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A systematic review","volume":"11","author":"S Tagmouti","year":"2014","journal-title":"Annals of the American Thoracic Society"},{"issue":"5","key":"ref16","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1513\/AnnalsATS.201508-532OC","article-title":"Cumulative False-Positive QuantiFERON-TB Interferon-gamma Release Assay Results","volume":"13","author":"TE Gamsky","year":"2016","journal-title":"Annals of the American Thoracic Society"},{"issue":"12","key":"ref17","first-page":"1179","article-title":"Latent Mycobacterium tuberculosis Infection","volume":"373","author":"H Getahun","year":"2015","journal-title":"The New England journal of medicine"},{"issue":"4","key":"ref18","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1128\/JCM.02803-15","article-title":"Interferon Gamma Release Assays for Latent Tuberculosis: What Are the Sources of Variability?","volume":"54","author":"N Banaei","year":"2016","journal-title":"Journal of clinical microbiology"},{"issue":"4","key":"ref19","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1017\/ice.2015.324","article-title":"Negative Tuberculin Skin Test and Prediction of Reversion of QuantiFERON Interferon Gamma Release Assay in US Healthcare Workers","volume":"37","author":"W Thanassi","year":"2016","journal-title":"Infection control and hospital epidemiology"},{"key":"ref20","unstructured":"Public Health Agency of Sweden. 2015.; <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/https:\/\/www.folkhalsomyndigheten.se\/folkhalsorapportering-statistik\/statistikdatabaser-och-visualisering\/sjukdomsstatistik\/tuberkulos\/?t=com&p=18610\" xlink:type=\"simple\">https:\/\/www.folkhalsomyndigheten.se\/folkhalsorapportering-statistik\/statistikdatabaser-och-visualisering\/sjukdomsstatistik\/tuberkulos\/?t=com&amp;p=18610<\/ext-link> last accessed 12th of december 2016."},{"issue":"7","key":"ref21","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1136\/thoraxjnl-2015-208228","article-title":"Prognostic value of interferon-gamma release assays, a population-based study from a TB low-incidence country","volume":"71","author":"TS Hermansen","year":"2016","journal-title":"Thorax"},{"issue":"5","key":"ref22","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1183\/13993003.00510-2016","article-title":"First evaluation of QuantiFERON-TB Gold Plus performance in contact screening","volume":"48","author":"L Barcellini","year":"2016","journal-title":"The European respiratory journal"},{"issue":"8","key":"ref23","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.cmi.2016.05.006","article-title":"Equal sensitivity of the new generation QuantiFERON-TB Gold plus in direct comparison with the previous test version QuantiFERON-TB Gold IT","volume":"22","author":"H Hoffmann","year":"2016","journal-title":"Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"30617","DOI":"10.1038\/srep30617","article-title":"Evaluation of QuantiFERON-TB Gold Plus for Detection of Mycobacterium tuberculosis infection in Japan","volume":"6","author":"L Yi","year":"2016","journal-title":"Scientific reports"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12995-016-0148-z","article-title":"QFT-Plus: a plus in variability?\u2014Evaluation of new generation IGRA in serial testing of students with a migration background in Germany","volume":"12","author":"J Knierer","year":"2017","journal-title":"J Occup Med Toxicol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0187313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,6]],"date-time":"2022-08-06T05:16:17Z","timestamp":1659762977000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0187313"}},"subtitle":[],"editor":[{"given":"(Amir) Homayoun","family":"Shams","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,11,2]]},"references-count":25,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2017,11,2]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0187313","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,2]]}}}