","year":"2001","journal-title":"Int J Epidemiol"},{"issue":"7","key":"ref74","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/s11745-004-1274-7","article-title":"Gestational age and birth weight in relation to n-3 fatty acids among Inuit (Canada)","volume":"39","author":"M Lucas","year":"2004","journal-title":"Lipids"},{"issue":"3","key":"ref75","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/S1474-4422(13)70278-3","article-title":"Neurobehavioural effects of developmental toxicity","volume":"13","author":"P Grandjean","year":"2014","journal-title":"Lancet Neurol"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"3113","DOI":"10.1016\/j.scitotenv.2010.04.018","article-title":"Monitoring of lead, cadmium, chromium and nickel in placenta from an e-waste recycling town in China","volume":"408","author":"Y Guo","year":"2010","journal-title":"Sci Total Environ"},{"issue":"6","key":"ref77","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s00420-011-0711-y","article-title":"The effects of metallothionein 2A polymorphism on lead metabolism: are pregnant women with a heterozygote genotype for metallothionein 2A polymorphism and their newborns at risk of having higher blood lead levels?","volume":"85","author":"D Tekin","year":"2012","journal-title":"Int Arch Occup Environ Health"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.envres.2015.04.018","article-title":"Metals exposure and risk of small-for-gestational age birth in a Canadian birth cohort: The MIREC study","volume":"140","author":"S Thomas","year":"2015","journal-title":"Environ Res"},{"issue":"3","key":"ref79","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1093\/aje\/kwn332","article-title":"Arsenic exposure during pregnancy and size at birth: a prospective cohort study in Bangladesh","volume":"169","author":"A Rahman","year":"2009","journal-title":"Am J Epidemiol"},{"issue":"4","key":"ref80","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1017\/S2040174414000221","article-title":"Arsenic exposure in early pregnancy alters genome-wide DNA methylation in cord blood, particularly in boys","volume":"5","author":"K Broberg","year":"2014","journal-title":"J Dev Orig Health Dis"},{"issue":"1","key":"ref81","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.reprotox.2008.11.057","article-title":"Fetal growth restriction is related to placental levels of cadmium, lead and arsenic but not with antioxidant activities","volume":"27","author":"MN Llanos","year":"2009","journal-title":"Reprod Toxicol"},{"issue":"1","key":"ref82","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0041-008X(90)90367-4","article-title":"Toxicity of cadmium in the perfused human placenta","volume":"105","author":"PJ Wier","year":"1990","journal-title":"Toxicol Appl Pharmacol"},{"issue":"6","key":"ref83","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0890-6238(01)00174-5","article-title":"Placental cadmium and progesterone concentrations in cigarette smokers","volume":"15","author":"M Piasek","year":"2001","journal-title":"Reprod Toxicol"},{"issue":"5","key":"ref84","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1080\/00039896.1996.9934427","article-title":"Is placenta a good indicator of cadmium and lead exposure?","volume":"51","author":"BI Lagerkvist","year":"1996","journal-title":"Arch Environ Health"},{"issue":"1663","key":"ref85","doi-asserted-by":"crossref","first-page":"20140066","DOI":"10.1098\/rstb.2014.0066","article-title":"The placenta: a multifaceted, transient organ","volume":"370","author":"GJ Burton","year":"2015","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"issue":"8","key":"ref86","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/0002-9378(82)90786-4","article-title":"Cadmium levels in maternal blood, fetal cord blood, and placental tissues of pregnant women who smoke","volume":"142","author":"PM Kuhnert","year":"1982","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"ref87","first-page":"241","article-title":"Cadmium and zinc concentrations in human placentas","volume":"6","author":"J Fiala","year":"1998","journal-title":"Cent Eur J Public Health"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1542\/neo.11-7-e363","article-title":"Neonatology and the Environment: Impact of Early Exposure to Airborne Environmental Toxicants on Infant and Child Neurodevelopment","volume":"11","author":"VA Rauh","year":"2010","journal-title":"Neoreviews"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.envres.2015.04.018","article-title":"Metals exposure and risk of small-for-gestational age birth in a Canadian birth cohort: The MIREC study","volume":"140","author":"S Thomas","year":"2015","journal-title":"Environ Res"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0185645","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T06:36:43Z","timestamp":1589006203000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0185645"}},"subtitle":[],"editor":[{"given":"Rogelio","family":"Cruz-Martinez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,10,6]]},"references-count":89,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2017,10,6]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0185645","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,6]]}}}