{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T15:33:46Z","timestamp":1775057626861,"version":"3.50.1"},"reference-count":56,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2018,1,25]],"date-time":"2018-01-25T00:00:00Z","timestamp":1516838400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research Foundation of Korea (KR)","award":["2016R1C1B2007911"],"award-info":[{"award-number":["2016R1C1B2007911"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0191858","type":"journal-article","created":{"date-parts":[[2018,1,25]],"date-time":"2018-01-25T18:47:27Z","timestamp":1516906047000},"page":"e0191858","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":16,"title":["Increased parietal circuit-breaker activity in delta frequency band and abnormal delta\/theta band connectivity in salience network in hyperacusis subjects"],"prefix":"10.1371","volume":"13","author":[{"given":"Jae Joon","family":"Han","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Hye","family":"Jang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk De","family":"Ridder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Vanneste","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ja-Won","family":"Koo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6631-3232","authenticated-orcid":true,"given":"Jae-Jin","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2018,1,25]]},"reference":[{"issue":"3","key":"ref1","first-page":"201","article-title":"Pathophysiology of tinnitus: a special case\u2014hyperacusis and a proposed treatment","volume":"8","author":"JA Vernon","year":"1987","journal-title":"The American journal of otology"},{"issue":"2","key":"ref2","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1044\/jshd.5502.339","article-title":"Hyperacusis and otitis media in individuals with Williams syndrome","volume":"55","author":"AJ Klein","year":"1990","journal-title":"The Journal of speech and hearing disorders"},{"issue":"8","key":"ref3","doi-asserted-by":"crossref","first-page":"545","DOI":"10.3109\/14992020209056075","article-title":"Hypersensitivity to sound (hyperacusis): a prevalence study conducted via the Internet and post","volume":"41","author":"G Andersson","year":"2002","journal-title":"International journal of audiology"},{"issue":"12","key":"ref4","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1177\/014107680309601203","article-title":"Hyperacusis","volume":"96","author":"DM Baguley","year":"2003","journal-title":"Journal of the Royal Society of Medicine"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/00129492-200105000-00009","article-title":"Hyperacusis: review and clinical guidelines","volume":"22","author":"U Katzenell","year":"2001","journal-title":"Otology & neurotology"},{"issue":"4","key":"ref6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1080\/010503999424653","article-title":"Hypersensitivity to sound\u2014questionnaire data, audiometry and classification","volume":"28","author":"M Anari","year":"1999","journal-title":"Scand Audiol"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1055\/s-0042-1748042","article-title":"Tinnitus Retraining Therapy (TRT) as a method for treatment of tinnitus and hyperacusis patients","volume":"11","author":"PJ Jastreboff","year":"2000","journal-title":"Journal of the American Academy of Audiology"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.heares.2017.08.002","article-title":"No auditory experience, no tinnitus: Lessons from subjects with congenital- and acquired single-sided deafness","volume":"354","author":"SY Lee","year":"2017","journal-title":"Hear Res"},{"issue":"1\u20132","key":"ref9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0378-5955(00)00235-5","article-title":"A biochemical model of peripheral tinnitus","volume":"152","author":"TL Sahley","year":"2001","journal-title":"Hear Res"},{"issue":"10","key":"ref10","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1179\/174313209X383303","article-title":"Plasticity diseases","volume":"31","author":"AR Moller","year":"2009","journal-title":"Neurol Res"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.pneurobio.2013.08.002","article-title":"Advances in the neurobiology of hearing disorders: recent developments regarding the basis of tinnitus and hyperacusis","volume":"111","author":"M Knipper","year":"2013","journal-title":"Progress in neurobiology"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.brainres.2012.02.008","article-title":"Noise exposure enhances auditory cortex responses related to hyperacusis behavior","volume":"1485","author":"W Sun","year":"2012","journal-title":"Brain research"},{"issue":"4","key":"ref13","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.neuroscience.2009.12.063","article-title":"Neural changes in the auditory cortex of awake guinea pigs after two tinnitus inducers: salicylate and acoustic trauma","volume":"166","author":"AJ Norena","year":"2010","journal-title":"Neuroscience"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"e06576","DOI":"10.7554\/eLife.06576","article-title":"Tinnitus and hyperacusis involve hyperactivity and enhanced connectivity in auditory-limbic-arousal-cerebellar network","volume":"4","author":"YC Chen","year":"2015","journal-title":"eLife"},{"issue":"6","key":"ref15","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.amjoto.2008.08.005","article-title":"Brain activation in patients with idiopathic hyperacusis","volume":"30","author":"JH Hwang","year":"2009","journal-title":"American journal of otolaryngology"},{"issue":"6","key":"ref16","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1152\/jn.00226.2010","article-title":"Tinnitus, diminished sound-level tolerance, and elevated auditory activity in humans with clinically normal hearing sensitivity","volume":"104","author":"JW Gu","year":"2010","journal-title":"J Neurophysiol"},{"issue":"3","key":"ref17","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1007\/s00429-013-0555-1","article-title":"Hyperacusis-associated pathological resting-state brain oscillations in the tinnitus brain: a hyperresponsiveness network with paradoxically inactive auditory cortex","volume":"219","author":"JJ Song","year":"2014","journal-title":"Brain structure & function"},{"issue":"9","key":"ref18","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1523\/JNEUROSCI.5587-06.2007","article-title":"Dissociable intrinsic connectivity networks for salience processing and executive control","volume":"27","author":"WW Seeley","year":"2007","journal-title":"J Neurosci"},{"issue":"12","key":"ref19","doi-asserted-by":"crossref","first-page":"4690","DOI":"10.1073\/pnas.1113455109","article-title":"Salience network integrity predicts default mode network function after traumatic brain injury","volume":"109","author":"V Bonnelle","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"34","key":"ref20","doi-asserted-by":"crossref","first-page":"12569","DOI":"10.1073\/pnas.0800005105","article-title":"A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks","volume":"105","author":"D Sridharan","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"ref21","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.neulet.2005.06.069","article-title":"Obsessive-compulsive dimension localized using low-resolution brain electromagnetic tomography (LORETA)","volume":"387","author":"L Sherlin","year":"2005","journal-title":"Neurosci Lett"},{"issue":"9","key":"ref22","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1016\/j.clinph.2011.01.051","article-title":"EEG source analysis in obsessive-compulsive disorder","volume":"122","author":"J Koprivova","year":"2011","journal-title":"Clin Neurophysiol"},{"issue":"3","key":"ref23","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1162\/jocn_a_00098","article-title":"Brain oscillatory activity during spatial navigation: theta and gamma activity link medial temporal and parietal regions","volume":"24","author":"DJ White","year":"2012","journal-title":"Journal of cognitive neuroscience"},{"issue":"1","key":"ref24","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1176\/ajp.157.1.75","article-title":"Association between age-related decline in brain dopamine activity and impairment in frontal and cingulate metabolism","volume":"157","author":"ND Volkow","year":"2000","journal-title":"Am J Psychiatry"},{"issue":"3","key":"ref25","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1159\/000054958","article-title":"Effects of caffeine on topographic quantitative EEG","volume":"45","author":"M Siepmann","year":"2002","journal-title":"Neuropsychobiology"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1471-2202-11-40","article-title":"Temporo-insular enhancement of EEG low and high frequencies in patients with chronic tinnitus. QEEG study of chronic tinnitus patients","volume":"11","author":"M Moazami-Goudarzi","year":"2010","journal-title":"BMC Neurosci"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"29140","DOI":"10.1038\/srep29140","article-title":"Neural substrates predicting short-term improvement of tinnitus loudness and distress after modified tinnitus retraining therapy","volume":"6","author":"SH Kim","year":"2016","journal-title":"Sci Rep"},{"issue":"1","key":"ref28","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s00429-013-0648-x","article-title":"Onset-related differences in neural substrates of tinnitus-related distress: the anterior cingulate cortex in late-onset tinnitus, and the frontal cortex in early-onset tinnitus","volume":"220","author":"JJ Song","year":"2015","journal-title":"Brain Struct Funct"},{"issue":"4","key":"ref29","doi-asserted-by":"crossref","first-page":"e0123538","DOI":"10.1371\/journal.pone.0123538","article-title":"Dysfunctional Noise Cancelling of the Rostral Anterior Cingulate Cortex in Tinnitus Patients","volume":"10","author":"JJ Song","year":"2015","journal-title":"PLoS One"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jneumeth.2015.07.020","article-title":"A novel method for device-related electroencephalography artifact suppression to explore cochlear implant-related cortical changes in single-sided deafness","volume":"255","author":"K Kim","year":"2015","journal-title":"J Neurosci Methods"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.heares.2013.02.001","article-title":"Neural substrates predicting improvement of tinnitus after cochlear implantation in patients with single-sided deafness","volume":"299","author":"JJ Song","year":"2013","journal-title":"Hear Res"},{"issue":"7","key":"ref32","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1016\/j.neurobiolaging.2013.01.014","article-title":""Distressed aging": the differences in brain activity between early- and late-onset tinnitus","volume":"34","author":"JJ Song","year":"2013","journal-title":"Neurobiol Aging"},{"issue":"Suppl D","key":"ref33","first-page":"5","article-title":"Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details","volume":"24","author":"RD Pascual-Marqui","year":"2002","journal-title":"Methods Find Exp Clin Pharmacol"},{"issue":"10","key":"ref34","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.2967\/jnumed.112.102939","article-title":"Mapping tinnitus-related brain activation: an activation-likelihood estimation metaanalysis of PET studies","volume":"53","author":"JJ Song","year":"2012","journal-title":"J Nucl Med"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3389\/fnhum.2017.00210","article-title":"A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus","volume":"11","author":"JJ Song","year":"2017","journal-title":"Front Hum Neurosci"},{"issue":"10","key":"ref36","doi-asserted-by":"crossref","first-page":"e7396","DOI":"10.1371\/journal.pone.0007396","article-title":"Tinnitus intensity dependent gamma oscillations of the contralateral auditory cortex","volume":"4","author":"E van der Loo","year":"2009","journal-title":"PLoS One"},{"issue":"1","key":"ref37","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0167-8760(84)90014-X","article-title":"Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain","volume":"18","author":"RD Pascual-Marqui","year":"1994","journal-title":"Int J Psychophysiol"},{"issue":"5","key":"ref38","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/S1388-2457(02)00030-5","article-title":"A standardized boundary element method volume conductor model","volume":"113","author":"M Fuchs","year":"2002","journal-title":"Clin Neurophysiol"},{"issue":"4","key":"ref39","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1016\/j.neuroimage.2006.09.024","article-title":"10\/20, 10\/10, and 10\/5 systems revisited: their validity as relative head-surface-based positioning systems","volume":"34","author":"V Jurcak","year":"2007","journal-title":"Neuroimage"},{"key":"ref40","article-title":"Co-planar stereotaxic atlas of the human brain: 3-Dimensional proportional system: An approach to cerebral imaging","author":"J Talairach","year":"1988"},{"issue":"4","key":"ref41","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/35067550","article-title":"The brainweb: phase synchronization and large-scale integration","volume":"2","author":"F Varela","year":"2001","journal-title":"Nature reviews Neuroscience"},{"issue":"6","key":"ref42","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1002\/hbm.21284","article-title":"Relationship of resting EEG with anatomical MRI measures in individuals at high and low risk for depression","volume":"33","author":"GE Bruder","year":"2012","journal-title":"Hum Brain Mapp"},{"key":"ref43","unstructured":"Pascual-Marqui RD. Instantaneous and lagged measurements of linear and nonlinear dependence between groups of multivariate time series: frequency decomposition. Arxiv preprint arXiv:07111455. 2007."},{"issue":"1","key":"ref44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/hbm.1058","article-title":"Nonparametric permutation tests for functional neuroimaging: a primer with examples","volume":"15","author":"TE Nichols","year":"2002","journal-title":"Hum Brain Mapp"},{"issue":"3","key":"ref45","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1111\/j.1460-9568.2010.07542.x","article-title":"Rapid increases of gamma power in the auditory cortex following noise trauma in humans","volume":"33","author":"M Ortmann","year":"2011","journal-title":"Eur J Neurosci"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.brainres.2009.09.089","article-title":"Auditory cortex stimulation by low-frequency tones-an fMRI study","volume":"1304","author":"E Dommes","year":"2009","journal-title":"Brain Res"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ijpsycho.2015.02.006","article-title":"Decrease of delta oscillatory responses is associated with increased age in healthy elderly","volume":"103","author":"DD Emek-Savas","year":"2016","journal-title":"Int J Psychophysiol"},{"issue":"1","key":"ref48","first-page":"101","article-title":"Spontaneous brain magnetic activity in schizophrenia patients treated with aripiprazole","volume":"34","author":"JM Canive","year":"1998","journal-title":"Psychopharmacol Bull"},{"issue":"3","key":"ref49","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nrn755","article-title":"Control of goal-directed and stimulus-driven attention in the brain","volume":"3","author":"M Corbetta","year":"2002","journal-title":"Nat Rev Neurosci"},{"issue":"10","key":"ref50","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1097\/MAO.0000000000000560","article-title":"Neural Substrates of Conversion Deafness in a Cochlear Implant Patient: A Molecular Imaging Study Using H215O-PET","volume":"35","author":"JJ Song","year":"2014","journal-title":"Otol Neurotol"},{"issue":"5","key":"ref51","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1002\/hbm.22750","article-title":"The role of the salience network in processing lexical and nonlexical stimuli in cochlear implant users: An ALE Meta-Analysis of PET Studies","volume":"36","author":"JJ Song","year":"2015","journal-title":"Hum Brain Mapp"},{"issue":"5596","key":"ref52","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1126\/science.1076358","article-title":"Emotion, cognition, and behavior","volume":"298","author":"RJ Dolan","year":"2002","journal-title":"Science"},{"issue":"8","key":"ref53","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1007\/s00702-011-0606-9","article-title":"Brain activity associated with pain, hyperalgesia and allodynia: an ALE meta-analysis","volume":"118","author":"S Lanz","year":"2011","journal-title":"Journal of neural transmission (Vienna, Austria: 1996)"},{"issue":"5","key":"ref54","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1111\/psyp.12604","article-title":"Stimulus sequence context differentially modulates inhibition-related theta and delta band activity in a go\/no-go task","volume":"53","author":"J Harper","year":"2016","journal-title":"Psychophysiology"},{"issue":"4","key":"ref55","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1016\/j.neuroscience.2009.09.057","article-title":"Event-related delta and theta synchronization during explicit and implicit emotion processing","volume":"164","author":"GG Knyazev","year":"2009","journal-title":"Neuroscience"},{"issue":"4","key":"ref56","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1093\/schbul\/sbr056","article-title":"High vs low frequency neural oscillations in schizophrenia","volume":"37","author":"LV Moran","year":"2011","journal-title":"Schizophr Bull"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0191858","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,13]],"date-time":"2022-08-13T06:07:20Z","timestamp":1660370840000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0191858"}},"subtitle":[],"editor":[{"given":"Lutz","family":"J\u00e4ncke","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,1,25]]},"references-count":56,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,1,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0191858","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,25]]}}}