{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T21:10:48Z","timestamp":1785273048899,"version":"3.55.0"},"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2017,10,5]],"date-time":"2017-10-05T00:00:00Z","timestamp":1507161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0185960","type":"journal-article","created":{"date-parts":[[2017,10,5]],"date-time":"2017-10-05T13:50:36Z","timestamp":1507211436000},"page":"e0185960","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":10,"title":["Weight loss from 20 years of age is associated with cognitive impairment in middle-aged and elderly individuals"],"prefix":"10.1371","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1480-5777","authenticated-orcid":true,"given":"Kaori","family":"Kitamura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8618-7632","authenticated-orcid":true,"given":"Kazutoshi","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akemi","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ribeka","family":"Takachi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rieko","family":"Oshiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosaku","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiko","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichiro","family":"Tsugane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,10,5]]},"reference":[{"key":"ref1","article-title":"Kokumin-no-Fukushi-to-Kaigo-no-Doko (Trend of Welfare and Care in Japan) 2016\/2017","year":"2016"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1186\/1471-2458-14-643","article-title":"Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis","volume":"14","author":"MA Beydoun","year":"2014","journal-title":"BMC Public Health"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1111\/jgs.12887","article-title":"Milk and dairy consumption and risk of dementia in an elderly Japanese population: the Hisayama Study","volume":"62","author":"M Ozawa","year":"2014","journal-title":"J Am Geriatr Soc"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.jagp.2016.07.009","article-title":"Green Tea Consumption and the Risk of Incident Dementia in Elderly Japanese: The Ohsaki Cohort 2006 Study","volume":"24","author":"Y Tomata","year":"2016","journal-title":"Am J Geriatr Psychiatry"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1093\/ajcn\/83.2.355","article-title":"Green tea consumption and cognitive function: a cross\u2013sectional study from the Tsurugaya Project 1","volume":"83","author":"S Kuriyama","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"e96013","DOI":"10.1371\/journal.pone.0096013","article-title":"Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline","volume":"9","author":"M Noguchi\u2013Shinohara","year":"2014","journal-title":"PLoS One"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3233\/JAD-132225","article-title":"Modifiable lifestyle factors in dementia: a systematic review of longitudinal observational cohort studies","volume":"42","author":"LY Di Marco","year":"2014","journal-title":"J Alzheimers Dis"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"e426","DOI":"10.1111\/j.1467-789X.2010.00825.x","article-title":"Body mass index in midlife and late\u2013life as a risk factor for dementia. a meta\u2013analysis of prospective studies","volume":"12","author":"KJ Anstey","year":"2011","journal-title":"Obes Rev"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1038\/ejcn.2014.199","article-title":"Body mass index in dementia","volume":"68","author":"S Garc\u00eda\u2013Ptacek","year":"2014","journal-title":"Eur J Clin Nutr"},{"issue":"3","key":"ref10","doi-asserted-by":"crossref","first-page":"739","DOI":"10.3233\/JAD-141086","article-title":"2003\u20132013: a decade of body mass index, Alzheimer&apos;s disease, and dementia","volume":"43","author":"TL Emmerzaal","year":"2015","journal-title":"J Alzheimers Dis"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1159\/000447963","article-title":"Modifiable factors associated with cognitive impairment in 1143 Japanese outpatients: The Project in Sado for Total Health (PROST)","volume":"6","author":"K Kitamura","year":"2016","journal-title":"Dement Geriatr Cogn Dis Extra"},{"key":"ref12","unstructured":"Murakami Cohort Study. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.med.niigata-u.ac.jp\/hyg\/project-en.html\" xlink:type=\"simple\">http:\/\/www.med.niigata-u.ac.jp\/hyg\/project-en.html<\/ext-link> Cited 17 March 2017."},{"key":"ref13","doi-asserted-by":"crossref","first-page":"S457","DOI":"10.1097\/00005768-200009001-00004","article-title":"Comparison of three methods for measuring the time spent in physical activity","volume":"32","author":"BE Ainsworth","year":"2000","journal-title":"Med Sci Sports Exerc"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s13340-011-0025-z","article-title":"Validity and applicability of a simple questionnaire for the estimation of total and domain\u2013specific physical activity","volume":"2","author":"H Fujii","year":"2011","journal-title":"Diabetol Int"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/sj.bjc.6602277","article-title":"Impact of alcohol drinking on total cancer risk: data from a large\u2013scale population\u2013based cohort study in Japan","volume":"92","author":"M Inoue","year":"2005","journal-title":"Br J Cancer"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1093\/jjco\/hyu096","article-title":"The JPHC study: design and some findings on the typical Japanese diet","volume":"44","author":"S Tsugane","year":"2014","journal-title":"Jpn J Clin Oncol"},{"key":"ref17","first-page":"189","article-title":"\u2018Mini\u2013mental state\u2019. A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"MF Folstein","year":"1975","journal-title":"J Psychiatr Res"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1159\/000017236","article-title":"The validity of the MMSE and SMQ as screening tests for dementia in the elderly general population: a study of one rural community in Japan","volume":"11","author":"N Maki","year":"2000","journal-title":"Dement Geriatr Cogn Disord"},{"key":"ref19","first-page":"25","article-title":"Screening for Cognitive Impairment in Older Adults: An Evidence Update for the US Preventive Services Task Force","author":"JS Lin","year":"2013"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13195-017-0236-z","article-title":"Increased dementia risk predominantly in diabetes mellitus rather than in hypertension or hyperlipidemia: a population-based cohort study","volume":"9","author":"YC Fan","year":"2017","journal-title":"Alzheimers Res Ther"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1212\/01.wnl.0000176061.33817.90","article-title":"Change in body mass index and risk of incident Alzheimer disease","volume":"65","author":"AS Buchman","year":"2005","journal-title":"Neurology"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S2213-8587(15)00033-9","article-title":"BMI and risk of dementia in two million people over two decades: a retrospective cohort study","volume":"3","author":"N Qizilbash","year":"2015","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1001\/jamaneurol.2015.4756","article-title":"Decline in Weight and Incident Mild Cognitive Impairment: Mayo Clinic Study of Aging","volume":"73","author":"RE Alhurani","year":"2016","journal-title":"JAMA Neurol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1212\/WNL.0b013e318238eec1","article-title":"Alzheimer\u2019s disease neuroimaging initiative: Alzheimer disease biomarkers are associated with body mass index","volume":"77","author":"ED Vidoni","year":"2011","journal-title":"Neurology"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1001\/archneurol.2010.38","article-title":"Reduced lean mass in early Alzheimer disease and its association with brain atrophy","volume":"67","author":"JM Burns","year":"2010","journal-title":"Arch Neurol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1038\/oby.2004.189","article-title":"The implications of body fat mass and fat distribution for cognitive function in elderly women","volume":"12","author":"YZ Bagger","year":"2004","journal-title":"Obes Res"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1093\/ageing\/afv151","article-title":"The risk of overweight\/obesity in mid\u2013life and late life for the development of dementia: a systematic review and meta\u2013analysis of longitudinal studies","volume":"45","author":"E Pedditizi","year":"2016","journal-title":"Age Ageing"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3143\/geriatrics.52.86","article-title":"Prospective study of cognitive decline assessed using the mini-mental state examination and the risk of incident long-term care insurance among community-dwelling older Japanese","volume":"52","author":"Y Taniguchi","year":"2015","journal-title":"Nihon Ronen Igakkai Zasshi"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/1744-9081-6-77","article-title":"Relationship of tooth loss to mild memory impairment and cognitive impairment: findings from the Fujiwara-kyo study","volume":"31","author":"N Okamoto","year":"2010","journal-title":"Behav Brain Funct"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s10654-017-0225-3","article-title":"Alcohol consumption and dementia risk: a dose\u2013response meta\u2013analysis of prospective studies","volume":"32","author":"W Xu","year":"2017","journal-title":"Eur J Epidemiol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1159\/000017236","article-title":"The validity of the MMSE and SMQ as screening tests for dementia in the elderly general population: a study of one rural community in Japan","volume":"11","author":"N Maki","year":"2000","journal-title":"Dement Geriatr Cogn Disord"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/j.1365-2796.2004.01388.x","article-title":"Mild cognitive impairment as a diagnostic entity","volume":"256","author":"RC Petersen","year":"2004","journal-title":"J Intern Med"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0185960","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T04:55:55Z","timestamp":1570164955000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0185960"}},"subtitle":[],"editor":[{"given":"Hemachandra","family":"Reddy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,10,5]]},"references-count":32,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2017,10,5]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0185960","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,5]]}}}