{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:53:59Z","timestamp":1783655639614,"version":"3.55.0"},"reference-count":25,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2017,10,31]],"date-time":"2017-10-31T00:00:00Z","timestamp":1509408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81570436"],"award-info":[{"award-number":["81570436"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Foundation of Shanghai Municipal Commission of Health and Family Planning","award":["201640053"],"award-info":[{"award-number":["201640053"]}]},{"name":"Shanghai Medical Guiding Project","award":["124119a6900"],"award-info":[{"award-number":["124119a6900"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0186815","type":"journal-article","created":{"date-parts":[[2017,10,31]],"date-time":"2017-10-31T13:36:09Z","timestamp":1509456969000},"page":"e0186815","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":19,"title":["Familial hypercholesterolemia in Chinese patients with premature ST-segment-elevation myocardial infarction: Prevalence, lipid management and 1-year follow-up"],"prefix":"10.1371","volume":"12","author":[{"given":"Ranshaka","family":"Auckle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binjie","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siling","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mujin","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangchun","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Abdul Quddus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yawei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ban","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenliang","family":"Che","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,10,31]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s12929-016-0256-1","article-title":"The genetics and screening of familial hypercholesterolaemia","volume":"23","author":"R Henderson","year":"2016","journal-title":"J Biomed Sci"},{"issue":"5","key":"ref2","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1093\/aje\/kwh237","article-title":"Familial hypercholesterolemia and coronary heart disease: a HuGE association review","volume":"160","author":"MA Austin","year":"2004","journal-title":"Am J Epidemiol"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"3956","DOI":"10.1210\/jc.2012-1563","article-title":"Familial hypercholesterolemia in the danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication","volume":"97","author":"M Benn","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"issue":"9","key":"ref4","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1093\/eurheartj\/ehu058","article-title":"Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome","volume":"36","author":"B Sjouke","year":"2015","journal-title":"Eur Heart J"},{"issue":"11","key":"ref5","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1161\/CIRCULATIONAHA.115.018791","article-title":"Prevalence of Familial Hypercholesterolemia in the 1999 to 2012 United States National Health and Nutrition Examination Surveys (NHANES)","volume":"133","author":"SD de Ferranti","year":"2016","journal-title":"Circulation"},{"issue":"36","key":"ref6","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1093\/eurheartj\/ehv289","article-title":"Prevalence and management of familial hypercholesterolaemia in patients with acute coronary syndromes","volume":"36","author":"D Nanchen","year":"2015","journal-title":"Eur Heart J"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.atherosclerosis.2016.03.023","article-title":"Prevalence of heterozygous familial hypercholesterolaemia and its impact on long-term prognosis in patients with very early ST-segment elevation myocardial infarction in the era of statins","volume":"249","author":"LS Rallidis","year":"2016","journal-title":"Atherosclerosis"},{"issue":"5","key":"ref8","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.jacl.2015.07.005","article-title":"Frequency of familial hypercholesterolemia in patients with early-onset coronary artery disease admitted to a coronary care unit","volume":"9","author":"J Pang","year":"2015","journal-title":"J Clin Lipidol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ahj.2016.08.001","article-title":"The prevalence and prognostic importance of possible familial hypercholesterolemia in patients with myocardial infarction","volume":"181","author":"SA Rerup","year":"2016","journal-title":"Am Heart J"},{"issue":"6","key":"ref10","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.jacl.2016.08.013","article-title":"Identification of familial hypercholesterolemia in patients with myocardial infarction: A Chinese cohort study","volume":"10","author":"S Li","year":"2016","journal-title":"J Clin Lipidol"},{"issue":"3 Suppl","key":"ref11","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jacl.2011.04.003","article-title":"Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia","volume":"5","author":"AC Goldberg","year":"2011","journal-title":"J Clin Lipidol"},{"key":"ref12","first-page":"2863","article-title":"The Metabolic & Molecular Bases of Inherited Disease","author":"JK Goldstein","year":"2001"},{"issue":"45","key":"ref13","doi-asserted-by":"crossref","first-page":"3478","DOI":"10.1093\/eurheartj\/eht273","article-title":"Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society","volume":"34","author":"BG Nordestgaard","year":"2013","journal-title":"Eur Heart J"},{"issue":"6","key":"ref14","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.ahj.2014.09.001","article-title":"Reducing the burden of disease and death from familial hypercholesterolemia: a call to action","volume":"168","author":"JW Knowles","year":"2014","journal-title":"Am Heart J"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2165\/00019053-200725030-00002","article-title":"Economic evaluations of cholesterol-lowering drugs: a critical and systematic review","volume":"25","author":"PD Gumbs","year":"2007","journal-title":"Pharmacoeconomics"},{"issue":"2","key":"ref16","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.amjcard.2011.03.027","article-title":"Effect of lipid-lowering treatment on natural history of heterozygous familial hypercholesterolemia in past three decades","volume":"108","author":"A Elis","year":"2011","journal-title":"Am J Cardiol"},{"issue":"3","key":"ref17","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.ijcard.2014.04.165","article-title":"Familial hypercholesterolemia in China: prevalence and evidence of underdetection and undertreatment in a community population","volume":"174","author":"Z Shi","year":"2014","journal-title":"Int J Cardiol"},{"issue":"5","key":"ref18","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.jacl.2016.06.002","article-title":"Familial hypercholesterolemia among unselected contemporary patients presenting with first myocardial infarction: Prevalence, risk factor burden, and impact on age at presentation","volume":"10","author":"MB Mortensen","year":"2016","journal-title":"J Clin Lipidol"},{"issue":"1","key":"ref19","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.atherosclerosis.2015.04.809","article-title":"Prevalence and management of familial hypercholesterolaemia in coronary patients: An analysis of EUROASPIRE IV, a study of the European Society of Cardiology","volume":"241","author":"G De Backer","year":"2015","journal-title":"Atherosclerosis"},{"issue":"1","key":"ref20","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.atherosclerosis.2009.09.014","article-title":"Evaluation of cholesterol lowering treatment of patients with familial hypercholesterolemia: a large cross-sectional study in The Netherlands","volume":"209","author":"AH Pijlman","year":"2010","journal-title":"Atherosclerosis"},{"issue":"2","key":"ref21","doi-asserted-by":"crossref","first-page":"e9220","DOI":"10.1371\/journal.pone.0009220","article-title":"Two years after molecular diagnosis of familial hypercholesterolemia: majority on cholesterol-lowering treatment but a minority reaches treatment goal","volume":"5","author":"R Huijgen","year":"2010","journal-title":"PLoS One"},{"issue":"3","key":"ref22","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.jjcc.2016.05.002","article-title":"Rationale, design features, and baseline characteristics: The Heart Institute of Japan-PRoper level of lipid lOwering with Pitavastatin and Ezetimibe in acute coRonary syndrome (HIJ-PROPER)","volume":"69","author":"E Kawada-Watanabe","year":"2017","journal-title":"J Cardiol"},{"issue":"2","key":"ref23","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.atherosclerosis.2013.12.003","article-title":"The effect of moderate-dose versus double-dose statins on patients with acute coronary syndrome in China: Results of the CHILLAS trial","volume":"233","author":"SP Zhao","year":"2014","journal-title":"Atherosclerosis"},{"issue":"2","key":"ref24","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.atherosclerosis.2011.09.052","article-title":"Accelerated subclinical coronary atherosclerosis in patients with familial hypercholesterolemia","volume":"219","author":"LA Neefjes","year":"2011","journal-title":"Atherosclerosis"},{"issue":"2","key":"ref25","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1001\/jama.297.2.169","article-title":"N-terminal fragment of the prohormone brain-type natriuretic peptide (NT-proBNP), cardiovascular events, and mortality in patients with stable coronary heart disease","volume":"297","author":"K Bibbins-Domingo","year":"2007","journal-title":"Jama"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0186815","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T01:58:33Z","timestamp":1540259913000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0186815"}},"subtitle":[],"editor":[{"given":"Ying-Mei","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,10,31]]},"references-count":25,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2017,10,31]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0186815","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,31]]}}}