{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T01:35:33Z","timestamp":1773884133176,"version":"3.50.1"},"reference-count":64,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T00:00:00Z","timestamp":1510704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["1R01AI123457"],"award-info":[{"award-number":["1R01AI123457"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["RO1 AI 89808-01"],"award-info":[{"award-number":["RO1 AI 89808-01"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0188040","type":"journal-article","created":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T18:35:34Z","timestamp":1510770934000},"page":"e0188040","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":12,"title":["Lack of mitochondrial MutS homolog 1 in Toxoplasma gondii disrupts maintenance and fidelity of mitochondrial DNA and reveals metabolic plasticity"],"prefix":"10.1371","volume":"12","author":[{"given":"Tamila","family":"Garbuz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4445-0375","authenticated-orcid":true,"given":"Gustavo","family":"Arrizabalaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2017,11,15]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1016\/S0140-6736(04)16412-X","article-title":"Toxoplasmosis","volume":"363","author":"JG Montoya","year":"2004","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"794","DOI":"10.4269\/ajtmh.13-0722","article-title":"Neglected Parasitic Infections in the United States: Toxoplasmosis","volume":"90","author":"JL Jones","year":"2014","journal-title":"Am J Trop Med Hyg"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.pt.2016.10.002","article-title":"Is the Mitochondrion a Good Malaria Drug Target?","volume":"33","author":"CD Goodman","year":"2017","journal-title":"Trends Parasitol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.mib.2013.07.003","article-title":"The metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium spp","volume":"16","author":"L Sheiner","year":"2013","journal-title":"Curr Opin Microbiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s10863-008-9176-4","article-title":"Mitochondria in malaria and related parasites: ancient, diverse and streamlined","volume":"40","author":"MW Mather","year":"2008","journal-title":"J Bioenerg Biomembr"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1046\/j.1365-2958.1999.01515.x","article-title":"Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites","volume":"33","author":"IK Srivastava","year":"1999","journal-title":"Mol Microbiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"3961","DOI":"10.1074\/jbc.272.7.3961","article-title":"Atovaquone, a broad spectrum antiparasitic drug, collapses mitochondrial membrane potential in a malarial parasite","volume":"272","author":"IK Srivastava","year":"1997","journal-title":"J Biol Chem"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"31040","DOI":"10.1074\/jbc.273.47.31040","article-title":"Respiration and oxidative phosphorylation in the apicomplexan parasite <italic>Toxoplasma gondii<\/italic>","volume":"273","author":"AE Vercesi","year":"1998","journal-title":"J Biol Chem"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0166-6851(00)00184-5","article-title":"Characterization of cytochrome b from <italic>Toxoplasma gondii<\/italic> and Q(o) domain mutations as a mechanism of atovaquone-resistance","volume":"108","author":"DC McFadden","year":"2000","journal-title":"Mol Biochem Parasitol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1093\/jac\/dks504","article-title":"Antimalarial pharmacology and therapeutics of atovaquone","volume":"68","author":"GL Nixon","year":"2013","journal-title":"J Antimicrob Chemother"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/0022-2836(91)90494-Q","article-title":"Mitochondrial-like DNA sequences flanked by direct and inverted repeats in the nuclear genome of <italic>Toxoplasma gondii<\/italic>","volume":"222","author":"PN Ossorio","year":"1991","journal-title":"J Mol Biol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1550-7408.1991.tb04436.x","article-title":"The putative mitochondrial genome of <italic>Plasmodium falciparum<\/italic>","volume":"38","author":"JE Feagin","year":"1991","journal-title":"J Protozool"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/nrm3439","article-title":"Minimizing the damage: repair pathways keep mitochondrial DNA intact","volume":"13","author":"L Kazak","year":"2012","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1093\/nar\/gkg167","article-title":"Mismatch repair activity in mammalian mitochondria","volume":"31","author":"PA Mason","year":"2003","journal-title":"Nucleic Acids Res"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.dnarep.2009.01.021","article-title":"Novel DNA mismatch-repair activity involving YB-1 in human mitochondria","volume":"8","author":"NC de Souza-Pinto","year":"2009","journal-title":"DNA Repair"},{"key":"ref16","article-title":"Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: Evidence for mismatch repair systems in mitochondrial genome","volume":"17","year":"1998","journal-title":"Publ Online"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1093\/genetics\/132.4.975","article-title":"Characterization of insertion mutations in the <italic>Saccharomyces cerevisiae<\/italic> MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions","volume":"132","author":"R Reenan","year":"1992","journal-title":"Genetics"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"29993","DOI":"10.1016\/S0021-9258(18)43979-8","article-title":"The Effect of DNA Mismatches on the ATPase Activity of MSH1, a Protein in Yeast Mitochondria That Recognizes DNA Mismatches","volume":"269","author":"N Chi","year":"1994","journal-title":"J Biol Chem"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"29984","DOI":"10.1016\/S0021-9258(18)43978-6","article-title":"Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches","volume":"269","author":"NW Chi","year":"1994","journal-title":"J Biol Chem"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"5968","DOI":"10.1073\/pnas.1037651100","article-title":"Substoichiometric shifting in the plant mitochondrial genome is influenced by a gene homologous to MutS","volume":"100","author":"RV Abdelnoor","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1365-2958.2009.06655.x","article-title":"Disruption of a mitochondrial MutS DNA repair enzyme homologue confers drug resistance in the parasite <italic>Toxoplasma gondii<\/italic>","volume":"72","author":"EM Garrison","year":"2009","journal-title":"Mol Microbiol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1128\/AAC.01092-10","article-title":"The antibiotic monensin causes cell cycle disruption of <italic>Toxoplasma gondii<\/italic> mediated through the DNA repair enzyme TgMSH-1","volume":"55","author":"MD Lavine","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"e42107","DOI":"10.1371\/journal.pone.0042107","article-title":"Analysis of Monensin Sensitivity in <italic>Toxoplasma gondii<\/italic> Reveals Autophagy as a Mechanism for Drug Induced Death","volume":"7","author":"MD Lavine","year":"2012","journal-title":"PloS One"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/35037509","article-title":"Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA","volume":"407","author":"G Obmolova","year":"2000","journal-title":"Nature"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1146\/annurev.biochem.74.082803.133243","article-title":"DNA Mismatch Repair*","volume":"74","author":"T Kunkel","year":"2005","journal-title":"Annu Rev Biochem"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/35037523","article-title":"The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch","volume":"407","author":"MH Lamers","year":"2000","journal-title":"Nature"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s00239-005-0226-9","article-title":"Mitochondrial genome dynamics in plants and animals: convergent gene fusions of a MutS homologue","volume":"63","author":"RV Abdelnoor","year":"2006","journal-title":"J Mol Evol"},{"key":"ref28","first-page":"81S","article-title":"Cytochrome b mutation identified in a decoquinate-resistant mutant of <italic>Toxoplasma gondii<\/italic>","volume":"46","author":"D McFadden","year":"1999","journal-title":"J Eukaryot"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"23690","DOI":"10.1074\/jbc.273.37.23690","article-title":"The role of 3\u2019-5\u2019 exonucleolytic proofreading and mismatch repair in yeast mitochondrial DNA error avoidance","volume":"273","author":"S Vanderstraeten","year":"1998","journal-title":"J Biol Chem"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1007\/s00294-004-0537-1","article-title":"Analysis of the functional domains of the mismatch repair homologue Msh1p and its role in mitochondrial genome maintenance","volume":"47","author":"S a Mookerjee","year":"2005","journal-title":"Curr Genet"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"e1003049","DOI":"10.1371\/journal.ppat.1003049","article-title":"A Forward Genetic Screen Reveals that Calcium-dependent Protein Kinase 3 Regulates Egress in <italic>Toxoplasma<\/italic>","volume":"8","author":"E Garrison","year":"2012","journal-title":"PLoS Pathog"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1006\/expr.2001.4639","article-title":"<italic>Plasmodium falciparum<\/italic>: the effects of atovaquone resistance on respiration","volume":"98","author":"E Suswam","year":"2001","journal-title":"Exp Parasitol"},{"key":"ref33","first-page":"283","article-title":"Atovaquone resistance in malaria parasites","volume":"3","author":"AB Vaidya","year":"2000","journal-title":"Drug Resist Updat Rev Comment Antimicrob Anticancer Chemother"},{"key":"ref34","first-page":"64","article-title":"A drug-selected <italic>Plasmodium falciparum<\/italic> lacking the need for conventional electron transport","volume":"159","author":"MJ Smilkstein","year":"2009","journal-title":"A drug-selected"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0166-6851(86)90066-6","article-title":"Altered dihydrofolate reductase in pyrimethamine-resistant <italic>Plasmodium falciparum<\/italic>","volume":"19","author":"RD Walter","year":"1986","journal-title":"Mol Biochem Parasitol"},{"key":"ref36","first-page":"630","article-title":"Relative reversal by vitamins (rho-aminobenzoic, folic, and folinic acids) of the effects of sulfadiazine and pyrimethamine on <italic>Toxoplasma<\/italic>, mouse and man","volume":"7","author":"JK Frenkel","year":"1957","journal-title":"Antibiot Chemother Northfield Ill"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0166-6851(94)90060-4","article-title":"Homologous recombination and gene replacement at the dihydrofolate reductase-thymidylate synthase locus in <italic>Toxoplasma gondii<\/italic>","volume":"63","author":"R Donald","year":"1994","journal-title":"Mol Biochem Parasitol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1046\/j.1365-2958.2002.02825.x","article-title":"An rRNA mutation identifies the apicoplast as the target for clindamycin in <italic>Toxoplasma gondii<\/italic>","volume":"43","author":"M Camps","year":"2002","journal-title":"Mol Microbiol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.dnarep.2008.11.004","article-title":"Msh1p counteracts oxidative lesion-induced instability of mtDNA and stimulates mitochondrial recombination in <italic>Saccharomyces cerevisiae<\/italic>","volume":"8","author":"A Kaniak","year":"2009","journal-title":"DNA Repair"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1534\/genetics.109.103796","article-title":"Evidence that msh1p plays multiple roles in mitochondrial base excision repair","volume":"182","author":"L Pogorzala","year":"2009","journal-title":"Genetics"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1105\/tpc.106.048355","article-title":"Plant Mitochondrial Recombination Surveillance Requires Unusual RecA and MutS Homologs","volume":"19","author":"V Shedge","year":"2007","journal-title":"Plant Cell Online"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1105\/tpc.8.8.1377","article-title":"Altered mitochondrial gene expression in a maternal distorted leaf mutant of Arabidopsis induced by chloroplast mutator","volume":"8","author":"W Sakamoto","year":"1996","journal-title":"Plant Cell"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1002\/j.1460-2075.1987.tb04832.x","article-title":"Stoichiometric differences in DNA molecules containing the atpA gene suggest mechanisms for the generation of mitochondrial genome diversity in maize","volume":"6","author":"ID Small","year":"1987","journal-title":"EMBO J"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0166-6851(89)90112-6","article-title":"Sequences similar to genes for two mitochondrial proteins and portions of ribosomal RNA in tandemly arrayed 6-kilobase-pair DNA of a malarial parasite","volume":"35","author":"AB Vaidya","year":"1989","journal-title":"Mol Biochem Parasitol"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0166-6851(88)90098-9","article-title":"Molecular cloning and partial sequence of a 5.8 kilobase pair repetitive DNA from <italic>Plasmodium falciparum<\/italic>","volume":"30","author":"K Suplick","year":"1988","journal-title":"Mol Biochem Parasitol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0166-6851(87)90056-9","article-title":"Tandemly arranged gene clusters of malarial parasites that are highly conserved and transcribed","volume":"22","author":"AB Vaidya","year":"1987","journal-title":"Mol Biochem Parasitol"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1146\/annurev.mi.48.100194.000501","article-title":"The Extrachromosomal DNAs of Apicomplexan Parasites","volume":"48","author":"JE Feagin","year":"1994","journal-title":"Annu Rev Microbiol"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0166-6851(92)90046-M","article-title":"The 6-kb element of <italic>Plasmodium falciparum<\/italic> encodes mitochondrial cytochrome genes","volume":"52","author":"JE Feagin","year":"1992","journal-title":"Mol Biochem Parasitol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1093\/nar\/20.4.879","article-title":"Homologies between the contiguous and fragmented rRNAs of the two <italic>Plasmodium falciparum<\/italic> extrachromosomal DNAs are limited to core sequences","volume":"20","author":"JE Feagin","year":"1992","journal-title":"Nucleic Acids Res"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0166-6851(88)90140-5","article-title":"Mitochondrial DNA of the human malarial parasite <italic>Plasmodium falciparum<\/italic>","volume":"31","author":"MJ Gardner","year":"1988","journal-title":"Mol Biochem Parasitol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"3621","DOI":"10.1128\/MCB.9.9.3621","article-title":"Characterization of a conserved extrachromosomal element isolated from the avian malarial parasite <italic>Plasmodium gallinaceum<\/italic>","volume":"9","author":"JT Joseph","year":"1989","journal-title":"Mol Cell Biol"},{"key":"ref52","first-page":"185","article-title":"Mutations in the cytochrome b gene of <italic>Plasmodium berghei<\/italic> conferring resistance to atovaquone","volume":"104","author":"D Syafruddin","year":"1999","journal-title":"Mol Biochem"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1128\/AAC.44.8.2100-2108.2000","article-title":"Mutations in <italic>Plasmodium falciparum<\/italic> cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site","volume":"44","author":"M Korsinczky","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"key":"ref54","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofu059","article-title":"Novel Mutation in Cytochrome B of <italic>Plasmodium falciparum<\/italic> in One of Two Atovaquone-Proguanil Treatment Failures in Travelers Returning From Same Site in Nigeria","volume":"1","author":"MM Plucinski","year":"2014","journal-title":"Open Forum Infect Dis"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"4029","DOI":"10.1038\/ncomms5029","article-title":"Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action","volume":"5","author":"D Birth","year":"2014","journal-title":"Nat Commun"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"12564","DOI":"10.1016\/S0021-9258(18)37792-5","article-title":"Molecular basis for resistance to antimycin and diuron, Q-cycle inhibitors acting at the Qi site in the mitochondrial ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae","volume":"263","author":"JP di Rago","year":"1988","journal-title":"J Biol Chem"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"704","DOI":"10.2174\/138161282005140214163327","article-title":"Structural Basis of Resistance to Anti-Cytochrome bc1 Complex Inhibitors: Implication for Drug Improvement","volume":"20","author":"L Esser","year":"2014","journal-title":"Curr Pharm Des"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1016\/0006-2952(84)90581-1","article-title":"Potent and selective hydroxynaphthoquinone inhibitors of mitochondrial electron transport in <italic>Eimeria tenella<\/italic> (Apicomplexa: Coccidia)","volume":"33","author":"M Fry","year":"1984","journal-title":"Biochem Pharmacol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.exppara.2006.03.014","article-title":"Evaluation and lead optimization of anti-malarial acridones","volume":"114","author":"RW Winter","year":"2006","journal-title":"Exp Parasitol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/nature05572","article-title":"Specific role of mitochondrial electron transport in blood-stage <italic>Plasmodium falciparum<\/italic>","volume":"446","author":"HJ Painter","year":"2007","journal-title":"Nature"},{"key":"ref61","first-page":"559","article-title":"Mutants of <italic>Toxoplasma gondii<\/italic> resistant to Atovaquone (566C80) or Decoquinate","volume":"79","author":"ER Pfefferkorn","year":"1993","journal-title":"Mutants of"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1016\/j.ijpara.2007.05.010","article-title":"<italic>Toxoplasma gondii<\/italic>: induction of egress by the potassium ionophore nigericin","volume":"37","author":"I a Fruth","year":"2007","journal-title":"Int J Parasitol"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/0014-4894(90)90071-J","article-title":"<italic>Plasmodium falciparum<\/italic>: ATP\/ADP transport across the parasitophorous vacuolar and plasma membranes","volume":"71","author":"I Choi","year":"1990","journal-title":"Exp Parasitol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1128\/AAC.41.9.1849","article-title":"Use of <italic>Toxoplasma gondii<\/italic> expressing beta-galactosidase for colorimetric assessment of drug activity in vitro","volume":"41","author":"DC McFadden","year":"1997","journal-title":"Antimicrob Agents Chemother"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0188040","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,7]],"date-time":"2022-08-07T11:35:50Z","timestamp":1659872150000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0188040"}},"subtitle":[],"editor":[{"given":"Ira J","family":"Blader","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2017,11,15]]},"references-count":64,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2017,11,15]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0188040","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,15]]}}}