{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T04:27:47Z","timestamp":1786768067631,"version":"build-2736575974"},"reference-count":92,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T00:00:00Z","timestamp":1520208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001322","name":"South African Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004695","name":"University of KwaZulu-Natal","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004695","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0193833","type":"journal-article","created":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T18:31:21Z","timestamp":1520274681000},"page":"e0193833","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":11,"title":["Phosphoethanolamine-N-methyltransferase is a potential biomarker for the diagnosis of P. knowlesi and P. falciparum malaria"],"prefix":"10.1371","volume":"13","author":[{"given":"Robert G. E.","family":"Krause","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6713-9515","authenticated-orcid":true,"given":"J. P. Dean","family":"Goldring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2018,3,5]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.ympev.2007.11.012","article-title":"A three-genome phylogeny of malaria parasites (<italic>Plasmodium<\/italic> and closely related genera): evolution of life-history traits and host switches","volume":"47","author":"ES Martinsen","year":"2008","journal-title":"Mol. Phylogenet. 2008; Evol"},{"key":"ref2","unstructured":"World Health Organization (2016) World malaria report 2016. Geneva: World Health Organization."},{"key":"ref3","first-page":"301","article-title":"A study of monkey-malaria and its experimental transmission to man","volume":"67","author":"R Knowles","year":"1932","journal-title":"Ind Med Gaz"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1126\/science.149.3686.865","article-title":"A Naturally Acquired Quotidian-Type Malaria in Man Transferable to Monkeys","volume":"149","author":"W Chin","year":"1965","journal-title":"Science"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/S0140-6736(04)15836-4","article-title":"A large focus of naturally acquired <italic>Plasmodium knowlesi<\/italic> infections in human beings","volume":"363","author":"B Singh","year":"2004","journal-title":"Lancet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1086\/524889","article-title":"<italic>Plasmodium knowlesi<\/italic>: the fifth human malaria parasite","volume":"46","author":"NJ White","year":"2008","journal-title":"Clin. Infect. Dis"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"e1002015","DOI":"10.1371\/journal.ppat.1002015","article-title":"<italic>Plasmodium knowlesi<\/italic>: reservoir hosts and tracking the emergence in humans and macaques","volume":"7","author":"KS Lee","year":"2011","journal-title":"PLoS pathog"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"e83","DOI":"10.1016\/S2542-5196(17)30053-0","article-title":"Identifying the risks for human transmission of <italic>Plasmodium knowlesi<\/italic>","volume":"1","author":"J Richards","year":"2017","journal-title":"Lancet Planet. Health"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"e97","DOI":"10.1016\/S2542-5196(17)30031-1","article-title":"Individual-level factors associated with the risk of acquiring human <italic>Plasmodium knowlesi<\/italic> malaria in Malaysia: a case-control study","volume":"1","author":"MJ Grigg","year":"2017","journal-title":"Lancet Planet. Health"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1186\/1475-2875-13-168","article-title":"High proportion of <italic>knowlesi<\/italic> malaria in recent malaria cases in Malaysia","volume":"13","author":"R Yusof","year":"2014","journal-title":"Malar J"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.3201\/eid1710.110355","article-title":"<italic>Plasmodium knowlesi<\/italic> infection in humans, Cambodia, 2007\u20132010","volume":"17","author":"N Khim","year":"2011","journal-title":"Emerg. Infect. Dis"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"672","DOI":"10.3201\/eid1604.091624","article-title":"<italic>Plasmodium knowlesi<\/italic> in human, Indonesian Borneo","volume":"16","author":"M Figtree","year":"2010","journal-title":"Emerg. Infect. Dis"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.3201\/eid1609.100339","article-title":"Co-infections with <italic>Plasmodium knowlesi<\/italic> and other malaria parasites, Myanmar","volume":"16","author":"N Jiang","year":"2010","journal-title":"Emerg. Infect. Dis"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"811","DOI":"10.3201\/eid1405.071407","article-title":"Human Infections with <italic>Plasmodium knowlesi<\/italic>, the Philippines","volume":"14","author":"J Luchavez","year":"2008","journal-title":"Emerg. Infect. Dis"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1089\/vbz.2010.0024","article-title":"Molecular epidemiological investigation of <italic>Plasmodium knowlesi<\/italic> in humans and macaques in Singapore","volume":"11","author":"WP Jeslyn","year":"2011","journal-title":"Vector Borne Zoonotic Dis"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.3201\/eid1710.110349","article-title":"<italic>Plasmodium knowlesi<\/italic> Malaria in humans and macaques, Thailand","volume":"17","author":"S Jongwutiwes","year":"2011","journal-title":"Emerg. Infect. Dis"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1475-2875-11-36","article-title":"Human <italic>Plasmodium knowlesi<\/italic> infection in Ranong province, southwestern border of Thailand","volume":"11","author":"N Sermwittayawong","year":"2012","journal-title":"Malar J"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.3201\/eid1707.101551","article-title":"Co-infections of <italic>Plasmodium knowlesi<\/italic>, <italic>P<\/italic>. <italic>falciparum<\/italic>, and <italic>P<\/italic>. <italic>vivax<\/italic> among Humans and Anopheles dirus Mosquitoes, Southern Vietnam","volume":"17","author":"RP Marchand","year":"2011","journal-title":"Emerg. Infect. Dis"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1128\/JCM.00181-14","article-title":"Combining parasite lactate dehydrogenase-based and histidine-rich protein 2-based rapid tests to improve specificity for diagnosis of malaria Due to <italic>Plasmodium knowlesi<\/italic> and other <italic>Plasmodium<\/italic> species in Sabah, Malaysia","volume":"52","author":"MJ Grigg","year":"2014","journal-title":"J Clin Microbiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/0035-9203(71)90103-9","article-title":"A presumptive case of naturally occurring <italic>Plasmodium knowlesi<\/italic> malaria in man in Malaysia","volume":"65","author":"YL Fong","year":"1971","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1093\/infdis\/jiv475","article-title":"Asymptomatic and Submicroscopic Carriage of <italic>Plasmodium knowlesi<\/italic> Malaria in Household and Community Members of Clinical Cases in Sabah, Malaysia","volume":"213","author":"KM Fornace","year":"2016","journal-title":"J Infect Dis"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1071\/MA16014","article-title":"<italic>Plasmodium knowlesi<\/italic>: an update","author":"B Singh","year":"2016","journal-title":"Microbiology Australia"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"43779","DOI":"10.1038\/srep43779","article-title":"A new malaria vector mosquito in South Africa","volume":"7","author":"A Burke","year":"2017","journal-title":"Sci. Rep"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/1475-2875-8-73","article-title":"Morphological features and differential counts of <italic>Plasmodium knowlesi<\/italic> parasites in naturally acquired human infections","volume":"8","author":"KS Lee","year":"2009","journal-title":"Malar J"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1128\/CMR.00079-12","article-title":"Human infections and detection of <italic>Plasmodium knowlesi<\/italic>","volume":"26","author":"B Singh","year":"2013","journal-title":"Clin. Microbiol. Rev"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/ajh.24697","article-title":"Plasmodium knowlesi","volume":"92","author":"P Chiodini","year":"2017","journal-title":"American journal of hematology"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1086\/524888","article-title":"<italic>Plasmodium knowlesi<\/italic> malaria in humans is widely distributed and potentially life threatening","volume":"46","author":"J Cox-Singh","year":"2008","journal-title":"Clin. Infect. Dis"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1086\/605439","article-title":"Clinical and laboratory features of human <italic>Plasmodium knowlesi<\/italic> infection","volume":"49","author":"C Daneshvar","year":"2009","journal-title":"Clin. Infect. Dis"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1186\/1475-2875-12-425","article-title":"Susceptibility of human <italic>Plasmodium knowlesi<\/italic> infections to anti-malarials","volume":"12","author":"FA Fatih","year":"2013","journal-title":"Malar J"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/cid\/cis902","article-title":"A prospective comparative study of <italic>knowlesi<\/italic>, <italic>falciparum<\/italic>, and <italic>vivax<\/italic> malaria in Sabah, Malaysia: high proportion with severe disease from <italic>Plasmodium knowlesi<\/italic> and <italic>Plasmodium vivax<\/italic> but no mortality with early referral and artesunate therapy","volume":"56","author":"BE Barber","year":"2013","journal-title":"Clinical infectious diseases"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1186\/1475-2875-8-253","article-title":"Hyperparasitaemia and low dosing are an important source of anti-malarial drug resistance","volume":"8","author":"NJ White","year":"2009","journal-title":"Malar J"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1128\/CMR.15.1.66-78.2002","article-title":"Rapid diagnostic tests for malaria parasites","volume":"15","author":"A Moody","year":"2002","journal-title":"Clin. Microbiol. Rev"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1099\/jmm.0.052506-0","article-title":"Malaria rapid diagnostic tests: challenges and prospects","volume":"62","author":"JC Mouatcho","year":"2013","journal-title":"J. Med. Microbiol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.3201\/eid1411.080840","article-title":"Use of malaria rapid diagnostic test to identify <italic>Plasmodium knowlesi<\/italic> infection","volume":"14","author":"TF McCutchan","year":"2008","journal-title":"Emerg. Infect. Dis"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4269\/ajtmh.1999.60.109","article-title":"Immunocapture diagnostic assays for malaria using <italic>Plasmodium<\/italic> lactate dehydrogenase (pLDH)","volume":"60","author":"R Piper","year":"1999","journal-title":"Am J Trop Med Hyg"},{"key":"ref36","first-page":"6","article-title":"Monoclonal antibodies against lactate dehydrogenase of <italic>Plasmodium knowlesi<\/italic>","volume":"33","author":"DC Kaushal","year":"1995","journal-title":"Indian J Exp Biol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.pep.2012.05.008","article-title":"Cloning, overexpression, purification and characterization of <italic>Plasmodium knowlesi<\/italic> lactate dehydrogenase","volume":"84","author":"V Singh","year":"2012","journal-title":"Protein Expr Purif"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1475-2875-13-60","article-title":"Evaluation of three rapid diagnostic tests for the detection of human infections with <italic>Plasmodium knowlesi<\/italic>","volume":"13","author":"D Foster","year":"2014","journal-title":"Malar J"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.peptides.2010.01.002","article-title":"Anti-peptide antibodies differentiate between plasmodial lactate dehydrogenases","volume":"31","author":"R Hurdayal","year":"2010","journal-title":"Peptides"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.exppara.2017.05.007","article-title":"<italic>Plasmodium<\/italic> glyceraldehyde-3-phosphate dehydrogenase: A potential malaria diagnostic target","volume":"179","author":"RGE Krause","year":"2017","journal-title":"Exp Parasitol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"120","DOI":"10.4269\/ajtmh.15-0670","article-title":"A Sensitive, Colorimetric, High-Throughput Loop-Mediated Isothermal Amplification Assay for the Detection of <italic>Plasmodium knowlesi<\/italic>","volume":"95","author":"S Britton","year":"2016","journal-title":"Am J Trop Med Hyg"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"336","DOI":"10.4269\/ajtmh.15-0569","article-title":"Loop-Mediated Isothermal Amplification Assay for Identification of Five Human <italic>Plasmodium<\/italic> Species in Malaysia","volume":"94","author":"YL Lau","year":"2016","journal-title":"Am J Trop Med Hyg"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1128\/JCM.00331-10","article-title":"Evaluation of a loop-mediated isothermal amplification method as a tool for diagnosis of infection by the zoonotic simian malaria parasite <italic>Plasmodium knowlesi<\/italic>","volume":"48","author":"H Iseki","year":"2010","journal-title":"J Clin Microbiol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s12936-016-1676-9","article-title":"Detection of <italic>Plasmodium knowlesi<\/italic>, <italic>Plasmodium falciparum<\/italic> and <italic>Plasmodium vivax<\/italic> using loop-mediated isothermal amplification (LAMP) in a co-endemic area in Malaysia","volume":"16","author":"KA Piera","year":"2017","journal-title":"Malar J"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1186\/1475-2875-10-197","article-title":"Specific, sensitive and rapid detection of human <italic>Plasmodium knowlesi<\/italic> infection by loop-mediated isothermal amplification (LAMP) in blood samples","volume":"10","author":"YL Lau","year":"2011","journal-title":"Malar J"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"6206","DOI":"10.1073\/pnas.0307742101","article-title":"A pathway for phosphatidylcholine biosynthesis in <italic>Plasmodium falciparum<\/italic> involving phosphoethanolamine methylation","volume":"101","author":"G Pessi","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1111\/j.1574-6976.2011.00267.x","article-title":"Phosphoethanolamine methyltransferases in phosphocholine biosynthesis: functions and potential for antiparasite therapy","volume":"35","author":"AM Bobenchik","year":"2011","journal-title":"FEMS Microbiol Rev"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"18262","DOI":"10.1073\/pnas.1313965110","article-title":"<italic>Plasmodium falciparum<\/italic> phosphoethanolamine methyltransferase is essential for malaria transmission","volume":"110","author":"AM Bobenchik","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.cell.2017.06.030","article-title":"Functional Profiling of a <italic>Plasmodium<\/italic> Genome Reveals an Abundance of Essential Genes","volume":"170","author":"E Bushell","year":"2017","journal-title":"Cell"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"27636","DOI":"10.1074\/jbc.M804360200","article-title":"Disruption of the <italic>Plasmodium falciparum<\/italic> PfPMT gene results in a complete loss of phosphatidylcholine biosynthesis via the serine-decarboxylase-phosphoethanolamine-methyltransferase pathway and severe growth and survival defects","volume":"283","author":"WH Witola","year":"2008","journal-title":"J. Biol. Chem"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"12461","DOI":"10.1074\/jbc.M414626200","article-title":"In vivo evidence for the specificity of <italic>Plasmodium falciparum<\/italic> phosphoethanolamine methyltransferase and its coupling to the Kennedy pathway","volume":"280","author":"G Pessi","year":"2005","journal-title":"J. Biol. Chem"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1471-2091-11-4","article-title":"Identification of inhibitors of <italic>Plasmodium falciparum<\/italic> phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay","volume":"11","author":"AM Bobenchik","year":"2010","journal-title":"BMC Biochem"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1194\/jlr.M900166-JLR200","article-title":"Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways","volume":"51","author":"S Dechamps","year":"2010","journal-title":"J. Lipid Res"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"9064","DOI":"10.1038\/srep09064","article-title":"Structure, function and inhibition of the phosphoethanolamine methyltransferases of the human malaria parasites <italic>Plasmodium vivax<\/italic> and <italic>Plasmodium knowlesi<\/italic>","volume":"5","author":"A Garg","year":"2015","journal-title":"Sci. Rep"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"4990","DOI":"10.1016\/j.bmcl.2012.06.032","article-title":"Crystal structure of phosphoethanolamine methyltransferase from <italic>Plasmodium falciparum<\/italic> in complex with amodiaquine. Bioorganic Med","volume":"22","author":"SG Lee","year":"2012","journal-title":"Chem. Lett"},{"key":"ref56","article-title":"Quantitative time-course profiling of parasite and host cell proteins in the human malaria parasite <italic>Plasmodium falciparum<\/italic>","volume":"10","author":"BJ Foth","year":"2011","journal-title":"Mol. Cell. Proteomics"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1126\/science.1087025","article-title":"Discovery of gene function by expression profiling of the malaria parasite life cycle","volume":"301","author":"KG Le Roch","year":"2003","journal-title":"Science"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/0006-291X(89)90049-1","article-title":"Predict7, a program for protein structure prediction","volume":"159","author":"RS Carmenes","year":"1989","journal-title":"Biochem Biophys Res Commun"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1074\/jbc.M111.315267","article-title":"Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite <italic>Plasmodium falciparum<\/italic>: an antiparasitic drug target","volume":"287","author":"SG Lee","year":"2012","journal-title":"J. Biol. Chem"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.pep.2005.01.016","article-title":"Protein production by auto-induction in high density shaking cultures","volume":"41","author":"FW Studier","year":"2005","journal-title":"Protein Expr Purif"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.1096\/fasebj.4.8.1970792","article-title":"Efficient production of chicken egg yolk antibodies against a conserved mammalian protein","volume":"4","author":"M Gassmann","year":"1990","journal-title":"FASEB J"},{"key":"ref62","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-662-04488-9","article-title":"Chicken Egg Yolk Antibodies, Production and Application","author":"R Schade","year":"2001"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"627","DOI":"10.3109\/08820139.2015.1070268","article-title":"Comparing Antibody Responses in Chickens Against <italic>Plasmodium falciparum<\/italic> Lactate Dehydrogenase and Glyceraldehyde-3-phosphate Dehydrogenase with Freund\u2019s and Pheroid(R) Adjuvants","volume":"44","author":"RG Krause","year":"2015","journal-title":"Immunol. Invest"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"UK Laemmli","year":"1970","journal-title":"Nature"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/978-1-61779-821-4_53","article-title":"Rapid detection of proteins in polyacrylamide electrophoresis gels with Direct Red 81 and Amido Black","volume":"869","author":"D Choveaux","year":"2012","journal-title":"Methods Mol Biol"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications","volume":"76","author":"H Towbin","year":"1979","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"MM Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/bmb.2003.494031030213","article-title":"Isolation of Chicken Immunoglobulins (IgY) from Egg Yolk","volume":"31","author":"JP Goldring","year":"2003","journal-title":"Biochem Mol Biol Educ"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1128\/CDLI.11.5.919-923.2004","article-title":"Mass value assignment of total and subclass immunoglobulin G in a human standard anthrax reference serum","volume":"11","author":"VA Semenova","year":"2004","journal-title":"Clin Diagn Lab Immunol"},{"key":"ref70","first-page":"Unit 5 1","article-title":"Handling, storage, and preparation of human blood cells","volume":"Chapter 5","author":"JP McCoy Jr.","year":"2001","journal-title":"Current protocols in cytometry"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0022-1759(83)90292-2","article-title":"A convenient enzyme-linked immunosorbent assay for testing whether monoclonal antibodies recognize the same antigenic site. Application to hybridomas specific for the beta 2-subunit of <italic>Escherichia coli<\/italic> tryptophan synthase","volume":"60","author":"B Friguet","year":"1983","journal-title":"J Immunol Methods"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1365-2141.1992.tb08249.x","article-title":"<italic>Plasmodium falciparum<\/italic>: diversity of isolates from Malawi in their cytoadherence to melanoma cells and monocytes in vitro","volume":"81","author":"JD Goldring","year":"1992","journal-title":"Br. J. Haematol"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/j.1365-2249.1992.tb05851.x","article-title":"Intravenous immunoglobulin in the treatment of paediatric cerebral malaria","volume":"90","author":"TE Taylor","year":"1992","journal-title":"Clin Exp Immunol"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.exppara.2014.11.001","article-title":"Identification and initial characterisation of a <italic>Plasmodium falciparum<\/italic> Cox17 copper metallochaperone","volume":"148","author":"DL Choveaux","year":"2015","journal-title":"Exp Parasitol"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"D539","DOI":"10.1093\/nar\/gkn814","article-title":"PlasmoDB: a functional genomic database for malaria parasites","volume":"37","author":"C Aurrecoechea","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1086\/432010","article-title":"Genetic diversity of <italic>Plasmodium falciparum<\/italic> histidine-rich protein 2 (PfHRP2) and its effect on the performance of PfHRP2-based rapid diagnostic tests","volume":"192","author":"J Baker","year":"2005","journal-title":"J Infect Dis"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"e8091","DOI":"10.1371\/journal.pone.0008091","article-title":"A large proportion of <italic>P<\/italic>. <italic>falciparum<\/italic> isolates in the Amazon region of Peru lack pfhrp2 and pfhrp3: implications for malaria rapid diagnostic tests","volume":"5","author":"D Gamboa","year":"2010","journal-title":"PloS one"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.actatropica.2012.09.015","article-title":"Genetic deletion of HRP2 and HRP3 in Indian <italic>Plasmodium falciparum<\/italic> population and false negative malaria rapid diagnostic test","volume":"125","author":"N Kumar","year":"2013","journal-title":"Acta Trop"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1475-2875-13-34","article-title":"Analysis of pfhrp2 genetic diversity in Senegal and implications for use of rapid diagnostic tests","volume":"13","author":"AB Deme","year":"2014","journal-title":"Malar J"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0969-2126(01)00643-8","article-title":"Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons","volume":"9","author":"JR Horton","year":"2001","journal-title":"Structure"},{"key":"ref81","first-page":"977","article-title":"Detection of histidine rich protein &amp; lactate dehydrogenase of <italic>Plasmodium falciparum<\/italic> in malaria patients by sandwich ELISA using in-house reagents","volume":"138","author":"P Verma","year":"2013","journal-title":"Indian J. Med. Res"},{"key":"ref82","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1186\/1475-2875-13-277","article-title":"Production and characterization of specific monoclonal antibodies binding the <italic>Plasmodium falciparum<\/italic> diagnostic biomarker, histidine-rich protein 2","volume":"13","author":"CH Leow","year":"2014","journal-title":"Malar J"},{"key":"ref83","doi-asserted-by":"crossref","first-page":"171","DOI":"10.4269\/ajtmh.1999.61.171","article-title":"Characterization of monoclonal antibodies to an immunodominant protein of the etiologic agent of human granulocytic ehrlichiosis","volume":"61","author":"MD Ravyn","year":"1999","journal-title":"Am J Trop Med Hyg"},{"key":"ref84","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3109\/03009739909178961","article-title":"Chicken antibodies: a clinical chemistry perspective","volume":"104","author":"D Carlander","year":"1999","journal-title":"Ups J Med Sci"},{"key":"ref85","doi-asserted-by":"crossref","first-page":"516","DOI":"10.4269\/ajtmh.2009.80.516","article-title":"Unified parasite lactate dehydrogenase and histidine-rich protein ELISA for quantification of <italic>Plasmodium falciparum<\/italic>","volume":"80","author":"SK Martin","year":"2009","journal-title":"Am J Trop Med Hyg"},{"key":"ref86","article-title":"Malaria parasite metabolic pathways Israel","author":"H Ginsburg","year":"2017"},{"key":"ref87","doi-asserted-by":"crossref","first-page":"21305","DOI":"10.1074\/jbc.M603260200","article-title":"Localization of the phosphoethanolamine methyltransferase of the human malaria parasite <italic>Plasmodium falciparum<\/italic> to the Golgi apparatus","volume":"281","author":"WH Witola","year":"2006","journal-title":"J. Biol. Chem"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1128\/EC.00229-07","article-title":"Choline induces transcriptional repression and proteasomal degradation of the malarial phosphoethanolamine methyltransferase","volume":"6","author":"WH Witola","year":"2007","journal-title":"Eukaryot Cell"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1186\/1475-2875-8-241","article-title":"Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of <italic>falciparum<\/italic> and <italic>vivax<\/italic> malaria","volume":"8","author":"EA Ashley","year":"2009","journal-title":"Malar J"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1186\/1475-2875-12-349","article-title":"Usefulness of <italic>Plasmodium falciparum<\/italic>-specific rapid diagnostic tests for assessment of parasite clearance and detection of recurrent infections after artemisinin-based combination therapy","volume":"12","author":"B Aydin-Schmidt","year":"2013","journal-title":"Malar J"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1186\/1475-2875-13-480","article-title":"Circulating antibodies against <italic>Plasmodium falciparum<\/italic> histidine-rich proteins 2 interfere with antigen detection by rapid diagnostic tests","volume":"13","author":"MF Ho","year":"2014","journal-title":"Malar J"},{"key":"ref92","doi-asserted-by":"crossref","first-page":"416","DOI":"10.4161\/mabs.12438","article-title":"Recombinant antibodies specific for the <italic>Plasmodium falciparum<\/italic> histidine-rich protein 2","volume":"2","author":"E Ravaoarisoa","year":"2010","journal-title":"mAbs"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0193833","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:10:54Z","timestamp":1603930254000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0193833"}},"subtitle":[],"editor":[{"given":"\u00c9rika Martins","family":"Braga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,3,5]]},"references-count":92,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,3,5]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0193833","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,5]]}}}