{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T05:13:18Z","timestamp":1789708398188,"version":"4.0.1"},"reference-count":30,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2017,11,9]],"date-time":"2017-11-09T00:00:00Z","timestamp":1510185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0187661","type":"journal-article","created":{"date-parts":[[2017,11,9]],"date-time":"2017-11-09T13:38:16Z","timestamp":1510234696000},"page":"e0187661","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":22,"title":["Durability of immunity by hepatitis B vaccine in Japanese health care workers depends on primary response titers and durations"],"prefix":"10.1371","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3395-9712","authenticated-orcid":true,"given":"Nori","family":"Yoshioka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matsuo","family":"Deguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideharu","family":"Hagiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Kagita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Tsukamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miyuki","family":"Takao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisao","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihisa","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiro","family":"Akeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiko","family":"Nabetani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikuhiro","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoh","family":"Hidaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunori","family":"Tomono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,11,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1016\/S0140-6736(14)60220-8","article-title":"Hepatitis B virus infection","volume":"384","author":"C Tr\u00e9po","year":"2014","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1016\/S0140-6736(15)61412-X","article-title":"Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013","volume":"386","author":"A Schweitzer","year":"2015","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/S0140-6736(81)92877-4","article-title":"Survival of hepatitis B virus after drying and storage for one week","volume":"317","author":"W Bond","year":"1981","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.4254\/wjh.v7.i18.2127","article-title":"Three decades of hepatitis B control with vaccination","volume":"7","author":"LC Meireles","year":"2015","journal-title":"World J Hepatol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1086\/314578","article-title":"What level of hepatitis B antibody is protective?","volume":"179","author":"A Jack","year":"1999","journal-title":"J Infect Dis"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1086\/606119","article-title":"Antibody levels and protection after hepatitis B vaccine: results of a 22-year follow-up study and response to a booster dose","volume":"200","author":"BJ McMahon","year":"2009","journal-title":"J Infect Dis"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"e58029","DOI":"10.1371\/journal.pone.0058029","article-title":"Observational study of vaccine efficacy 24 years after the start of hepatitis B vaccination in two Gambian villages: no need for a booster dose","volume":"8","author":"M Mendy","year":"2013","journal-title":"PloS one"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.vaccine.2012.10.101","article-title":"Hepatitis B vaccination: A completed schedule enough to control HBV lifelong?: Milan, Italy, 17\u201318 November 2011","volume":"31","author":"D FitzSimons","year":"2013","journal-title":"Vaccine"},{"key":"ref9","first-page":"1","article-title":"CDC guidance for evaluating health-care personnel for hepatitis B virus protection and for administering postexposure management","volume":"62","author":"S Schillie","year":"2013","journal-title":"MMWR Recomm Rep"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0140-6736(99)07239-6","article-title":"Are booster immunisations needed for lifelong hepatitis B immunity?","volume":"355","author":"M Kane","year":"2000","journal-title":"Lancet"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"333","DOI":"10.7326\/0003-4819-142-5-200503010-00008","article-title":"Antibody levels and protection after hepatitis B vaccination: results of a 15-year follow-up","volume":"142","author":"BJ McMahon","year":"2005","journal-title":"Ann Intern Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1002\/hep.20490","article-title":"Waning immunity to plasma\u2010derived hepatitis B vaccine and the need for boosters 15 years after neonatal vaccination","volume":"40","author":"CY Lu","year":"2004","journal-title":"Hepatology"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1056\/NEJMoa1007644","article-title":"Nucleic acid testing to detect HBV infection in blood donors","volume":"364","author":"SL Stramer","year":"2011","journal-title":"N Engl J Med"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.jhep.2008.07.040","article-title":"Acute hepatitis B in a healthcare worker: a case report of genuine vaccination failure","volume":"50","author":"HJ Boot","year":"2009","journal-title":"J Hepatol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jcv.2011.06.020","article-title":"Hepatitis B virus vaccine failure resulting in chronic hepatitis B infection","volume":"52","author":"JA O'Halloran","year":"2011","journal-title":"J Clin Virol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/S1473-3099(16)30463-7","article-title":"Introduction of a hepatitis B vaccine into the national routine immunisation programme of Japan","volume":"16","author":"M Ujiie","year":"2016","journal-title":"Lancet Infect Dis"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"285","DOI":"10.7326\/0003-4819-88-3-285","article-title":"Type B hepatitis after needle-stick exposure: prevention with hepatitis B immune globulin. Final report of the Veterans Administration Cooperative Study","volume":"88","author":"LB Seeff","year":"1978","journal-title":"Ann Intern Med"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"e52","DOI":"10.1086\/590968","article-title":"Group JdnHBR. Mortality secondary to fulminant hepatic failure in patients with prior resolution of hepatitis B virus infection in Japan","volume":"47","author":"T Umemura","year":"2008","journal-title":"Clin Infect Dis"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"590","DOI":"10.2105\/AJPH.80.5.590","article-title":"Persistence of anti-HBs among health care personnel immunized with hepatitis B vaccine","volume":"80","author":"MT Pasko","year":"1990","journal-title":"Am J Public Health"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1001\/archinte.159.13.1481","article-title":"Serologic hepatitis B immunity in vaccinated health care workers","volume":"159","author":"C Barash","year":"1999","journal-title":"Arch Intern Med"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000046064","article-title":"Persistence of immunologic memory in long-term hemodialysis patients and healthcare workers given hepatitis B vaccine: role of a booster dose on antibody response","volume":"89","author":"R Peces","year":"2001","journal-title":"Nephron"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1086\/502132","article-title":"Ten-year persistence of antibody to hepatitis B surface antigen in healthcare workers vaccinated against hepatitis B virus, and response to booster vaccination","volume":"24","author":"R Durlach","year":"2003","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.vaccine.2003.09.001","article-title":"Long-term persistence of anti-HBs after vaccination against HBV: an 18 year experience in health care workers","volume":"22","author":"A Floreani","year":"2004","journal-title":"Vaccine"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1093\/cid\/ciu867","article-title":"Durability of antibody response against hepatitis B virus in healthcare workers vaccinated as adults","volume":"60","author":"N Gara","year":"2015","journal-title":"Clin Infect Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0749-3797(98)00003-8","article-title":"Immunogenicity of hepatitis B vaccines: implications for persons at occupational risk of hepatitis B virus infection","volume":"15","author":"F Averhoff","year":"1998","journal-title":"Am J Prev Med"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.3748\/wjg.v9.i5.1132","article-title":"Immunogenicity and reactogenicity of a recombinant hepatitis B vaccine in subjects over age of forty years and response of a booster dose among nonresponders","volume":"9","author":"K Das","year":"2003","journal-title":"World J Gastroenterol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/j.1532-5415.1996.tb01835.x","article-title":"Hepatitis B virus vaccination for older adults","volume":"44","author":"RG Bennett","year":"1996","journal-title":"J Am Geriatr Soc"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1093\/infdis\/149.6.1019","article-title":"Hepatitis-B vaccination in the elderly","volume":"149","author":"F Denis","year":"1984","journal-title":"J Infect Dis"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"e1898","DOI":"10.1371\/journal.pone.0001898","article-title":"Host genetic factors and vaccine-induced immunity to hepatitis B virus infection","volume":"3","author":"BJ Hennig","year":"2008","journal-title":"PloS one"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.idc.2006.01.004","article-title":"Hepatitis B vaccines","volume":"20","author":"AS Yu","year":"2006","journal-title":"Infect Dis Clin North Am"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0187661","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T21:21:25Z","timestamp":1540243285000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0187661"}},"subtitle":[],"editor":[{"given":"Jason","family":"Blackard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,11,9]]},"references-count":30,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2017,11,9]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0187661","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,9]]}}}