{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T23:30:33Z","timestamp":1794267033833,"version":"4.9.0"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2017,11,2]],"date-time":"2017-11-02T00:00:00Z","timestamp":1509580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0187081","type":"journal-article","created":{"date-parts":[[2017,11,2]],"date-time":"2017-11-02T19:44:52Z","timestamp":1509651892000},"page":"e0187081","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":22,"title":["The comparative analyses of different diagnostic approaches in detection of gastroesophageal reflux disease in children"],"prefix":"10.1371","volume":"12","author":[{"given":"Nina","family":"Ristic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Milovanovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milica","family":"Radusinovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija","family":"Stevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milos","family":"Ristic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Ristic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darija","family":"Kisic Tepavcevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara","family":"Alempijevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,11,2]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1038\/ajg.2009.129","article-title":"A global, evidence-based consensus on the definition of gastroesophageal reflux disease in the pediatric population","volume":"104","author":"PM Sherman","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1097\/MPG.0b013e3181b7f563","article-title":"Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN)","volume":"49","author":"Y Vandenplas","year":"2009","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1046\/j.1365-2036.2003.01768.x","article-title":"Different patterns of oesophageal acid exposure distinguish complicated reflux disease from either erosive reflux oesophagitis or non-erosive reflux disease","volume":"18","author":"M Frazzoni","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s11894-010-0140-1","article-title":"Symptoms and reflux in infants: Infant Gastroesophageal Reflux Questionnaire Revised (I-GERQ-R)\u2014utility for symptom tracking and diagnosis","volume":"12","author":"SR Orenstein","year":"2010","journal-title":"Curr Gastroenterol Rep"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1542\/peds.110.5.972","article-title":"Gastroesophageal reflux and cow milk allergy: is there a link?","volume":"110","author":"S Salvatore","year":"2002","journal-title":"Pediatrics"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jaci.2011.02.040","article-title":"Eosinophilic esophagitis: updated consensus recommendations for children and adults","volume":"128","author":"CA Liacouras","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.jpeds.2011.08.067","article-title":"Over-prescription of acid-suppressing medications in infants: how it came about, why it\u2019s wrong, and what to do about it","volume":"160","author":"E Hassall","year":"2012","journal-title":"J Pediatr"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1111\/nmo.12846","article-title":"The role of combined 24-h multichannel intraluminal impedance-pH monitoring in the evaluation of children with gastrointestinal symptoms suggesting gastro-esophageal reflux disease","volume":"28","author":"I Hojsak","year":"2016","journal-title":"Neurogastroenterol Motil Off J Eur Gastrointest Motil Soc"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.jpeds.2010.09.033","article-title":"Detection of gastroesophageal reflux in children using combined multichannel intraluminal impedance and pH measurement: data from the German Pediatric Impedance Group","volume":"158","author":"D Pilic","year":"2011","journal-title":"J Pediatr"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1136\/gut.2003.033290","article-title":"Gastro-oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux","volume":"53","author":"D Sifrim","year":"2004","journal-title":"Gut"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.pedneo.2015.09.008","article-title":"The Correlation between Endoscopic Reflux Esophagitis and Combined Multichannel Intraluminal Impedance-pH Monitoring in Children","volume":"57","author":"Y-W Liu","year":"2016","journal-title":"Pediatr Neonatol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"785","DOI":"10.3109\/00365521.2013.793388","article-title":"The role of baseline impedance as a marker of mucosal integrity in children with gastro esophageal reflux disease","volume":"48","author":"D Pilic","year":"2013","journal-title":"Scand J Gastroenterol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/MPG.0b013e3182592b65","article-title":"Indications, methodology, and interpretation of combined esophageal impedance-pH monitoring in children: ESPGHAN EURO-PIG standard protocol","volume":"55","author":"TG Wenzl","year":"2012","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1542\/peds.88.4.834","article-title":"Gastroesophageal reflux, as measured by 24-hour pH monitoring, in 509 healthy infants screened for risk of sudden infant death syndrome","volume":"88","author":"Y Vandenplas","year":"1991","journal-title":"Pediatrics"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.3748\/wjg.v16.i19.2401","article-title":"Disagreement between symptom-reflux association analysis parameters in pediatric gastroesophageal reflux disease investigation","volume":"16","author":"SC L\u00fcthold","year":"2010","journal-title":"World J Gastroenterol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.jpeds.2008.08.019","article-title":"Addition of pH-impedance monitoring to standard pH monitoring increases the yield of symptom association analysis in infants and children with gastroesophageal reflux","volume":"154","author":"CM Loots","year":"2009","journal-title":"J Pediatr"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0022-3468(80)80407-6","article-title":"Twenty-four hour exophageal pH monitoring in gastroesophageal reflux","volume":"15","author":"J Boix-Ochoa","year":"1980","journal-title":"J Pediatr Surg"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"e3804","DOI":"10.1097\/MD.0000000000003804","article-title":"Correlation between the different pH-metry scores in gastroesophageal reflux disease in children","volume":"95","author":"VV Lupu","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/1099-0496(200102)31:2<144::AID-PPUL1023>3.0.CO;2-Z","article-title":"Association of apnea and nonacid gastroesophageal reflux in infants: Investigations with the intraluminal impedance technique","volume":"31","author":"TG Wenzl","year":"2001","journal-title":"Pediatr Pulmonol"},{"key":"ref20","first-page":"2406","article-title":"Impedance-pH monitoring and conventional pH monitoring are complementary methods to detect association between gastroesophageal reflux and apnea-related symptoms in preterm infants and neonates","volume":"25","author":"MS Shin","year":"2012","journal-title":"J Matern-Fetal Neonatal Med Off J Eur Assoc Perinat Med Fed Asia Ocean Perinat Soc Int Soc Perinat Obstet"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/MPG.0b013e3181a4c1d8","article-title":"Comparison of esophageal pH and multichannel intraluminal impedance testing in pediatric patients with suspected gastroesophageal reflux","volume":"50","author":"R Francavilla","year":"2010","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"Suppl 3A","key":"ref22","doi-asserted-by":"crossref","first-page":"55S","DOI":"10.1016\/S0002-9343(03)00194-3","article-title":"Possible mechanisms of influence of esophageal acid on airway hyperresponsiveness","volume":"115","author":"MR Stein","year":"2003","journal-title":"Am J Med"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/MPG.0b013e31815eeabe","article-title":"Prevalence of endoscopic findings of erosive esophagitis in children: a population-based study","volume":"47","author":"MA Gilger","year":"2008","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1053\/gast.2001.29545","article-title":"Extraesophageal associations of gastroesophageal reflux disease in children without neurologic defects","volume":"121","author":"HB El-Serag","year":"2001","journal-title":"Gastroenterology"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"339","DOI":"10.4253\/wjge.v4.i8.339","article-title":"Managing gastroesophageal reflux disease in children: The role of endoscopy","volume":"4","author":"HA Goldani","year":"2012","journal-title":"World J Gastrointest Endosc"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/00000441-200311000-00006","article-title":"Diagnostic tests for gastroesophageal reflux disease","volume":"326","author":"JE Richter","year":"2003","journal-title":"Am J Med Sci"},{"issue":"Suppl 2","key":"ref27","first-page":"S1","article-title":"An evidence-based appraisal of reflux disease management\u2014the Genval Workshop Report","volume":"44","year":"1999","journal-title":"Gut"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/00005176-200502000-00024","article-title":"Gastroesophageal reflux disease in infants: how much is predictable with questionnaires, pH-metry, endoscopy and histology?","volume":"40","author":"S Salvatore","year":"2005","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1097\/MPG.0b013e3181a23dac","article-title":"Esophageal impedance and esophagitis in children: any correlation?","volume":"49","author":"S Salvatore","year":"2009","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1111\/j.1365-2982.2009.01306.x","article-title":"Relationship between gastro-oesophageal reflux pattern and severity of mucosal damage","volume":"21","author":"AJ Bredenoord","year":"2009","journal-title":"Neurogastroenterol Motil Off J Eur Gastrointest Motil Soc"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1177\/000992289603501201","article-title":"Reflux symptoms in 100 normal infants: diagnostic validity of the infant gastroesophageal reflux questionnaire","volume":"35","author":"SR Orenstein","year":"1996","journal-title":"Clin Pediatr (Phila)"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1080\/00365520510015502","article-title":"Gastroesophageal reflux disease in children: association between symptoms and pH monitoring","volume":"40","author":"K St\u00f8rdal","year":"2005","journal-title":"Scand J Gastroenterol"},{"key":"ref33","unstructured":"Loots CM. Gastroesophageal reflux in children: the use of pH-impedance measurements and new insights in treatment [Internet]. 2011. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/dare.uva.nl\/search?arno.record.id=400659\" xlink:type=\"simple\">http:\/\/dare.uva.nl\/search?arno.record.id=400659<\/ext-link>"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"815","DOI":"10.5858\/134.6.815","article-title":"Do eosinophil numbers differentiate eosinophilic esophagitis from gastroesophageal reflux disease?","volume":"134","author":"M Genevay","year":"2010","journal-title":"Arch Pathol Lab Med"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1111\/j.1572-0241.2005.50209.x","article-title":"Reassessment of the diagnostic value of histology in patients with GERD, using multiple biopsy sites and an appropriate control group","volume":"100","author":"P Zentilin","year":"2005","journal-title":"Am J Gastroenterol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0187081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,6]],"date-time":"2022-08-06T05:25:45Z","timestamp":1659763545000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0187081"}},"subtitle":[],"editor":[{"given":"Sudarshan","family":"Jadcherla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,11,2]]},"references-count":35,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2017,11,2]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0187081","relation":{"has-part":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1371\/journal.pone.0187081.g001","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1371\/journal.pone.0187081.g002","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1371\/journal.pone.0187081.t001","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1371\/journal.pone.0187081.t002","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1371\/journal.pone.0187081.t003","asserted-by":"subject"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,2]]}}}