{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:14:13Z","timestamp":1791666853608,"version":"4.3.4"},"reference-count":52,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T00:00:00Z","timestamp":1509926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0187764","type":"journal-article","created":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T18:35:38Z","timestamp":1509993338000},"page":"e0187764","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":70,"title":["Incidence and outcomes of acute kidney injury in extremely-low-birth-weight infants"],"prefix":"10.1371","volume":"12","author":[{"given":"Chien-Chung","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oi-Wa","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Yin","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Hsiang","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tai-Wei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wai-Ho","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Cheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4571-0298","authenticated-orcid":true,"given":"Reyin","family":"Lien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,11,6]]},"reference":[{"issue":"7","key":"ref1","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1681\/ASN.2010121266","article-title":"Accelerated maturation and abnormal morphology in the preterm neonatal kidney","volume":"22","author":"MR Sutherland","year":"2011","journal-title":"J Am Soc Nephrol"},{"issue":"2","key":"ref2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0272-6386(12)80967-X","article-title":"Congenital oligonephropathy and the etiology of adult hypertension and progressive renal injury","volume":"23","author":"BM Brenner","year":"1994","journal-title":"Am J Kidney Dis"},{"issue":"4","key":"ref3","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/ajh\/1.4.335","article-title":"Glomeruli and blood pressure. Less of one, more the other?","volume":"1","author":"BM Brenner","year":"1988","journal-title":"Am J Hypertens"},{"issue":"1","key":"ref4","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1681\/ASN.2007020252","article-title":"Low birth weight increases risk for end-stage renal disease","volume":"19","author":"BE Vikse","year":"2008","journal-title":"J Am Soc Nephrol"},{"issue":"6","key":"ref5","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1542\/peds.2013-0009","article-title":"Short-term gestation, long-term risk: prematurity and chronic kidney disease","volume":"131","author":"JB Carmody","year":"2013","journal-title":"Pediatrics"},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1007\/s00467-009-1133-x","article-title":"Acute kidney injury is independently associated with mortality in very low birthweight infants: a matched case-control analysis","volume":"24","author":"DJ Askenazi","year":"2009","journal-title":"Pediatr Nephrol"},{"issue":"4","key":"ref7","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1203\/PDR.0b013e31820b95ca","article-title":"Acute kidney injury reduces survival in very low birth weight infants","volume":"69","author":"R Koralkar","year":"2011","journal-title":"Pediatr Res"},{"issue":"12","key":"ref8","doi-asserted-by":"crossref","first-page":"e84892","DOI":"10.1371\/journal.pone.0084892","article-title":"Critical serum creatinine values in very preterm newborns","volume":"8","author":"A Bruel","year":"2013","journal-title":"PLoS One"},{"issue":"11","key":"ref9","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1007\/s00467-014-2837-0","article-title":"Acute kidney injury in preterm infants admitted to a neonatal intensive care unit","volume":"29","author":"V Stojanovic","year":"2014","journal-title":"Pediatr Nephrol"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"e463","DOI":"10.1542\/peds.2014-3819","article-title":"Neonatal Acute Kidney Injury","volume":"136","author":"DT Selewski","year":"2015","journal-title":"Pediatrics"},{"issue":"1\u20132","key":"ref11","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s004670000356","article-title":"Progression of renal function in preterm neonates with gestational age < or = 32 weeks","volume":"15","author":"F Gallini","year":"2000","journal-title":"Pediatr Nephrol"},{"issue":"12","key":"ref12","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/sj.jp.7211604","article-title":"Serum creatinine in very low birth weight infants during their first days of life","volume":"26","author":"A Auron","year":"2006","journal-title":"J Perinatol"},{"issue":"3","key":"ref13","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/sj.jp.7211905","article-title":"A gestation- and postnatal age-based reference chart for assessing renal function in extremely premature infants","volume":"28","author":"S Thayyil","year":"2008","journal-title":"Journal of perinatology: official journal of the California Perinatal Association"},{"issue":"5","key":"ref14","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1038\/pr.2015.25","article-title":"Serum creatinine concentration in very-low-birth-weight infants from birth to 34\u201336 wk postmenstrual age","volume":"77","author":"DA Bateman","year":"2015","journal-title":"Pediatr Res"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/jp.2010.82","article-title":"Elevation in plasma creatinine and renal failure in premature neonates without major anomalies: terminology, occurrence and factors associated with increased risk","volume":"31","author":"MW Walker","year":"2011","journal-title":"J Perinatol"},{"issue":"6","key":"ref16","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.jpeds.2011.05.045","article-title":"Urine biomarkers predict acute kidney injury and mortality in very low birth weight infants","volume":"159","author":"DJ Askenazi","year":"2011","journal-title":"The Journal of pediatrics"},{"issue":"6","key":"ref17","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.jpeds.2010.12.057","article-title":"Neutrophil gelatinase-associated lipocalin concentrations predict development of acute kidney injury in neonates and children after cardiopulmonary bypass","volume":"158","author":"CD Krawczeski","year":"2011","journal-title":"J Pediatr"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.jtcvs.2011.06.021","article-title":"Congenital heart surgery in infants: effects of acute kidney injury on outcomes","volume":"143","author":"JJ Blinder","year":"2012","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"7","key":"ref19","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1007\/s00467-013-2454-3","article-title":"Epidemiology of cardiac surgery-associated acute kidney injury in neonates: a retrospective study","volume":"28","author":"A Alabbas","year":"2013","journal-title":"Pediatr Nephrol"},{"issue":"10","key":"ref20","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/sj.ki.5002231","article-title":"Modified RIFLE criteria in critically ill children with acute kidney injury","volume":"71","author":"A Akcan-Arikan","year":"2007","journal-title":"Kidney Int"},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.jpedsurg.2010.11.031","article-title":"Acute kidney injury in congenital diaphragmatic hernia requiring extracorporeal life support: an insidious problem","volume":"46","author":"SK Gadepalli","year":"2011","journal-title":"J Pediatr Surg"},{"issue":"4","key":"ref22","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1093\/ndt\/gfs604","article-title":"Defining reduced urine output in neonatal ICU: importance for mortality and acute kidney injury classification","volume":"28","author":"CT Bezerra","year":"2013","journal-title":"Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association\u2014European Renal Association"},{"issue":"4","key":"ref23","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/ki.2011.41","article-title":"Urinary neutrophil gelatinase-associated lipocalin distinguishes pre-renal from intrinsic renal failure and predicts outcomes","volume":"80","author":"E Singer","year":"2011","journal-title":"Kidney Int"},{"issue":"1","key":"ref24","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/cc11454","article-title":"Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1)","volume":"17","author":"JA Kellum","year":"2013","journal-title":"Crit Care"},{"issue":"2","key":"ref25","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/MOP.0b013e32834f62d5","article-title":"Update on acute kidney injury in the neonate","volume":"24","author":"JG Jetton","year":"2012","journal-title":"Curr Opin Pediatr"},{"issue":"3","key":"ref26","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1081\/JDI-200026749","article-title":"Acute renal failure in the neonatal period","volume":"26","author":"PI Agras","year":"2004","journal-title":"Ren Fail"},{"issue":"5","key":"ref27","doi-asserted-by":"crossref","first-page":"F388","DOI":"10.1136\/adc.2005.092023","article-title":"Acute renal insufficiency in the neonatal intensive care unit","volume":"91","author":"AJ Lunn","year":"2006","journal-title":"Archives of disease in childhood Fetal and neonatal edition"},{"issue":"3","key":"ref28","first-page":"136","article-title":"Acute kidney failure in neonatal period","volume":"3","author":"F Mortazavi","year":"2009","journal-title":"Iran J Kidney Dis"},{"issue":"3","key":"ref29","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1093\/ndt\/gfr477","article-title":"Neonatal acute kidney injury in a tertiary center in a developing country","volume":"27","author":"P Vachvanichsanong","year":"2012","journal-title":"Nephrol Dial Transplant"},{"issue":"4","key":"ref30","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s12519-012-0371-3","article-title":"Acute kidney injury in a single neonatal intensive care unit in Turkey","volume":"9","author":"F Bolat","year":"2013","journal-title":"World J Pediatr"},{"issue":"4","key":"ref31","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1093\/ndt\/gfs604","article-title":"Defining reduced urine output in neonatal ICU: importance for mortality and acute kidney injury classification","volume":"28","author":"CT Bezerra","year":"2013","journal-title":"Nephrol Dial Transplant"},{"issue":"12","key":"ref32","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.2215\/CJN.05190514","article-title":"Recognition and reporting of AKI in very low birth weight infants","volume":"9","author":"JB Carmody","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref33","article-title":"Comparison of different definitions of acute kidney injury in extremely low birth weight infants","author":"V Chowdhary","year":"2017","journal-title":"Clin Exp Nephrol"},{"issue":"14","key":"ref34","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.3109\/14767058.2013.860522","article-title":"Nephrotoxic medication exposure in very low birth weight infants","volume":"27","author":"ET Rhone","year":"2014","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"3","key":"ref35","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.clp.2014.05.001","article-title":"Acute kidney injury in the neonate","volume":"41","author":"JG Jetton","year":"2014","journal-title":"Clin Perinatol"},{"issue":"6","key":"ref36","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.jpeds.2005.01.047","article-title":"Extremely low birthweight neonates with protracted ventilation: mortality and 18-month neurodevelopmental outcomes","volume":"146","author":"MC Walsh","year":"2005","journal-title":"J Pediatr"},{"issue":"2","key":"ref37","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00467-011-1977-8","article-title":"Risk factors associated with acute kidney injury in extremely low birth weight (ELBW) infants","volume":"27","author":"S Viswanathan","year":"2012","journal-title":"Pediatr Nephrol"},{"issue":"5","key":"ref38","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1093\/tropej\/fmi017","article-title":"Evaluation of renal functions in asphyxiated newborns","volume":"51","author":"A Aggarwal","year":"2005","journal-title":"J Trop Pediatr"},{"issue":"2","key":"ref39","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1179\/146532811X12925735813922","article-title":"Evaluation of glomerular and tubular renal function in neonates with birth asphyxia","volume":"31","author":"S Kaur","year":"2011","journal-title":"Ann Trop Paediatr"},{"issue":"4","key":"ref40","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.jpeds.2012.10.002","article-title":"Acute kidney injury in asphyxiated newborns treated with therapeutic hypothermia","volume":"162","author":"DT Selewski","year":"2013","journal-title":"J Pediatr"},{"issue":"6","key":"ref41","doi-asserted-by":"crossref","first-page":"F514","DOI":"10.1136\/adc.2004.060434","article-title":"Potential risk factors for the development of acute renal failure in preterm newborn infants: a case-control study","volume":"90","author":"L Cataldi","year":"2005","journal-title":"Archives of disease in childhood Fetal and neonatal edition"},{"issue":"7","key":"ref42","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1007\/s00467-006-0118-2","article-title":"Postnatal renal function in preterm newborns: a role of diseases, drugs and therapeutic interventions","volume":"21","author":"L Cuzzolin","year":"2006","journal-title":"Pediatr Nephrol"},{"issue":"4","key":"ref43","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s00467-012-2369-4","article-title":"Fluid overload and mortality are associated with acute kidney injury in sick near-term\/term neonate","volume":"28","author":"DJ Askenazi","year":"2013","journal-title":"Pediatric nephrology (Berlin, Germany)"},{"issue":"9","key":"ref44","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1007\/s00467-015-3087-5","article-title":"Acute kidney injury is associated with bronchopulmonary dysplasia\/mortality in premature infants","volume":"30","author":"D Askenazi","year":"2015","journal-title":"Pediatr Nephrol"},{"issue":"1","key":"ref45","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1681\/ASN.2006050494","article-title":"Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury","volume":"18","author":"TS Hoke","year":"2007","journal-title":"J Am Soc Nephrol"},{"issue":"1","key":"ref46","doi-asserted-by":"crossref","first-page":"L3","DOI":"10.1152\/ajplung.00030.2008","article-title":"Interactive effects of mechanical ventilation and kidney health on lung function in an in vivo mouse model","volume":"296","author":"OJ Dodd","year":"2009","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"1","key":"ref47","doi-asserted-by":"crossref","first-page":"F125","DOI":"10.1152\/ajprenal.90666.2008","article-title":"Kidney ischemia-reperfusion injury induces caspase-dependent pulmonary apoptosis","volume":"297","author":"HT Hassoun","year":"2009","journal-title":"Am J Physiol Renal Physiol"},{"issue":"4","key":"ref48","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1111\/j.1440-1797.2012.01577.x","article-title":"Risk factors for the prognosis of acute kidney injury under the Acute Kidney Injury Network definition: a retrospective, multicenter study in critically ill patients","volume":"17","author":"J Zhou","year":"2012","journal-title":"Nephrology (Carlton, Vic)"},{"issue":"9","key":"ref49","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.2215\/CJN.00710113","article-title":"World incidence of AKI: a meta-analysis","volume":"8","author":"P Susantitaphong","year":"2013","journal-title":"Clin J Am Soc Nephrol"},{"issue":"6","key":"ref50","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1053\/j.ajkd.2008.11.034","article-title":"Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and meta-analysis","volume":"53","author":"SG Coca","year":"2009","journal-title":"Am J Kidney Dis"},{"issue":"5","key":"ref51","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1053\/j.ajkd.2007.07.018","article-title":"The prognostic importance of a small acute decrement in kidney function in hospitalized patients: a systematic review and meta-analysis","volume":"50","author":"SG Coca","year":"2007","journal-title":"Am J Kidney Dis"},{"issue":"9","key":"ref52","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/ki.2011.339","article-title":"AKI in the ICU: definition, epidemiology, risk stratification, and outcomes","volume":"81","author":"K Singbartl","year":"2012","journal-title":"Kidney Int"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0187764","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T04:17:30Z","timestamp":1588997850000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0187764"}},"subtitle":[],"editor":[{"given":"Nick","family":"Ashton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,11,6]]},"references-count":52,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2017,11,6]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0187764","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,6]]}}}